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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 27, 2010 - Issue 8
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Research Article

PERSPECTIVES ON THE CHRONOTHERAPY OF HYPERTENSION BASED ON THE RESULTS OF THE MAPEC STUDY

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Pages 1652-1667 | Received 10 Jul 2010, Accepted 20 Jul 2010, Published online: 20 Sep 2010

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José R. Fernández, Artemio Mojón & Ramón C. Hermida. (2020) Chronotherapy of hypertension: advantages of 48-h ambulatory blood pressure monitoring assessments in MAPEC and Hygia Chronotherapy Trial. Chronobiology International 37:5, pages 739-750.
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Peter Potucek, Michal Radik, Gabriel Doka, Eva Kralova, Peter Krenek & Jan Klimas. (2017) mRNA levels of circadian clock components Bmal1 and Per2 alter independently from dosing time-dependent efficacy of combination treatment with valsartan and amlodipine in spontaneously hypertensive rats. Clinical and Experimental Hypertension 39:8, pages 754-763.
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Xuepei Li, Junwen Guan, Wang Hou, Shuting Cheng, Zhou Jiang, Yuhui Wang, Yangyou Liu & Zhengrong Wang. (2016) The circadian intracranial pressure would be a prognostic factor in traumatic brain injury?. Biological Rhythm Research 47:6, pages 823-832.
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Michael H. Smolensky, Ramon C. Hermida, Alain Reinberg, Linda Sackett-Lundeen & Francesco Portaluppi. (2016) Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention. Chronobiology International 33:8, pages 1101-1119.
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T.C. Erren, P. Morfeld, R.G. Foster, R.J. Reiter, J.V. Groß & I.K. Westermann. (2016) Sleep and cancer: Synthesis of experimental data and meta-analyses of cancer incidence among some 1,500,000 study individuals in 13 countries. Chronobiology International 33:4, pages 325-350.
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Michael H. Smolensky, Linda L. Sackett-Lundeen & Francesco Portaluppi. (2015) Nocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases. Chronobiology International 32:8, pages 1029-1048.
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Chakrapani Mahabala, Padmanabha Kamath, Unnikrishnan Bhaskaran, Narasimha D Pai & Aparna U Pai. (2013) Antihypertensive therapy: nocturnal dippers and nondippers. Do we treat them differently?. Vascular Health and Risk Management 9, pages 125-133.
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Hiromi Rakugi, Kazuomi Kario, Kazuaki Enya, Masataka Igeta & Yoshinori Ikeda. (2013) Effect of azilsartan versus candesartan on nocturnal blood pressure variation in Japanese patients with essential hypertension. Blood Pressure 22:sup1, pages 22-28.
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Ramón C. Hermida, Michael H. Smolensky, Diana E. Ayala, Francesco Portaluppi, Juan J. Crespo, Fabio Fabbian, Erhard Haus, Roberto Manfredini, Artemio Mojón, Ana Moyá, Luis Piñeiro, María T. Ríos, Alfonso Otero, Horia Balan & José R. Fernández. (2013) 2013 Ambulatory Blood Pressure Monitoring Recommendations for the Diagnosis of Adult Hypertension, Assessment of Cardiovascular and other Hypertension-associated Risk, and Attainment of Therapeutic Goals. Chronobiology International 30:3, pages 355-410.
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Diana E. Ayala, Rafael Ucieda & Ramón C. Hermida. (2013) Chronotherapy With Low-Dose Aspirin for Prevention of Complications in Pregnancy. Chronobiology International 30:1-2, pages 260-279.
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Fabio Fabbian, Michael H. Smolensky, Ruana Tiseo, Marco Pala, Roberto Manfredini & Francesco Portaluppi. (2013) Dipper and Non-Dipper Blood Pressure 24-Hour Patterns: Circadian Rhythm–Dependent Physiologic and Pathophysiologic Mechanisms. Chronobiology International 30:1-2, pages 17-30.
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Roberto Manfredini, Benedetta Boari, Raffaella Salmi, Fabio Fabbian, Marco Pala, Ruana Tiseo & Francesco Portaluppi. (2013) Twenty-Four-Hour Patterns in Occurrence and Pathophysiology of Acute Cardiovascular Events and Ischemic Heart Disease. Chronobiology International 30:1-2, pages 6-16.
