Future Medicinal Chemistry, Volume 7, Issue 4 (2015)

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Future Medicinal Chemistry, Volume 7, Issue 4 (2015)

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Editorial

Editorial
Modifying Natural Antimicrobial Peptides to Generate Bioinspired Antibiotics and Devices
Alinne Pereira de Castro & Octávio Luiz Franco
Pages: 413-415
Published online: 15 Apr 2015
First Page PreviewforModifying Natural Antimicrobial Peptides to Generate Bioinspired Antibiotics and Devices | Full Text | References | PDF (1.3 MB)
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Free Access

Preliminary Communication

Brief Report
New More Polar Symmetrical Bipyridinic Compounds: New Strategy for the Inhibition of Choline Kinase α1
Francisco Fermín Castro-Navas, Santiago Schiaffino-Ortega, María Paz Carrasco-Jimenez, Pablo Ríos-Marco, Carmen Marco, Antonio Espinosa, Miguel Angel Gallo, Elena Mariotto, Giuseppe Basso, Giampietro Viola, Antonio Entrena-Guadix & Luisa Carlota López-Cara
Pages: 417-436
Published online: 15 Apr 2015
AbstractforNew More Polar Symmetrical Bipyridinic Compounds: New Strategy for the Inhibition of Choline Kinase α1 | Full Text | References | PDF (2.7 MB) | Supplemental
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Research Article

Article
Identification of Two Benzopyrroloxazines Acting as Selective GPER Antagonists in Breast Cancer Cells and Cancer-Associated Fibroblasts
Marcello Maggiolini, Maria Francesca Santolla, Silvia Avino, Francesca Aiello, Camillo Rosano, Antonio Garofalo & Fedora Grande
Pages: 437-448
Published online: 15 Apr 2015
AbstractforIdentification of Two Benzopyrroloxazines Acting as Selective GPER Antagonists in Breast Cancer Cells and Cancer-Associated Fibroblasts | Full Text | References | PDF (2.6 MB) | Supplemental
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Article
In Vitro and Ex Vivo Evaluation of Biomaterials' Distinctive Properties as a Result of Thiolation
Flavia Laffleur, Julian Wagner & Arshad Mahmood
Pages: 449-457
Published online: 15 Apr 2015
AbstractforIn Vitro and Ex Vivo Evaluation of Biomaterials' Distinctive Properties as a Result of Thiolation | Full Text | References | PDF (1.3 MB)
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Review

Article
Targeting Bacterial Topoisomerase I to Meet the Challenge of Finding New Antibiotics
Yuk-Ching Tse-Dinh
Pages: 459-471
Published online: 15 Apr 2015
AbstractforTargeting Bacterial Topoisomerase I to Meet the Challenge of Finding New Antibiotics | Full Text | References | PDF (1.3 MB)
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Article
AMPA Receptor-Positive Allosteric Modulators for the Treatment of Schizophrenia: An Overview of Recent Patent Applications
Simon E Ward, Lewis E Pennicott & Paul Beswick
Pages: 473-491
Published online: 15 Apr 2015
AbstractforAMPA Receptor-Positive Allosteric Modulators for the Treatment of Schizophrenia: An Overview of Recent Patent Applications | Full Text | References | PDF (3 MB)
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Article
Biofilm Formation Mechanisms and Targets for Developing Antibiofilm Agents
Nira Rabin, Yue Zheng, Clement Opoku-Temeng, Yixuan Du, Eric Bonsu & Herman O Sintim
Pages: 493-512
Published online: 15 Apr 2015
AbstractforBiofilm Formation Mechanisms and Targets for Developing Antibiofilm Agents | Full Text | References | PDF (6.1 MB)
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Open Access
Article
Challenges and Opportunities Toward Enabling Phenotypic Screening of Complex and 3D Cell Models
Shane R Horman, Christopher Hogan, Karlo Delos Reyes, Frederick Lo & Christophe Antczak
Pages: 513-525
Published online: 15 Apr 2015
AbstractforChallenges and Opportunities Toward Enabling Phenotypic Screening of Complex and 3D Cell Models | Full Text | References | PDF (2 MB)
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Article
Polyfluorinated Groups in Medicinal Chemistry
Marcella Bassetto, Salvatore Ferla & Fabrizio Pertusati
Pages: 527-546
Published online: 15 Apr 2015
AbstractforPolyfluorinated Groups in Medicinal Chemistry | Full Text | References | PDF (2 MB)
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