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Original Research

Adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart® in patients with relapsing multiple sclerosis: results of the 1-year, observational SMART study

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Read on this site (19)

Yu-Ting Lin, Tamara Will, Charlotte Wickham, Petra Boeree, Dominic Jack & Matthew Keiser. (2023) Evolution of the RebiSmart® Electromechanical Autoinjector to Improve Usability in Support of Adherence to Subcutaneous Interferon Beta-1a Therapy for People Living with Multiple Sclerosis. Patient Preference and Adherence 17, pages 1923-1933.
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Uwe Klaus Zettl, Paulus Stefan Rommer, Orhan Aktas, Torsten Wagner, Joachim Richter, Patrick Oschmann, Lukas Cepek, Birte Elias-Hamp, Klaus Gehring, Andrew Chan & Michael Hecker. (2023) Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation. Expert Review of Clinical Immunology 19:11, pages 1343-1359.
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Francesco Piras, Lilian Arnaud, Eric Henninger, Matthew Keiser, Andrea Seitzinger, Dominic Jack & Quentin Le Masne. (2023) Assessment of adherence to, and persistence with, an electromechanical autoinjector for subcutaneous interferon beta-1a injections for multiple sclerosis treatment over 3 years. Expert Opinion on Drug Delivery 20:6, pages 863-870.
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Zbyšek Pavelek, Michal Novotný, Blanka Klímová, Marek Peterka, Pavel Potužník, Martina Kövári & Martin Vališ. (2021) DORADA adherence study: full view into RebiSmart subdomains parameters in multiple sclerosis treatment. Current Medical Research and Opinion 37:4, pages 589-596.
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Daljit Tatla, Irina Mountian, Boglarka Szegvari, Brenda VanLunen & Michael Schiff. (2020) A multicenter, open-label study to evaluate the safe and effective use of a new electromechanical auto-injection device for self-injection of certolizumab pegol. Expert Opinion on Drug Delivery 17:6, pages 855-862.
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Martin Vališ, Jana Šarláková, Simona Halúsková, Blanka Klímová, Pavel Potužník, Marek Peterka, Kamil Kuča, Pavel Štourač, Jan Mareš & Zbyšek Pavelek. (2020) An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart®. Expert Opinion on Drug Delivery 17:5, pages 719-724.
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Beate Bittner, Chantal Schmit Chiesi, Saifuddin Kharawala, Gavneet Kaur & Johannes Schmidt. (2019) Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting. Medical Devices: Evidence and Research 12, pages 101-127.
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Scott Fettner, Christopher Mela, Florian Wildenhahn, Monica Tavanti, Christine Wells, Wendy Douglass & Navita L. Mallalieu. (2019) Evidence of bioequivalence and positive patient user handling of a tocilizumab autoinjector. Expert Opinion on Drug Delivery 16:5, pages 551-561.
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Elena Didenko Pedersen, Egon Stenager, JL Vadgaard, MB Jensen, R Schmid, N Meland, G Magnussen & Jette L Frederiksen. (2018) Adherence to subcutaneous interferon beta-1a treatment using an electronic injection device: a prospective open-label Scandinavian noninterventional study (the ScanSmart study). Patient Preference and Adherence 12, pages 569-575.
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Laura Dumitrescu, Cris S. Constantinescu & Radu Tanasescu. (2018) Recent developments in interferon-based therapies for multiple sclerosis. Expert Opinion on Biological Therapy 18:6, pages 665-680.
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Uwe Klaus Zettl, Michael Hecker, Orhan Aktas, Torsten Wagner & Paulus S. Rommer. (2018) Interferon β-1a and β-1b for patients with multiple sclerosis: updates to current knowledge. Expert Review of Clinical Immunology 14:2, pages 137-153.
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Andrea Zimmer, Michael Coslovsky, Ivo Abraham & Bernhard F Décard. (2017) Adherence to fingolimod in multiple sclerosis: an investigator-initiated, prospective, observational, single-center cohort study. Patient Preference and Adherence 11, pages 1815-1830.
