Molecular and Cellular Biology, Volume 24, Issue 17 (2004)

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Molecular and Cellular Biology, Volume 24, Issue 17 (2004)

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Cell Growth and Development

Article
Hyperresponse to T-Cell Receptor Signaling and Apoptosis of Id1 Transgenic Thymocytes
Zengbiao Qi & Xiao-Hong Sun
Pages: 7313-7323
Published online: 27 Mar 2023
AbstractforHyperresponse to T-Cell Receptor Signaling and Apoptosis of Id1 Transgenic Thymocytes | Full Text | References | PDF (510.6 KB)
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Article
The Caenorhabditis elegans Nuclear Receptor Gene nhr-25 Regulates Epidermal Cell Development
Zhe Chen, Dennis J. Eastburn & Min Han
Pages: 7345-7358
Published online: 27 Mar 2023
AbstractforThe Caenorhabditis elegans Nuclear Receptor Gene nhr-25 Regulates Epidermal Cell Development | Full Text | References | PDF (606.2 KB)
  • 82 Views
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Article
Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis
Weicheng Wu, Raymond D. Mosteller & Daniel Broek
Pages: 7359-7369
Published online: 27 Mar 2023
AbstractforSphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis | Full Text | References | PDF (388.5 KB)
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Article
Cell Cycle-Dependent Phosphorylation of C/EBPβ Mediates Oncogenic Cooperativity between C/EBPβ and H-RasV12
Jon D. Shuman, Thomas Sebastian, Philipp Kaldis, Terry D. Copeland, Songyun Zhu, Robert C. Smart & Peter F. Johnson
Pages: 7380-7391
Published online: 27 Mar 2023
AbstractforCell Cycle-Dependent Phosphorylation of C/EBPβ Mediates Oncogenic Cooperativity between C/EBPβ and H-RasV12 | Full Text | References | PDF (476.3 KB)
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Article
Disruption of the SH2-B Gene Causes Age-Dependent Insulin Resistance and Glucose Intolerance
Chaojun Duan, Hongyan Yang, Morris F. White & Liangyou Rui
Pages: 7435-7443
Published online: 27 Mar 2023
AbstractforDisruption of the SH2-B Gene Causes Age-Dependent Insulin Resistance and Glucose Intolerance | Full Text | References | PDF (542.2 KB)
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Article
MUC20 Suppresses the Hepatocyte Growth Factor-Induced Grb2-Ras Pathway by Binding to a Multifunctional Docking Site of Met
Toshio Higuchi, Takuya Orita, Ken Katsuya, Yoshiki Yamasaki, Kiyotaka Akiyama, Huiping Li, Tadashi Yamamoto, Yutaka Saito & Motonao Nakamura
Pages: 7456-7468
Published online: 27 Mar 2023
AbstractforMUC20 Suppresses the Hepatocyte Growth Factor-Induced Grb2-Ras Pathway by Binding to a Multifunctional Docking Site of Met | Full Text | References | PDF (959.3 KB)
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Article
Ubiquitination and Proteolysis of Cancer-Derived Smad4 Mutants by SCFSkp2
Min Liang, Yao-Yun Liang, Katharine Wrighton, Dana Ungermannova, Xiao-Ping Wang, F. Charles Brunicardi, Xuedong Liu, Xin-Hua Feng & Xia Lin
Pages: 7524-7537
Published online: 27 Mar 2023
AbstractforUbiquitination and Proteolysis of Cancer-Derived Smad4 Mutants by SCFSkp2 | Full Text | References | PDF (844.7 KB)
  • 33 Views
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Article
Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues
Paula L. Miliani de Marval, Everardo Macias, Robert Rounbehler, Piotr Sicinski, Hiroaki Kiyokawa, David G. Johnson, Claudio J. Conti & Marcelo L. Rodriguez-Puebla
Pages: 7538-7547
Published online: 27 Mar 2023
AbstractforLack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues | Full Text | References | PDF (677.9 KB)
  • 17 Views
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Article
Separation of Insulin Signaling into Distinct GLUT4 Translocation and Activation Steps
Makoto Funaki, Paramjeet Randhawa & Paul A. Janmey
Pages: 7567-7577
Published online: 27 Mar 2023
AbstractforSeparation of Insulin Signaling into Distinct GLUT4 Translocation and Activation Steps | Full Text | References | PDF (845.4 KB)
  • 19 Views
