Journal of Receptors and Signal Transduction, Volume 40, Issue 6 (2020)

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Journal of Receptors and Signal Transduction, Volume 40, Issue 6 (2020)

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Review Article

Article
FOXF1 ameliorates angiotensin II-induced cardiac fibrosis in cardiac fibroblasts through inhibiting the TGF-β1/Smad3 signaling pathway
Daoxin Jin & Fangfang Han
Pages: 493-500
Published online: 04 Jun 2020
AbstractforFOXF1 ameliorates angiotensin II-induced cardiac fibrosis in cardiac fibroblasts through inhibiting the TGF-β1/Smad3 signaling pathway | Full Text | References | PDF (2.5 MB) | EPUB
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Original Articles

Article
Quantitative structure-activity relationship (QSAR) and design of novel ligands that demonstrate high potency and target selectivity as protein tyrosine phosphatase 1B (PTP 1B) inhibitors as an effective strategy used to model anti-diabetic agents
David Ebuka Arthur, Stephen Ejeh & Adamu Uzairu
Pages: 501-520
Published online: 12 May 2020
AbstractforQuantitative structure-activity relationship (QSAR) and design of novel ligands that demonstrate high potency and target selectivity as protein tyrosine phosphatase 1B (PTP 1B) inhibitors as an effective strategy used to model anti-diabetic agents | Full Text | References | PDF (4.4 MB) | EPUB
  • 135 Views
  • 15 CrossRef citations
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Article
The potential protective roles of zinc, selenium and glutathione on hypoxia-induced TRPM2 channel activation in transfected HEK293 cells
Dilek Duzgun Ergun, Sefik Dursun, Nural Pastaci Ozsobaci, Ozden Hatırnaz Ng, Mustafa Naziroglu & Dervis Ozcelik
Pages: 521-530
Published online: 30 Apr 2020
AbstractforThe potential protective roles of zinc, selenium and glutathione on hypoxia-induced TRPM2 channel activation in transfected HEK293 cells | Full Text | References | PDF (1.8 MB) | EPUB
  • 380 Views
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Article
Amyloid beta (1–42) downregulates adenosine-2b receptors in addition to mitochondrial impairment and cholinergic dysfunction in memory-sensitive mouse brain regions
Bhupesh Chandra Semwal & Debapriya Garabadu
Pages: 531-540
Published online: 04 Jun 2020
AbstractforAmyloid beta (1–42) downregulates adenosine-2b receptors in addition to mitochondrial impairment and cholinergic dysfunction in memory-sensitive mouse brain regions | Full Text | References | PDF (2.1 MB) | EPUB
  • 144 Views
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Article
Curcumin potentiates laryngeal squamous carcinoma radiosensitivity via NF-ΚB inhibition by suppressing IKKγ expression
Xin-zhou Deng, Shan-shan Geng, Ming Luo, Jing-jing Chai, Ying Xu, Chun-li Chen, Li Qiu, Qing Ke, Qi-wen Duan, Shi-mao Song, Li Shen & Zhi-guo Luo
Pages: 541-549
Published online: 09 Jun 2020
AbstractforCurcumin potentiates laryngeal squamous carcinoma radiosensitivity via NF-ΚB inhibition by suppressing IKKγ expression | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 107 Views
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Article
Antagonizing effect of icaritin on apoptosis and injury of hippocampal neurocytes induced by amyloid beta via GR/BDNF signaling pathway
Congfeng Tang, Xuejiao Liu, Hailing Zhu & Quan Lu
Pages: 550-559
Published online: 01 Jun 2020
AbstractforAntagonizing effect of icaritin on apoptosis and injury of hippocampal neurocytes induced by amyloid beta via GR/BDNF signaling pathway | Full Text | References | PDF (2.2 MB) | EPUB
  • 172 Views
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Article
Citrate pretreatment attenuates hypoxia/reoxygenation-induced cardiomyocyte injury via regulating microRNA-142-3p/Rac1 aix
Haiyan Xiang, Juesheng Yang, Jin Li, Linhui Yuan, Fei Lu, Chen Liu & Yanhua Tang
Pages: 560-569
Published online: 26 May 2020
AbstractforCitrate pretreatment attenuates hypoxia/reoxygenation-induced cardiomyocyte injury via regulating microRNA-142-3p/Rac1 aix | Full Text | References | PDF (2 MB) | EPUB
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Article
Resveratrol diminishes bisphenol A-induced oxidative stress through TRPM2 channel in the mouse kidney cortical collecting duct cells
Bilal Çiğ & Kenan Yildizhan
Pages: 570-583
Published online: 09 Jun 2020
AbstractforResveratrol diminishes bisphenol A-induced oxidative stress through TRPM2 channel in the mouse kidney cortical collecting duct cells | Full Text | References | PDF (3.3 MB) | EPUB
  • 328 Views
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Article
MTHFD1L as a folate cycle enzyme correlates with prognostic outcome and its knockdown impairs cell invasive behaviors in osteosarcoma via mediating the AKT/mTOR pathway
Lei Wang, Ya Yang, Xiu-Mei Wang, Cheng-Qun Wang, Yuan-Min Zhang & Bing-Liang Li
Pages: 584-590
Published online: 26 May 2020
AbstractforMTHFD1L as a folate cycle enzyme correlates with prognostic outcome and its knockdown impairs cell invasive behaviors in osteosarcoma via mediating the AKT/mTOR pathway | Full Text | References | PDF (1.8 MB) | EPUB
  • 135 Views
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Article
Tanshinone IIA inhibits osteosarcoma growth through modulation of AMPK-Nrf2 signaling pathway
Zengjun Xie, Binbin He, Ziyun Jiang & Liang Zhao
Pages: 591-598
Published online: 04 Jun 2020
AbstractforTanshinone IIA inhibits osteosarcoma growth through modulation of AMPK-Nrf2 signaling pathway | Full Text | References | PDF (1.5 MB) | EPUB
  • 96 Views
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Article
Oxidative stress-induced cardiomyocyte apoptosis is associated with dysregulated Akt/p53 signaling pathway
Nan Zheng, Han Li, Xi Wang, Zaixian Zhao & Dongkai Shan
Pages: 599-604
Published online: 27 May 2020
AbstractforOxidative stress-induced cardiomyocyte apoptosis is associated with dysregulated Akt/p53 signaling pathway | Full Text | References | PDF (1.1 MB) | EPUB
  • 124 Views
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Article
Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2
Santosh K. Maurya, Akhilesh Kumar Maurya, Nidhi Mishra & Hifzur R. Siddique
Pages: 605-612
Published online: 01 Jun 2020
AbstractforVirtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2 | Full Text | References | PDF (1.8 MB) | EPUB
  • 3321 Views
  • 34 CrossRef citations
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Article
Upregulation of miR-92a contributes to blocking goblet cell metaplasia by targeting MUC5AC in asthma
Jihuan Dai, Bo Ma, Xiaolin Wen, Zhouxin Yang & Yingxing Yue
Pages: 613-619
Published online: 22 Jun 2020
AbstractforUpregulation of miR-92a contributes to blocking goblet cell metaplasia by targeting MUC5AC in asthma | Full Text | References | PDF (1.4 MB) | EPUB
  • 147 Views
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Article
Clostridium botulinum neurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells
Orhan Akpınar, Ahmet Özşimşek, Mustafa Güzel & Mustafa Nazıroğlu
Pages: 620-632
Published online: 09 Jul 2020
AbstractforClostridium botulinum neurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells | Full Text | References | PDF (3.4 MB) | EPUB
  • 472 Views
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