Expert Opinion on Drug Discovery, Volume 16, Issue 2 (2021)

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Expert Opinion on Drug Discovery, Volume 16, Issue 2 (2021)

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Editorial

Editorial
Are open-source approaches the most efficient way forward for COVID-19 drug discovery?
Amer Harky, Vaibhav Mishra, Daniyal Matin Ansari & Naomi Melamed
Pages: 115-117
Published online: 11 Sep 2020
AbstractforAre open-source approaches the most efficient way forward for COVID-19 drug discovery? | Full Text | References | PDF (172.3 KB) | EPUB
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Editorial
What are the practical, ethical, and pathobiological considerations in the use of minipigs as an animal model in drug discovery for acute radiation syndrome and delayed effects of acute radiation exposure?
Doreswamy Kenchegowda, Thomas M. Seed & Vijay K. Singh
Pages: 119-124
Published online: 06 Sep 2020
First Page PreviewforWhat are the practical, ethical, and pathobiological considerations in the use of minipigs as an animal model in drug discovery for acute radiation syndrome and delayed effects of acute radiation exposure? | Full Text | References | PDF (229.4 KB) | EPUB
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Perspective

Drug development of nonalcoholic fatty liver disease: challenges in research, regulatory pathways, and study endpoints
Albert Do, Ysabel C. Ilagan-Ying, Wajahat Z. Mehal & Joseph K. Lim
Pages: 125-134
Published online: 22 Oct 2020
AbstractforDrug development of nonalcoholic fatty liver disease: challenges in research, regulatory pathways, and study endpoints | Full Text | References | PDF (1.3 MB) | EPUB
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Review

Animal models for the discovery of novel drugs for post-traumatic stress disorder
Phillip R. Zoladz
Pages: 135-146
Published online: 14 Sep 2020
AbstractforAnimal models for the discovery of novel drugs for post-traumatic stress disorder | Full Text | References | PDF (417.5 KB) | EPUB
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Targeting metabotropic glutamate receptors for rapid-acting antidepressant drug discovery
Laura Musazzi
Pages: 147-157
Published online: 23 Sep 2020
AbstractforTargeting metabotropic glutamate receptors for rapid-acting antidepressant drug discovery | Full Text | References | PDF (729.1 KB) | EPUB
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Disentangling the fibrous microenvironment: designer culture models for improved drug discovery
Carley Ort, Wontae Lee, Nikita Kalashnikov & Christopher Moraes
Pages: 159-171
Published online: 29 Sep 2020
AbstractforDisentangling the fibrous microenvironment: designer culture models for improved drug discovery | Full Text | References | PDF (3.3 MB) | EPUB
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Targeting the BAF complex in advanced prostate cancer
Andrew Hartley, Hing Y. Leung & Imran Ahmad
Pages: 173-181
Published online: 16 Sep 2020
AbstractforTargeting the BAF complex in advanced prostate cancer | Full Text | References | PDF (3.1 MB) | EPUB
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An update of cyclic nucleotide phosphodiesterase as a target for cardiac diseases
Si Chen & Chen Yan
Pages: 183-196
Published online: 21 Sep 2020
AbstractforAn update of cyclic nucleotide phosphodiesterase as a target for cardiac diseases | Full Text | References | PDF (1.8 MB) | EPUB
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How not to discover a drug - integrins
Dermot Cox
Pages: 197-211
Published online: 14 Sep 2020
AbstractforHow not to discover a drug - integrins | Full Text | References | PDF (956.7 KB) | EPUB
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