849
Views
59
CrossRef citations to date
0
Altmetric
Research Article

In-vitro antibacterial and cytotoxic activity of cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes of the antibiotic drug cephalothin (Keflin)

&
Pages 463-468 | Received 15 Apr 2005, Accepted 23 May 2005, Published online: 04 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (17)

Taruna Singh, Sheikh Shreaz & Athar Adil Hashmi. (2013) Synthesis of Sunflower Oil Based Bimetallic Polymer and Its Antifungal Studies. International Journal of Polymeric Materials and Polymeric Biomaterials 62:12, pages 653-662.
Read now
Zahid H. Chohan & Hazoor A. Shad. (2012) Metal-based new sulfonamides: Design, synthesis, antibacterial, antifungal, and cytotoxic properties. Journal of Enzyme Inhibition and Medicinal Chemistry 27:3, pages 403-412.
Read now
Zahid H. Chohan, Hazoor A. Shad & Claudiu T. Supuran. (2012) Synthesis, characterization and biological studies of sulfonamide Schiff’s bases and some of their metal derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 27:1, pages 58-68.
Read now
Zahid H. Chohan & Sajjad H. Sumrra. (2010) Some biologically active oxovanadium(IV) complexes of triazole derived Schiff bases: their synthesis, characterization and biological properties. Journal of Enzyme Inhibition and Medicinal Chemistry 25:5, pages 599-607.
Read now
Mukhtiar Hussain, Muhammad Sheeraz Ahmad, Muhammad Hanif, Saqib Ali & Bushra Mirza. (2010) Structure elucidation and inhibitory effects of self-assembled organotin(IV) esters of p-tolyl acetic acid on bacterial, fungal, brine shrimp, and potato tumor cells. Drug and Chemical Toxicology 33:2, pages 183-192.
Read now
Gangadhar B. Bagihalli, Prema S. Badami & Sangamesh A. Patil. (2009) Synthesis, spectral characterization and in vitro biological studies of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases. Journal of Enzyme Inhibition and Medicinal Chemistry 24:2, pages 381-394.
Read now
Pramod B. Pansuriya, Mohan N. Patel, Mehul R. Chhasatia, Pinakin Dhandhukia & Vasudev Thakkar. (2008) Synthesis, characterization, biocidal and nuclease activity of some coordination compounds. Journal of Coordination Chemistry 61:20, pages 3336-3349.
Read now
Zahid H. Chohan & Hazoor A. Shad. (2008) Structural elucidation and biological significance of 2-hydroxy-1-naphthaldehyde derived sulfonamides and their first row d-transition metal chelates. Journal of Enzyme Inhibition and Medicinal Chemistry 23:3, pages 369-379.
Read now
Zahid H. Chohan & Claudiu T. Supuran. (2008) Structure and biological properties of first row d-transition metal complexes with N-substituted sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 23:2, pages 240-251.
Read now
Pramod B. Pansuriya, Pinakin Dhandhukia, Vasudev Thakkar & Mohan N. Patel. (2007) Synthesis, spectroscopic and biological aspects of iron(II) complexes. Journal of Enzyme Inhibition and Medicinal Chemistry 22:4, pages 477-487.
Read now
M. I. Khan, Musa Kaleem Baloch & Muhammad Ashfaq. (2007) Spectral analysis and in vitro cytotoxicity profiles of novel organotin(IV) esters of 2-maleimidopropanoic acid. Journal of Enzyme Inhibition and Medicinal Chemistry 22:3, pages 343-350.
Read now
Zahid H. Chohan, Ali U. Shaikh, Muhammad M. Naseer & Claudiu T. Supuran. (2006) In-vitro antibacterial, antifungal and cytotoxic properties of metal-based furanyl derived sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 21:6, pages 771-781.
Read now

Articles from other publishers (42)

A. Salomanravi, P. Muthuselvan, Francisxavier Paularokiadoss & Thayalaraj Christopher Jeyakumar. (2023) Synthesis, structure, DNA/BSA binding, antibacterial and molecular docking studies of tetradentate ONNO schiff base metal complexes. Journal of Molecular Structure 1287, pages 135570.
Crossref
Subhash, Jyoti & Ashu Chaudhary. (2023) Synthesis, spectroscopic characterization, in vitro cytotoxic, antimicrobial and antioxidant studies of Co(II) complexes bearing pyridine-based macrocyclic ligands with density function theory (DFT) and molecular docking investigations. Research on Chemical Intermediates.