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Article
Protein Kinase Cα Activates c-Src and Induces Podosome Formation via AFAP-110
Amanda Gatesman, Valerie G. Walker, Joseph M. Baisden, Scott A. Weed & Daniel C. Flynn
Pages: 7578-7597
Published online: 27 Mar 2023
AbstractforProtein Kinase Cα Activates c-Src and Induces Podosome Formation via AFAP-110 | Full Text | References | PDF (2.9 MB)
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Article
Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice
James Hulit, Chenguang Wang, Zhiping Li, Chris Albanese, Mahadev Rao, Dolores Di Vizio, Salimuddin Shah, Stephen W. Byers, Radma Mahmood, Leonard H. Augenlicht, Robert Russell & Richard G. Pestell
Pages: 7598-7611
Published online: 27 Mar 2023
AbstractforCyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice | Full Text | References | PDF (1.1 MB)
  • 21 Views
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Article
Cell Depletion Due to Diphtheria Toxin Fragment A after Cre-Mediated Recombination
Damian Brockschnieder, Corinna Lappe-Siefke, Sandra Goebbels, Michael R. Boesl, Klaus-Armin Nave & Dieter Riethmacher
Pages: 7636-7642
Published online: 27 Mar 2023
AbstractforCell Depletion Due to Diphtheria Toxin Fragment A after Cre-Mediated Recombination | Full Text | References | PDF (721.2 KB)
  • 197 Views
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Article
Ribosomal Protein L23 Activates p53 by Inhibiting MDM2 Function in Response to Ribosomal Perturbation but Not to Translation Inhibition
Mu-Shui Dai, Shelya X. Zeng, Yetao Jin, Xiao-Xin Sun, Larry David & Hua Lu
Pages: 7654-7668
Published online: 27 Mar 2023
AbstractforRibosomal Protein L23 Activates p53 by Inhibiting MDM2 Function in Response to Ribosomal Perturbation but Not to Translation Inhibition | Full Text | References | PDF (720.6 KB)
  • 135 Views
  • 367 CrossRef citations
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Article
Inhibition of HDM2 and Activation of p53 by Ribosomal Protein L23
Aiwen Jin, Koji Itahana, Kevin O'Keefe & Yanping Zhang
Pages: 7669-7680
Published online: 27 Mar 2023
AbstractforInhibition of HDM2 and Activation of p53 by Ribosomal Protein L23 | Full Text | References | PDF (839.6 KB)
  • 52 Views
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Article
Single-Chain Estrogen Receptors (ERs) Reveal that the ERα/β Heterodimer Emulates Functions of the ERα Dimer in Genomic Estrogen Signaling Pathways
Xiaodong Li, Jing Huang, Ping Yi, Robert A. Bambara, Russell Hilf & Mesut Muyan
Pages: 7681-7694
Published online: 27 Mar 2023
AbstractforSingle-Chain Estrogen Receptors (ERs) Reveal that the ERα/β Heterodimer Emulates Functions of the ERα Dimer in Genomic Estrogen Signaling Pathways | Full Text | References | PDF (729.7 KB)
  • 65 Views
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Article
Stabilization of the E3 Ubiquitin Ligase Nrdp1 by the Deubiquitinating Enzyme USP8
Xiuli Wu, Lily Yen, Lisa Irwin, Colleen Sweeney & Kermit L. Carraway III
Pages: 7748-7757
Published online: 27 Mar 2023
AbstractforStabilization of the E3 Ubiquitin Ligase Nrdp1 by the Deubiquitinating Enzyme USP8 | Full Text | References | PDF (401.3 KB)
  • 36 Views
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Dna Dynamics and Chromosome Structure

Article
Saccharomyces cerevisiae Srs2 DNA Helicase Selectively Blocks Expansions of Trinucleotide Repeats
Saumitri Bhattacharyya & Robert S. Lahue
Pages: 7324-7330
Published online: 27 Mar 2023
AbstractforSaccharomyces cerevisiae Srs2 DNA Helicase Selectively Blocks Expansions of Trinucleotide Repeats | Full Text | References | PDF (163.3 KB)
  • 11 Views
  • 65 CrossRef citations
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Article
RNA-Mediated Programming of Developmental Genome Rearrangements in Paramecium tetraurelia
Olivier Garnier, Vincent Serrano, Sandra Duharcourt & Eric Meyer
Pages: 7370-7379
Published online: 27 Mar 2023
AbstractforRNA-Mediated Programming of Developmental Genome Rearrangements in Paramecium tetraurelia | Full Text | References | PDF (330.3 KB)
