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Volume 10, Issue 1

Statistics in Biopharmaceutical Research

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Statistics in Biopharmaceutical Research, Volume 10, Issue 1 (2018)

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Statistics in Biopharmaceutical Research, Volume 10, Issue 1 (2018)

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Original Articles

Article

An Efficient Procedure for Calculating Sample Size Through Statistical Simulations

Kazushi Maruo, Keisuke Tada, Ryota Ishii & Masahiko Gosho

Pages: 1-8

Published online: 26 Mar 2018

AbstractforAn Efficient Procedure for Calculating Sample Size Through Statistical Simulations | Full Text | References | PDF (1.6 MB)

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Article

Novel Superiority Tests for Anti-Infective Drug Trials: Three Examples

Erica Brittain, Dean Follmann & Gyan Joshi

Pages: 9-17

Published online: 26 Mar 2018

AbstractforNovel Superiority Tests for Anti-Infective Drug Trials: Three Examples | Full Text | References | PDF (1.8 MB)

252 Views
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Article

Step-Down Parametric Procedures for Testing Correlated Endpoints in a Group-Sequential Trial

Yiyong Fu

Pages: 18-25

Published online: 26 Mar 2018

AbstractforStep-Down Parametric Procedures for Testing Correlated Endpoints in a Group-Sequential Trial | Full Text | References | PDF (785.7 KB) | Supplemental

2437 Views
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Open Access

Article

The Overlooked Importance of Constants Added in Log Transformation of Independent Variables with Zero Values: A Proposed Approach for Determining an Optimal Constant

John Paul Ekwaru & Paul J Veugelers

Pages: 26-29

Published online: 26 Mar 2018

AbstractforThe Overlooked Importance of Constants Added in Log Transformation of Independent Variables with Zero Values: A Proposed Approach for Determining an Optimal Constant | Full Text | References | PDF (1.1 MB)

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Article

Estimation of Standard Deviation for a Log-Transformed Variable Based on Summary Statistics in the Original Scale

Hui Quan, Juan Zhang, Dongli Zhou & Deborah Dukovic

Pages: 30-38

Published online: 26 Mar 2018

AbstractforEstimation of Standard Deviation for a Log-Transformed Variable Based on Summary Statistics in the Original Scale | Full Text | References | PDF (643.6 KB)

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Article

Sample Size for Multiple Hypothesis Testing in Biosimilar Development

Johanna Mielke, Byron Jones, Bernd Jilma & Franz König

Pages: 39-49

Published online: 26 Mar 2018

AbstractforSample Size for Multiple Hypothesis Testing in Biosimilar Development | Full Text | References | PDF (772.3 KB) | Supplemental

956 Views
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Article

Practical Recommendations for Regional Consistency Evaluation in Multi-Regional Clinical Trials with Different Endpoints

Zhaoyang Teng, Jianchang Lin & Bin Zhang

Pages: 50-56

Published online: 26 Mar 2018

AbstractforPractical Recommendations for Regional Consistency Evaluation in Multi-Regional Clinical Trials with Different Endpoints | Full Text | References | PDF (780.4 KB)

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Article

The Role of Multiple Imputation in Noninferiority Trials for Binary Outcomes

Ilya Lipkovich & Brian L. Wiens

Pages: 57-69

Published online: 26 Mar 2018

AbstractforThe Role of Multiple Imputation in Noninferiority Trials for Binary Outcomes | Full Text | References | PDF (795.9 KB)

237 Views
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Corrigendum

Correction

Editorial Board for The 2015 International Society for Biopharmaceutical Statistics (ISBS) and DIA China Special Issue

Page: 70

Published online: 26 Mar 2018

CitationforEditorial Board for The 2015 International Society for Biopharmaceutical Statistics (ISBS) and DIA China Special Issue | Full Text | PDF (130.9 KB)

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Free Access

Indices

Index

Editorial Board

Page: ebi

Published online: 26 Mar 2018

CitationforEditorial Board | Full Text | PDF (19.8 KB)

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