Molecular and Cellular Biology, Volume 22, Issue 14 (2002)

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Molecular and Cellular Biology, Volume 22, Issue 14 (2002)

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Cell Growth and Development

Article
The SIN3/RPD3 Deacetylase Complex Is Essential for G2 Phase Cell Cycle Progression and Regulation of SMRTER Corepressor Levels
Lori A. Pile, Erin M. Schlag & David A. Wassarman
Pages: 4965-4976
Published online: 27 Mar 2023
AbstractforThe SIN3/RPD3 Deacetylase Complex Is Essential for G2 Phase Cell Cycle Progression and Regulation of SMRTER Corepressor Levels | Full Text | References | PDF (455 KB)
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Article
Predisposition to Arrhythmia and Autonomic Dysfunction in Nhlh1-Deficient Mice
Tiziana Cogliati, Deborah J. Good, Mark Haigney, Petra Delgado-Romero, Michael A. Eckhaus, Walter J. Koch & Ilan R. Kirsch
Pages: 4977-4983
Published online: 27 Mar 2023
AbstractforPredisposition to Arrhythmia and Autonomic Dysfunction in Nhlh1-Deficient Mice | Full Text | References | PDF (157.7 KB)
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Article
14-3-3 Antagonizes Ras-Mediated Raf-1 Recruitment to the Plasma Membrane To Maintain Signaling Fidelity
Yvonne Light, Hugh Paterson & Richard Marais
Pages: 4984-4996
Published online: 27 Mar 2023
Abstractfor14-3-3 Antagonizes Ras-Mediated Raf-1 Recruitment to the Plasma Membrane To Maintain Signaling Fidelity | Full Text | References | PDF (491.5 KB)
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Article
Nir2, a Human Homolog of Drosophila melanogaster Retinal Degeneration B Protein, Is Essential for Cytokinesis
Vladimir Litvak, Donguha Tian, Shari Carmon & Sima Lev
Pages: 5064-5075
Published online: 27 Mar 2023
AbstractforNir2, a Human Homolog of Drosophila melanogaster Retinal Degeneration B Protein, Is Essential for Cytokinesis | Full Text | References | PDF (1.1 MB)
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Article
Dissection of a Complex Phenotype by Functional Genomics Reveals Roles for the Yeast Cyclin-Dependent Protein Kinase Pho85 in Stress Adaptation and Cell Integrity
Dongqing Huang, Jason Moffat & Brenda Andrews
Pages: 5076-5088
Published online: 27 Mar 2023
AbstractforDissection of a Complex Phenotype by Functional Genomics Reveals Roles for the Yeast Cyclin-Dependent Protein Kinase Pho85 in Stress Adaptation and Cell Integrity | Full Text | References | PDF (1,013.9 KB)
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Article
H-Ras Signaling and K-Ras Signaling Are Differentially Dependent on Endocytosis
Sandrine Roy, Bruce Wyse & John F. Hancock
Pages: 5128-5140
Published online: 27 Mar 2023
AbstractforH-Ras Signaling and K-Ras Signaling Are Differentially Dependent on Endocytosis | Full Text | References | PDF (1 MB)
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Article
A Two-Stage, p16INK4A- and p53-Dependent Keratinocyte Senescence Mechanism That Limits Replicative Potential Independent of Telomere Status
James G. Rheinwald, William C. Hahn, Matthew R. Ramsey, Jenny Y. Wu, Zongyou Guo, Hensin Tsao, Michele De Luca, Caterina Catricalà & Kathleen M. O'Toole
Pages: 5157-5172
Published online: 27 Mar 2023
AbstractforA Two-Stage, p16INK4A- and p53-Dependent Keratinocyte Senescence Mechanism That Limits Replicative Potential Independent of Telomere Status | Full Text | References | PDF (1.4 MB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
CUL-4A Is Critical for Early Embryonic Development
Binghui Li, Joseph C. Ruiz & Kristin T. Chun
Pages: 4997-5005
Published online: 27 Mar 2023
AbstractforCUL-4A Is Critical for Early Embryonic Development | Full Text | References | PDF (301.9 KB)
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Article
The Absence of Tssc6, a Member of the Tetraspanin Superfamily, Does Not Affect Lymphoid Development but Enhances In Vitro T-Cell Proliferative Responses
Jacqueline M. Tarrant, Joanna Groom, Donald Metcalf, Ruili Li, Bette Borobokas, Mark D. Wright, David Tarlinton & Lorraine Robb
Pages: 5006-5018
Published online: 27 Mar 2023
AbstractforThe Absence of Tssc6, a Member of the Tetraspanin Superfamily, Does Not Affect Lymphoid Development but Enhances In Vitro T-Cell Proliferative Responses | Full Text | References | PDF (315.4 KB)
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Article
Neither Agouti-Related Protein nor Neuropeptide Y Is Critically Required for the Regulation of Energy Homeostasis in Mice
Su Qian, Howard Chen, Drew Weingarth, Myrna E. Trumbauer, Dawn E. Novi, Xiaoming Guan, Hong Yu, Zhu Shen, Yue Feng, Easter Frazier, Airu Chen, Ramon E. Camacho, Lauren P. Shearman, Shobhna Gopal-Truter, Douglas J. MacNeil, Lex H. T. Van der Ploeg & Donald J. Marsh
Pages: 5027-5035
Published online: 27 Mar 2023
AbstractforNeither Agouti-Related Protein nor Neuropeptide Y Is Critically Required for the Regulation of Energy Homeostasis in Mice | Full Text | References | PDF (204 KB)
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Article
Astrocyte-Specific Inactivation of the Neurofibromatosis 1 Gene (NF1) Is Insufficient for Astrocytoma Formation
Michaela Livia Bajenaru, Yuan Zhu, Nicolé M. Hedrick, Jessica Donahoe, Luis F. Parada & David H. Gutmann
Pages: 5100-5113
Published online: 27 Mar 2023
AbstractforAstrocyte-Specific Inactivation of the Neurofibromatosis 1 Gene (NF1) Is Insufficient for Astrocytoma Formation | Full Text | References | PDF (1.2 MB)
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Article
Generation of Mice Deficient for Macrophage Galactose- and N-Acetylgalactosamine-Specific Lectin: Limited Role in Lymphoid and Erythroid Homeostasis and Evidence for Multiple Lectins
Thandi M. Onami, Meei-Yun Lin, Dawne M. Page, Shirley A. Reynolds, Carol D. Katayama, Jamey D. Marth, Tatsuro Irimura, Ajit Varki, Nissi Varki & Stephen M. Hedrick
Pages: 5173-5181
Published online: 27 Mar 2023
AbstractforGeneration of Mice Deficient for Macrophage Galactose- and N-Acetylgalactosamine-Specific Lectin: Limited Role in Lymphoid and Erythroid Homeostasis and Evidence for Multiple Lectins | Full Text | References | PDF (694.7 KB)
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Article
Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice
Misako Haraguchi, Hiroaki Tsujimoto, Masakazu Fukushima, Itsuro Higuchi, Hideto Kuribayashi, Hideo Utsumi, Atsuo Nakayama, Yoshio Hashizume, Junko Hirato, Hiroki Yoshida, Hiromitsu Hara, Shinjiro Hamano, Hiroaki Kawaguchi, Tatsuhiko Furukawa, Kohei Miyazono, Fuyuki Ishikawa, Hideo Toyoshima, Tadashi Kaname, Masaharu Komatsu, Zhe-Sheng Chen, Takenari Gotanda, Tokushi Tachiwada, Tomoyuki Sumizawa, Kazutaka Miyadera, Mitsuhiro Osame, Hiroki Yoshida, Tetsuo Noda, Yuji Yamada & Shin-ichi Akiyama
Pages: 5212-5221
Published online: 27 Mar 2023
AbstractforTargeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice | Full Text | References | PDF (603 KB)
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Article
Characterization of Mice Deficient in the Src Family Nonreceptor Tyrosine Kinase Frk/rak
Subhashini Chandrasekharan, Ting Hu Qiu, Nawal Alkharouf, Kelly Brantley, James B. Mitchell & Edison T. Liu
Pages: 5235-5247
Published online: 27 Mar 2023
AbstractforCharacterization of Mice Deficient in the Src Family Nonreceptor Tyrosine Kinase Frk/rak | Full Text | References | PDF (510.9 KB)
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Transcriptional Regulation

