International Journal of Radiation Biology, Volume 98, Issue 12 (2022)

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International Journal of Radiation Biology, Volume 98, Issue 12 (2022)

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Adverse Outcome Pathways in Radiation Protection

Editorial

Editorial
Introduction to the special issue on adverse outcome pathways in radiation protection
Vinita Chauhan, Omid Azimzadeh, Sisko Salomaa & Nobuyuki Hamada
Pages: 1691-1693
Published online: 26 Sep 2022
First Page PreviewforIntroduction to the special issue on adverse outcome pathways in radiation protection | Full Text | References | PDF (711.8 KB) | EPUB
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Commentary

Article Commentary
Adverse outcome pathway: a path toward better data consolidation and global co-ordination of radiation research
Vinita Chauhan, Danielle Beaton, Nobuyuki Hamada, Ruth Wilkins, Julie Burtt, Julie Leblanc, Donald Cool, Jacqueline Garnier-Laplace, Dominique Laurier, Yevgeniya Le, Yukata Yamada & Knut Erik Tollefsen
Pages: 1694-1703
Published online: 07 Jan 2022
AbstractforAdverse outcome pathway: a path toward better data consolidation and global co-ordination of radiation research | Full Text | References | PDF (2.1 MB) | EPUB
  • 1571 Views
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Open Access

Reviews

Review
A high-level overview of the OECD AOP Development Programme
Vinita Chauhan, Nobuyuki Hamada, Ruth Wilkins, Jacqueline Garnier-Laplace, Dominique Laurier, Danielle Beaton & Knut Erik Tollefsen
Pages: 1704-1713
Published online: 24 Aug 2022
AbstractforA high-level overview of the OECD AOP Development Programme | Full Text | References | PDF (1.8 MB) | EPUB
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Review
Establishing a communication and engagement strategy to facilitate the adoption of the adverse outcome pathways in radiation research and regulation
Vinita Chauhan, Nobuyuki Hamada, Jacqueline Garnier-Laplace, Dominique Laurier, Danielle Beaton, Knut Erik Tollefsen & Paul A. Locke
Pages: 1714-1721
Published online: 20 Jul 2022
AbstractforEstablishing a communication and engagement strategy to facilitate the adoption of the adverse outcome pathways in radiation research and regulation | Full Text | References | PDF (1.5 MB) | EPUB
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Open Access
Review
Application of radiation omics in the development of adverse outcome pathway networks: an example of radiation-induced cardiovascular disease
Omid Azimzadeh, Simone Moertl, Raghda Ramadan, Bjorn Baselet, Evagelia C. Laiakis, Soji Sebastian, Danielle Beaton, Jaana M. Hartikainen, Jan Christian Kaiser, Afshin Beheshti, Sisko Salomaa, Vinita Chauhan & Nobuyuki Hamada
Pages: 1722-1751
Published online: 24 Aug 2022
AbstractforApplication of radiation omics in the development of adverse outcome pathway networks: an example of radiation-induced cardiovascular disease | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Review
Development of an adverse outcome pathway for radiation-induced microcephaly via expert consultation and machine learning
Thomas Jaylet, Roel Quintens, Mohamed Abderrafi Benotmane, Jukka Luukkonen, Ignacia Braga Tanaka III, Chrystelle Ibanez, Christelle Durand, Magdalini Sachana, Omid Azimzadeh, Christelle Adam-Guillermin, Knut Erik Tollefsen, Olivier Laurent, Karine Audouze & Olivier Armant
Pages: 1752-1762
Published online: 18 Aug 2022
AbstractforDevelopment of an adverse outcome pathway for radiation-induced microcephaly via expert consultation and machine learning | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Original Articles

