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Review

Electroporation-based DNA immunisation: translation to the clinic

, MD PhD, , PhD &
Pages 1647-1664 | Published online: 26 Oct 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Lucyna Cova. (2017) Present and future DNA vaccines for chronic hepatitis B treatment. Expert Opinion on Biological Therapy 17:2, pages 185-195.
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Maarten A Ligtenberg, Nicole Rojas-Colonelli, Rolf Kiessling & Alvaro Lladser. (2013) NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses. Human Vaccines & Immunotherapeutics 9:10, pages 2189-2195.
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Sylvia van Drunen Littel-van den Hurk & D Hannaman. (2010) Electroporation for DNA immunization: clinical application. Expert Review of Vaccines 9:5, pages 503-517.
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Lesley C Dupuy & Connie S Schmaljohn. (2009) DNA vaccines for biodefense. Expert Review of Vaccines 8:12, pages 1739-1754.
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M Golzio, S Mazeres & J Teissie. (2009) Electrodes for in vivo localised subcutaneous electropulsation and associated drug and nucleic acid delivery. Expert Opinion on Drug Delivery 6:12, pages 1323-1331.
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R. L. Metheringham, V. A. Pudney, B. Gunn, M. Towey, I. Spendlove & L. G. Durrant. (2009) Antibodies designed as effective cancer vaccines. mAbs 1:1, pages 71-85.
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Pieranna Chiarella, Emanuela Massi, Mariangela De Robertis, Annarita Sibilio, Paola Parrella, Vito Michele Fazio & Emanuela Signori. (2008) Electroporation of skeletal muscle induces danger signal release and antigen-presenting cell recruitment independently of DNA vaccine administration. Expert Opinion on Biological Therapy 8:11, pages 1645-1657.
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Thomas M Luby. (2008) Targeting cytochrome P450 CYP1B1 with a therapeutic cancer vaccine. Expert Review of Vaccines 7:7, pages 995-1003.
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Duarte Miguel F. Prazeres & Gabriel A. Monteiro. (2014) Plasmid Biopharmaceuticals. Microbiology Spectrum 2:6.
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Lei Tan, HuiJun Lu, Dan Zhang, KaiYan Wang, MingYao Tian, CunXia Liu, YanYu LiU, Bo Hu & NingYi Jin. (2011) Efficacy of seasonal pandemic influenza hemagglutinin DNA vaccines delivered by electroporation against aseasonal H1N1 virus challenge in mice. Science China Life Sciences 54:4, pages 293-299.
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Karen E. Dolter, Claire F. Evans, Barry Ellefsen, Juwan Song, Mar Boente-Carrera, Roselle Vittorino, Talia J. Rosenberg, Drew Hannaman & Sandhya Vasan. (2011) Immunogenicity, safety, biodistribution and persistence of ADVAX, a prophylactic DNA vaccine for HIV-1, delivered by in vivo electroporation. Vaccine 29:4, pages 795-803.
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Sandhya Vasan, Sarah J. Schlesinger, Yaoxing Huang, Arlene Hurley, Angela Lombardo, Zhiwei Chen, Soe Than, Phumla Adesanya, Catherine Bunce, Mark Boaz, Rosanne Boyle, Eddy Sayeed, Lorna Clark, Daniel Dugin, Claudia Schmidt, Yang Song, Laura Seamons, Len Dally, Martin Ho, Carol Smith, Martin Markowitz, Josephine Cox, Dilbinder K. Gill, Jill Gilmour, Michael C. Keefer, Patricia Fast & David D. Ho. (2010) Phase 1 Safety and Immunogenicity Evaluation of ADVAX, a Multigenic, DNA-Based Clade C/B' HIV-1 Candidate Vaccine. PLoS ONE 5:1, pages e8617.
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Alvaro Lladser, Karl Ljungberg, Helena Tufvesson, Marcella Tazzari, Anna-Karin Roos, Andrew F. G. Quest & Rolf Kiessling. (2009) Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection against mouse melanoma. Cancer Immunology, Immunotherapy 59:1, pages 81-92.
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Jean-Michel Escoffre, Chloé Mauroy, Thomas Portet, Luc Wasungu, Aurelie Paganin-Gioanni, Muriel Golzio, Justin Teissié & Marie-Pierre Rols. (2009) Gene electrotransfer: from biophysical mechanisms to in vivo applications. Biophysical Reviews 1:4, pages 185-191.
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Simon R. Best, Shiwen Peng, Chi-Mou Juang, Chien-Fu Hung, Drew Hannaman, John R. Saunders, T.-C. Wu & Sara I. Pai. (2009) Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine 27:40, pages 5450-5459.
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