Expert Opinion on Drug Discovery, Volume 19, Issue 7 (2024)

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Expert Opinion on Drug Discovery, Volume 19, Issue 7 (2024)

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Editorial

Editorial
On-demand modular assembly for expedited PROTAC development
Ayan Mukherjee, Vilas D. Kadam, Qi Miao, Wanheng Zhang, Kevin R. MacKenzie, Zhi Tan & Mingxing Teng
Pages: 769-772
Published online: 06 Jun 2024
First Page PreviewforOn-demand modular assembly for expedited PROTAC development | Full Text | References | PDF (184.3 KB) | EPUB
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Free Access

Drug Discovery Case History

Article
Inclisiran: the preclinical discovery and development of a novel therapy for the treatment of atherosclerosis
Donatos Tsamoulis, Loukianos S. Rallidis & Constantine E. Kosmas
Pages: 773-782
Published online: 28 May 2024
AbstractforInclisiran: the preclinical discovery and development of a novel therapy for the treatment of atherosclerosis | Full Text | References | PDF (2.2 MB) | EPUB
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Article
The preclinical discovery and development of atogepant for migraine prophylaxis
Carlo Baraldi, Dagmar Beier, Paolo Martelletti & Lanfranco Pellesi
Pages: 783-788
Published online: 10 Jun 2024
AbstractforThe preclinical discovery and development of atogepant for migraine prophylaxis | Full Text | References | PDF (641.2 KB) | EPUB
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Open Access

Perspective

Comment
Bridging the gap between target-based and phenotypic-based drug discovery
Cecília R.C. Calado
Pages: 789-798
Published online: 15 May 2024
AbstractforBridging the gap between target-based and phenotypic-based drug discovery | Full Text | References | PDF (830.3 KB) | EPUB
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Review

Review Article
Hydrophobic tagging of small molecules: an overview of the literature and future outlook
Yang Zhou, Fan Zhou, Shujing Xu, Dazhou Shi, Dang Ding, Shuo Wang, Vasanthanathan Poongavanam, Kai Tang, Xinyong Liu & Peng Zhan
Pages: 799-813
Published online: 02 Jun 2024
AbstractforHydrophobic tagging of small molecules: an overview of the literature and future outlook | Full Text | References | PDF (2.8 MB) | EPUB
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Review Article
Data processing for high-throughput mass spectrometry in drug discovery
Chang Liu & Hui Zhang
Pages: 815-825
Published online: 24 May 2024
AbstractforData processing for high-throughput mass spectrometry in drug discovery | Full Text | References | PDF (4.9 MB) | EPUB
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Review Article
Using induced pluripotent stem cells for drug discovery in arrhythmias
Diogo Teles & Barry M. Fine
Pages: 827-840
Published online: 02 Jun 2024
AbstractforUsing induced pluripotent stem cells for drug discovery in arrhythmias | Full Text | References | PDF (4.5 MB) | EPUB
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Open Access
Review Article
Computer-aided drug discovery strategies for novel therapeutics for prostate cancer leveraging next-generating sequencing data
Weijie Zhang & R. Stephanie Huang
Pages: 841-853
Published online: 11 Jun 2024
AbstractforComputer-aided drug discovery strategies for novel therapeutics for prostate cancer leveraging next-generating sequencing data | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Review Article
Strategies for the design of analogs of auranofin endowed with anticancer potential
Valentina Vitali, Lara Massai & Luigi Messori
Pages: 855-867
Published online: 27 May 2024
AbstractforStrategies for the design of analogs of auranofin endowed with anticancer potential | Full Text | References | PDF (4.4 MB) | EPUB
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