Future Medicinal Chemistry, Volume 11, Issue 19 (2019)

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Future Medicinal Chemistry, Volume 11, Issue 19 (2019)

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Editorial

Editorial
Fluorescent RNA Tags: Current and Future Applications
Sven Hennig & Saskia Neubacher
Pages: 2483-2485
Published online: 21 Oct 2019
First Page PreviewforFluorescent RNA Tags: Current and Future Applications | Full Text | References | PDF (183.8 KB) | EPUB
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Free Access

Commentary

Editorial
RNA-Targeted Drug Discovery: Moving Beyond Promiscuous Small-Molecule Scaffolds
Amanda L Garner
Pages: 2487-2490
Published online: 21 Oct 2019
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Research Article

Article
A Structure-Guided Molecular Chaperone Approach for Restoring the Transcriptional Activity of the p53 Cancer Mutant Y220C
Matthias R Bauer, Rhiannon N Jones, Raysa K Tareque, Bradley Springett, Felix A Dingler, Lorena Verduci, Ketan J Patel, Alan R Fersht, Andreas C Joerger & John Spencer
Pages: 2491-2504
Published online: 21 Oct 2019
AbstractforA Structure-Guided Molecular Chaperone Approach for Restoring the Transcriptional Activity of the p53 Cancer Mutant Y220C | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
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Open Access
Article
A Small Cytotoxic Peptide from Frog Elicits Potent Antitumor Immunity to Prevent Local Tumor Growth and Metastases
Xue Qiao, Huaixin Yang, Jiuxiang Gao, Shasha Cai, Nannan Shi, Mengke Wang, Yipeng Wang & Haining Yu
Pages: 2505-2525
Published online: 21 Oct 2019
AbstractforA Small Cytotoxic Peptide from Frog Elicits Potent Antitumor Immunity to Prevent Local Tumor Growth and Metastases | Full Text | References | PDF (10.1 MB) | EPUB | Supplemental
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Article
Thiosemicarbazonate Complexes with Affinity for amyloid-β Fibers: Synthesis, Characterization and Biological Studies
Arantxa Pino-Cuevas, Paula D Raposinho, Célia Fernandes, António Paulo, Ulrich Abram, Rosa Carballo & Ezequiel M Vázquez‐López
Pages: 2527-2546
Published online: 21 Oct 2019
AbstractforThiosemicarbazonate Complexes with Affinity for amyloid-β Fibers: Synthesis, Characterization and Biological Studies | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
High-Affinity Sigma-1 (σ1) Receptor Ligands Based on the σ1 Antagonist PB212
Mauro Niso, Philip D Mosier, Roberta Marottoli, Savina Ferorelli, Giuseppe Cassano, Giuseppe Gasparre, Marcello Leopoldo, Francesco Berardi & Carmen Abate
Pages: 2547-2562
Published online: 21 Oct 2019
AbstractforHigh-Affinity Sigma-1 (σ1) Receptor Ligands Based on the σ1 Antagonist PB212 | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
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Special Report

Review Article
The Prospects of Lipidic Prodrugs: An Old Approach with an Emerging Future
Arik Dahan, Milica Markovic, Aaron Aponick, Ellen M Zimmermann & Shimon Ben-Shabat
Pages: 2563-2571
Published online: 21 Oct 2019
AbstractforThe Prospects of Lipidic Prodrugs: An Old Approach with an Emerging Future | Full Text | References | PDF (309.8 KB) | EPUB
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Review

Review Article
Advances of Proteomics Technologies for Multidrug-Resistant Mechanisms
Tiantian Zhang, Qijuan Yuan, Zhipeng Gu & Changhu Xue
Pages: 2573-2593
Published online: 21 Oct 2019
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Review Article
Current Advances in Idiopathic Pulmonary Fibrosis: The pathogenesis, Therapeutic Strategies and Candidate Molecules
Meng Lv, Yan Liu, Shuli Ma & Zutao Yu
Pages: 2595-2620
Published online: 21 Oct 2019
AbstractforCurrent Advances in Idiopathic Pulmonary Fibrosis: The pathogenesis, Therapeutic Strategies and Candidate Molecules | Full Text | References | PDF (1 MB) | EPUB
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