Molecular and Cellular Biology, Volume 22, Issue 1 (2002)

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Molecular and Cellular Biology, Volume 22, Issue 1 (2002)

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Transcriptional Regulation

Article
Protein Kinase A Regulates Sexual Development and Gluconeogenesis through Phosphorylation of the Zn Finger Transcriptional Activator Rst2p in Fission Yeast
Toru Higuchi, Yoshinori Watanabe & Masayuki Yamamoto
Pages: 1-11
Published online: 27 Mar 2023
AbstractforProtein Kinase A Regulates Sexual Development and Gluconeogenesis through Phosphorylation of the Zn Finger Transcriptional Activator Rst2p in Fission Yeast | Full Text | References | PDF (412.5 KB)
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Article
c-Jun and Hypoxia-Inducible Factor 1 Functionally Cooperate in Hypoxia-Induced Gene Transcription
Arántzazu Alfranca, M. Dolores Gutiérrez, Alicia Vara, Julián Aragonés, Felipe Vidal & Manuel O. Landázuri
Pages: 12-22
Published online: 27 Mar 2023
Abstractforc-Jun and Hypoxia-Inducible Factor 1 Functionally Cooperate in Hypoxia-Induced Gene Transcription | Full Text | References | PDF (384.5 KB)
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Article
Strong Natural Pausing by RNA Polymerase II within 10 Bases of Transcription Start May Result in Repeated Slippage and Reextension of the Nascent RNA
Mahadeb Pal & Donal S. Luse
Pages: 30-40
Published online: 27 Mar 2023
AbstractforStrong Natural Pausing by RNA Polymerase II within 10 Bases of Transcription Start May Result in Repeated Slippage and Reextension of the Nascent RNA | Full Text | References | PDF (353.6 KB)
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Article
p300-Mediated Tax Transactivation from Recombinant Chromatin: Histone Tail Deletion Mimics Coactivator Function
Sara A. Georges, W. Lee Kraus, Karolin Luger, Jennifer K. Nyborg & Paul J. Laybourn
Pages: 127-137
Published online: 27 Mar 2023
Abstractforp300-Mediated Tax Transactivation from Recombinant Chromatin: Histone Tail Deletion Mimics Coactivator Function | Full Text | References | PDF (408.6 KB)
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Article
Distinct Domains of Erythroid Kruüppel-Like Factor Modulate Chromatin Remodeling and Transactivation at the Endogenous β-Globin Gene Promoter
R. Clark Brown, Scott Pattison, Janine van Ree, Elise Coghill, Andrew Perkins, Stephen M. Jane & John M. Cunningham
Pages: 161-170
Published online: 27 Mar 2023
AbstractforDistinct Domains of Erythroid Kruüppel-Like Factor Modulate Chromatin Remodeling and Transactivation at the Endogenous β-Globin Gene Promoter | Full Text | References | PDF (301.7 KB)
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Article
Interaction between P-TEFb and the C-Terminal Domain of RNA Polymerase II Activates Transcriptional Elongation from Sites Upstream or Downstream of Target Genes
Ran Taube, Xin Lin, Dan Irwin, Koh Fujinaga & B. Matija Peterlin
Pages: 321-331
Published online: 27 Mar 2023
AbstractforInteraction between P-TEFb and the C-Terminal Domain of RNA Polymerase II Activates Transcriptional Elongation from Sites Upstream or Downstream of Target Genes | Full Text | References | PDF (588.1 KB)
  • 39 Views
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Article
Identification and Characterization of a Tissue-Specific Coactivator, GT198, That Interacts with the DNA-Binding Domains of Nuclear Receptors
Lan Ko, Guemalli R. Cardona, Alexandra Henrion-Caude & William W. Chin
Pages: 357-369
Published online: 27 Mar 2023
AbstractforIdentification and Characterization of a Tissue-Specific Coactivator, GT198, That Interacts with the DNA-Binding Domains of Nuclear Receptors | Full Text | References | PDF (755.3 KB)
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Cell Growth and Development