Article
The Class II Transactivator Requires brahma-Related Gene 1 To Activate Transcription of Major Histocompatibility Complex Class II Genes
Rajini Mudhasani & Joseph D. Fontes
Pages: 5019-5026
Published online: 27 Mar 2023
AbstractforThe Class II Transactivator Requires brahma-Related Gene 1 To Activate Transcription of Major Histocompatibility Complex Class II Genes | Full Text | References | PDF (226.5 KB)
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Article
The ETS Domain Transcription Factor Elk-1 Contains a Novel Class of Repression Domain
Shen-Hsi Yang, Donna C. Bumpass, Neil D. Perkins & Andrew D. Sharrocks
Pages: 5036-5046
Published online: 27 Mar 2023
AbstractforThe ETS Domain Transcription Factor Elk-1 Contains a Novel Class of Repression Domain | Full Text | References | PDF (810.6 KB)
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Article
Yng1p Modulates the Activity of Sas3p as a Component of the Yeast NuA3 Histone Acetyltransferase Complex
LeAnn Howe, Thomas Kusch, Nemone Muster, Ranjana Chaterji, John R. Yates III & Jerry L. Workman
Pages: 5047-5053
Published online: 27 Mar 2023
AbstractforYng1p Modulates the Activity of Sas3p as a Component of the Yeast NuA3 Histone Acetyltransferase Complex | Full Text | References | PDF (288.5 KB)
  • 24 Views
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Article
TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins
Mikhail A. Nikiforov, Sanjay Chandriani, Jeonghyeon Park, Iulia Kotenko, Dina Matheos, Anna Johnsson, Steven B. McMahon & Michael D. Cole
Pages: 5054-5063
Published online: 27 Mar 2023
AbstractforTRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins | Full Text | References | PDF (239.2 KB)
  • 69 Views
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Article
The Dorsal Rel Homology Domain Plays an Active Role in Transcriptional Regulation
Songtao Jia, Rubén D. Flores-Saaib & Albert J. Courey
Pages: 5089-5099
Published online: 27 Mar 2023
AbstractforThe Dorsal Rel Homology Domain Plays an Active Role in Transcriptional Regulation | Full Text | References | PDF (718.4 KB)
  • 15 Views
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Article
Selective Cooperation between Fatty Acid Binding Proteins and Peroxisome Proliferator-Activated Receptors in Regulating Transcription
Nguan-Soon Tan, Natacha S. Shaw, Nicolas Vinckenbosch, Peng Liu, Rubina Yasmin, Béatrice Desvergne, Walter Wahli & Noa Noy
Pages: 5114-5127
Published online: 27 Mar 2023
AbstractforSelective Cooperation between Fatty Acid Binding Proteins and Peroxisome Proliferator-Activated Receptors in Regulating Transcription | Full Text | References | PDF (605.6 KB)
  • 143 Views
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Article
Drosophila Mi-2 Negatively Regulates dDREF by Inhibiting Its DNA-Binding Activity
Fumiko Hirose, Nobuko Ohshima, Eun-Jeong Kwon, Hideki Yoshida & Masamitsu Yamaguchi
Pages: 5182-5193
Published online: 27 Mar 2023
AbstractforDrosophila Mi-2 Negatively Regulates dDREF by Inhibiting Its DNA-Binding Activity | Full Text | References | PDF (880.4 KB)
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Article
Novel Transcription Coactivator Complex Containing Activating Signal Cointegrator 1
Dong-Ju Jung, Hee-Sook Sung, Young-Wha Goo, Hyun Mi Lee, Ok Ku Park, Sung-Yun Jung, Janghoo Lim, Han-Jong Kim, Soo-Kyung Lee, Tae Sung Kim, Jae Woon Lee & Young Chul Lee
Pages: 5203-5211
Published online: 27 Mar 2023
AbstractforNovel Transcription Coactivator Complex Containing Activating Signal Cointegrator 1 | Full Text | References | PDF (534.7 KB)
  • 96 Views
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Article
PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases
Noora Kotaja, Ulla Karvonen, Olli A. Jänne & Jorma J. Palvimo
Pages: 5222-5234
Published online: 27 Mar 2023
AbstractforPIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases | Full Text | References | PDF (894.7 KB)
  • 54 Views
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Gene Expression