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Francesco Portaluppi, Erhard Haus & Michael H. Smolensky. (2013) Ambulatory Blood Pressure Monitoring: Killing the Elephant to Get Its Hair? No More, Please!. Chronobiology International 30:1-2, pages 1-5.
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Diana E. Ayala & Ramón C. Hermida. (2013) Ambulatory Blood Pressure Monitoring for the Early Identification of Hypertension in Pregnancy. Chronobiology International 30:1-2, pages 233-259.
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Ramón C. Hermida, Diana E. Ayala, José R. Fernández, Artemio Mojón, Michael H. Smolensky, Fabio Fabbian & Francesco Portaluppi. (2013) Administration-Time Differences in Effects of Hypertension Medications on Ambulatory Blood Pressure Regulation. Chronobiology International 30:1-2, pages 280-314.
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Artemio Mojón, Diana E. Ayala, Luis Piñeiro, Alfonso Otero, Juan J. Crespo, Ana Moyá, Julia Bóveda, Jesús Pérez de Lis, José R. Fernández & Ramón C. Hermida. (2013) Comparison of Ambulatory Blood Pressure Parameters of Hypertensive Patients With and Without Chronic Kidney Disease. Chronobiology International 30:1-2, pages 145-158.
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Ana Moyá, Juan J. Crespo, Diana E. Ayala, María T. Ríos, Lorenzo Pousa, Pedro A. Callejas, José L. Salgado, Artemio Mojón, José R. Fernández & Ramón C. Hermida. (2013) Effects of Time-of-Day of Hypertension Treatment on Ambulatory Blood Pressure and Clinical Characteristics of Patients With Type 2 Diabetes. Chronobiology International 30:1-2, pages 116-131.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Ambulatory Blood Pressure Thresholds for Diagnosis of Hypertension in Patients With and Without Type 2 Diabetes Based on Cardiovascular Outcomes. Chronobiology International 30:1-2, pages 132-144.
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Ramón C. Hermida, Diana E. Ayala, José R. Fernández & Artemio Mojón. (2013) Sleep-Time Blood Pressure: Prognostic Value and Relevance as a Therapeutic Target for Cardiovascular Risk Reduction. Chronobiology International 30:1-2, pages 68-86.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Role of Time-of-Day of Hypertension Treatment on the J-Shaped Relationship Between Blood Pressure and Cardiovascular Risk. Chronobiology International 30:1-2, pages 328-339.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Cardiovascular Risk of Essential Hypertension: Influence of Class, Number, and Treatment-Time Regimen of Hypertension Medications. Chronobiology International 30:1-2, pages 315-327.
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Diana E. Ayala, Ana Moyá, Juan J. Crespo, Carmen Castiñeira, Manuel Domínguez-Sardiña, Sonia Gomara, Elvira Sineiro, Artemio Mojón, María J. Fontao & Ramón C. Hermida. (2013) Circadian Pattern of Ambulatory Blood Pressure in Hypertensive Patients With and Without Type 2 Diabetes. Chronobiology International 30:1-2, pages 99-115.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón, María J. Fontao, Luisa Chayán & José R. Fernández. (2013) Differences Between Men and Women in Ambulatory Blood Pressure Thresholds for Diagnosis of Hypertension Based on Cardiovascular Outcomes. Chronobiology International 30:1-2, pages 221-232.
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Ramón C. Hermida, María T. Ríos, Juan J. Crespo, Ana Moyá, Manuel Domínguez-Sardiña, Alfonso Otero, Juan J. Sánchez, Artemio Mojón, José R. Fernández & Diana E. Ayala. (2013) Treatment-Time Regimen of Hypertension Medications Significantly Affects Ambulatory Blood Pressure and Clinical Characteristics of Patients With Resistant Hypertension. Chronobiology International 30:1-2, pages 192-206.
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Juan J. Crespo, Luis Piñeiro, Alfonso Otero, Carmen Castiñeira, María T. Ríos, Antonio Regueiro, Artemio Mojón, Sonia Lorenzo, Diana E. Ayala & Ramón C. Hermida. (2013) Administration-Time-Dependent Effects of Hypertension Treatment on Ambulatory Blood Pressure in Patients With Chronic Kidney Disease. Chronobiology International 30:1-2, pages 159-175.