Crossref
Eman H. Al-Thubaiti, Samy M. El-Megharbel, Bander Albogami & Reham Z. Hamza. (2022) Synthesis, Spectroscopic, Chemical Characterizations, Anticancer Capacities against HepG-2, Antibacterial and Antioxidant Activities of Cefotaxime Metal Complexes with Ca(II), Cr(III), Zn(II), Cu(II) and Se(IV). Antibiotics 11:7, pages 967.
Crossref
Tran X. N. Huy, Trang T. Nguyen, Alisha W. B. Reyes, Heejin Kim, WonGi Min, Hu J. Lee, John H. Lee & Suk Kim. (2022) Cobalt (II) Chloride Regulates the Invasion and Survival of Brucella abortus 544 in RAW 264.7 Cells and B6 Mice. Pathogens 11:5, pages 596.
Crossref
Pooja Sethi, Rajshree Khare, Renuka Choudhary & Simrat Kaur. (2022) Mechanochemical Synthesis of Biologically Active Transition Metal Complexes of 1H-4,4,6-Trimethyl-3,4-dihydropyrimidine-2-thione. Asian Journal of Chemistry 34:5, pages 1157-1164.
Crossref
Mirjana Antonijević Nikolić, Katalin Mészáros Szécsényi, Branka Dražić, Marko V. Rodić, Vojislav Stanić & Slađana Tanasković. (2021) Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior. Journal of Molecular Structure 1236, pages 130133.
Crossref
Arbia Ben Khelifa, Khaireddine Ezzayani, Mouhieddinne Guergueb, Frederique Loiseau, Eric Saint-Aman & Habib Nasri. (2021) Synthesis, molecular structure, spectroscopic characterization and antibacterial activity of the pyrazine magnesium porphyrin coordination polymer. Journal of Molecular Structure 1227, pages 129508.
Crossref
Khaireddine Ezzayani, Arbia Ben Khelifa, Fadia Ben Taheur, Mouhieddinne Guergueb, Anissa Mansour, Jean-Claude Daran & Habib Nasri. (2021) Building-up novel coordination polymer with magnesium porphyrin: Synthesis, molecular structure, photophysical properties and spectroscopic characterization. Potential application as antibacterial agent. Inorganica Chimica Acta 514, pages 119960.
Crossref
Ronok Zahan, Sinthyia Ahmed, Tahmida Sharmin, Mohammad A. Halim, Md. Sifat Rahi, Md. Chanmiya Sheikh, Ryuta Miyatake, Ennio Zangrando, Tarannum Naz, Md. Al‐Amin‐Al‐Azadul Islam & Md Abu Reza. (2020) Synthesis of bis[benzyl‐ N′ ‐hydrazinecarbodithioato‐ κ 2 N′ , S ]nickel(II) complex as a novel lead molecule for cancer treatment . Applied Organometallic Chemistry 35:1.
Crossref
Lekaa K. Abdul Karem & Taghreed.H. Al-Noor. (2020) Mixed Ligand Complexes of Schiff Base and Nicotinamide: Synthesis, Characterization and Antimicrobial Activities. Journal of Physics: Conference Series 1660:1, pages 012094.
Crossref
Aeysha Sultan, Mian Habib Ur Rehman, Noreen Sajjad, Ali Irfan, Irfan Ullah, Muhammad Mustaqeem, Muhammad Saleem, Syeda Laila Rubab, Muhammad Rafiq, Muhammad Khalid, Katarzyna Kotwica-Mojzych & Mariusz Mojzych. (2020) A facile sonochemical protocol for synthesis of 3-amino- and 4-amino-1,2,4-triazole derived Schiff bases as potential antibacterial agents. PLOS ONE 15:6, pages e0229891.
Crossref
Somasundaram Hemalatha, Jeyaprakash Dharmaraja, Sutha Shobana, Paramasivam Subbaraj, Thirugnanasamy Esakkidurai & Natarajan Raman. (2020) Chemical and pharmacological aspects of novel hetero MLB complexes derived from NO2 type Schiff base and N2 type 1,10-phenanthroline ligands. Journal of Saudi Chemical Society 24:1, pages 61-80.
Crossref
Venkatanarasimha R Chelli & Animes K Golder. (2019) One pot green synthesis of Pt, Co and Pt@Co core-shell nanoparticles using Sechium edule . Journal of Chemical Technology & Biotechnology 94:3, pages 911-918.
