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Clinical Toxicology Volume 54, 2016 - Issue 3
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Review

Systematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity

Lotte C. G. HoegbergDepartment of Anesthesiology, Danish Poisons Information Centre, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark; Correspondence[email protected]
,
Theodore C. BaniaDepartment of Emergency Medicine, Mt Sinai Roosevelt, Mt Sinai St. Luke's, Icahn School of Medicine, New York, NY, USA;
,
Valéry LavergneDepartment of Medical Biology, Sacré-Coeur Hospital, University Of Montréal, Montréal, Canada;
,
Benoit BaileyDivision of Emergency Medicine, Department of Pediatrics, CHU Sainte-Justine, Montreal, Canada; ;Centre Antipoison du Québec, Québec, Canada;
,
Alexis F. TurgeonDivision of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, CHU de Québec – Université Laval Research Center, Population Health and Optimal Health Practices Unit, Université Laval, Québec City, Canada;
,
Simon H. L. ThomasNational Poisons Information Service (Newcastle) and Medical Toxicology Centre, Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom;
,
Martin MorrisSchulich Library of Science and Engineering, McGill University, Montréal, Canada;
,
Andrea Miller-NesbittSchulich Library of Science and Engineering, McGill University, Montréal, Canada;
,
Bruno MégarbaneDepartment of Medical and Toxicological Intensive Care, Lariboisière Hospital, Paris-Diderot University, Paris, France;
,
Sheldon MagderDepartment of Critical Care, McGill University Health Centre, Montreal, Canada;
,
Sophie GosselinCentre Antipoison du Québec, Québec, Canada; ;Department of Emergency Medicine, McGill University Health Centre, Montréal, Canada
& Lipid Emulsion Workgroup show all
Pages 167-193 | Received 03 Jun 2015, Accepted 11 Nov 2015, Published online: 06 Feb 2016

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Matilde Zaballos, Ignacio Fernández, Lucia Rodríguez, Sergio García, Olalla Varela, Oscar Quintela, María-José Anadón & Jesús Almendral. (2022) Effects of intravenous lipid emulsions on the reversal of pacing-induced ventricular arrhythmias and electrophysiological alterations in an animal model of ropivacaine toxicity. Clinical Toxicology 60:8, pages 902-911.
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Robert S. Hoffman, Sophie Gosselin, Eric Villeneuve, Bryan D. Hayes, Lotte C. G. Hoegberg & Susan C. Smolinske. (2020) Comment on Antidotal use of lipid emulsion – the pendulum swings. Clinical Toxicology 58:12, pages 1355-1356.
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Michael E. Mullins & Donna L. Seger. (2020) Antidotal use of lipid emulsion – the pendulum swings. Clinical Toxicology 58:12, pages 1281-1283.
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Susan Smolinske, Robert S. Hoffman, Eric Villeneuve, Lotte C. G. Hoegberg & Sophie Gosselin. (2019) Utilization of lipid emulsion therapy in fatal overdose cases: an observational study. Clinical Toxicology 57:3, pages 197-202.
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Rhadika Souza, Joshua Jauregui & Matthew Valento. (2018) Mixed propranolol and tizanidine overdose treated with intravenous lipid emulsion. Toxicology Communications 2:1, pages 71-74.
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Lotte C. G. Hoegberg, Robert S. Hoffman, Bryan D. Hayes, Valéry Lavergne & Sophie Gosselin. (2017) Letter in response to “Lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis”. Clinical Toxicology 55:9, pages 1019-1019.
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Michael R. Fettiplace & Daniel J. McCabe. (2017) Lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis. Clinical Toxicology 55:7, pages 617-623.
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Daniel J. Corwin, Alexis Topjian, Brenda L. Banwell & Kevin Osterhoudt. (2017) Adverse events associated with a large dose of intravenous lipid emulsion for suspected local anesthetic toxicity. Clinical Toxicology 55:6, pages 603-607.
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Michael E. Mullins. (2016) Advancing the science of antidotal use of lipid emulsion. Clinical Toxicology 54:10, pages 897-898.
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Sophie Gosselin, Lotte C. G. Hoegberg, Robert. S. Hoffman, Andis Graudins, Christine M. Stork, Simon H. L. Thomas, Samuel J. Stellpflug, Bryan D. Hayes, Michael Levine, Martin Morris, Andrea Nesbitt-Miller, Alexis F. Turgeon, Benoit Bailey, Diane P. Calello, Ryan Chuang, Theodore C. Bania, Bruno Mégarbane, Ashish Bhalla & Valéry Lavergne. (2016) Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning. Clinical Toxicology 54:10, pages 899-923.
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Floyd Besserer, Ryan Chuang, Matt Mink, Laurie Massey & Bruce Cload. (2016) Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. Clinical Toxicology 54:8, pages 812-813.
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