Xenobiotica, Volume 35, Issue 1 (2005)

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Xenobiotica, Volume 35, Issue 1 (2005)

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Research Article

Article
Comparison of clearance predictions using primary cultures and suspensions of human hepatocytes
N Blanchard, E Alexandre, C. Abadie, T Lavé, B Heyd, G Mantion, D. Jaeck, L Richert & P Coassolo
Pages: 1-15
Published online: 22 Sep 2008
AbstractforComparison of clearance predictions using primary cultures and suspensions of human hepatocytes | References | PDF (138.5 KB)
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Article
Metabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases
A. K. Fröhlich, U. Girreser & B Clement
Pages: 17-25
Published online: 22 Sep 2008
AbstractforMetabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases | References | PDF (101.7 KB)
  • 124 Views
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Article
Stereoselective inhibition of cytochrome P450 forms by lansoprazole and omeprazole in vitro
K. H. Liu, M. J. Kim, J. H. Shon, Y. S. Moon, S. Y. Seol, W Kang, I. J. Cha & J. G. Shin
Pages: 27-38
Published online: 22 Sep 2008
AbstractforStereoselective inhibition of cytochrome P450 forms by lansoprazole and omeprazole in vitro | References | PDF (122.5 KB)
  • 170 Views
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Article
Cytochrome P450-dependent metabolism of gefitinib
D. Mckillop, A. D. McCormick, A. Millar, G. S. Miles, P. J. Phillips & M Hutchison
Pages: 39-50
Published online: 22 Sep 2008
AbstractforCytochrome P450-dependent metabolism of gefitinib | References | PDF (132.4 KB)
  • 468 Views
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Article
AhR and PPARa: antagonistic effects on CYP2B and CYP3A, and additive inhibitory effects on CYP2C11
Z. Shaban, M Soliman, S El-Shazly, K. El-Bohi, A. Abdelazeez, K. Kehelo, H.-S. Kim, K. Muzandu, M Ishizuka, A. Kazusaka & S Fujita
Pages: 51-68
Published online: 22 Sep 2008
AbstractforAhR and PPARa: antagonistic effects on CYP2B and CYP3A, and additive inhibitory effects on CYP2C11 | References | PDF (169.5 KB)
  • 137 Views
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Article
Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers
S Yamaori, H Yamazaki, S Iwano, K. Kiyotani, K. Matsumura, T Saito, A. Parkinson, K. Nakagawa & T Kamataki
Pages: 69-83
Published online: 22 Sep 2008
AbstractforEthnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers | References | PDF (157.3 KB)
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Article
Species differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs
K. Haraguchi, Y Kato, N Koga & M Degawa
Pages: 85-96
Published online: 22 Sep 2008
AbstractforSpecies differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs | References | PDF (178.4 KB)
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Article
Identification of glutathione conjugates and mercapturic acids of 1,2-dibromopropane in female BALB/c mice by liquid chromatography-electrospray ionization tandem mass spectrometry
S. K. Lee, C. H. Jin, S. H. Hyun, D. W. Lee, G. H. Kim, T. W. Jeon, J Lee, D. H. Kim, H. G. Jeong, E. S. Lee & T. C. Jeong
Pages: 97-105
Published online: 22 Sep 2008
AbstractforIdentification of glutathione conjugates and mercapturic acids of 1,2-dibromopropane in female BALB/c mice by liquid chromatography-electrospray ionization tandem mass spectrometry | References | PDF (109.8 KB)
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Article
Isolation, identification and excretion profile of the principal urinary metabolite of the recently banned designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP) in rats
H Tsutsumi, M Katagi, A. Miki, N Shima, T Kamata, K. Nakajima, H Inoue, T Kishi & H Tsuchihashi
Pages: 107-116
Published online: 22 Sep 2008
AbstractforIsolation, identification and excretion profile of the principal urinary metabolite of the recently banned designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP) in rats | References | PDF (210.3 KB)
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