Cancer Biology & Therapy, Volume 7, Issue 2 (2008)

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Cancer Biology & Therapy, Volume 7, Issue 2 (2008)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 04 Feb 2008
AbstractforCover Image | PDF (8 MB)
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Review

Review Article
Cytokine polymorphisms and gastric cancer risk: An evolving view
Barbara G. Schneider, M. Constanza Camargo, Kelli K. Ryckman, Liviu A. Sicinschi, M. Blanca Piazuelo, Jovanny Zabaleta, Pelayo Correa & Scott M. Williams
Pages: 157-162
Published online: 04 Feb 2008
AbstractforCytokine polymorphisms and gastric cancer risk: An evolving view | PDF (155.2 KB)
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Review Article
Modulation of death receptors by cancer therapeutic agents
Heath A. Elrod & Shi-Yong Sun
Pages: 163-173
Published online: 04 Feb 2008
AbstractforModulation of death receptors by cancer therapeutic agents | PDF (317.3 KB)
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Research Paper

Article
Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia
Jiezhong Chen & Nigel A.J. McMillan
Pages: 174-179
Published online: 04 Feb 2008
AbstractforMolecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia | PDF (161.7 KB)
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Article
Mechanisms of Cables 1 gene inactivation in human ovarian cancer development
Hideo Sakamoto, Anne M. Friel, Antony W. Wood, Lankai Guo, Ana Ilic, Michael V. Seiden, Daniel C. Chung, Maureen P. Lynch, Takehiro Serikawa, Elizabeth Munro, Esther Oliva, Sandra Orsulic, Sandra D. Kirley, Rosemary Foster, Lawrence R. Zukerberg & Bo R. Rueda
Pages: 180-188
Published online: 04 Feb 2008
AbstractforMechanisms of Cables 1 gene inactivation in human ovarian cancer development | PDF (575.1 KB)
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Commentary

Learning about ovarian tumorigenesis by watching Cables
Patrice J. Morin
Pages: 189-190
Published online: 04 Feb 2008
AbstractforLearning about ovarian tumorigenesis by watching Cables | PDF (69.9 KB)
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Research Paper

Article
Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response
Zhen Ren, Xun Ye, Chao Fang, Qin Lu, Yi Zhao, Fang Liu, Min Liang, Fang Hu & Hong-Zhuan Chen
Pages: 191-195
Published online: 04 Feb 2008
AbstractforIntratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response | PDF (261.7 KB)
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Commentary

Enhancing antitumor immune response by HSPs
Bingliang Fang & Wei Guo
Pages: 196-197
Published online: 04 Feb 2008
AbstractforEnhancing antitumor immune response by HSPs | PDF (68 KB)
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Research Paper

Article
Mitochondrial DNA somatic mutations are frequent in nasopharyngeal carcinoma
Ling-Juan Pang, Jian-Yong Shao, Xiao-Man Liang, Yun-Fei Xia & Yi-Xin Zeng
Pages: 198-207
Published online: 04 Feb 2008
AbstractforMitochondrial DNA somatic mutations are frequent in nasopharyngeal carcinoma | PDF (560.3 KB)
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Article
Upregulation of stress-response genes with cell cycle arrest induced by carbon ion irradiation in multiple murine tumors models
Kaori Imadome, Mayumi Iwakawa, Kazunori Nojiri, Tomoaki Tamaki, Minako Sakai, Miyako Nakawatari, Takashi Moritake, Mitsuru Yanagisawa, Etsuko Nakamura, Hirohiko Tsujii & Takashi Imai
Pages: 208-217
Published online: 04 Feb 2008
AbstractforUpregulation of stress-response genes with cell cycle arrest induced by carbon ion irradiation in multiple murine tumors models | PDF (1.4 MB)
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Article
Enhancement of p53 gene transfer efficiency in hepatic tumor mediated by transferrin receptor through trans-arterial delivery
Qin Lu, Gao-Jun Teng, Yue Zhang, Huan-Zhang Niu, Guang-Yu Zhu, Yan-Li An, Hui Yu, Guo-Zhao Li, Ding-Hong Qiu & Chuan-Ging Wu
Pages: 218-224
Published online: 04 Feb 2008
AbstractforEnhancement of p53 gene transfer efficiency in hepatic tumor mediated by transferrin receptor through trans-arterial delivery | PDF (391.5 KB)
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Commentary

Safe and efficient gene therapy-delivery makes all the difference
Ramaswamy Suvasini & Kumaravel Somasundaram
Pages: 225-227
Published online: 04 Feb 2008
AbstractforSafe and efficient gene therapy-delivery makes all the difference | PDF (358.2 KB)
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Research Paper

Article
hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells
Ying Shen, Yong-Wei Zhang, Zhi-Xiang Zhang, Ze-Hong Miao & Jian Ding
Pages: 228-236
Published online: 04 Feb 2008
AbstractforhTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells | PDF (756.3 KB)
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Article
Chimeric toxins inhibit growth of primary oral squamous cell carcinoma cells
Christopher Bachran, Iring Heisler, Diana Bachran, Katrin Dassler, Matthias F. Melzig, Jürgen Ervens & Hendrik Fuchs
Pages: 237-242
Published online: 04 Feb 2008
AbstractforChimeric toxins inhibit growth of primary oral squamous cell carcinoma cells | PDF (179.6 KB)
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Commentary

