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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 30, 2015 - Issue 1
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Research Article

Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties

Ahmed M. AlafeefyDepartment of Pharmaceutical Chemistry, College of Pharmacy, Salman bin Abdulaziz University, Alkharj, Saudi Arabia,
,
Hatem A. Abdel-AzizDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia, ;Department of Applied Organic Chemistry, National Research Center, Dokki, Cairo, Egypt,
,
Daniela VulloLaboratorio di Chimica Bioinorganica, Polo Scientifico, Università degli Studi di Firenze, Sesto Fiorentino, Florence, Italy,
,
Abdul-Malek S. Al-TamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Salman bin Abdulaziz University, Alkharj, Saudi Arabia,
,
Amani S. AwaadChemistry Department, Faculty of Science, King Saud University, Riyadh, Saudi Arabia,
,
Menshawy A. MohamedDepartment of Pharmaceutical Chemistry, College of Pharmacy, Salman bin Abdulaziz University, Alkharj, Saudi Arabia, ;Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt,
,
Clemente CapassoIstituto di Biochimica delle Proteine and IBBR – CNR, Napoli, Italy, and
&
Claudiu T. SupuranLaboratorio di Chimica Bioinorganica, Polo Scientifico, Università degli Studi di Firenze, Sesto Fiorentino, Florence, Italy, ;Neurofarba Department, Section of Pharmaceutical and Nutriceutical Sciences, Università degli Studi di Firenze, Sesto Fiorentino, Florence, ItalyCorrespondence[email protected]
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Pages 52-56 | Received 03 Dec 2013, Accepted 18 Dec 2013, Published online: 25 Mar 2014

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Tarfah Al-Warhi, Mostafa M. Elbadawi, Alessandro Bonardi, Alessio Nocentini, Ahmed A. Al-Karmalawy, Nada Aljaeed, Ohoud J. Alotaibi, Hatem A. Abdel-Aziz, Claudiu T. Supuran & Wagdy M. Eldehna. (2022) Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2635-2643.
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Haytham O. Tawfik, Moataz A. Shaldam, Alessio Nocentini, Rofaida Salem, Hadia Almahli, Sara T. Al-Rashood, Claudiu T. Supuran & Wagdy M. Eldehna. (2022) Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 1043-1052.
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Samir Bondock, Tallah Albarqi & Mohamed Abboud. (2021) Advances in the synthesis and chemical transformations of 5-acetyl-1,3,4-thiadiazolines. Journal of Sulfur Chemistry 42:2, pages 202-240.
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Claudiu T. Supuran & Clemente Capasso. (2020) Antibacterial carbonic anhydrase inhibitors: an update on the recent literature. Expert Opinion on Therapeutic Patents 30:12, pages 963-982.
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Claudiu T. Supuran & Clemente Capasso. (2018) Biomedical applications of prokaryotic carbonic anhydrases. Expert Opinion on Therapeutic Patents 28:10, pages 745-754.
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Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Fatmah A. S. Alasmary, Zeid AlOthman, William A. Donald, Clemente Capasso & Claudiu T. Supuran. (2018) Comparison of the amine/amino acid activation profiles of the β- and γ-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 25-30.
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Sonia Del Prete, Rosa Perfetto, Mosè Rossi, Fatmah A. S. Alasmary, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran & Clemente Capasso. (2017) A one-step procedure for immobilising the thermostable carbonic anhydrase (SspCA) on the surface membrane of Escherichia coli. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1120-1128.
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Rosa Perfetto, Sonia Del Prete, Daniela Vullo, Vincenzo Carginale, Giovanni Sansone, Carmela M. A. Barone, Mosè Rossi, Fatmah A. S. Alasmary, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran & Clemente Capasso. (2017) Cloning, expression and purification of the α-carbonic anhydrase from the mantle of the Mediterranean mussel, Mytilus galloprovincialis. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1029-1035.
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Claudiu T. Supuran. (2016) How many carbonic anhydrase inhibition mechanisms exist?. Journal of Enzyme Inhibition and Medicinal Chemistry 31:3, pages 345-360.
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Sonia Del Prete, Daniela Vullo, Viviana De Luca, Zeid AlOthman, Sameh M. Osman, Claudiu T. Supuran & Clemente Capasso. (2015) Biochemical characterization of recombinant β-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis. Journal of Enzyme Inhibition and Medicinal Chemistry 30:3, pages 366-370.
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Claudiu Supuran & Clemente Capasso. (2017) An Overview of the Bacterial Carbonic Anhydrases. Metabolites 7:4, pages 56.
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Sonia Del Prete, Daniela Vullo, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran & Clemente Capasso. (2017) Sulfonamide inhibition profiles of the β-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia. Bioorganic & Medicinal Chemistry 25:13, pages 3555-3561.
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