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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 10
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Clinical Pharmacokinetics and Metabolism

Human mass balance, metabolite profile and identification of metabolic enzymes of [14C]ASP015K, a novel oral janus kinase inhibitor

Kazuo OdaAnalysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc., Osaka, Japan, Correspondence[email protected]
,
Ying J. CaoDrug Discovery Science & Management-US, Astellas Research Institute of America LLC, Northbrook, IL, USA,
,
Taiji SawamotoClinical Pharmacology, Astellas Pharma Inc., Tokyo, Japan, and
,
Naoyuki NakadaAnalysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc., Osaka, Japan,
,
Ogert FisnikuBioanalysis-US, Astellas Research Institute of America LLC, Skokie, IL, USA
,
Yasuhisa NagasakaAnalysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc., Osaka, Japan,
&
Kin-ya SohdaAnalysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc., Osaka, Japan,
show all
Pages 887-902 | Received 20 Jan 2015, Accepted 04 Mar 2015, Published online: 19 May 2015

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