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Volume 21, Issue 8

Expert Opinion on Therapeutic Targets

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Cover image for Expert Opinion on Therapeutic Targets, Volume 21, Issue 8, 2017

Expert Opinion on Therapeutic Targets, Volume 21, Issue 8 (2017)

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Expert Opinion on Therapeutic Targets, Volume 21, Issue 8 (2017)

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Editorial

Leucine Rich Repeat Kinase 2: beyond Parkinson’s and beyond kinase inhibitors

Susanna Cogo, Elisa Greggio & Patrick A Lewis

Pages: 751-753

Published online: 22 Jun 2017

First Page PreviewforLeucine Rich Repeat Kinase 2: beyond Parkinson’s and beyond kinase inhibitors | Full Text | References | PDF (354.9 KB)

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Review

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GPER-1/GPR30 a novel estrogen receptor sited in the cell membrane: therapeutic coupling to breast cancer

Luis Molina, Carlos D. Figueroa, Kanti D. Bhoola & Pamela Ehrenfeld

Pages: 755-766

Published online: 12 Jul 2017

AbstractforGPER-1/GPR30 a novel estrogen receptor sited in the cell membrane: therapeutic coupling to breast cancer | Full Text | References | PDF (1.3 MB)

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Review

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer

Jeroen E Guikema, Martine Amiot & Eric Eldering

Pages: 767-779

Published online: 18 Jul 2017

AbstractforExploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer | Full Text | References | PDF (1.3 MB)

5455 Views
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Review

Nrf2: a potential therapeutic target for naturally occurring anticancer drugs?

Elena Catanzaro, Cinzia Calcabrini, Eleonora Turrini, Piero Sestili & Carmela Fimognari

Pages: 781-793

Published online: 10 Jul 2017

AbstractforNrf2: a potential therapeutic target for naturally occurring anticancer drugs? | Full Text | References | PDF (1.2 MB)

497 Views
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Review

Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport

Jinwei Zhang, Jason K. Karimy, Eric Delpire & Kristopher T. Kahle

Pages: 795-804

Published online: 12 Jul 2017

AbstractforPharmacological targeting of SPAK kinase in disorders of impaired epithelial transport | Full Text | References | PDF (1,009.3 KB)

340 Views
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Review

TRAP1: a viable therapeutic target for future cancer treatments?

Giacomo Lettini, Francesca Maddalena, Lorenza Sisinni, Valentina Condelli, Danilo Swann Matassa, Maria Paola Costi, Daniele Simoni, Franca Esposito & Matteo Landriscina

Pages: 805-815

Published online: 18 Jul 2017

AbstractforTRAP1: a viable therapeutic target for future cancer treatments? | Full Text | References | PDF (1.3 MB)

451 Views
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Review

Sleep disturbances and severe stress as glial activators: key targets for treating central sensitization in chronic pain patients?

Jo Nijs, Marco L. Loggia, Andrea Polli, Maarten Moens, Eva Huysmans, Lisa Goudman, Mira Meeus, Luc Vanderweeën, Kelly Ickmans & Daniel Clauw

Pages: 817-826

Published online: 12 Jul 2017

AbstractforSleep disturbances and severe stress as glial activators: key targets for treating central sensitization in chronic pain patients? | Full Text | References | PDF (958.1 KB)

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