Xenobiotica, Volume 40, Issue 8 (2010)

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Xenobiotica, Volume 40, Issue 8 (2010)

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General Xenobiochemistry

Article
Expression and inducibility by phenobarbital of CYP2C33, CYP2C42, CYP2C49, CYP2B22, and CYP3As in porcine liver, kidney, small intestine, and nasal tissues
Emanuela Puccinelli, Pier Giovanni Gervasi, Margherita La Marca, Pascale Beffy & Vincenzo Longo
Pages: 525-535
Published online: 28 May 2010
AbstractforExpression and inducibility by phenobarbital of CYP2C33, CYP2C42, CYP2C49, CYP2B22, and CYP3As in porcine liver, kidney, small intestine, and nasal tissues | Full Text | References | PDF (1 MB)
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Article
The in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19
Yuan Chen, Hua-fen Liu, Liling Liu, Khanh Nguyen, Elliott B. Jones & Adrian J. Fretland
Pages: 536-546
Published online: 09 Jun 2010
AbstractforThe in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19 | Full Text | References | PDF (924 KB)
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Article
Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae
W. Alderton, S. Berghmans, P. Butler, H. Chassaing, A. Fleming, Z. Golder, F. Richards & I. Gardner
Pages: 547-557
Published online: 09 Jun 2010
AbstractforAccumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae | Full Text | References | PDF (830.9 KB)
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Animal Pharmacokinetics and Metabolism

Article
The effect of acute administration of rifampicin and imatinib on the enterohepatic transport of rosuvastatin in vivo
E. Bergman, M. Hedeland, U. Bondesson & H. Lennernäs
Pages: 558-568
Published online: 28 Jun 2010
AbstractforThe effect of acute administration of rifampicin and imatinib on the enterohepatic transport of rosuvastatin in vivo | Full Text | References | PDF (756.3 KB)
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Article
Metabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion
Tetsuya Tajika, Hiroaki Takahashi, Yusuke Sakai, Hiroyuki Fujii, Akiharu Isowaki & Hideyuki Sakaki
Pages: 569-577
Published online: 28 May 2010
AbstractforMetabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion | Full Text | References | PDF (808.1 KB)
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Article
Disposition of bazedoxifene in rats
A. Chandrasekaran, S. Ahmad, L. Shen, W. DeMaio, T. Hultin & J. Scatina
Pages: 578-585
Published online: 07 Jun 2010
AbstractforDisposition of bazedoxifene in rats | Full Text | References | PDF (688.4 KB)
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Article
Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis
Olga Nemirovskiy, Yi J. Zheng, David Tung, Brian Korniski, Steve Settle, Adam Skepner, Matthew Yates, Poonam Aggarwal, Teresa Sunyer & Dean J. Aguiar
Pages: 586-592
Published online: 28 May 2010
AbstractforPharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis | Full Text | References | PDF (805.5 KB)
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