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V Limmroth, J Reischl, B Mann, X Morosov, A Kokoschka, I Weller & T Schreiner. (2017) Autoinjector preference among patients with multiple sclerosis: results from a national survey. Patient Preference and Adherence 11, pages 1325-1334.
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María Dolores Edo Solsona, Emilio Monte Boquet, Bonaventura Casanova Estruch & José Luis Poveda Andrés. (2017) Impact of adherence on subcutaneous interferon beta-1a effectiveness administered by Rebismart® in patients with multiple sclerosis. Patient Preference and Adherence 11, pages 415-421.
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Marc C. Torjman, Robert Machnicki, Jennifer Lessin, Channy Loeum, Douglas Steinberger, Sarah Mycroft & Jeffrey I. Joseph. (2017) Evaluation of an investigational wearable injector in healthy human volunteers. Expert Opinion on Drug Delivery 14:1, pages 7-13.
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Peter Joseph Jongen, Wim A Lemmens, Raymond Hupperts, Erwin LJ Hoogervorst, Hans M Schrijver, Astrid Slettenaar, Els L de Schryver, Jan Boringa, Esther van Noort & Rogier Donders. (2016) Persistence and adherence in multiple sclerosis patients starting glatiramer acetate treatment: assessment of relationship with care received from multiple disciplines. Patient Preference and Adherence 10, pages 909-917.
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Damiano Paolicelli, Eleonora Cocco, Valentina Di Lecce, Vita Direnzo, Lucia Moiola, Roberta Lanzillo, Paola Perini, Simona Malucchi, Giovanna Borriello, Emilio Portaccio, Valentina Panetta, Giuseppe Fenu, Francesca Sangalli, Laura Cacciaguerra & Maria Trojano. (2016) Exploratory analysis of predictors of patient adherence to subcutaneous interferon beta-1a in multiple sclerosis: TRACER study. Expert Opinion on Drug Delivery 13:6, pages 799-805.
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Articles from other publishers (15)

Raed Al-Roughani, Magd Zakaria, Edward J. Cupler & Karim Taha. (2023) Adherence to subcutaneous interferon beta-1a treatment among patients with relapsing multiple sclerosis: the MAIN-MS study. Frontiers in Neurology 14.
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Hanne van Ballegooijen, Karin van der Hiele, Christian Enzinger, Gert de Voer & Leo H. Visser. (2022) The longitudinal relationship between fatigue, depression, anxiety, disability, and adherence with cognitive status in patients with early multiple sclerosis treated with interferon beta-1a. eNeurologicalSci 28, pages 100409.
Crossref
Peter Rieckmann, Tjalf Ziemssen, Iris-Katarina Penner, Alaleh Raji, Torsten Wagner, Joachim Richter & Uwe K. Zettl. (2022) Adherence to Subcutaneous Interferon Beta-1a in Multiple Sclerosis Patients Receiving Periodic Feedback on Drug Use by Discussion of Readouts of Their Rebismart® Injector: Results of the Prospective Cohort Study REBIFLECT. Advances in Therapy 39:6, pages 2749-2760.
Crossref
Joshua MardanMohammad Akhtar HussainMichelle AllanLisa B Grech. (2021) Objective medication adherence and persistence in people with multiple sclerosis: a systematic review, meta-analysis, and meta-regression. Journal of Managed Care & Specialty Pharmacy 27:9, pages 1273-1295.
Crossref
A. Blanco-López, C. Antillón-Ferreira, E. Saavedra-Castillo, M. Barrientos-Pérez, H. Rivero-Escalante, O. Flores-Caloca, R. Calzada-León, C. C. Rosas-Guerra, E. Koledova, E. Chiquete & A. Ayala-Estrada. (2020) Adherence to treatment in children with growth hormone deficiency, small for gestational age and Turner syndrome in Mexico: results of the Easypod™ connect observational study (ECOS). Journal of Endocrinological Investigation 43:10, pages 1447-1452.
