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Journal of Microencapsulation
Micro and Nano Carriers
Volume 28, 2011 - Issue 3
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Original

Novel dithranol phospholipid microemulsion for topical application: development, characterization and percutaneous absorption studies

Kaisar Raza Drug Delivery Research Group, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160014, India
,
Poonam Negi Drug Delivery Research Group, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160014, India
,
Shweta Takyar Drug Delivery Research Group, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160014, India
,
Anshuman Shukla Drug Delivery Research Group, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160014, India
,
Basant Amarji Drug Delivery Research Group, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160014, India
&
O. P. Katare Drug Delivery Research Group, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160014, IndiaCorrespondence[email protected]
Pages 190-199 | Received 25 Jun 2010, Accepted 03 Dec 2010, Published online: 18 May 2011

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Ruchi Gupta, Madhu Gupta, Sharad Mangal, Udita Agrawal & Suresh Prasad Vyas. (2016) Capsaicin-loaded vesicular systems designed for enhancing localized delivery for psoriasis therapy. Artificial Cells, Nanomedicine, and Biotechnology 44:3, pages 825-834.
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Poonam Negi, Bhupinder Singh, Gajanand Sharma, Sarwar Beg, Kaisar Raza & Om Prakash Katare. (2016) Phospholipid microemulsion-based hydrogel for enhanced topical delivery of lidocaine and prilocaine: QbD-based development and evaluation. Drug Delivery 23:3, pages 941-957.
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N. K. Yadav, Sanju Nanda, Gajanand Sharma & O. P. Katare. (2016) Systematically optimized coenzyme q10-loaded novel proniosomal formulation for treatment of photo-induced aging in mice: characterization, biocompatibility studies, biochemical estimations and anti-aging evaluation. Journal of Drug Targeting 24:3, pages 257-271.
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Poonam Negi, Bhupinder Singh, Gajanand Sharma, Sarwar Beg & Om Prakash Katare. (2015) Biocompatible lidocaine and prilocaine loaded-nanoemulsion system for enhanced percutaneous absorption: QbD-based optimisation, dermatokinetics and in vivo evaluation. Journal of Microencapsulation 32:5, pages 419-431.
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Faiyaz Shakeel, Nazrul Haq, Abdullah Al-Dhfyan, Fars K. Alanazi & Ibrahim A. Alsarra. (2015) Chemoprevention of skin cancer using low HLB surfactant nanoemulsion of 5-fluorouracil: a preliminary study. Drug Delivery 22:4, pages 573-580.
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Anuj G. Agrawal, Ashok Kumar & Paraag S. Gide. (2015) Formulation of solid self-nanoemulsifying drug delivery systems using N-methyl pyrrolidone as cosolvent. Drug Development and Industrial Pharmacy 41:4, pages 594-604.
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Mahfoozur Rahman, Sohail Akhter, Javed Ahmad, Mohammad Zaki Ahmad, Sarwar Beg & Farhan Jalees Ahmad. (2015) Nanomedicine-based drug targeting for psoriasis: potentials and emerging trends in nanoscale pharmacotherapy. Expert Opinion on Drug Delivery 12:4, pages 635-652.
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Yaw-Bin Huang, Chi-Te Huang, Hsin-Yeh Tsou, Li-Tse Fu, Yaw-Sya Fu, Yi-Hung Tsai & Pao-Chu Wu. (2013) The transport effect of submicron emulsions on 5-flurouracil topical application. Journal of Microencapsulation 30:5, pages 425-431.
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Shilpa Kakkar & Indu Pal Kaur. (2013) A novel nanovesicular carrier system to deliver drug topically. Pharmaceutical Development and Technology 18:3, pages 673-685.
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Udita Agrawal, Neelesh Kumar Mehra, Umesh Gupta & N. K. Jain. (2013) Hyperbranched dendritic nano-carriers for topical delivery of dithranol. Journal of Drug Targeting 21:5, pages 497-506.
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Kaisar Raza, Om Prakash Katare, Arvind Setia, Amit Bhatia & Bhupinder Singh. (2013) Improved therapeutic performance of dithranol against psoriasis employing systematically optimized nanoemulsomes. Journal of Microencapsulation 30:3, pages 225-236.
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Gajanand Sharma, Akanksha Mahajan, Kanika Thakur, Gurjeet Kaur, Vijay G. Goni, Muniramiah Vinod Kumar, Ravi Pratap Barnwal, Gurpal Singh, Bhupinder Singh & O. P. Katare. (2023) Exploring the therapeutic potential of sodium deoxycholate tailored deformable-emulsomes of etodolac for effective management of arthritis. Scientific Reports 13:1.
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Varsha Kadian & Rekha Rao. (2023) Exploring the in vitro anti-arthritic potential of capsaicin-coordinated β-cyclodextrin nanosponges. Journal of Drug Delivery Science and Technology 87, pages 104801.