  • 25 Views
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Article
The B-Subunit of DNA Polymerase α-Primase Associates with the Origin Recognition Complex for Initiation of DNA Replication
Masashi Uchiyama & Teresa S.-F. Wang
Pages: 7419-7434
Published online: 27 Mar 2023
AbstractforThe B-Subunit of DNA Polymerase α-Primase Associates with the Origin Recognition Complex for Initiation of DNA Replication | Full Text | References | PDF (668 KB)
  • 10 Views
  • 21 CrossRef citations
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Article
BRCA2 Is Ubiquitinated In Vivo and Interacts with USP11, a Deubiquitinating Enzyme That Exhibits Prosurvival Function in the Cellular Response to DNA Damage
Alan R. Schoenfeld, Sarah Apgar, Georgia Dolios, Rong Wang & Stuart A. Aaronson
Pages: 7444-7455
Published online: 27 Mar 2023
AbstractforBRCA2 Is Ubiquitinated In Vivo and Interacts with USP11, a Deubiquitinating Enzyme That Exhibits Prosurvival Function in the Cellular Response to DNA Damage | Full Text | References | PDF (715.8 KB)
  • 64 Views
  • 124 CrossRef citations
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Article
Structural Elements Required for Association of the Saccharomyces cerevisiae Telomerase RNA with the Est2 Reverse Transcriptase
Andrew S. Chappell & Victoria Lundblad
Pages: 7720-7736
Published online: 27 Mar 2023
AbstractforStructural Elements Required for Association of the Saccharomyces cerevisiae Telomerase RNA with the Est2 Reverse Transcriptase | Full Text | References | PDF (1.4 MB) | Supplemental
  • 10 Views
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Cell and Organelle Structure and Assembly

Article
Modulation of the Leishmania donovani Peroxin 5 Quaternary Structure by Peroxisomal Targeting Signal 1 Ligands
Kleber P. Madrid, Gregory De Crescenzo, Shengwu Wang & Armando Jardim
Pages: 7331-7344
Published online: 27 Mar 2023
AbstractforModulation of the Leishmania donovani Peroxin 5 Quaternary Structure by Peroxisomal Targeting Signal 1 Ligands | Full Text | References | PDF (327 KB)
  • 12 Views
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Article
Molecular Interactions of Yeast Neo1p, an Essential Member of the Drs2 Family of Aminophospholipid Translocases, and Its Role in Membrane Trafficking within the Endomembrane System
Sidonie Wicky, Heinz Schwarz & Birgit Singer-Krüger
Pages: 7402-7418
Published online: 27 Mar 2023
AbstractforMolecular Interactions of Yeast Neo1p, an Essential Member of the Drs2 Family of Aminophospholipid Translocases, and Its Role in Membrane Trafficking within the Endomembrane System | Full Text | References | PDF (839.9 KB)
  • 72 Views
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Gene Expression

Article
Human U4/U6 snRNP Recycling Factor p110: Mutational Analysis Reveals the Function of the Tetratricopeptide Repeat Domain in Recycling
Jan Medenbach, Silke Schreiner, Sunbin Liu, Reinhard Lührmann & Albrecht Bindereif
Pages: 7392-7401
Published online: 27 Mar 2023
AbstractforHuman U4/U6 snRNP Recycling Factor p110: Mutational Analysis Reveals the Function of the Tetratricopeptide Repeat Domain in Recycling | Full Text | References | PDF (423.9 KB)
  • 23 Views
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Article
Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress
Jaime D. Blais, Vasilisa Filipenko, Meixia Bi, Heather P. Harding, David Ron, Costas Koumenis, Bradly G. Wouters & John C. Bell
Pages: 7469-7482
Published online: 27 Mar 2023
AbstractforActivating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress | Full Text | References | PDF (696.7 KB)
  • 148 Views
  • 317 CrossRef citations
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Article
SMG-1 Is a Phosphatidylinositol Kinase-Related Protein Kinase Required for Nonsense-Mediated mRNA Decay in Caenorhabditis elegans
Andrew Grimson, Sean O'Connor, Carrie Loushin Newman & Philip Anderson
Pages: 7483-7490
Published online: 27 Mar 2023
AbstractforSMG-1 Is a Phosphatidylinositol Kinase-Related Protein Kinase Required for Nonsense-Mediated mRNA Decay in Caenorhabditis elegans | Full Text | References | PDF (318.9 KB)
