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Volume 17, Issue 6

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 17, Issue 6 (2008)

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Expert Opinion on Investigational Drugs, Volume 17, Issue 6 (2008)

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Reviews

Article

Acetyl-L-carnitine and α-lipoic acid: possible neurotherapeutic agents for mood disorders?

Joanna K Soczynska, Sidney H Kennedy, Cindy SM Chow, Hanna O Woldeyohannes, Jakub Z Konarski & Roger S McIntyre

Pages: 827-843

Published online: 21 May 2008

AbstractforAcetyl-L-carnitine and α-lipoic acid: possible neurotherapeutic agents for mood disorders? | Full Text | References | PDF (172.4 KB)

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Review

Article

Incretin mimetics and dipeptidyl peptidase 4 inhibitors in clinical trials for the treatment of type 2 diabetes

Nasser Mikhail MD MSc

Pages: 845-853

Published online: 21 May 2008

AbstractforIncretin mimetics and dipeptidyl peptidase 4 inhibitors in clinical trials for the treatment of type 2 diabetes | Full Text | References | PDF (136.2 KB)

526 Views
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Article

Novel phosphodiesterase-5 (PDE5) inhibitors in the alleviation of erectile dysfunction due to diabetes and ageing-induced oxidative stress

Serap Gur, Suresh C Sikka & Wayne JG Hellstrom MD FACS

Pages: 855-864

Published online: 21 May 2008

AbstractforNovel phosphodiesterase-5 (PDE5) inhibitors in the alleviation of erectile dysfunction due to diabetes and ageing-induced oxidative stress | Full Text | References | PDF (299.1 KB)

280 Views
18 CrossRef citations
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Article

New Bcr-Abl inhibitors in chronic myeloid leukemia: keeping resistance in check

Thomas O'Hare, Christopher A Eide & Michael W Deininger

Pages: 865-878

Published online: 21 May 2008

AbstractforNew Bcr-Abl inhibitors in chronic myeloid leukemia: keeping resistance in check | Full Text | References | PDF (290.3 KB)

386 Views
56 CrossRef citations
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Article

The potential of proteasome inhibitors in cancer therapy

Jan Sterz, Ivana von Metzler, Jens-Claus Hahne, Britta Lamottke, Jessica Rademacher, Ulrike Heider, Evangelos Terpos & Orhan Sezer

Pages: 879-895

Published online: 21 May 2008

AbstractforThe potential of proteasome inhibitors in cancer therapy | Full Text | References | PDF (214.7 KB)

601 Views
100 CrossRef citations
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Article

Pompholyx: what's new?

Uwe Wollina

Pages: 897-904

Published online: 21 May 2008

AbstractforPompholyx: what's new? | Full Text | References | PDF (131.7 KB)

441 Views
20 CrossRef citations
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Article

The role of urokinase in idiopathic pulmonary fibrosis and implication for therapy

Mehrnaz Gharaee-Kermani DVM MPH PhD, Biao Hu PhD, Sem H Phan MD PhD & Margaret R Gyetko MD

Pages: 905-916

Published online: 21 May 2008

AbstractforThe role of urokinase in idiopathic pulmonary fibrosis and implication for therapy | Full Text | References | PDF (213.4 KB)

442 Views
17 CrossRef citations
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Article

Trans-sodium crocetinate for treating hypoxia/ischemia

John L Gainer PhD

Pages: 917-924

Published online: 21 May 2008

AbstractforTrans-sodium crocetinate for treating hypoxia/ischemia | Full Text | References | PDF (184.3 KB)

226 Views
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Drug Evaluations

Article

Rivaroxaban, an oral direct factor Xa inhibitor

Jonathan P Piccini MD, Manesh R Patel MD, Kenneth W Mahaffey MD, Keith AA Fox MB ChB & Robert M Califf MD

Pages: 925-937

Published online: 21 May 2008

AbstractforRivaroxaban, an oral direct factor Xa inhibitor | Full Text | References | PDF (212.1 KB)

675 Views
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Drug Evaluation

Article

Enzastaurin

Yi-Bin Chen MD & Ann S LaCasce MD

Pages: 939-944

Published online: 21 May 2008

AbstractforEnzastaurin | Full Text | References | PDF (153 KB)

345 Views
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Article

Teduglutide in intestinal adaptation and repair: light at the end of the tunnel

Houssam E Mardini MD MPH & Willem JS de Villiers MD PhD

Pages: 945-951

Published online: 21 May 2008

AbstractforTeduglutide in intestinal adaptation and repair: light at the end of the tunnel | Full Text | References | PDF (132.1 KB)

397 Views
14 CrossRef citations
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Article

Mecobalamin

Yi-Fei Zhang & Guang Ning MD PhD

Pages: 953-964

Published online: 21 May 2008

AbstractforMecobalamin | Full Text | References | PDF (167.3 KB)

1121 Views
38 CrossRef citations
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Key Paper Evaluation

Article

PDE5 inhibitors for cystic fibrosis: can they also enhance chloride transport?

Evaluation of: Lubamba B, Lecourt H, Lebacq J, et al. Preclinical evidence that sildenafi l and vardenafi l activate chloride transport in cystic fi brosis. Am J Respir Crit Care Med 2008;177(5):506–15

Sabina A Antoniu MD

Pages: 965-968

Published online: 21 May 2008

AbstractforPDE5 inhibitors for cystic fibrosis: can they also enhance chloride transport? | Full Text | References | PDF (105.3 KB)

128 Views
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