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Sergio Sauri-Suárez, Sandra Quiñones-Aguilar, Arturo Contreras-Marín, Erik Omar Ramiro-Guerrero, David Zúñiga-García, Leticia Salinas-Vázquez, Leonardo Llamas-López, Carolina León-Jiménez, Adriana García-Martell, Iliana González-Hernández, Erwin Chiquete & Silvia García. (2020) Adherence to self-administering interferon-β1a using RebiSmart® device in Mexican patients with relapsing multiple sclerosis. PLOS ONE 15:4, pages e0230959.
Crossref
L.A. Visser, C. Louapre, C.A. Uyl-de Groot & W.K. Redekop. (2020) Patient needs and preferences in relapsing-remitting multiple sclerosis: A systematic review. Multiple Sclerosis and Related Disorders 39, pages 101929.
Crossref
Rafael Bolaños-Díaz, César Sanabria-Montañez & Nilton Custodio-Capuñay. (2019) Cost-effectiveness of interferon therapy for multiple sclerosis in Peru: impact of treatment adherence. Journal of Pharmaceutical Health Services Research 10:1, pages 125-132.
Crossref
Jovana Ivanović, Tatjana Pekmezović & Jelena Drulović. (2019) Interferon beta: Medication which started the revolution in the treatment of multiple sclerosis. Medicinski podmladak 70:1, pages 53-57.
Crossref
Peter Rieckmann, Matthias Schwab, Dieter Pöhlau, Iris-Katharina Penner, Torsten Wagner, Elke Schel & Antonios Bayas. (2018) Adherence to Subcutaneous IFN β-1a in Multiple Sclerosis: Final Analysis of the Non-Interventional Study READOUTsmart Using the Dosing Log and Readout Function of RebiSmart®. Advances in Therapy 36:1, pages 175-186.
Crossref
Spyros N. Deftereos, Evangelos Koutlas, Efrosini Koutsouraki, Athanassios Kyritsis, Panagiotis Papathanassopoulos, Nikolaos Fakas, Vaia Tsimourtou, Nikolaos Vlaikidis, Antonios Tavernarakis, Konstantinos Voumvourakis, Michalis Arvanitis, Dimitrios Sakellariou & Filippo DeLorenzo. (2018) Seasonal adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart® in patients with relapsing multiple sclerosis: results of the 1-year, observational GEPAT-SMART study. BMC Neurology 18:1.
Crossref
Martin Vališ & Zbyšek Pavelek. (2017) Multiple sclerosis - escalation therapies and evidence-based medicine. Neurologie pro praxi 18:Suppl.F, pages 13-17.
Crossref
Chiara Zecca, Giulio Disanto, Sarah Mühl & Claudio Gobbi. (2017) Subjective patient-reported versus objective adherence to subcutaneous interferon β-1a in multiple sclerosis using RebiSmart®: the CORE study. BMC Neurology 17:1.
Crossref
Donald A. Barone, Barry A. Singer, Lubo Merkov, Mark Rametta & Gustavo Suarez. (2016) Survey of US Patients with Multiple Sclerosis: Comparison of the New Electronic Interferon Beta-1b Autoinjector (BETACONNECT™) With Mechanical Autoinjectors. Neurology and Therapy 5:2, pages 155-167.
Crossref
Anthony L Traboulsee, Peter Cornelisseª, Magnhild Sandberg-Wollheim, Bernard MJ Uitdehaag, Ludwig Kappos, Peter J Jongen, Cris S Constantinescu, Elisabetta Verdun di Cantogno & David KB Li. (2016) Prognostic factors for long-term outcomes in relapsing–remitting multiple sclerosis. Multiple Sclerosis Journal - Experimental, Translational and Clinical 2, pages 205521731666640.
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