  • 87 Views
  • 88 CrossRef citations
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Article
Internal Ribosome Entry Site Structural Motifs Conserved among Mammalian Fibroblast Growth Factor 1 Alternatively Spliced mRNAs
Yvan Martineau, Christine Le Bec, Laurent Monbrun, Valérie Allo, Ing-Ming Chiu, Olivier Danos, Hervé Moine, Hervé Prats & Anne-Catherine Prats
Pages: 7622-7635
Published online: 27 Mar 2023
AbstractforInternal Ribosome Entry Site Structural Motifs Conserved among Mammalian Fibroblast Growth Factor 1 Alternatively Spliced mRNAs | Full Text | References | PDF (836.6 KB)
  • 34 Views
  • 48 CrossRef citations
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Article
Glucose Repression of STA1 Expression Is Mediated by the Nrg1 and Sfl1 Repressors and the Srb8-11 Complex
Tae Soo Kim, Sung Bae Lee & Hyen Sam Kang
Pages: 7695-7706
Published online: 27 Mar 2023
AbstractforGlucose Repression of STA1 Expression Is Mediated by the Nrg1 and Sfl1 Repressors and the Srb8-11 Complex | Full Text | References | PDF (483.4 KB)
  • 17 Views
  • 24 CrossRef citations
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Article
GTP Hydrolysis by eRF3 Facilitates Stop Codon Decoding during Eukaryotic Translation Termination
Joe Salas-Marco & David M. Bedwell
Pages: 7769-7778
Published online: 27 Mar 2023
AbstractforGTP Hydrolysis by eRF3 Facilitates Stop Codon Decoding during Eukaryotic Translation Termination | Full Text | References | PDF (233 KB)
  • 104 Views
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Article
Spliced-Leader RNA trans Splicing in a Chordate, Oikopleura dioica, with a Compact Genome
Philippe Ganot, Torben Kallesøe, Richard Reinhardt, Daniel Chourrout & Eric M. Thompson
Pages: 7795-7805
Published online: 27 Mar 2023
AbstractforSpliced-Leader RNA trans Splicing in a Chordate, Oikopleura dioica, with a Compact Genome | Full Text | References | PDF (556.6 KB) | Supplemental
  • 46 Views
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Transcriptional Regulation

Article
Decoding Hematopoietic Specificity in the Helix-Loop-Helix Domain of the Transcription Factor SCL/Tal-1
Thorsten M. Schlaeger, Anna Schuh, Simon Flitter, Andreas Fisher, Hanna Mikkola, Stuart H. Orkin, Paresh Vyas & Catherine Porcher
Pages: 7491-7502
Published online: 27 Mar 2023
AbstractforDecoding Hematopoietic Specificity in the Helix-Loop-Helix Domain of the Transcription Factor SCL/Tal-1 | Full Text | References | PDF (726 KB)
  • 15 Views
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Article
The N-Terminal Regulatory Domain of Stp1p Is Modular and, Fused to an Artificial Transcription Factor, Confers Full Ssy1p-Ptr3p-Ssy5p Sensor Control
Claes Andréasson & Per O. Ljungdahl
Pages: 7503-7513
Published online: 27 Mar 2023
AbstractforThe N-Terminal Regulatory Domain of Stp1p Is Modular and, Fused to an Artificial Transcription Factor, Confers Full Ssy1p-Ptr3p-Ssy5p Sensor Control | Full Text | References | PDF (494.5 KB)
  • 15 Views
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Article
The Thyroid Hormone Receptor Is a Suppressor of ras-Mediated Transcription, Proliferation, and Transformation
Susana García-Silva & Ana Aranda
Pages: 7514-7523
Published online: 27 Mar 2023
AbstractforThe Thyroid Hormone Receptor Is a Suppressor of ras-Mediated Transcription, Proliferation, and Transformation | Full Text | References | PDF (446.7 KB)
  • 22 Views
  • 80 CrossRef citations
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Article
Aberrant Expression of the Transcription Factors Snail and Slug Alters the Response to Genotoxic Stress
Masahiro Kajita, Karissa N. McClinic & Paul A. Wade
Pages: 7559-7566
Published online: 27 Mar 2023
AbstractforAberrant Expression of the Transcription Factors Snail and Slug Alters the Response to Genotoxic Stress | Full Text | References | PDF (363.1 KB)
  • 48 Views
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Article
Role of Atypical Protein Kinase C in Estradiol-Triggered G1/S Progression of MCF-7 Cells