Article
Defective Signaling in a Subpopulation of CD4+ T Cells in the Absence of Ca2+/Calmodulin-Dependent Protein Kinase IV
Kristin A. Anderson & Anthony R. Means
Pages: 23-29
Published online: 27 Mar 2023
AbstractforDefective Signaling in a Subpopulation of CD4+ T Cells in the Absence of Ca2+/Calmodulin-Dependent Protein Kinase IV | Full Text | References | PDF (246.7 KB)
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Article
Cytoplasmic Death Signal Triggered by Src-Mediated Phosphorylation of the Adenovirus E4orf4 Protein
Marie-Claude Gingras, Claudia Champagne, Mélanie Roy & Josée N. Lavoie
Pages: 41-56
Published online: 27 Mar 2023
AbstractforCytoplasmic Death Signal Triggered by Src-Mediated Phosphorylation of the Adenovirus E4orf4 Protein | Full Text | References | PDF (781.2 KB)
  • 15 Views
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Article
CAK1 Promotes Meiosis and Spore Formation in Saccharomyces cerevisiae in a CDC28-Independent Fashion
Michael Schaber, Anne Lindgren, Karen Schindler, David Bungard, Philipp Kaldis & Edward Winter
Pages: 57-68
Published online: 27 Mar 2023
AbstractforCAK1 Promotes Meiosis and Spore Formation in Saccharomyces cerevisiae in a CDC28-Independent Fashion | Full Text | References | PDF (325 KB)
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Article
Novel Function of the Cyclin A Binding Site of E2F in Regulating p53-Induced Apoptosis in Response to DNA Damage
Jung-Kuang Hsieh, Damian Yap, Daniel J. O’Connor, Valentina Fogal, Lynn Fallis, Florence Chan, Shan Zhong & Xin Lu
Pages: 78-93
Published online: 27 Mar 2023
AbstractforNovel Function of the Cyclin A Binding Site of E2F in Regulating p53-Induced Apoptosis in Response to DNA Damage | Full Text | References | PDF (880.6 KB)
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Article
Bcl-2 Family Members and Functional Electron Transport Chain Regulate Oxygen Deprivation-Induced Cell Death
David S. McClintock, Matthew T. Santore, Vivian Y. Lee, Joslyn Brunelle, G. R. Scott Budinger, Wei-Xing Zong, Craig B. Thompson, Nissim Hay & Navdeep S. Chandel
Pages: 94-104
Published online: 27 Mar 2023
AbstractforBcl-2 Family Members and Functional Electron Transport Chain Regulate Oxygen Deprivation-Induced Cell Death | Full Text | References | PDF (462.1 KB)
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Article
Mammalian Orc1 Protein Is Selectively Released from Chromatin and Ubiquitinated during the S-to-M Transition in the Cell Division Cycle
Cong-Jun Li & Melvin L. DePamphilis
Pages: 105-116
Published online: 27 Mar 2023
AbstractforMammalian Orc1 Protein Is Selectively Released from Chromatin and Ubiquitinated during the S-to-M Transition in the Cell Division Cycle | Full Text | References | PDF (619.4 KB)
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Article
Stat6 and IRS-2 Cooperate in Interleukin 4 (IL-4)-Induced Proliferation and Differentiation but Are Dispensable for IL-4-Dependent Rescue from Apoptosis
Andrea L. Wurster, Dominic J. Withers, Tohru Uchida, Morris F. White & Michael J. Grusby
Pages: 117-126
Published online: 27 Mar 2023
AbstractforStat6 and IRS-2 Cooperate in Interleukin 4 (IL-4)-Induced Proliferation and Differentiation but Are Dispensable for IL-4-Dependent Rescue from Apoptosis | Full Text | References | PDF (438.9 KB)
  • 63 Views
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Article
Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation
Martin O. Bergo, Patricia Ambroziak, Cria Gregory, Amanda George, James C. Otto, Edward Kim, Hiroki Nagase, Patrick J. Casey, Allan Balmain & Stephen G. Young
Pages: 171-181
Published online: 27 Mar 2023
AbstractforAbsence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation | Full Text | References | PDF (500.2 KB)
  • 41 Views
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Article
Tyrosine Phosphorylation of Protein Kinase Cδ Is Essential for Its Apoptotic Effect in Response to Etoposide
Michal Blass, Ilana Kronfeld, Gila Kazimirsky, Peter M. Blumberg & Chaya Brodie
Pages: 182-195
Published online: 27 Mar 2023
AbstractforTyrosine Phosphorylation of Protein Kinase Cδ Is Essential for Its Apoptotic Effect in Response to Etoposide | Full Text | References | PDF (871.1 KB)
  • 17 Views
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Article
ARF Function Does Not Require p53 Stabilization or Mdm2 Relocalization
Chandrashekhar Korgaonkar, Lili Zhao, Modestos Modestou & Dawn E. Quelle
Pages: 196-206
Published online: 27 Mar 2023
AbstractforARF Function Does Not Require p53 Stabilization or Mdm2 Relocalization | Full Text | References | PDF (611.5 KB)
  • 26 Views
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Article
Molecular Ordering of the Initial Signaling Events of CD95
Alicia Algeciras-Schimnich, Le Shen, Bryan C. Barnhart, Andrea E. Murmann, Janis K. Burkhardt & Marcus E. Peter
Pages: 207-220
Published online: 27 Mar 2023
AbstractforMolecular Ordering of the Initial Signaling Events of CD95 | Full Text | References | PDF (941.4 KB)
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Article
Gab3, a New DOS/Gab Family Member, Facilitates Macrophage Differentiation
Ingrid Wolf, Brendan J. Jenkins, Yan Liu, Martina Seiffert, Joseph M. Custodio, Paul Young & Larry R. Rohrschneider
Pages: 231-244
Published online: 27 Mar 2023
AbstractforGab3, a New DOS/Gab Family Member, Facilitates Macrophage Differentiation | Full Text | References | PDF (1,019.3 KB)
  • 38 Views
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Article
v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation
N. O. Carragher, M. A. Westhoff, D. Riley, D. A. Potter, P. Dutt, J. S. Elce, P. A. Greer & M. C. Frame
Pages: 257-269
Published online: 27 Mar 2023
Abstractforv-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation | Full Text | References | PDF (698.7 KB)
  • 35 Views
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Article
Erk5 Participates in Neuregulin Signal Transduction and Is Constitutively Active in Breast Cancer Cells Overexpressing ErbB2
Azucena Esparís-Ogando, Elena Díaz-Rodríguez, Juan Carlos Montero, Laura Yuste, Piero Crespo & Atanasio Pandiella
Pages: 270-285
Published online: 27 Mar 2023
AbstractforErk5 Participates in Neuregulin Signal Transduction and Is Constitutively Active in Breast Cancer Cells Overexpressing ErbB2 | Full Text | References | PDF (738.8 KB)
  • 37 Views
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Article
p19ARF Is Dispensable for Oncogenic Stress-Induced p53-Mediated Apoptosis and Tumor Suppression In Vivo
Dawn Tolbert, Xiangdong Lu, Chaoying Yin, Mathew Tantama & Terry Van Dyke
Pages: 370-377
Published online: 27 Mar 2023
Abstractforp19ARF Is Dispensable for Oncogenic Stress-Induced p53-Mediated Apoptosis and Tumor Suppression In Vivo | Full Text | References | PDF (1.3 MB)
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Dna Dynamics and Chromosome Structure

