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Original Article

Validation of the Bowel Function Index to detect clinically meaningful changes in opioid-induced constipation

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Pages 371-383 | Published online: 16 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (34)

Michael A. Ueberall, Ute Essner, Gerhard Müller-Schwefe, Johannes Horlemann & Martin Storr. (2022) Prevalence of drug-induced constipation and severity of associated biopsychosocial effects in patients with nonmalignant pain: a cross-sectional review of depersonalized data from the German Pain e-Registry. Current Medical Research and Opinion 38:1, pages 101-114.
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Shankar Ganesh & Mritunjay Kumar. (2021) Physiotherapist management of a patient with spastic perineal syndrome and subsequent constipation: a case report. Physiotherapy Theory and Practice 37:1, pages 242-251.
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Joanne Patel, Catherine J. Lucas, Maxwell Margalit & Jennifer H. Martin. (2018) Laxative Use in Inpatients on Oxycodone/Naloxone Prolonged Release and Oxycodone Prolonged Release for Cancer and Non-cancer Pain. Journal of Pain & Palliative Care Pharmacotherapy 32:2-3, pages 116-123.
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Gineke Koopmans-Klein, Joeri Van Op den Bosch, Yvonne van Megen, Hans Prenen, Frank Huygen & Isabelle Mancini. (2017) Prolonged release oxycodone and naloxone treatment counteracts opioid-induced constipation in patients with severe pain compared to previous analgesic treatment. Current Medical Research and Opinion 33:12, pages 2217-2227.
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Krzysztof Nosek, Wojciech Leppert, Hanna Nosek, Jerzy Wordliczek & Dariusz Onichimowski. (2017) A comparison of oral controlled-release morphine and oxycodone with transdermal formulations of buprenorphine and fentanyl in the treatment of severe pain in cancer patients. Drug Design, Development and Therapy 11, pages 2409-2419.
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María Dueñas, Liliane Mendonça, Rute Sampaio, Cláudia Gouvinhas, Daniela Oliveira, José Manuel Castro-Lopes & Luís Filipe Azevedo. (2017) Reliability and validity of the Bowel Function Index for evaluating opioid-induced constipation: translation, cultural adaptation and validation of the Portuguese version (BFI-P). Current Medical Research and Opinion 33:3, pages 563-572.
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Stefano De Santis, Cristina Borghesi, Serena Ricciardi, Daniele Giovannoni, Alberto Fulvi, Maria Rita Migliorino & Claudio Marcassa. (2016) Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain: an observational analysis. OncoTargets and Therapy 9, pages 4043-4052.
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Emiliano Petrò, Elena Ruffini, Melania Cappuccio, Valeria Guerini, Gloria Belotti, Sara Fascendini, Cristina Licini & Claudio Marcassa. (2016) Low-dose oral prolonged-release oxycodone/naloxone for chronic pain in elderly patients with cognitive impairment: an efficacy–tolerability pilot study. Neuropsychiatric Disease and Treatment 12, pages 559-569.
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Michael A Ueberall, Alice Eberhardt & Gerhard HH Mueller-Schwefe. (2016) Quality of life under oxycodone/naloxone, oxycodone, or morphine treatment for chronic low back pain in routine clinical practice. International Journal of General Medicine 9, pages 39-51.
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Fabio Guerriero, Anna Roberto, Maria Teresa Greco, Carmelo Sgarlata, Marco Rollone & Oscar Corli. (2016) Long-term efficacy and safety of oxycodone–naloxone prolonged release in geriatric patients with moderate-to-severe chronic noncancer pain: a 52-week open-label extension phase study. Drug Design, Development and Therapy 10, pages 1515-1523.
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Matias Nilsson, Christina Brock, Jakob Lykke Poulsen, Niels Bindslev, Mark Berner Hansen, Lona Louring Christrup & AM Drewes. (2016) Short-term oxycodone treatment does not affect electrogenic ion transport in isolated mucosa from the human rectosigmoid colon. Scandinavian Journal of Gastroenterology 51:5, pages 538-547.
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Gineke Koopmans-Klein, Michel F.M. Wagemans, Hans C.H. Wartenberg, Yvonne J.B. Van Megen & Frank J.P.M. Huygen. (2016) The efficacy of standard laxative use for the prevention and treatment of opioid induced constipation during oxycodone use: a small Dutch observational pilot study. Expert Review of Gastroenterology & Hepatology 10:4, pages 547-553.
