Molecular and Cellular Biology, Volume 22, Issue 6 (2002)

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Molecular and Cellular Biology, Volume 22, Issue 6 (2002)

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Transcriptional Regulation

Article
Transcription Activator Interactions with Multiple SWI/SNF Subunits
Kristen E. Neely, Ahmed H. Hassan, Christine E. Brown, LeAnn Howe & Jerry L. Workman
Pages: 1615-1625
Published online: 28 Mar 2023
AbstractforTranscription Activator Interactions with Multiple SWI/SNF Subunits | Full Text | References | PDF (468.8 KB)
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Article
Competitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain
Michael D. Ruse Jr., Martin L. Privalsky & Frances M. Sladek
Pages: 1626-1638
Published online: 28 Mar 2023
AbstractforCompetitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain | Full Text | References | PDF (608.6 KB)
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Article
Control of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells
Makoto Akashi, Yoshiki Tsuchiya, Takao Yoshino & Eisuke Nishida
Pages: 1693-1703
Published online: 28 Mar 2023
AbstractforControl of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells | Full Text | References | PDF (559.1 KB)
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Article
Promoter Scanning for Transcription Inhibition with DNA-Binding Polyamides
Jennifer A. Ehley, Christian Melander, David Herman, Eldon E. Baird, Heather A. Ferguson, James A. Goodrich, Peter B. Dervan & Joel M. Gottesfeld
Pages: 1723-1733
Published online: 28 Mar 2023
AbstractforPromoter Scanning for Transcription Inhibition with DNA-Binding Polyamides | Full Text | References | PDF (392 KB)
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Article
Regulation of Nuclear Gamma Interferon Gene Expression by Interleukin 12 (IL-12) and IL-2 Represents a Novel Form of Posttranscriptional Control
Deborah L. Hodge, Alfredo Martinez, John G. Julias, Lynn S. Taylor & Howard A. Young
Pages: 1742-1753
Published online: 28 Mar 2023
AbstractforRegulation of Nuclear Gamma Interferon Gene Expression by Interleukin 12 (IL-12) and IL-2 Represents a Novel Form of Posttranscriptional Control | Full Text | References | PDF (534.5 KB)
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Article
Coupling of Enhancer and Insulator Properties Identified in Two Retrotransposons Modulates Their Mutagenic Impact on Nearby Genes
Caroline Conte, Bernard Dastugue & Chantal Vaury
Pages: 1767-1777
Published online: 28 Mar 2023
AbstractforCoupling of Enhancer and Insulator Properties Identified in Two Retrotransposons Modulates Their Mutagenic Impact on Nearby Genes | Full Text | References | PDF (506.6 KB)
  • 11 Views
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Article
Critical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors
Ari Melnick, Graeme Carlile, K. Farid Ahmad, Chih-Li Kiang, Connie Corcoran, Vivian Bardwell, Gilbert G. Prive & Jonathan D. Licht
Pages: 1804-1818
Published online: 28 Mar 2023
AbstractforCritical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors | Full Text | References | PDF (911 KB)
  • 68 Views
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Article
Precipitous Release of Methyl-CpG Binding Protein 2 and Histone Deacetylase 1 from the Methylated Human Multidrug Resistance Gene (MDR1) on Activation
Assam El-Osta, Phillip Kantharidis, John R. Zalcberg & Alan P. Wolffe
Pages: 1844-1857
Published online: 28 Mar 2023
AbstractforPrecipitous Release of Methyl-CpG Binding Protein 2 and Histone Deacetylase 1 from the Methylated Human Multidrug Resistance Gene (MDR1) on Activation | Full Text | References | PDF (1 MB)
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Article
Binding of the RING Polycomb Proteins to Specific Target Genes in Complex with the grainyhead-Like Family of Developmental Transcription Factors
Annabel Tuckfield, David R. Clouston, Tomasz M. Wilanowski, Lin-Lin Zhao, John M. Cunningham & Stephen M. Jane
Pages: 1936-1946
Published online: 28 Mar 2023
AbstractforBinding of the RING Polycomb Proteins to Specific Target Genes in Complex with the grainyhead-Like Family of Developmental Transcription Factors | Full Text | References | PDF (446.3 KB)
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Cell and Organelle Structure and Assembly

Article
Peroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import
Hidenori Otera, Kiyoko Setoguchi, Maho Hamasaki, Toshitaka Kumashiro, Nobuhiro Shimizu & Yukio Fujiki
Pages: 1639-1655
Published online: 28 Mar 2023
AbstractforPeroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import | Full Text | References | PDF (611 KB)
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Gene Expression