Article
Assembly of the RAG1/RAG2 Synaptic Complex
Cynthia L. Mundy, Nadja Patenge, Adam G. W. Matthews & Marjorie A. Oettinger
Pages: 69-77
Published online: 27 Mar 2023
AbstractforAssembly of the RAG1/RAG2 Synaptic Complex | Full Text | References | PDF (289 KB)
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Article
Yeast hnRNP K-Like Genes Are Involved in Regulation of the Telomeric Position Effect and Telomere Length
Oleg Denisenko & Karol Bomsztyk
Pages: 286-297
Published online: 27 Mar 2023
AbstractforYeast hnRNP K-Like Genes Are Involved in Regulation of the Telomeric Position Effect and Telomere Length | Full Text | References | PDF (543.2 KB)
  • 16 Views
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Article
Novel Fission Yeast Cdc7-Dbf4-Like Kinase Complex Required for the Initiation and Progression of Meiotic Second Division
Taro Nakamura, Michiko Nakamura-Kubo, Tomohiro Nakamura & Chikashi Shimoda
Pages: 309-320
Published online: 27 Mar 2023
AbstractforNovel Fission Yeast Cdc7-Dbf4-Like Kinase Complex Required for the Initiation and Progression of Meiotic Second Division | Full Text | References | PDF (1 MB)
  • 21 Views
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Article
Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres
Brandoch D. Cook, Jasmin N. Dynek, William Chang, Grigoriy Shostak & Susan Smith
Pages: 332-342
Published online: 27 Mar 2023
AbstractforRole for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres | Full Text | References | PDF (583.9 KB)
  • 63 Views
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Cell and Organelle Structure and Assembly

