Immunological Investigations, Volume 51, Issue 6 (2022)

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Immunological Investigations, Volume 51, Issue 6 (2022)

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Research Article

Article
Circ_0128846/miR-140-3p/JAK2 Network in Osteoarthritis Development
Hongjun Li, Zhongyu Liu, Xiaoyun Guo & Mei Zhang
Pages: 1529-1547
Published online: 21 Sep 2021
AbstractforCirc_0128846/miR-140-3p/JAK2 Network in Osteoarthritis Development | Full Text | References | PDF (10.9 MB) | EPUB
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Article
Ankylosing Spondylitis Patients Display Aberrant ERAP1 Gene DNA Methylation and Expression
Yubo Ma, Dazhi Fan, Shanshan Xu, Jixiang Deng, Xing Gao, Shiyang Guan, Xu Zhang & Faming Pan
Pages: 1548-1560
Published online: 24 Sep 2021
AbstractforAnkylosing Spondylitis Patients Display Aberrant ERAP1 Gene DNA Methylation and Expression | Full Text | References | PDF (968.6 KB) | EPUB
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Article
Epicutaneous Administration of 17β-Estradiol Induces Langerhans Cells Depletion
Katia Jarquín-Yáñez, Miguel Ángel Herrera-Enriquez, Cristina Lemini, Edith Melendez-Moreno, Paulina Villena-López, Maria Estela Ávila, Beatriz Hernández-Téllez, Gabriela Piñón-Zárate, Enrique Agustin Sampedro-Carrillo & Andrés Eliú Castell-Rodríguez
Pages: 1561-1581
Published online: 27 Sep 2021
AbstractforEpicutaneous Administration of 17β-Estradiol Induces Langerhans Cells Depletion | Full Text | References | PDF (4 MB) | EPUB
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Article
CYT387 Inhibits the Hyperproliferative Potential of Fibroblast-like Synoviocytes via Modulation of IL-6/JAK1/STAT3 Signaling in Rheumatoid Arthritis
Susmita Srivastava, Snigdha Samarpita, Ramamoorthi Ganesan & Mahaboobkhan Rasool
Pages: 1582-1597
Published online: 27 Oct 2021
AbstractforCYT387 Inhibits the Hyperproliferative Potential of Fibroblast-like Synoviocytes via Modulation of IL-6/JAK1/STAT3 Signaling in Rheumatoid Arthritis | Full Text | References | PDF (5.3 MB) | EPUB
  • 336 Views
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Article
Circ_0008365 Suppresses Apoptosis, Inflammation and Extracellular Matrix Degradation of IL-1β-treated Chondrocytes in Osteoarthritis by Regulating miR-324-5p/BMPR2/NF-κB Signaling Axis
Zilong Zhang, Teng Zhao, Haiwei Xu & Xing Wu
Pages: 1598-1611
Published online: 17 Feb 2022
AbstractforCirc_0008365 Suppresses Apoptosis, Inflammation and Extracellular Matrix Degradation of IL-1β-treated Chondrocytes in Osteoarthritis by Regulating miR-324-5p/BMPR2/NF-κB Signaling Axis | Full Text | References | PDF (6 MB) | EPUB | Supplemental
  • 172 Views
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Article
Reciprocal SH2-SH3 Domain Contacts between ITK Molecules Limit T Cell Receptor Signaling in Th2-type CD4+ T Cells
Ji-Long Chen, Jennifer Y. Barr, Jonathan J. Zuk, Jacob V. Gorman & John D. Colgan
Pages: 1612-1629
Published online: 29 Nov 2021
AbstractforReciprocal SH2-SH3 Domain Contacts between ITK Molecules Limit T Cell Receptor Signaling in Th2-type CD4+ T Cells | Full Text | References | PDF (2.4 MB) | EPUB
  • 138 Views
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Article
Vitamin D decreases cell death and inflammation in human umbilical vein endothelial cells and placental explants from pregnant women with preeclampsia cultured with TNF-α
Priscila Rezeck Nunes, Mariana Romao-Veiga, Vanessa Rocha Ribeiro, Larissa Ragozo Cardoso de Oliveira, Thiago Gameiro Zupelli, Joelcio Francisco Abbade, Jose Carlos Peracoli & Maria Terezinha Serrao Peracoli
Pages: 1630-1646
Published online: 22 Dec 2021
AbstractforVitamin D decreases cell death and inflammation in human umbilical vein endothelial cells and placental explants from pregnant women with preeclampsia cultured with TNF-α | Full Text | References | PDF (2.3 MB) | EPUB
  • 216 Views
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Article
MicroRNA Expression in Neonates with Late-onset Sepsis – A Cross-sectional Comparative Study
Saranya Sankar, Kathirvel Maruthai, Zachariah Bobby & Bethou Adhisivam
Pages: 1647-1659
Published online: 14 Jan 2022
AbstractforMicroRNA Expression in Neonates with Late-onset Sepsis – A Cross-sectional Comparative Study | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 174 Views
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Article
Circ_0020093 Overexpression Alleviates Interleukin-1 Beta-induced Inflammation, Apoptosis and Extracellular Matrix Degradation in Human Chondrocytes by Targeting the miR-181a-5p/ERG Pathway
Jun Zhu & Yongchun Guo
Pages: 1660-1677
Published online: 11 Jan 2022
AbstractforCirc_0020093 Overexpression Alleviates Interleukin-1 Beta-induced Inflammation, Apoptosis and Extracellular Matrix Degradation in Human Chondrocytes by Targeting the miR-181a-5p/ERG Pathway | Full Text | References | PDF (9.8 MB) | EPUB | Supplemental
  • 138 Views
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Article
PCSK9 Suppresses M2-Like Tumor-Associated Macrophage Polarization by Regulating the Secretion of OX40L from Hepatocellular Carcinoma Cells
Jing Hu, Meixia Zhang, Ling Gui, Qinsi Wan, Jiawei Zhong, Liangliang Bai & Mingyan He
Pages: 1678-1693
Published online: 25 Jan 2022
AbstractforPCSK9 Suppresses M2-Like Tumor-Associated Macrophage Polarization by Regulating the Secretion of OX40L from Hepatocellular Carcinoma Cells | Full Text | References | PDF (9.9 MB) | EPUB
  • 411 Views
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Article
MicroRNA-30a Targets Notch1 to Alleviate Podocyte Injury in Lupus Nephritis
Aoyang Guo, Yadi Sun, Xiaona Xu & Qian Xing
Pages: 1694-1706
Published online: 13 Jan 2022
AbstractforMicroRNA-30a Targets Notch1 to Alleviate Podocyte Injury in Lupus Nephritis | Full Text | References | PDF (1.1 MB) | EPUB
  • 158 Views
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Article
Knockdown of circRNA Paralemmin 2 Ameliorates Lipopolysaccharide-induced Murine Lung Epithelial Cell Injury by Sponging miR-330-5p to Reduce ROCK2 Expression
Yi Ren, Liang Li, Mengmeng Wang, Zhizhou Yang, Zhaorui Sun, Wei Zhang, Liping Cao & Shinan Nie
Pages: 1707-1724
Published online: 16 Feb 2022
AbstractforKnockdown of circRNA Paralemmin 2 Ameliorates Lipopolysaccharide-induced Murine Lung Epithelial Cell Injury by Sponging miR-330-5p to Reduce ROCK2 Expression | Full Text | References | PDF (8.9 MB) | EPUB
  • 185 Views
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Review