Crossref
G. S. Senthilkumar, M. Sankarganesh, J. Rajesh, C. Vedhi & J. Dhaveethu Raja. (2017) Synthesis, spectral characterization, DNA interaction, antioxidant, and antimicrobial studies of new water soluble metal(II) complexes of morpholine based ligand. Russian Journal of General Chemistry 87:11, pages 2654-2663.
Crossref
Moamen S. Refat, T. Sharshar, K.M. Elsabawy, Mohamed Y. El-Sayed & Abdel Majid A. Adam. (2017) Synthesis of new drug model has an effective antimicrobial and antitumors by combination of cephalosporin antibiotic drug with silver(I) ion in nano scale range: Chemical, physical and biological studies. Journal of Molecular Liquids 244, pages 169-181.
Crossref
Kiran Singh, Yogender Kumar, Parvesh Puri, Chetan Sharma & Kamal Rai Aneja. (2017) Antimicrobial, spectral and thermal studies of divalent cobalt, nickel, copper and zinc complexes with triazole Schiff bases. Arabian Journal of Chemistry 10, pages S978-S987.
Crossref
Salem Saïd, Rihab Ben Abdallah Kolsi & Houcine Naïli. (2016) Structural features, thermal behavior and biological activities of two new organically templated (CoII, NiII) sulfates. Journal of Organometallic Chemistry 809, pages 45-56.
Crossref
Jing-Wei Zheng & Lin Ma. (2016) Metal complexes of anthranilic acid derivatives: A new class of non-competitive α-glucosidase inhibitors. Chinese Chemical Letters 27:5, pages 627-630.
Crossref
S. Jone Kirubavathy, R. Velmurugan, R. Karvembu, N. S. P. Bhuvanesh, K. Parameswari & S. Chitra. (2015) Synthesis, structure, and pharmacological evaluation of Co(III) complex containing tridentate Schiff base ligand. Russian Journal of Coordination Chemistry 41:5, pages 345-352.
Crossref
Sutha Shobana, Perumal Subramaniam, Liviu Mitu, Jeyaprakash Dharmaraja & Sundaram Arvind Narayan. (2015) Synthesis, structural elucidation, biological, antioxidant and nuclease activities of some 5-Fluorouracil–amino acid mixed ligand complexes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 134, pages 333-344.
Crossref
Aurora Reiss, Mariana Carmen Chifiriuc, Emilia Amzoiu & Cezar Ionuţ Spînu. (2014) Transition Metal(II) Complexes with Cefotaxime-Derived Schiff Base: Synthesis, Characterization, and Antimicrobial Studies. Bioinorganic Chemistry and Applications 2014, pages 1-17.
Crossref
Jeyaprakash Dharmaraja, Thirugnanasamy Esakkidurai, Paramasivam Subbaraj & Sutha Shobana. (2013) Mixed ligand complex formation of 2-aminobenzamide with Cu(II) in the presence of some amino acids: Synthesis, structural, biological, pH-metric, spectrophotometric and thermodynamic studies. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 114, pages 607-621.
Crossref
Amanda Alonso, Xavier Muñoz-Berbel, Núria Vigués, Rosalía Rodríguez-Rodríguez, Jorge Macanás, Maria Muñoz, Jordi Mas & Dmitri N. Muraviev. (2013) Superparamagnetic Ag@Co-Nanocomposites on Granulated Cation Exchange Polymeric Matrices with Enhanced Antibacterial Activity for the Environmentally Safe Purification of Water. Advanced Functional Materials 23:19, pages 2450-2458.
Crossref
V. G. Alekseev. (2012) Metal complexes of penicillins and cephalosporins (Review). Pharmaceutical Chemistry Journal 45:11, pages 679-697.
Crossref
Robert C. Dunbar, Jos Oomens, Galina Orlova & Diethard K. Bohme. (2011) IRMPD spectroscopic investigation of gas-phase complexes of deprotonated penicillin G with Ba2+, Zn2+ and Cd2+. International Journal of Mass Spectrometry 308:2-3, pages 330-337.
Crossref
Zahid H. Chohan & Hazoor A. Shad. (2011) Sulfonamide-derived compounds and their transition metal complexes: synthesis, biological evaluation and X-ray structure of 4-bromo-2-[(E)-{4-[(3,4-dimethylisoxazol-5 yl)sulfamoyl]phenyl} iminiomethyl] phenolate. Applied Organometallic Chemistry 25:8, pages 591-600.
Crossref
Mohan Patel, Mehul Chhasatia & Bhupesh Bhatt. (2010) In vitro bacteriostatic and DNA interaction studies of drug-based mixed-ligand complexes of cobalt(II). Medicinal Chemistry Research 20:2, pages 220-230.