Article
Radiation adverse outcome pathways (AOPs) are on the horizon: advancing radiation protection through an international Horizon-Style exercise
Julie J. Burtt, Julie Leblanc, Kristi Randhawa, Addie Ivanova, Murray A. Rudd, Ruth Wilkins, Edouard I. Azzam, Markus Hecker, Nele Horemans, Hildegarde Vandenhove, Christelle Adam-Guillermin, Olivier Armant, Dmitry Klokov, Karine Audouze, Jan Christian Kaiser, Simone Moertl, Katalin Lumniczky, Ignacia B. Tanaka III, Yutaka Yamada, Nobuyuki Hamada, Isaf Al-Nabulsi, R. Julian Preston, Simon Bouffler, Kimberly Applegate, Donald Cool, Danielle Beaton, Knut Erik Tollefsen, Jacqueline Garnier-Laplace, Dominique Laurier & Vinita Chauhan
Pages: 1763-1776
Published online: 26 Sep 2022
AbstractforRadiation adverse outcome pathways (AOPs) are on the horizon: advancing radiation protection through an international Horizon-Style exercise | Full Text | References | PDF (5.6 MB) | EPUB | Supplemental
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Article
Deploying elements of scoping review methods for adverse outcome pathway development: a space travel case example
Tatiana Kozbenko, Nadine Adam, Vita Lai, Snehpal Sandhu, Jacqueline Kuan, Danicia Flores, Meghan Appleby, Hanna Parker, Robyn Hocking, Katya Tsaioun, Carole Yauk, Ruth Wilkins & Vinita Chauhan
Pages: 1777-1788
Published online: 22 Aug 2022
AbstractforDeploying elements of scoping review methods for adverse outcome pathway development: a space travel case example | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
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Open Access
Article
Adverse outcome pathways and linkages to transcriptomic effects relevant to ionizing radiation injury
Jihang Yu, Wangshu Tu, Andrea Payne, Chris Rudyk, Sarita Cuadros Sanchez, Saadia Khilji, Premkumari Kumarathasan, Sanjeena Subedi, Brittany Haley, Alicia Wong, Catalina Anghel, Yi Wang & Vinita Chauhan
Pages: 1789-1801
Published online: 22 Aug 2022
AbstractforAdverse outcome pathways and linkages to transcriptomic effects relevant to ionizing radiation injury | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 744 Views
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Article
International expert group collaboration for developing an adverse outcome pathway for radiation induced leukemia
Dmitry Klokov, Kimberly Applegate, Christophe Badie, Dag Anders Brede, Fieke Dekkers, Melis Karabulutoglu, Yevgeniya Le, Eric Andreas Rutten, Katalin Lumniczky & Maria Gomolka
Pages: 1802-1815
Published online: 07 Sep 2022
AbstractforInternational expert group collaboration for developing an adverse outcome pathway for radiation induced leukemia | Full Text | References | PDF (1.6 MB) | EPUB
  • 1455 Views
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Open Access
Article
Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Knut Erik Tollefsen, Frédéric Alonzo, Nicholas A. Beresford, Dag Anders Brede, Elizabeth Dufourcq-Sekatcheff, Rodolphe Gilbin, Nele Horemans, Selma Hurem, Patrick Laloi, Erica Maremonti, Deborah Oughton, Olivier Simon, You Song, Michael D. Wood, Li Xie & Sandrine Frelon
Pages: 1816-1831
Published online: 19 Aug 2022
AbstractforAdverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1856 Views
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Article
Benchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research
Robert Stainforth, Ngoc Vuong, Nadine Adam, Byron Kuo, Ruth C. Wilkins, Carole Yauk, Afshin Beheshti & Vinita Chauhan
Pages: 1832-1844
Published online: 22 Aug 2022
AbstractforBenchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 789 Views
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Article
Evaluating the influences of confounding variables on benchmark dose using a case study in the field of ionizing radiation
Nadine Adam, Ngoc Q. Vuong, Hailey Adams, Byron Kuo, Afshin Beheshti, Carole Yauk, Ruth Wilkins & Vinita Chauhan
Pages: 1845-1855
Published online: 23 Aug 2022
AbstractforEvaluating the influences of confounding variables on benchmark dose using a case study in the field of ionizing radiation | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 448 Views
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