Expert Opinion on Investigational Drugs, Volume 33, Issue 5 (2024)

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Expert Opinion on Investigational Drugs, Volume 33, Issue 5 (2024)

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Plain Language Summary

Plain Language Summary of Publication
Plain Language Summary of the PAISLEY study: deucravacitinib as a treatment for people with systemic lupus erythematosus
Eric F. Morand, Marilyn Pike, J Merrill, Ronald F van Vollenhoven, Victoria P Werth, Coburn Hobar, Nikolay Delev, Vaishali Shah, Brian Sharkey, Thomas Wegman, Ian Catlett, Subhashis Banerjee & Shalabh Singhal
Pages: 431-440
Published online: 29 May 2024
AbstractforPlain Language Summary of the PAISLEY study: deucravacitinib as a treatment for people with systemic lupus erythematosus | Full Text | PDF (1.3 MB) | EPUB
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Open Access

Review

Review Article
Novel investigational drugs for alopecia areata and future perspectives
Ivana Chim, Ragini Ghiya, Rodney D Sinclair & Samantha Eisman
Pages: 441-449
Published online: 20 May 2024
AbstractforNovel investigational drugs for alopecia areata and future perspectives | Full Text | References | PDF (353.1 KB) | EPUB
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Review Article
Inflammation and Huntington’s disease – a neglected therapeutic target?
Sophie E. Field, Annabel J. Curle & Roger A. Barker
Pages: 451-467
Published online: 29 May 2024
AbstractforInflammation and Huntington’s disease – a neglected therapeutic target? | Full Text | References | PDF (2.3 MB) | EPUB
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Open Access
Review Article
Investigational agents for autosomal dominant polycystic kidney disease: preclinical and early phase study insights
Irene Capelli, Sarah Lerario, Francesca Ciurli, Gian Marco Berti, Valeria Aiello, Michele Provenzano & Gaetano La Manna
Pages: 469-484
Published online: 21 Apr 2024
AbstractforInvestigational agents for autosomal dominant polycystic kidney disease: preclinical and early phase study insights | Full Text | References | PDF (1.4 MB) | EPUB
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Review Article
Sodium/bile acid co-transporter inhibitors currently in preclinical or early clinical development for the treatment of primary biliary cholangitis
Abhishek Gairola, Aaron Wetten & Jessica Dyson
Pages: 485-495
Published online: 24 Apr 2024
AbstractforSodium/bile acid co-transporter inhibitors currently in preclinical or early clinical development for the treatment of primary biliary cholangitis | Full Text | References | PDF (1.6 MB) | EPUB
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Review Article
Experimental and new investigational drugs for the treatment of uterine fibroids
Giulio Evangelisti, Simone Ferrero, Umberto Perrone, Claudio Gustavino, Eugenio Volpi, Alberto Izzotti & Fabio Barra
Pages: 497-508
Published online: 17 Apr 2024
AbstractforExperimental and new investigational drugs for the treatment of uterine fibroids | Full Text | References | PDF (993.9 KB) | EPUB
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Review Article
Investigational drugs for the treatment of acromegaly: new agents to transform therapy
Rosa Pirchio, Renata S. Auriemma, Alice Vergura, Rosario Pivonello & Annamaria Colao
Pages: 509-522
Published online: 30 Apr 2024
AbstractforInvestigational drugs for the treatment of acromegaly: new agents to transform therapy | Full Text | References | PDF (1.6 MB) | EPUB
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Review Article
Novel carbonic anhydrase inhibitors for the treatment of Helicobacter pylori infection
Claudiu T. Supuran
Pages: 523-532
Published online: 27 Mar 2024
AbstractforNovel carbonic anhydrase inhibitors for the treatment of Helicobacter pylori infection | Full Text | References | PDF (2 MB) | EPUB
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Original Research

Article
Safety, tolerability, and pharmacokinetics of the novel RdRp inhibitor SHEN26 against SARS-CoV-2: a randomized, placebo-controlled, double-blind Phase I study in healthy subjects
Cheng Sun, Hao Liu, Ziwei Ouyang, Jie Ding, Qin Zhang, Hongjie Ma, Dandan Xu, Qian Zhang, Renpeng Zhou, Mingming Yang & Wei Hu
Pages: 533-542
Published online: 30 Apr 2024
AbstractforSafety, tolerability, and pharmacokinetics of the novel RdRp inhibitor SHEN26 against SARS-CoV-2: a randomized, placebo-controlled, double-blind Phase I study in healthy subjects | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
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