Article
Phosphorylation of Eukaryotic Translation Initiation Factor 4E Is Critical for Growth
Pascal E. D. Lachance, Mathieu Miron, Brian Raught, Nahum Sonenberg & Paul Lasko
Pages: 1656-1663
Published online: 28 Mar 2023
AbstractforPhosphorylation of Eukaryotic Translation Initiation Factor 4E Is Critical for Growth | Full Text | References | PDF (365.6 KB)
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Article
RNA Destabilization by the Granulocyte Colony-Stimulating Factor Stem-Loop Destabilizing Element Involves a Single Stem-Loop That Promotes Deadenylation
R. A. Putland, T. A. Sassinis, J. S. Harvey, P. Diamond, L. S. Coles, C. Y. Brown & G. J. Goodall
Pages: 1664-1673
Published online: 28 Mar 2023
AbstractforRNA Destabilization by the Granulocyte Colony-Stimulating Factor Stem-Loop Destabilizing Element Involves a Single Stem-Loop That Promotes Deadenylation | Full Text | References | PDF (535.4 KB)
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Article
Caspase Cleavage of Initiation Factor 4E-Binding Protein 1 Yields a Dominant Inhibitor of Cap-Dependent Translation and Reveals a Novel Regulatory Motif
Andrew R. Tee & Christopher G. Proud
Pages: 1674-1683
Published online: 28 Mar 2023
AbstractforCaspase Cleavage of Initiation Factor 4E-Binding Protein 1 Yields a Dominant Inhibitor of Cap-Dependent Translation and Reveals a Novel Regulatory Motif | Full Text | References | PDF (448.1 KB)
  • 32 Views
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Article
Requirements of the RNA Polymerase II C-Terminal Domain for Reconstituting Pre-mRNA 3′ Cleavage
Kevin Ryan, Kanneganti G. K. Murthy, Syuzo Kaneko & James L. Manley
Pages: 1684-1692
Published online: 28 Mar 2023
AbstractforRequirements of the RNA Polymerase II C-Terminal Domain for Reconstituting Pre-mRNA 3′ Cleavage | Full Text | References | PDF (438.8 KB)
  • 21 Views
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Cell Growth and Development

Article
The Endothelial Receptor Tyrosine Kinase Tie1 Activates Phosphatidylinositol 3-Kinase and Akt To Inhibit Apoptosis
Christopher D. Kontos, Eugene H. Cha, John D. York & Kevin G. Peters
Pages: 1704-1713
Published online: 28 Mar 2023
AbstractforThe Endothelial Receptor Tyrosine Kinase Tie1 Activates Phosphatidylinositol 3-Kinase and Akt To Inhibit Apoptosis | Full Text | References | PDF (536.9 KB)
  • 44 Views
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Article
Ral-GTPase Influences the Regulation of the Readily Releasable Pool of Synaptic Vesicles
Atsuko Polzin, Michail Shipitsin, Takanori Goi, Larry A. Feig & Timothy J. Turner
Pages: 1714-1722
Published online: 28 Mar 2023
AbstractforRal-GTPase Influences the Regulation of the Readily Releasable Pool of Synaptic Vesicles | Full Text | References | PDF (240.8 KB)
  • 21 Views
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Article
The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia
Konstantin Salnikow, Thomas Kluz, Max Costa, David Piquemal, Zoya N. Demidenko, Keping Xie & Mikhail V. Blagosklonny
Pages: 1734-1741
Published online: 28 Mar 2023
AbstractforThe Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia | Full Text | References | PDF (347.9 KB)
  • 19 Views
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Article
IAP Suppression of Apoptosis Involves Distinct Mechanisms: the TAK1/JNK1 Signaling Cascade and Caspase Inhibition
M. Germana Sanna, Jean da Silva Correia, Odile Ducrey, Jongdae Lee, Ken Nomoto, Nicolas Schrantz, Quinn L. Deveraux & Richard J. Ulevitch
Pages: 1754-1766
Published online: 28 Mar 2023
AbstractforIAP Suppression of Apoptosis Involves Distinct Mechanisms: the TAK1/JNK1 Signaling Cascade and Caspase Inhibition | Full Text | References | PDF (721.9 KB)
  • 59 Views
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Article
A Novel and Conserved Protein-Protein Interaction Domain of Mammalian Lin-2/CASK Binds and Recruits SAP97 to the Lateral Surface of Epithelia
Seonok Lee, Shuling Fan, Olya Makarova, Samuel Straight & Ben Margolis
Pages: 1778-1791
Published online: 28 Mar 2023
AbstractforA Novel and Conserved Protein-Protein Interaction Domain of Mammalian Lin-2/CASK Binds and Recruits SAP97 to the Lateral Surface of Epithelia | Full Text | References | PDF (1.3 MB)
  • 37 Views
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Article
CKA, a Novel Multidomain Protein, Regulates the JUN N-Terminal Kinase Signal Transduction Pathway in Drosophila
Hua-Wei Chen, Maria Julia Marinissen, Su-Wan Oh, Xiu Chen, Michael Melnick, Norbert Perrimon, J. Silvio Gutkind & Steven X. Hou
Pages: 1792-1803
Published online: 28 Mar 2023
AbstractforCKA, a Novel Multidomain Protein, Regulates the JUN N-Terminal Kinase Signal Transduction Pathway in Drosophila | Full Text | References | PDF (945 KB)
  • 39 Views
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Article
The Rab27a/Granuphilin Complex Regulates the Exocytosis of Insulin-Containing Dense-Core Granules
Zhaohong Yi, Hiromi Yokota, Seiji Torii, Takeo Aoki, Masahiro Hosaka, Shengli Zhao, Kuniaki Takata, Toshiyuki Takeuchi & Tetsuro Izumi
Pages: 1858-1867
Published online: 28 Mar 2023
AbstractforThe Rab27a/Granuphilin Complex Regulates the Exocytosis of Insulin-Containing Dense-Core Granules | Full Text | References | PDF (650.2 KB)
  • 79 Views
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Article
Control of DNA Replication and Chromosome Ploidy by Geminin and Cyclin A
Ivailo S. Mihaylov, Takeshi Kondo, Lynn Jones, Sophia Ryzhikov, Junko Tanaka, Jianyu Zheng, Leigh Ann Higa, Naoto Minamino, Lynn Cooley & Hui Zhang
Pages: 1868-1880
Published online: 28 Mar 2023
AbstractforControl of DNA Replication and Chromosome Ploidy by Geminin and Cyclin A | Full Text | References | PDF (883.9 KB)
  • 36 Views
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Article
Heparan Sulfate Proteoglycans Are Ligands for Receptor Protein Tyrosine Phosphatase σ
A. Radu Aricescu, Iain W. McKinnell, Willi Halfter & Andrew W. Stoker
Pages: 1881-1892
Published online: 28 Mar 2023
AbstractforHeparan Sulfate Proteoglycans Are Ligands for Receptor Protein Tyrosine Phosphatase σ | Full Text | References | PDF (945.3 KB)
  • 69 Views
  • 161 CrossRef citations
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Article
Activated Fes Protein Tyrosine Kinase Induces Terminal Macrophage Differentiation of Myeloid Progenitors (U937 Cells) and Activation of the Transcription Factor PU.1
Jynho Kim & Ricardo A. Feldman
Pages: 1903-1918
Published online: 28 Mar 2023
AbstractforActivated Fes Protein Tyrosine Kinase Induces Terminal Macrophage Differentiation of Myeloid Progenitors (U937 Cells) and Activation of the Transcription Factor PU.1 | Full Text | References | PDF (948.3 KB)
  • 28 Views
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Article
BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore
Angela Risso, Enrico Braidot, Maria Concetta Sordano, Angelo Vianello, Francesco Macrì, Barbara Skerlavaj, Margherita Zanetti, Renato Gennaro & Paolo Bernardi
Pages: 1926-1935
Published online: 28 Mar 2023
AbstractforBMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore | Full Text | References | PDF (321 KB)
  • 30 Views
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Article
Diverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity
William J. Hansen, Michael Ohh, Javid Moslehi, Keiichi Kondo, William G. Kaelin & William J. Welch
Pages: 1947-1960
Published online: 28 Mar 2023
AbstractforDiverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity | Full Text | References | PDF (561.3 KB)
  • 15 Views
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Dna Dynamics and Chromosome Structure

