Future Medicinal Chemistry, Volume 6, Issue 17 (2014)

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Future Medicinal Chemistry, Volume 6, Issue 17 (2014)

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Editorial

Editorial
Enhancing Antibiotic Activity to Combat Resistant Gram-Negative Bacteria: What's Next?
Jean Michel Bolla & Jean Michel Brunel
Pages: 1849-1851
Published online: 15 Dec 2014
First Page PreviewforEnhancing Antibiotic Activity to Combat Resistant Gram-Negative Bacteria: What's Next? | Full Text | References | PDF (915.2 KB)
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Free Access
Editorial
The Potential of 12/15-Lipoxygenase Inhibitors in Stroke Therapy
Klaus van Leyen, Theodore R Holman & David J Maloney
Pages: 1853-1855
Published online: 15 Dec 2014
First Page PreviewforThe Potential of 12/15-Lipoxygenase Inhibitors in Stroke Therapy | Full Text | References | PDF (1.3 MB)
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Preliminary Communication

Brief Report
The Search for a Common Structural Moiety Among Selected Pharmacological Correctors of the Mutant Cftr Chloride Channel
Erika Nieddu, Benedetta Pollarolo, Marco T Mazzei, Maria Anzaldi, Silvia Schenone, Nicoletta Pedemonte, Emanuela Pesce, Luis Jv Galietta & Mauro Mazzei
Pages: 1857-1868
Published online: 15 Dec 2014
AbstractforThe Search for a Common Structural Moiety Among Selected Pharmacological Correctors of the Mutant Cftr Chloride Channel | Full Text | References | PDF (1.5 MB) | Supplemental
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Research Article

Article
Pharmacophore Modeling for Cox-1 and -2 Inhibitors with Ligandscout in Comparison to Discovery Studio
Veronika Temml, Teresa Kaserer, Zsofia Kutil, Premysl Landa, Tomas Vanek & Daniela Schuster
Pages: 1869-1881
Published online: 15 Dec 2014
AbstractforPharmacophore Modeling for Cox-1 and -2 Inhibitors with Ligandscout in Comparison to Discovery Studio | Full Text | References | PDF (1.9 MB) | Supplemental
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Article
Isoxazolotacrines as Non-Toxic and Selective Butyrylcholinesterase Inhibitors for Alzheimer'S Disease
Oussama Cherif, Fatma Allouche, Fakher Chabchoub, Mourad Chioua, Elena Soriano, Matilde Yañez, Ramón Cacabelos, Alejandro Romero, Manuela G López  & Jose Marco-Contelles
Pages: 1883-1891
Published online: 15 Dec 2014
AbstractforIsoxazolotacrines as Non-Toxic and Selective Butyrylcholinesterase Inhibitors for Alzheimer'S Disease | Full Text | References | PDF (1.2 MB) | Supplemental
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Perspective

Review Article
“Too Little, Too Late?” Will Inhibitors of the Hepatitis C Virus P7 Ion Channel Ever Be Used in the Clinic?
Stephen Griffin
Pages: 1893-1907
Published online: 15 Dec 2014
Abstractfor“Too Little, Too Late?” Will Inhibitors of the Hepatitis C Virus P7 Ion Channel Ever Be Used in the Clinic? | Full Text | References | PDF (2.2 MB)
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Review

Review Article
Targeting Sh2 Domains in Breast Cancer
Pietro Morlacchi, Fredika M Robertson, Jim Klostergaard & John S McMurray
Pages: 1909-1926
Published online: 15 Dec 2014
AbstractforTargeting Sh2 Domains in Breast Cancer | Full Text | References | PDF (1.1 MB)
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Review Article
Utilizing Diversity-Oriented Synthesis in Antimicrobial Drug Discovery
Eamon Comer, Jeremy R Duvall & Maurice duPont Lee IV
Pages: 1927-1942
Published online: 15 Dec 2014
AbstractforUtilizing Diversity-Oriented Synthesis in Antimicrobial Drug Discovery | Full Text | References | PDF (1 MB) | Supplemental
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Review Article
Histone Methylases as Novel Drug Targets: Developing Inhibitors of EZH2
Catherine Baugé, Céline Bazille, Nicolas Girard, Eva Lhuissier & Karim Boumediene
Pages: 1943-1965
Published online: 15 Dec 2014
AbstractforHistone Methylases as Novel Drug Targets: Developing Inhibitors of EZH2 | Full Text | References | PDF (1.8 MB) | Supplemental
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Review Article
Mirna-Based Therapies: Strategies and Delivery Platforms for Oligonucleotide and Non-Oligonucleotide Agents
Volker Baumann & Johannes Winkler
Pages: 1967-1984
Published online: 15 Dec 2014
AbstractforMirna-Based Therapies: Strategies and Delivery Platforms for Oligonucleotide and Non-Oligonucleotide Agents | Full Text | References | PDF (1.3 MB)
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