Review
Scavenger Receptor A1 Signaling Pathways Affecting Macrophage Functions in Innate and Adaptive Immunity
Elizabeth Linares-Alcántara & Fela Mendlovic
Pages: 1725-1755
Published online: 05 Jan 2022
AbstractforScavenger Receptor A1 Signaling Pathways Affecting Macrophage Functions in Innate and Adaptive Immunity | Full Text | References | PDF (5.8 MB) | EPUB
  • 445 Views
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Review
Mitochondrial DNA as a Possible Ligand for TLR9 in Irinotecan-induced Small Intestinal Mucositis
Thiago Vinicius Ávila, Zélia Menezes-Garcia, Raquel Duque do Nascimento Arifa, Frederico Marianetti Soriani, Alexandre de Magalhães Vieira Machado, Mauro Martins Teixeira, Caio Tavares Fagundes & Daniele G. Souza
Pages: 1756-1771
Published online: 14 Feb 2022
AbstractforMitochondrial DNA as a Possible Ligand for TLR9 in Irinotecan-induced Small Intestinal Mucositis | Full Text | References | PDF (3 MB) | EPUB
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Research Article

Article
Association between Psoriasis Disease and IFN-λ Gene Polymorphisms
Büşra Yilmaz, Güneş Çakmak Genç, Sevim Karakaş Çelik, Nilgün Solak Tekin, Murat Can & Ahmet Dursun
Pages: 1772-1784
Published online: 04 Feb 2022
AbstractforAssociation between Psoriasis Disease and IFN-λ Gene Polymorphisms | Full Text | References | PDF (628.5 KB) | EPUB
  • 243 Views
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Article
Mesenchymal Stem Cells-derived Exosomes Ameliorate Lupus by Inducing M2 Macrophage Polarization and Regulatory T Cell Expansion in MRL/lpr Mice
Wenchang Sun, Shushan Yan, Chunjuan Yang, Jinghan Yang, Hui Wang, Chaoran Li, Lili Zhang, Lu Zhao, Jiaojiao Zhang, Min Cheng, Xiangling Li & Donghua Xu
Pages: 1785-1803
Published online: 25 Mar 2022
AbstractforMesenchymal Stem Cells-derived Exosomes Ameliorate Lupus by Inducing M2 Macrophage Polarization and Regulatory T Cell Expansion in MRL/lpr Mice | Full Text | References | PDF (6.9 MB) | EPUB
  • 1295 Views
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Article
Cytotoxic T Lymphocytes Expressing GPR56 are Up-regulated in the Peripheral Blood of Patients with Active Rheumatoid Arthritis and Reflect Disease Progression
Xingyue Zeng, Mohan Zheng, Tianci Liu, Ayibaota Bahabayi, Shi Song, Xiayidan Alimu, Rui Kang, Songsong Lu, Ying Song & Chen Liu
Pages: 1804-1819
Published online: 11 Apr 2022
AbstractforCytotoxic T Lymphocytes Expressing GPR56 are Up-regulated in the Peripheral Blood of Patients with Active Rheumatoid Arthritis and Reflect Disease Progression | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 324 Views
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Article
The Association of Angiopoietin-2 1064 C/T Rs3020221 Gene Polymorphism with Knee Osteoarthritis
Hanan H. Omar, Samah I. Nasef & Maha M. Anani
Pages: 1820-1832
Published online: 06 Apr 2022
AbstractforThe Association of Angiopoietin-2 1064 C/T Rs3020221 Gene Polymorphism with Knee Osteoarthritis | Full Text | References | PDF (861.3 KB) | EPUB
  • 110 Views
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Article
The Effect of CD226 on the Balance between Inflammatory Monocytes and Small Peritoneal Macrophages in Mouse Ulcerative Colitis
Juan Li, Feng Zhao, Qi Qin, Liu Yang, Yuan Jiang, Yongli Hou, Yazhen Wang, Wenjing Zhou, Liang Fang & Lihua Chen
Pages: 1833-1842
Published online: 25 Apr 2022