Article
Mammalian PRP4 Kinase Copurifies and Interacts with Components of Both the U5 snRNP and the N-CoR Deacetylase Complexes
Graham Dellaire, Evgeny M. Makarov, JeffJ.M. Cowger, Dasa Longman, Heidi G. E. Sutherland, Reinhard Lührmann, Joseph Torchia & Wendy A. Bickmore
Pages: 5141-5156
Published online: 27 Mar 2023
AbstractforMammalian PRP4 Kinase Copurifies and Interacts with Components of Both the U5 snRNP and the N-CoR Deacetylase Complexes | Full Text | References | PDF (846.4 KB)
  • 74 Views
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Article
Lsm Proteins Are Required for Normal Processing of Pre-tRNAs and Their Efficient Association with La-Homologous Protein Lhp1p
Joanna Kufel, Christine Allmang, Loredana Verdone, Jean D. Beggs & David Tollervey
Pages: 5248-5256
Published online: 27 Mar 2023
AbstractforLsm Proteins Are Required for Normal Processing of Pre-tRNAs and Their Efficient Association with La-Homologous Protein Lhp1p | Full Text | References | PDF (371.7 KB)
  • 23 Views
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Dna Dynamics and Chromosome Structure

Article
Association of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair
Kiran N. Mahajan, Stephanie A. Nick McElhinny, Beverly S. Mitchell & Dale A. Ramsden
Pages: 5194-5202
Published online: 27 Mar 2023
AbstractforAssociation of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair | Full Text | References | PDF (448.2 KB)
  • 47 Views
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Errata

Correction
Functional Divergence between Histone Deacetylases in Fission Yeast by Distinct Cellular Localization and In Vivo Specificity
Pages: 5257-5258
Published online: 27 Mar 2023
CitationforFunctional Divergence between Histone Deacetylases in Fission Yeast by Distinct Cellular Localization and In Vivo Specificity | Full Text | PDF (152.5 KB)
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