Pharmaceutical Development and Technology, Volume 26, Issue 1 (2021)

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Pharmaceutical Development and Technology, Volume 26, Issue 1 (2021)

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Research Articles

Article
Co-administration of paclitaxel and 2-methoxyestradiol using folate-conjugated human serum albumin nanoparticles for improving drug resistance and antitumor efficacy
Xinyang Liu, Taoqian Zhao, Yue Xu, Pengchao Huo, Xia Xu, Zhenzhong Zhang, Qingfeng Tian & Nan Zhang
Pages: 1-10
Published online: 06 Oct 2020
AbstractforCo-administration of paclitaxel and 2-methoxyestradiol using folate-conjugated human serum albumin nanoparticles for improving drug resistance and antitumor efficacy | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 150 Views
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Article
Developability assessment for monoclonal antibody drug candidates: a case study
Vivek Kumar Garripelli, Zhen Wu & Supriya Gupta
Pages: 11-20
Published online: 14 Oct 2020
AbstractforDevelopability assessment for monoclonal antibody drug candidates: a case study | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 779 Views
  • 10 CrossRef citations
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Article
Mitochondrial targeted doxorubicin derivatives delivered by ROS-responsive nanocarriers to breast tumor for overcoming of multidrug resistance
Xin-Cheng Zhong, Ming-Han Shi, Hui-Na Liu, Jie-Jian Chen, Tian-Tian Wang, Meng-Ting Lin, Zhen-Tao Zhang, Yi Zhou, Yi-Ying Lu, Wen-Hong Xu, Jian-Qing Gao, Dong-Hang Xu, Min Han & Yi-Ding Chen
Pages: 21-29
Published online: 18 Oct 2020
AbstractforMitochondrial targeted doxorubicin derivatives delivered by ROS-responsive nanocarriers to breast tumor for overcoming of multidrug resistance | Full Text | References | PDF (2 MB) | EPUB
  • 167 Views
  • 4 CrossRef citations
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Article
Nanoparticles integrating natural and synthetic polymers for in vivo insulin delivery
Safy Hadiya, Radwa Radwan, Menna Zakaria, Tahra El-Sherif, Mostafa A. Hamad & Mahmoud Elsabahy
Pages: 30-40
Published online: 09 Oct 2020
AbstractforNanoparticles integrating natural and synthetic polymers for in vivo insulin delivery | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 256 Views
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Article
Effect of coating excipients on chemical stability of active coated tablets
Umesh Kestur, Divyakant Desai, Zhixin Zong, Anuji Abraham & John Fiske
Pages: 41-47
Published online: 14 Oct 2020
AbstractforEffect of coating excipients on chemical stability of active coated tablets | Full Text | References | PDF (1.1 MB) | EPUB
  • 298 Views
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Article
Multivariate analysis in the development of bioequivalent tablets containing bicalutamide
Roman Goněc, Aleš Franc, Petr Doležel, Pavel Farkaš & Petr Sova
Pages: 48-59
Published online: 12 Nov 2020
AbstractforMultivariate analysis in the development of bioequivalent tablets containing bicalutamide | Full Text | References | PDF (1.9 MB) | EPUB
  • 98 Views
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Article
Supersaturable self-microemulsifying drug delivery system enhances dissolution and bioavailability of telmisartan
Sun Young Park, Chang Hwa Jin, Yoon Tae Goo, Bo Ram Chae, Ho Yub Yoon, Chang Hyun Kim, Seh Hyon Song, Sang Beom Han & Young Wook Choi
Pages: 60-68
Published online: 18 Oct 2020
AbstractforSupersaturable self-microemulsifying drug delivery system enhances dissolution and bioavailability of telmisartan | Full Text | References | PDF (1.1 MB) | EPUB
  • 182 Views
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Article
Optimized piperine–phospholipid complex with enhanced bioavailability and hepatoprotective activity
Sayan Biswas, Pulok K. Mukherjee, Amit Kar, Subhadip Bannerjee, Rawiwan Charoensub & Thidarat Duangyod
Pages: 69-80
Published online: 19 Oct 2020
AbstractforOptimized piperine–phospholipid complex with enhanced bioavailability and hepatoprotective activity | Full Text | References | PDF (2.2 MB) | EPUB
  • 171 Views
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Article
Novel biomimetic nanostructured lipid carriers for cancer therapy: preparation, characterization, and in vitro/in vivo evaluation
Jianwen Zhou, Biru Guo, Wenquan Zhu, Xiaoyu Sui, Xiaoxing Ma, Jiayi Qian, Lixin Cao & Cuiyan Han
Pages: 81-91
Published online: 21 Oct 2020
AbstractforNovel biomimetic nanostructured lipid carriers for cancer therapy: preparation, characterization, and in vitro/in vivo evaluation | Full Text | References | PDF (2.5 MB) | EPUB
  • 140 Views
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Article
Physicochemical, pharmacokinetic, and pharmacodynamic characterization of isradipine tablets for controlled release
D. Nagasamy Venkatesh, S. N. Meyyanathan, R. Shanmugam, S. S. Kamatham, J. R. Campos, J. Dias-Ferreira, E. Sanchez-Lopez, J. C. Cardoso, P. Severino & E. B. Souto
Pages: 92-100
Published online: 03 Nov 2020
AbstractforPhysicochemical, pharmacokinetic, and pharmacodynamic characterization of isradipine tablets for controlled release | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 146 Views
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Article
Profiling gene expression dynamics underpinning conventional testing approaches to better inform pre-clinical evaluation of an age appropriate spironolactone formulation
Craig Russell, Majad Hussain, David Huen, Ayesha S. Rahman & Afzal R. Mohammed
Pages: 101-109
Published online: 01 Nov 2020
AbstractforProfiling gene expression dynamics underpinning conventional testing approaches to better inform pre-clinical evaluation of an age appropriate spironolactone formulation | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 90 Views
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Article
Evaluation of antitumor efficacy of folate-poly(2-ethyl-2-oxazoline)-distearoyl phosphatidyl ethanolamine based liposome
Xiaowei Wang, Yunfei Li, Dan Wang, Xuelei Wang, Wei Yuan, Wuli Zhao & Guimin Xia
Pages: 110-118
Published online: 03 Nov 2020
AbstractforEvaluation of antitumor efficacy of folate-poly(2-ethyl-2-oxazoline)-distearoyl phosphatidyl ethanolamine based liposome | Full Text | References | PDF (2.1 MB) | EPUB
  • 233 Views
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