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Ramón C. Hermida, Diana E. Ayala, María J. Fontao, Artemio Mojón,José R. Fernández. (2013) Ambulatory Blood Pressure Monitoring: Importance of Sampling Rate and Duration—48 Versus 24 Hours—on the Accurate Assessment of Cardiovascular Risk. Chronobiology International 30:1-2, pages 55-67.
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Diana E. Ayala, Ramón C. Hermida, Artemio Mojón & José R. Fernández. (2013) Cardiovascular Risk of Resistant Hypertension: Dependence on Treatment-Time Regimen of Blood Pressure–Lowering Medications. Chronobiology International 30:1-2, pages 340-352.
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Daniela Grimaldi, Federica Provini, Giovanna Calandra-Buonaura, Giorgio Barletta, Annagrazia Cecere, Giulia Pierangeli & Pietro Cortelli. (2013) Cardiovascular-Sleep Interaction in Drug-Naïve Patients With Essential Grade I Hypertension. Chronobiology International 30:1-2, pages 31-42.
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María T. Ríos, Manuel Domínguez-Sardiña, Diana E. Ayala, Sonia Gomara, Elvira Sineiro, Lorenzo Pousa, Pedro A. Callejas, María J. Fontao, José R. Fernández & Ramón C. Hermida. (2013) Prevalence and Clinical Characteristics of Isolated-Office and True Resistant Hypertension Determined by Ambulatory Blood Pressure Monitoring. Chronobiology International 30:1-2, pages 207-220.
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Ramón C. Hermida, Diana E. Ayala, Juan J. Crespo, Artemio Mojón, Luisa Chayán, María J. Fontao & José R. Fernández. (2013) Influence of Age and Hypertension Treatment-time on Ambulatory Blood Pressure in Hypertensive Patients. Chronobiology International 30:1-2, pages 176-191.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Blunted Sleep-Time Relative Blood Pressure Decline Increases Cardiovascular Risk Independent of Blood Pressure Level—The “Normotensive Non-dipper” Paradox. Chronobiology International 30:1-2, pages 87-98.
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Elena V. Tsimakouridze, Marty Straume, Peter S. Podobed, Heather Chin, Jonathan LaMarre, Ron Johnson, Monica Antenos, Gordon M. Kirby, Allison Mackay, Patsy Huether, Jeremy A. Simpson, Michael Sole, Gerard Gadal & Tami A. Martino. (2012) Chronomics of Pressure Overload–Induced Cardiac Hypertrophy in Mice Reveals Altered Day/Night Gene Expression and Biomarkers of Heart Disease. Chronobiology International 29:7, pages 810-821.
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Yuval Weigl, Leah Peleg, Aviva Dotan,Israel E. Ashkenazi. (2012) Cisplatin Effects on Rhythmic Functions of Mice: Strain and Tissue Dependence. Chronobiology International 29:6, pages 724-735.
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A. Blazquez, A. Martinez-Nicolas, F. J. Salazar, M. A. Rol,J. A. Madrid. (2012) Wrist Skin Temperature, Motor Activity, and Body Position as Determinants of the Circadian Pattern of Blood Pressure. Chronobiology International 29:6, pages 747-756.
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Helen Jones, Nia C.S. Lewis, Andrew Thompson, Kelly Marrin, Daniel J. Green & Greg Atkinson. (2012) Diurnal Variation in Vascular Function: Role of Sleep. Chronobiology International 29:3, pages 271-277.
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Stefano Bastianini, Alessandro Silvani, Chiara Berteotti, Viviana Lo Martire & Giovanna Zoccoli. (2012) Mice Show Circadian Rhythms of Blood Pressure During Each Wake-Sleep State. Chronobiology International 29:1, pages 82-86.
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Masato Sasaki, Hitoshi Ando & Akio Fujimura. (2012) Lack of Nocturnal Blood Pressure Fall in Elderly Bedridden Hypertensive Patients With Cerebrovascular Disease. Chronobiology International 29:1, pages 62-65.
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Ramón C. Hermida, Luisa Chayán, Diana E. Ayala, Artemio Mojón, María J. Fontao & José R. Fernández. (2011) Relationship Between Metabolic Syndrome, Circadian Treatment Time, and Blood Pressure Non-Dipping Profile in Essential Hypertension. Chronobiology International 28:6, pages 509-519.
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