AbstractforThe Effect of CD226 on the Balance between Inflammatory Monocytes and Small Peritoneal Macrophages in Mouse Ulcerative Colitis | Full Text | References | PDF (4.6 MB) | EPUB
  • 246 Views
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Article
A Preventive Role of RANTES Genetic Variation against Undifferentiated Schizophrenia
Hana Saoud, Amira Ben Afia, Youssef Aflouk, Lotfi Gaha & Besma Bel Hadj Jrad
Pages: 1843-1855
Published online: 27 Apr 2022
AbstractforA Preventive Role of RANTES Genetic Variation against Undifferentiated Schizophrenia | Full Text | References | PDF (524.7 KB) | EPUB
  • 83 Views
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Article
Prognostic Value of Serum MICA Levels as a Marker of Severity in COVID-19 Patients
Faramarz Farzad, Neda Yaghoubi, Farahzad Jabbari-Azad, Mahmoud Mahmoudi & Mojgan Mohammadi
Pages: 1856-1866
Published online: 28 Apr 2022
AbstractforPrognostic Value of Serum MICA Levels as a Marker of Severity in COVID-19 Patients | Full Text | References | PDF (737.5 KB) | EPUB
  • 76 Views
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Article
Lack of Association Between PDCD-1 Polymorphisms and Colorectal Cancer Risk: A Case-Control Study
Jing Lin, Hanshen Chen, Yufang Huang, Weifeng Tang, Sheng Zhang & Yu Chen
Pages: 1867-1882
Published online: 02 May 2022
AbstractforLack of Association Between PDCD-1 Polymorphisms and Colorectal Cancer Risk: A Case-Control Study | Full Text | References | PDF (399.3 KB) | EPUB
  • 992 Views
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Open Access
Article
Recurrent Infections and Immunodeficiency Caused by Severe Pancytopenia Associated with a Novel Life-Threatening Mutation in Hypoxia-Upregulated Protein 1
Hossein Jafari Khamirani, Mehdi Dianatpour, Sina Zoghi, Sanaz Mohammadi, Ashkan Habib, Seyed Alireza Dastgheib, Seyed Mohammad Bagher Tabei, Mohadeseh Molayemat & Babak Shirazi Yeganeh
Pages: 1883-1894
Published online: 12 May 2022
AbstractforRecurrent Infections and Immunodeficiency Caused by Severe Pancytopenia Associated with a Novel Life-Threatening Mutation in Hypoxia-Upregulated Protein 1 | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 215 Views
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Article
Interleukin-18 Inhibition Protects Against Intervertebral Disc Degeneration via the Inactivation of Caspase-3/9 Dependent Apoptotic Pathways
Kai Zhang, Lei Gao, Hai-xu Wang, Lei Ye, Yan-yan Shi, Wu-yan Yang, Ya-nan Li & Yan Li
Pages: 1895-1907
Published online: 03 Aug 2022
AbstractforInterleukin-18 Inhibition Protects Against Intervertebral Disc Degeneration via the Inactivation of Caspase-3/9 Dependent Apoptotic Pathways | Full Text | References | PDF (4.9 MB) | EPUB
  • 127 Views
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Article
The Impact of STAT3 rs1053005 Variation on Type 1 Diabetes Mellitus Susceptibility: Association Study and in Silico Analysis
Maryam Zandi, Vaha Akbary Moghaddam, Zivar Salehi, Farhad Mashayekhi & Setila Dalili
Pages: 1908-1919
Published online: 28 Jun 2022
AbstractforThe Impact of STAT3 rs1053005 Variation on Type 1 Diabetes Mellitus Susceptibility: Association Study and in Silico Analysis | Full Text | References | PDF (1.3 MB) | EPUB
  • 201 Views
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Correction

Correction
Correction
Page: 1920
Published online: 04 Aug 2020
CitationforCorrection | Full Text | PDF (163.4 KB) | EPUB
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