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Future Medicinal Chemistry
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Volume 7, Issue 6

Future Medicinal Chemistry

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Future Medicinal Chemistry, Volume 7, Issue 6 (2015)

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Future Medicinal Chemistry, Volume 7, Issue 6 (2015)

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Special Focus Issue: Schistosomiasis - Foreword

Schistosomiasis and Its Treatment

Conor R Caffrey

Pages: 675-676

Published online: 21 May 2015

CitationforSchistosomiasis and Its Treatment | Full Text | References | PDF (1 MB)

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Editorial

Praziquantel: Do We Need Another Antischistosoma Treatment?

Alan Fenwick OBE

Pages: 677-680

Published online: 21 May 2015

First Page PreviewforPraziquantel: Do We Need Another Antischistosoma Treatment? | Full Text | References | PDF (980 KB)

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Editorial

Something Old, Something New: is Praziquantel Enough for Schistosomiasis Control?

W Evan Secor & Susan P Montgomery

Pages: 681-684

Published online: 21 May 2015

First Page PreviewforSomething Old, Something New: is Praziquantel Enough for Schistosomiasis Control? | Full Text | References | PDF (1.6 MB)

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Editorial

How Has the Genomics Era Impacted Schistosomiasis Drug Discovery?

Guilherme Oliveira & Raymond J Pierce

Pages: 685-687

Published online: 21 May 2015

First Page PreviewforHow Has the Genomics Era Impacted Schistosomiasis Drug Discovery? | Full Text | References | PDF (1.2 MB)

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Interview

Discussion

Using an Open Source Model to Accelerate Schistosomiasis Drug Research

Matthew H Todd

Pages: 689-692

Published online: 21 May 2015

AbstractforUsing an Open Source Model to Accelerate Schistosomiasis Drug Research | Full Text | References | PDF (978.1 KB)

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Ask the Experts

Discussion

Neglected Tropical Disease Research: Rethinking the Drug Discovery Model

Pages: 693-700

Published online: 21 May 2015

AbstractforNeglected Tropical Disease Research: Rethinking the Drug Discovery Model | Full Text | PDF (1.6 MB)

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Commentary

Editorial

What is the Mechanism of Action of Praziquantel and How Might Resistance Strike?

Pauline M Cupit & Charles Cunningham

Pages: 701-705

Published online: 21 May 2015

First Page PreviewforWhat is the Mechanism of Action of Praziquantel and How Might Resistance Strike? | Full Text | References | PDF (1.2 MB)

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Editorial

Repurposing Apoptosis-Inducing Cancer Drugs to Treat Schistosomiasis

Erinna F Lee & Walter Douglas Fairlie

Pages: 707-711

Published online: 21 May 2015

First Page PreviewforRepurposing Apoptosis-Inducing Cancer Drugs to Treat Schistosomiasis | Full Text | References | PDF (1.4 MB)

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Preliminary Communication

Brief Report

Design, Synthesis and Biological Evaluation of Praziquantel and Endoperoxide Conjugates as Antischistosomal Agents

Jing-jing Yang, Jerome Boissier, Jing-Lei Chen, Houzong Yao, Shilin Yang, Anne Rognon & Chunhua Qiao

Pages: 713-725

Published online: 21 May 2015

AbstractforDesign, Synthesis and Biological Evaluation of Praziquantel and Endoperoxide Conjugates as Antischistosomal Agents | Full Text | References | PDF (1.2 MB)

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Special Report

Article

Repurposing Pharma Assets: An Accelerated Mechanism for Strengthening the Schistosomiasis Drug Development Pipeline

Roopa Ramamoorthi, Katy M Graef & Jennifer Dent

Pages: 727-735

Published online: 21 May 2015

AbstractforRepurposing Pharma Assets: An Accelerated Mechanism for Strengthening the Schistosomiasis Drug Development Pipeline | Full Text | References | PDF (893.3 KB) | Supplemental

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Review

Article

Re-Positioning Protein-Kinase Inhibitors Against Schistosomiasis

Verena Gelmedin, Colette Dissous & Christoph G Grevelding

Pages: 737-752

Published online: 21 May 2015

AbstractforRe-Positioning Protein-Kinase Inhibitors Against Schistosomiasis | Full Text | References | PDF (1.3 MB)

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Article

Target-Based Molecular Modeling Strategies for Schistosomiasis Drug Discovery

Leonardo G Ferreira, Glaucius Oliva & Adriano D Andricopulo

Pages: 753-764

Published online: 21 May 2015

AbstractforTarget-Based Molecular Modeling Strategies for Schistosomiasis Drug Discovery | Full Text | References | PDF (2.6 MB)

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Article

Schistosome Sirtuins as Drug Targets

Julien Lancelot, Alejandro Cabezas-Cruz, Stéphanie Caby, Martin Marek, Johan Schultz, Christophe Romier, Wolfgang Sippl, Manfred Jung & Raymond J Pierce

Pages: 765-782

Published online: 21 May 2015

AbstractforSchistosome Sirtuins as Drug Targets | Full Text | References | PDF (2.1 MB)

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Article

Drugging the Schistosome Zinc-Dependent HDACs: Current Progress and Future Perspectives

Martin Marek, Guilherme Oliveira, Raymond J Pierce, Manfred Jung, Wolfgang Sippl & Christophe Romier

Pages: 783-800

Published online: 21 May 2015

AbstractforDrugging the Schistosome Zinc-Dependent HDACs: Current Progress and Future Perspectives | Full Text | References | PDF (8.8 MB)

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Article

Natural Products with Antischistosomal Activity

Josué de Moraes

Pages: 801-820

Published online: 21 May 2015

AbstractforNatural Products with Antischistosomal Activity | Full Text | References | PDF (1.3 MB)

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Article

Toward Organometallic Antischistosomal Drug Candidates

Jeannine Hess, Jennifer Keiser & Gilles Gasser

Pages: 821-830

Published online: 21 May 2015

AbstractforToward Organometallic Antischistosomal Drug Candidates | Full Text | References | PDF (1.2 MB)

1981 Views
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Future Medicinal Chemistry (Vol.7, Iss.6, 2015)

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