Article
Overexpression of c-Myc Alters G1/S Arrest following Ionizing Radiation
Joon-Ho Sheen & Robert B. Dickson
Pages: 1819-1833
Published online: 28 Mar 2023
AbstractforOverexpression of c-Myc Alters G1/S Arrest following Ionizing Radiation | Full Text | References | PDF (1.2 MB)
  • 31 Views
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Article
Hypoxia Links ATR and p53 through Replication Arrest
Ester M. Hammond, Nicholas C. Denko, Mary Jo Dorie, Robert T. Abraham & Amato J. Giaccia
Pages: 1834-1843
Published online: 28 Mar 2023
AbstractforHypoxia Links ATR and p53 through Replication Arrest | Full Text | References | PDF (480.4 KB)
  • 84 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Apolipoprotein J/Clusterin Prevents a Progressive Glomerulopathy of Aging
Mark E. Rosenberg, Richard Girton, David Finkel, David Chmielewski, Arthur Barrie III, David P. Witte, Guang Zhu, John J. Bissler, Judith A. K. Harmony & Bruce J. Aronow
Pages: 1893-1902
Published online: 28 Mar 2023
AbstractforApolipoprotein J/Clusterin Prevents a Progressive Glomerulopathy of Aging | Full Text | References | PDF (1.1 MB)
  • 50 Views
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Article
Activating Transcription Factor 1 and CREB Are Important for Cell Survival during Early Mouse Development
Susanne C. Bleckmann, Julie A. Blendy, Dorothea Rudolph, A. Paula Monaghan, Wolfgang Schmid & Günther Schütz
Pages: 1919-1925
Published online: 28 Mar 2023
AbstractforActivating Transcription Factor 1 and CREB Are Important for Cell Survival during Early Mouse Development | Full Text | References | PDF (944 KB)
  • 45 Views
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