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Sitah Alharthi, Zyta Maria Ziora, Gulam Mustafa, Pramila Chaubey, Ahmed Farag El Kirdasy & Ghallab Alotaibi. (2023) β-Caryophyllene-Loaded Microemulsion-Based Topical Hydrogel: A Promising Carrier to Enhance the Analgesic and Anti-Inflammatory Outcomes. Gels 9:8, pages 634.
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Prashant Upadhyay, Pooja Malik & Sukirti Upadhyay. (2023) Tea tree (Melaleuca alternifolia) Essential Oil Concentration in Microemulsion with Antibacterial and Antifungal Activity: An Overview. Current Drug Therapy 18:4, pages 298-311.
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Abdul Qadir, Dipak Kumar Gupta, Shehla Nasar Mir Najib Ullah, Mohd. AqilSamreen JahanNausheen Khan. (2023) Pinpoint and Stewardship of Psoriasis by Using Phytoconstituent-based Novel Formulation. Current Bioactive Compounds 19:4.
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Faisal K. Alkholifi, Aftab Alam, Ahmed I. Foudah & Hasan S. Yusufoglu. (2023) Phospholipid-Based Topical Nano-Hydrogel of Mangiferin: Enhanced Topical Delivery and Improved Dermatokinetics. Gels 9:3, pages 178.
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Varsha Kadian, Pooja Dalal, Sunil Kumar, Archana Kapoor & Rekha Rao. (2023) Comparative evaluation of dithranol-loaded nanosponges fabricated by solvent evaporation technique and melt method. Future Journal of Pharmaceutical Sciences 9:1.
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PriyaP Kadu. (2023) Topical non-steroidal immunomodulators in dermatology. Indian Dermatology Online Journal 14:3, pages 402.
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Paula Ângela de Souza Marinho Leite, Nadia Campos de Oliveira Miguel & Maria Bernadete Riemma Pierre. (2023) Microemulsions Improve Topical Protoporphyrin IX (PpIX) Delivery for Photodynamic Therapy of Skin Cancer. Brazilian Journal of Pharmaceutical Sciences 59.
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Nishtha Chaurawal, Charu Misra, Harshita Abul Barkat, Reena Jatyan, Deepak Chitkara, Md. Abul Barkat, Teenu Sharma, Bhupinder Singh & Kaisar Raza. (2022) Oral sorafenib-loaded microemulsion for breast cancer: evidences from the in-vitro evaluations and pharmacokinetic studies. Scientific Reports 12:1.
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Harish Sharma, Gyanesh Kumar Sahu & Chanchal Deep Kaur. (2021) Development of bioflavonoid containing chemotherapeutic delivery systems for UV-damaged skin and kangri cancer. Forum of Clinical Oncology 12:3, pages 86-98.
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Sunil Kumar & Rekha Rao. (2021) Novel Dithranol Loaded Cyclodextrin Nanosponges for Augmentation of Solubility, Photostability and Cytocompatibility. Current Nanoscience 17:5, pages 747-761.
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Jeet Gandhi, Disha Suthar, Hetal Patel, Pragna Shelat & Punit Parejiya. (2020) Development and characterization of microemulsion based topical gel of essential oil of clove (Syzygium aromaticum) for superficial fungal infections. Advances in Traditional Medicine 21:3, pages 519-534.
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Prativa Biswasroy, Deepak Pradhan, Biswakanth Kar, Goutam Ghosh & Goutam Rath. (2021) Recent Advancement in Topical Nanocarriers for the Treatment of Psoriasis. AAPS PharmSciTech 22:5.
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Varsha Kadian, Sunil Kumar, Komal Saini, Vandita Kakkar & Rekha Rao. (2021) Dithranol: An Insight into its Novel Delivery Cargos for Psoriasis Management. Current Drug Research Reviews 12:2, pages 82-96.
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Aung Than, Ping Zan & Peng Chen. (2020) Transdermal theranostics. View 1:2.
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Dina Fathalla, Eman M. K. Youssef & Ghareb M. Soliman. (2020) Liposomal and Ethosomal Gels for the Topical Delivery of Anthralin: Preparation, Comparative Evaluation and Clinical Assessment in Psoriatic Patients. Pharmaceutics 12:5, pages 446.
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Charul Rathore, Navneet Kumar Upadhyay, Aditi Sharma, Uma Ranjan Lal, Kaisar Raza & Poonam Negi. (2019) Phospholipid nanoformulation of thymoquinone with enhanced bioavailability: Development, characterization and anti-inflammatory activity. Journal of Drug Delivery Science and Technology 52, pages 316-324.
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Dalia S. Shaker, Rania A. H. Ishak, Amira Ghoneim & Muaeid A. Elhuoni. (2019) Nanoemulsion: A Review on Mechanisms for the Transdermal Delivery of Hydrophobic and Hydrophilic Drugs. Scientia Pharmaceutica 87:3, pages 17.
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Mohini Mishra, Pramod Kumar, Jitendra Singh Rajawat, Ruchi Malik, Gitanjali Sharma & Amit Modgil. (2019) Nanotechnology: Revolutionizing the Science of Drug Delivery. Current Pharmaceutical Design 24:43, pages 5086-5107.
