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Original Article

Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder

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Pages 1303-1318 | Accepted 28 Mar 2007, Published online: 27 Apr 2007

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Benchalak Maneeton, Narong Maneeton, Surinporn Likhitsathian, Pakapan Woottiluk, Punjaree Wiriyacosol, Vudhichai Boonyanaruthee & Manit Srisurapanont. (2018) Escitalopram vs duloxetine in acute treatment of major depressive disorder: meta-analysis and systematic review. Neuropsychiatric Disease and Treatment 14, pages 1953-1961.
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Lanny Bochsler, James S Olver & Trevor R Norman. (2011) Duloxetine in the acute and continuation treatment of major depressive disorder. Expert Review of Neurotherapeutics 11:11, pages 1525-1539.
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Chi-Un Pae, Patrick Luyten, David M. Marks, Changsu Han, Sung-Hwan Park, Ashwin A. Patkar, Prakash S. Masand & Boudewijn Van Houdenhove. (2008) The relationship between fibromyalgia and major depressive disorder: a comprehensive review. Current Medical Research and Opinion 24:8, pages 2359-2371.
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Cyril Höschl & Jaromír Švestka. (2008) Escitalopram for the treatment of major depression and anxiety disorders. Expert Review of Neurotherapeutics 8:4, pages 537-552.
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Norbert Müller, Rebecca Schennach, Michael Riedel & Hans-Jürgen Möller. (2008) Duloxetine in the treatment of major psychiatric and neuropathic disorders. Expert Review of Neurotherapeutics 8:4, pages 527-536.
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Carlos Blanco, Mayumi Okuda, Hannah Rosenthal & Roberto Lewis-Fernandez. (2008) Duloxetine in the treatment of major depression and other psychiatric disorders. Expert Review of Clinical Pharmacology 1:2, pages 195-205.
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Daniela Rodrigues-Amorim, José Manuel Olivares, Carlos Spuch & Tania Rivera-Baltanás. (2020) A Systematic Review of Efficacy, Safety, and Tolerability of Duloxetine. Frontiers in Psychiatry 11.
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Guanjun Li, Yifeng Shen, Jianfeng Luo & Huafang Li. (2017) Efficacy of escitalopram monotherapy in the treatment of major depressive disorder. Medicine 96:39, pages e8142.
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Arash Mowla, Sanaz Boostani & Seyed Ali Dastgheib. (2016) Duloxetine Augmentation in Resistant Obsessive-Compulsive Disorder. Journal of Clinical Psychopharmacology 36:6, pages 720-723.
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Arash Mowla, Seyed Ali Dastgheib & Leila Razeghian Jahromi. (2016) Comparing the Effects of Sertraline with Duloxetine for Depression Severity and Symptoms: A Double-Blind, Randomized Controlled Trial. Clinical Drug Investigation 36:7, pages 539-543.
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Leslie Citrome. (2016) Vortioxetine for major depressive disorder: An indirect comparison with duloxetine, escitalopram, levomilnacipran, sertraline, venlafaxine, and vilazodone, using number needed to treat, number needed to harm, and likelihood to be helped or harmed. Journal of Affective Disorders 196, pages 225-233.
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E. Harada, M. Kato, S. Fujikoshi, M. M. Wohlreich, L. Berggren & H. Tokuoka. (2015) Changes in energy during treatment of depression: an analysis of duloxetine in double‐blind placebo‐controlled trials. International Journal of Clinical Practice 69:10, pages 1139-1148.
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J. Craig Nelson. (2011) Effects of Baseline Depression Severity on Remission Rates With Duloxetine and Placebo in Anxious and Nonanxious Patients With Major Depression. Journal of Clinical Psychopharmacology 31:5, pages 682-684.
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Andrea Pierò & Enrica Locati. (2011) An open, non‐randomised comparison of escitalopram and duloxetine for the treatment of subjects with Generalized Anxiety Disorder. Human Psychopharmacology: Clinical and Experimental 26:1, pages 63-71.
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Karly P. Garnock-Jones & Paul L. McCormack. (2010) Escitalopram. CNS Drugs 24:9, pages 769-796.
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Brian Leonard & David Taylor. (2010) Review: Escitalopram—translating molecular properties into clinical benefit: reviewing the evidence in major depression. Journal of Psychopharmacology 24:8, pages 1143-1152.
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J. Craig Nelson. (2010) Anxiety does not predict response to duloxetine in major depression: results of a pooled analysis of individual patient data from 11 placebo-controlled trials. Depression and Anxiety 27:1, pages 12-18.
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Gerald Gartlehner, Kylie Thaler, Richard A. Hansen & Bradley N. Gaynes. (2009) The General and Comparative Efficacy and Safety of Duloxetine in Major Depressive Disorder. Drug Safety 32:12, pages 1159-1173.
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Susan G. Kornstein, Dayong Li, Yongcai Mao, Sara Larsson, Henning F. Andersen & George I. Papakostas. (2014) Escitalopram Versus SNRI Antidepressants in the Acute Treatment of Major Depressive Disorder: Integrative Analysis of Four Double-Blind, Randomized Clinical Trials . CNS Spectrums 14:6, pages 326-333.
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Sylvia ZerjavGordon TseMichael J.W. Scott. (2009) Review of Duloxetine and Venlafaxine in Depression. Canadian Pharmacists Journal / Revue des Pharmaciens du Canada 142:3, pages 144-152.e6.
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Katsumasa Muneoka. (2009) Pharmacotherapy of Major Depressive Disorder: Focus on Duloxetine. Clinical Medicine. Therapeutics 1, pages CMT.S1988.
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Ripu D. Jindal. (2009) Insomnia in Patients with Depression. CNS Drugs 23:4, pages 309-329.
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Lawrence D. Ginsberg. (2014) Impact of Drug Tolerability on the Selection of Antidepressant Treatment in Patients With Major Depressive Disorder. CNS Spectrums 14:S12, pages 8-14.
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A. Prakash, R. C. Risser & C. H. Mallinckrodt. (2008) The impact of analytic method on interpretation of outcomes in longitudinal clinical trials. International Journal of Clinical Practice 62:8, pages 1147-1158.
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Anita Clayton, Susan Kornstein, Apurva Prakash, Craig Mallinckrodt & Madelaine Wohlreich. (2007) ORIGINAL RESEARCH—PSYCHOLOGY: Changes in Sexual Functioning Associated with Duloxetine, Escitalopram, and Placebo in the Treatment of Patients with Major Depressive Disorder. The Journal of Sexual Medicine 4:4, pages 917-929.
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