Gabriella Castoria, Antimo Migliaccio, Marina Di Domenico, Maria Lombardi, Antonietta de Falco, Lilian Varricchio, Antonio Bilancio, Maria Vittoria Barone & Ferdinando Auricchio
Pages: 7643-7653
Published online: 27 Mar 2023
AbstractforRole of Atypical Protein Kinase C in Estradiol-Triggered G1/S Progression of MCF-7 Cells | Full Text | References | PDF (575.9 KB)
  • 6 Views
  • 47 CrossRef citations
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Article
Role of an mSin3A-Swi/Snf Chromatin Remodeling Complex in the Feedback Repression of Bile Acid Biosynthesis by SHP
Jongsook Kim Kemper, Hwajin Kim, Ji Miao, Sonali Bhalla & Yangjin Bae
Pages: 7707-7719
Published online: 27 Mar 2023
AbstractforRole of an mSin3A-Swi/Snf Chromatin Remodeling Complex in the Feedback Repression of Bile Acid Biosynthesis by SHP | Full Text | References | PDF (552.2 KB)
  • 14 Views
  • 86 CrossRef citations
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Article
Cross-Regulation among the Polycomb Group Genes in Drosophila melanogaster
Janann Y. Ali & Welcome Bender
Pages: 7737-7747
Published online: 27 Mar 2023
AbstractforCross-Regulation among the Polycomb Group Genes in Drosophila melanogaster | Full Text | References | PDF (239.7 KB)
  • 15 Views
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Article
Jun Blockade of Erythropoiesis: Role for Repression of GATA-1 by HERP2
Kamaleldin E. Elagib, Mang Xiao, Isa M. Hussaini, Lorrie L. Delehanty, Lisa A. Palmer, Frederick K. Racke, Michael J. Birrer, Ganapath Shanmugasundaram, Michael A. McDevitt & Adam N. Goldfarb
Pages: 7779-7794
Published online: 27 Mar 2023
AbstractforJun Blockade of Erythropoiesis: Role for Repression of GATA-1 by HERP2 | Full Text | References | PDF (721.9 KB)
  • 20 Views
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Article
NF-κB and AP-1 Connection: Mechanism of NF-κB-Dependent Regulation of AP-1 Activity
Shuichi Fujioka, Jiangong Niu, Christian Schmidt, Guido M. Sclabas, Bailu Peng, Tadashi Uwagawa, Zhongkui Li, Douglas B. Evans, James L. Abbruzzese & Paul J. Chiao
Pages: 7806-7819
Published online: 27 Mar 2023
AbstractforNF-κB and AP-1 Connection: Mechanism of NF-κB-Dependent Regulation of AP-1 Activity | Full Text | References | PDF (867.6 KB)
  • 250 Views
  • 312 CrossRef citations
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Neonatal Lethality, Dwarfism, and Abnormal Brain Development in Dmbx1 Mutant Mice
Akihira Ohtoshi & Richard R. Behringer
Pages: 7548-7558
Published online: 27 Mar 2023
AbstractforNeonatal Lethality, Dwarfism, and Abnormal Brain Development in Dmbx1 Mutant Mice | Full Text | References | PDF (1.3 MB)
  • 16 Views
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Article
Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy
Markos Leggas, Masashi Adachi, George L. Scheffer, Daxi Sun, Peter Wielinga, Guoqing Du, Kelly E. Mercer, Yanli Zhuang, John C. Panetta, Brad Johnston, Rik J. Scheper, Clinton F. Stewart & John D. Schuetz
Pages: 7612-7621
Published online: 27 Mar 2023
AbstractforMrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy | Full Text | References | PDF (869.4 KB)
  • 115 Views
  • 324 CrossRef citations
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Article
Mice with Deficiency of G Protein γ3 Are Lean and Have Seizures
William F. Schwindinger, Kathryn E. Giger, Kelly S. Betz, Anna M. Stauffer, Elaine M. Sunderlin, Laura J. Sim-Selley, Dana E. Selley, Sarah K. Bronson & Janet D. Robishaw
Pages: 7758-7768
Published online: 27 Mar 2023
AbstractforMice with Deficiency of G Protein γ3 Are Lean and Have Seizures | Full Text | References | PDF (518.6 KB)
  • 20 Views
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Author's Correction

Correction
Histone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast
Page: 7820
Published online: 27 Mar 2023
CitationforHistone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast | Full Text | PDF (16.9 KB)
  • 92 Views
  • 1 CrossRef citations
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