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Marzia Lazzari, Claudio Marcassa, Silvia Natoli, Roberta Carpenedo, Clarissa Caldarulo, Maria B Silvi & Mario Dauri. (2016) Switching to low-dose oral prolonged-release oxycodone/naloxone from WHO-Step I drugs in elderly patients with chronic pain at high risk of early opioid discontinuation. Clinical Interventions in Aging 11, pages 641-649.
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Marzia Lazzari, Maria Teresa Greco, Claudio Marcassa, Simona Finocchi, Clarissa Caldarulo & Oscar Corli. (2015) Efficacy and tolerability of oral oxycodone and oxycodone/naloxone combination in opioid-naïve cancer patients: a propensity analysis. Drug Design, Development and Therapy 9, pages 5863-5872.
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Guido Fanelli & Andrea Fanelli. (2015) Developments in managing severe chronic pain: role of oxycodone–naloxone extended release. Drug Design, Development and Therapy 9, pages 3811-3816.
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Wojciech Leppert. (2015) Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction. Drug Design, Development and Therapy 9, pages 2215-2231.
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Fabio Guerriero, Carmelo Sgarlata, Claudio Marcassa, Giovanni Ricevuti & Marco Rollone. (2015) Efficacy and tolerability of low-dose oral prolonged-release oxycodone/naloxone for chronic nononcological pain in older patients. Clinical Interventions in Aging 10, pages 1-11.
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Sabine Hesselbarth, Kai Hermanns & Petra Oepen. (2015) Prolonged-release oxycodone/naloxone in opioid-naïve patients – subgroup analysis of a prospective observational study. Expert Opinion on Pharmacotherapy 16:4, pages 457-464.
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Thomas Nolte, Ulf Schutter & Oliver Loewenstein. (2014) Cancer pain therapy with a fixed combination of prolonged-release oxycodone/naloxone: results from a non-interventional study. Pragmatic and Observational Research 5, pages 1-13.
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Gineke Koopmans, Karen Simpson, Javier De Andrés, Eberhard Albert Lux, Michel Wagemans & Yvonne Van Megen. (2014) Fixed ratio (2:1) prolonged-release oxycodone/naloxone combination improves bowel function in patients with moderate-to-severe pain and opioid-induced constipation refractory to at least two classes of laxatives. Current Medical Research and Opinion 30:11, pages 2389-2396.
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M. Lazzari, A. F. Sabato, C. Caldarulo, M. Casali, P. Gafforio, C. Marcassa & F. Leonardis. (2014) Effectiveness and tolerability of low-dose oral oxycodone/naloxone added to anticonvulsant therapy for noncancer neuropathic pain: an observational analysis. Current Medical Research and Opinion 30:4, pages 555-564.
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L. Abramowitz, N. Béziaud, C. Caussé, B. Chuberre, F. A. Allaert & S. Perrot. (2013) Further validation of the psychometric properties of the Bowel Function Index for evaluating opioid-induced constipation (OIC). Journal of Medical Economics 16:12, pages 1434-1441.
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L. Abramowitz, N. Béziaud, L. Labreze, V. Giardina, C. Caussé, B. Chuberre, F. A. Allaert & S. Perrot. (2013) Prevalence and impact of constipation and bowel dysfunction induced by strong opioids: a cross-sectional survey of 520 patients with cancer pain: DYONISOS study. Journal of Medical Economics 16:12, pages 1423-1433.
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Philippe Ducrotté & Christian Caussé. (2012) The Bowel Function Index: a new validated scale for assessing opioid-induced constipation. Current Medical Research and Opinion 28:3, pages 457-466.
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Kai Hermanns, Uwe Junker & Thomas Nolte. (2012) Prolonged-release oxycodone/naloxone in the treatment of neuropathic pain – results from a large observational study. Expert Opinion on Pharmacotherapy 13:3, pages 299-311.
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Benoît Coffin & Christian Caussé. (2011) Constipation assessment scales in adults: a literature review including the new Bowel Function Index. Expert Review of Gastroenterology & Hepatology 5:5, pages 601-613.
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A.M. Rentz, P. van Hanswijck de Jonge, P. Leyendecker & M. Hopp. (2011) Observational, nonintervention, multicenter study for validation of the bowel function index for constipation in european countries. Current Medical Research and Opinion 27:1, pages 35-44.
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