Killing cancer cells by targeting the EGF receptor
Tomas Girbés, Lucia Citores, Jose Ferreras & Rosario Iglesias
Pages: 243-244
Published online: 04 Feb 2008
AbstractforKilling cancer cells by targeting the EGF receptor | PDF (153.2 KB)
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Research Paper

Article
The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo
Yan-rong Lu, Yu Yuan, Xiu-jie Wang, Ling-ling Wei, You-nan Chen, Cong Cong, Sheng-fu Li, Dan Long, Wei-dong Tan, Ying-qiu Mao, Jie Zhang, You-ping Li & Jing-qiu Cheng
Pages: 245-251
Published online: 04 Feb 2008
AbstractforThe growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo | PDF (456.7 KB)
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Commentary

Mesenchymal stem cells in cancer: Friends or foes?
Wengeng Zhang
Pages: 252-254
Published online: 04 Feb 2008
AbstractforMesenchymal stem cells in cancer: Friends or foes? | PDF (272.6 KB)
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Research Paper

Article
miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer
Antonis Giannakakis, Raphael Sandaltzopoulos, Joel Greshock, Shun Liang, Jia Huang, Kosei Hasegawa, Chunsheng Li, Ann O'Brien-Jenkins, Dionyssios Katsaros, Barbara L. Weber, Celeste Simon, George Coukos & Lin Zhang
Pages: 255-264
Published online: 04 Feb 2008
AbstractformiR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer | PDF (411 KB)
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Commentary

Hypoxic regulation of miR-210: Shrinking targets expand HIF-1’s Influence
Paul G. Corn
Pages: 265-267
Published online: 04 Feb 2008
AbstractforHypoxic regulation of miR-210: Shrinking targets expand HIF-1’s Influence | PDF (80.6 KB)
  • 344 Views
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Research Paper

Article
Silencing of Wnt-1 by siRNA induces apoptosis of MCF-7 human breast cancer cells
Maciej Wieczorek, Aleksandra Paczkowska, Piotr Guzenda, Maria Majorek, Andrzej K. Bednarek & Monika Lamparska-Przybysz
Pages: 268-274
Published online: 04 Feb 2008
AbstractforSilencing of Wnt-1 by siRNA induces apoptosis of MCF-7 human breast cancer cells | PDF (473.8 KB)
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Commentary

Article Commentary
RNA technology targeted to the WNT signaling pathway
Masaru Katoh
Pages: 275-277
Published online: 04 Feb 2008
AbstractforRNA technology targeted to the WNT signaling pathway | PDF (90.1 KB)
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Research Paper

Article
Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation
Silvana Morello, Antonello Petrella, Michela Festa, Ada Popolo, Mario Monaco, Emilia Vuttariello, Gennaro Chiappetta, Luca Parente & Aldo Pinto
Pages: 278-284
Published online: 04 Feb 2008
AbstractforCl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation | PDF (743.5 KB)
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Article
Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L
Takeyuki Sugiura, Yoshie Noguchi, Kayo Sakurai & Chiharu Hattori
Pages: 285-292
Published online: 04 Feb 2008
AbstractforProtein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L | PDF (544.4 KB)
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Commentary

PPM1H: New kid on the block
Sathyavageeswaran Shreeram & Dmitry V. Bulavin
Pages: 293-294
Published online: 04 Feb 2008
AbstractforPPM1H: New kid on the block | PDF (75.4 KB)
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Research Paper

Article
Lyprinol™ only partially improves indicators of small intestinal integrity in a rat model of 5-fluorouracil-induced mucositis
Diana M. Torres, Katie L. Tooley, Ross N. Butler, Cassie L. Smith, Mark S. Geier & Gordon S. Howarth
Pages: 295-302
Published online: 04 Feb 2008
AbstractforLyprinol™ only partially improves indicators of small intestinal integrity in a rat model of 5-fluorouracil-induced mucositis | PDF (287.7 KB)
  • 569 Views
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Article
Application of Doxorubicin-induced rAAV2-p53 gene delivery in combined chemotherapy and gene therapy for hepatocellular carcinoma
Chun-Ann Chen, Cheng-Kai Lo, Bai-Ling Lin, Eric Sibley & Shiue-Cheng Tang
Pages: 303-309
Published online: 04 Feb 2008
AbstractforApplication of Doxorubicin-induced rAAV2-p53 gene delivery in combined chemotherapy and gene therapy for hepatocellular carcinoma | PDF (901.8 KB)
  • 275 Views
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Article
Response and determinants of cancer cell susceptibility to PI3K inhibitors: Combined targeting of PI3K and Mek1 as an effective anticancer strategy
Ker Yu, Lourdes Toral-Barza, Celine Shi, Wei-Guo Zhang & Arie Zask
Pages: 310-318
Published online: 04 Feb 2008
AbstractforResponse and determinants of cancer cell susceptibility to PI3K inhibitors: Combined targeting of PI3K and Mek1 as an effective anticancer strategy | PDF (814.1 KB)
  • 548 Views
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Commentary

Tumor growth signaling inhibition: Targeting multiple pathways
Oliver Sampson & Eric Bernhard
Pages: 319-321
Published online: 04 Feb 2008
AbstractforTumor growth signaling inhibition: Targeting multiple pathways | PDF (120.1 KB)
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