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Pramod Kumar, Gajanand Sharma, Varun Gupta, Ramanpreet Kaur, Kanika Thakur, Ruchi Malik, Anil Kumar, Naveen Kaushal, Om Prakash Katare & Kaisar Raza. (2019) Oral Delivery of Methylthioadenosine to the Brain Employing Solid Lipid Nanoparticles: Pharmacokinetic, Behavioral, and Histopathological Evidences. AAPS PharmSciTech 20:2.
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Ana R. Fernandes, Carlos Martins-Gomes, Antonello Santini, Amélia M. Silva & Eliana B. Souto. 2018. Design of Nanostructures for Versatile Therapeutic Applications. Design of Nanostructures for Versatile Therapeutic Applications 379 406 .
Kaisar Raza, Shanti Ratan, Manish Kumar, Pramod Kumar, Saurabh Chaturvedi & Om Prakash Katare. (2017) Aceclofenac polymorphs: Preparation, characterization and intestinal permeation studies. Journal of Drug Delivery Science and Technology 39, pages 69-74.
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Gajanand Sharma, Geeta Dhankar, Kanika Thakur, Kaisar Raza & O. P. Katare. (2015) Benzyl Benzoate-Loaded Microemulsion for Topical Applications: Enhanced Dermatokinetic Profile and Better Delivery Promises. AAPS PharmSciTech 17:5, pages 1221-1231.
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M. Sala, A. Elaissari & H. Fessi. (2016) Advances in psoriasis physiopathology and treatments: Up to date of mechanistic insights and perspectives of novel therapies based on innovative skin drug delivery systems (ISDDS). Journal of Controlled Release 239, pages 182-202.
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Marina Jovanović & Zoran Golušin. (2016) Nonsteroidal Topical Immunomodulators in Allergology and Dermatology. BioMed Research International 2016, pages 1-11.
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Norazlinaliza Salim, Noraini Ahmad, Siti Hajar Musa, Rauzah Hashim, Tharwat F. Tadros & Mahiran Basri. (2016) Nanoemulsion as a topical delivery system of antipsoriatic drugs. RSC Advances 6:8, pages 6234-6250.
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Anuj G. Agrawal, Ashok Kumar & Paraag S. Gide. (2015) Self emulsifying drug delivery system for enhanced solubility and dissolution of glipizide. Colloids and Surfaces B: Biointerfaces 126, pages 553-560.
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Ana L. Savian, Daiane Rodrigues, Julia Weber, Roseane F. Ribeiro, Mariana H. Motta, Scheila R. Schaffazick, Andréa I.H. Adams, Diego F. de Andrade, Ruy C.R. Beck & Cristiane B. da Silva. (2015) Dithranol-loaded lipid-core nanocapsules improve the photostability and reduce the in vitro irritation potential of this drug. Materials Science and Engineering: C 46, pages 69-76.
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Marilene Estanqueiro, Jaime Conceição, Maria Helena Amaral & José Manuel Sousa Lobo. (2014) Use of solid dispersions to increase stability of dithranol in topical formulations. Brazilian Journal of Pharmaceutical Sciences 50:3, pages 583-590.
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Ming-Jun Tsai, Yaw-Syan Fu, Yu-Hsuan Lin, Yaw-Bin Huang & Pao-Chu Wu. (2014) The Effect of Nanoemulsion as a Carrier of Hydrophilic Compound for Transdermal Delivery. PLoS ONE 9:7, pages e102850.
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Kaisar Raza, Manish Kumar, Pramod Kumar, Ruchi Malik, Gajanand Sharma, Manmeet Kaur & O. P. Katare. (2014) Topical Delivery of Aceclofenac: Challenges and Promises of Novel Drug Delivery Systems. BioMed Research International 2014, pages 1-11.
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Bhavesh S. Barot, Punit B. Parejiya, Hetal K. Patel, Dharmik M. Mehta & Pragna K. Shelat. (2012) Microemulsion-based antifungal gel delivery to nail for the treatment of onychomycosis: formulation, optimization, and efficacy studies. Drug Delivery and Translational Research 2:6, pages 463-476.
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Monzer Fanun. (2012) Microemulsions as delivery systems. Current Opinion in Colloid & Interface Science 17:5, pages 306-313.
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Bhavesh S. Barot, Punit B. Parejiya, Hetal K. Patel, Mukesh C. Gohel & Pragna K. Shelat. (2011) Microemulsion-Based Gel of Terbinafine for the Treatment of Onychomycosis: Optimization of Formulation Using D-Optimal Design. AAPS PharmSciTech 13:1, pages 184-192.
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Yun Chao, Chi-Te Huang, Li-Tse Fu, Yaw-Bin Huang, Yi-Hung Tsai & Pao-Chu Wu. (2012) The Effect of Submicron Emulsion Systems on Transdermal Delivery of Kaempferol. Chemical and Pharmaceutical Bulletin 60:9, pages 1171-1175.
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