Crossref
Kiran Singh, Yogender Kumar, Parvesh Puri, Chetan Sharma & Kamal Rai Aneja. (2011) Metal-Based Biologically Active Compounds: Synthesis, Spectral, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes of Triazole-Derived Schiff Bases. Bioinorganic Chemistry and Applications 2011, pages 1-10.
Crossref
Neil Poulter, Matthew Donaldson, Geraldine Mulley, Luis Duque, Nicholas Waterfield, Alex G. Shard, Steve Spencer, A. Tobias A. Jenkins & Andrew L. Johnson. (2011) Plasma deposited metal Schiff-base compounds as antimicrobials. New Journal of Chemistry 35:7, pages 1477.
Crossref
Zahid H. Chohan, Hazoor A. Shad, Moulay H. Youssoufi & Taibi Ben Hadda. (2010) Some new biologically active metal-based sulfonamide. European Journal of Medicinal Chemistry 45:7, pages 2893-2901.
Crossref
Reena Jain & N .Κ. Kaushik. (2010) Synthesis, Spectral and Antibacterial Studies of Some Organotin (IV) Complexes With Semi-Synthetic Penicillins. Main Group Metal Chemistry 33:1-2.
Crossref
Zahid H. Chohan, Hazoor A. Shad & Faiz-ul-Hassan Nasim. (2009) Synthesis, characterization and biological properties of sulfonamide-derived compounds and their transition metal complexes. Applied Organometallic Chemistry 23:8, pages 319-328.
Crossref
Zahid H. Chohan. (2008) Metal-based antibacterial and antifungal sulfonamides: synthesis, characterization, and biological properties. Transition Metal Chemistry 34:2, pages 153-161.
Crossref
Zahid H. Chohan & Sajjad H. Sumrra. (2009) Synthesis, characterization and biological studies of oxovanadium(IV) complexes with triazole-derived Schiff bases. Applied Organometallic Chemistry, pages n/a-n/a.
Crossref
Muhammad S Ahmad, Bushra Mirza, Mukhtiar Hussain, Muhammad Hanif, Saqib Ali, Michael J Walsh & Francis L Martin. (2008) ATR-FTIR spectroscopy detects alterations induced by organotin(IV) carboxylates in MCF-7 cells at sub-cytotoxic/-genotoxic concentrations. PMC Biophysics 1:1.
Crossref
Muhammad Sheeraz Ahmad, Mukhtiar Hussain, Muhammad Hanif, Saqib Ali, Mazhar Qayyum & Bushra Mirza. (2008) Di- and Triorganotin(IV) Esters of 3,4-Methylenedioxyphenylpropenoic Acid: Synthesis, Spectroscopic Characterization and Biological Screening for Antimicrobial, Cytotoxic and Antitumor Activities. Chemical Biology & Drug Design 71:6, pages 568-576.
Crossref
Zahid H. Chohan & Muhammad M. Naseer. (2007) Organometallic based biologically active compounds: synthesis of mono‐ and di‐ethanolamine derived ferrocenes with antibacterial, antifungal and cytotoxic properties. Applied Organometallic Chemistry 21:12, pages 1005-1012.
Crossref
Pramod B. Pansuriya & Mohan N. Patel. (2007) Synthesis, spectral, thermal, DNA interaction and antimicrobial properties of novel Cu(II) heterochelates. Applied Organometallic Chemistry 21:9, pages 739-749.
Crossref
Zahid H. Chohan & Muhammad M. Naseer. (2007) Metal‐based sulfonamides: synthesis, characterization, antibacterial, antifungal and cytotoxic properties of pyrrolyl‐ and thienyl‐derived compounds. Applied Organometallic Chemistry 21:9, pages 728-738.
Crossref
Zahid H. Chohan, M. Arif & M. Sarfraz. (2007) Metal‐based antibacterial and antifungal amino acid derived Schiff bases: their synthesis, characterization and in vitro biological activity . Applied Organometallic Chemistry 21:4, pages 294-302.
Crossref
Zahid H. Chohan, Ali U. Shaikh & Muhammad M. Naseer. (2006) Metal‐based isatin‐bearing sulfonamides: their synthesis, characterization and biological properties. Applied Organometallic Chemistry 20:11, pages 729-739.
Crossref
Zahid H. Chohan, M. Arif, Muhammad A. Akhtar & Claudiu T. Supuran. (2006) Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes with Amino Acid-Derived Compounds. Bioinorganic Chemistry and Applications 2006, pages 1-13.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.