Article
Protection from Free β-Tubulin by the β-Tubulin Binding Protein Rbl2p
Katharine C. Abruzzi, Adelle Smith, William Chen & Frank Solomon
Pages: 138-147
Published online: 27 Mar 2023
AbstractforProtection from Free β-Tubulin by the β-Tubulin Binding Protein Rbl2p | Full Text | References | PDF (256.4 KB)
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Gene Expression

Article
SRm160 Splicing Coactivator Promotes Transcript 3′-End Cleavage
Susan McCracken, Mark Lambermon & Benjamin J. Blencowe
Pages: 148-160
Published online: 27 Mar 2023
AbstractforSRm160 Splicing Coactivator Promotes Transcript 3′-End Cleavage | Full Text | References | PDF (521.7 KB)
  • 30 Views
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Article
Characterization of U2AF26, a Splicing Factor Related to U2AF35
Jeremiah Shepard, Martin Reick, Sara Olson & Brenton R. Graveley
Pages: 221-230
Published online: 27 Mar 2023
AbstractforCharacterization of U2AF26, a Splicing Factor Related to U2AF35 | Full Text | References | PDF (572.7 KB)
  • 42 Views
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Article
Multiple Roles of the τ131 Subunit of Yeast Transcription Factor IIIC (TFIIIC) in TFIIIB Assembly
Hélène Dumay-Odelot, Joël Acker, Rosalia Arrebola, André Sentenac & Christian Marck
Pages: 298-308
Published online: 27 Mar 2023
AbstractforMultiple Roles of the τ131 Subunit of Yeast Transcription Factor IIIC (TFIIIC) in TFIIIB Assembly | Full Text | References | PDF (766.7 KB)
  • 26 Views
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Article
The RNA Binding Protein Nuclear Factor 90 Functions as Both a Positive and Negative Regulator of Gene Expression in Mammalian Cells
Trevor W. Reichman, Luis C. Muñiz & Michael B. Mathews
Pages: 343-356
Published online: 27 Mar 2023
AbstractforThe RNA Binding Protein Nuclear Factor 90 Functions as Both a Positive and Negative Regulator of Gene Expression in Mammalian Cells | Full Text | References | PDF (510.6 KB)
  • 27 Views
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Nucleocytoplasmic Communication

Article
Formation of Tap/NXT1 Heterodimers Activates Tap-Dependent Nuclear mRNA Export by Enhancing Recruitment to Nuclear Pore Complexes
Heather L. Wiegand, Glen A. Coburn, Yan Zeng, Yibin Kang, Hal P. Bogerd & Bryan R. Cullen
Pages: 245-256
Published online: 27 Mar 2023
AbstractforFormation of Tap/NXT1 Heterodimers Activates Tap-Dependent Nuclear mRNA Export by Enhancing Recruitment to Nuclear Pore Complexes | Full Text | References | PDF (447.5 KB)
  • 32 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
The Septin CDCrel-1 Is Dispensable for Normal Development and Neurotransmitter Release
Xiao-Rong Peng, Zhengping Jia, Yu Zhang, Jerry Ware & William S. Trimble
Pages: 378-387
Published online: 27 Mar 2023
AbstractforThe Septin CDCrel-1 Is Dispensable for Normal Development and Neurotransmitter Release | Full Text | References | PDF (653 KB)
  • 23 Views
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