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Volume 11, Issue 10

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 10 (2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 10 (2015)

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Editorial

PCSK9 inhibitors – past, present and future

Željko Reiner

Pages: 1517-1521

Published online: 03 Aug 2015

AbstractforPCSK9 inhibitors – past, present and future | Full Text | References | PDF (165 KB)

3372 Views
34 CrossRef citations
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Free Access

Review

Development of novel tools for the in vitro investigation of drug-induced liver injury

Jian Jiang (Faculty of Health, Medicine and Life Sciences) , Jarno EJ Wolters, Simone G van Breda, Jos C Kleinjans & Theo M de Kok

Pages: 1523-1537

Published online: 09 Jul 2015

AbstractforDevelopment of novel tools for the in vitro investigation of drug-induced liver injury | Full Text | References | PDF (335.1 KB)

1368 Views
40 CrossRef citations
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Theoretical pharmacokinetic drug alterations in pediatric celiac disease

Tran H Tran (Assistant Clinical Professor) PharmD BCPS, Candace Smith (Associate Clinical Professor) PharmD & Robert A Mangione (Provost and Professor of Pharmacy) EdD RPh

Pages: 1539-1550

Published online: 09 Jul 2015

AbstractforTheoretical pharmacokinetic drug alterations in pediatric celiac disease | Full Text | References | PDF (365.6 KB)

170 Views
1 CrossRef citations
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Herbal hepatotoxicity: current status, examples, and challenges

Carlemi Calitz, Lissinda du Plessis, Chrisna Gouws, Dewald Steyn, Jan Steenekamp, Christo Muller & Sias Hamman

Pages: 1551-1565

Published online: 06 Jul 2015

AbstractforHerbal hepatotoxicity: current status, examples, and challenges | Full Text | References | PDF (363.6 KB)

553 Views
37 CrossRef citations
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Mathematical models for dermal drug absorption

Dominik Selzer, Dirk Neumann & Ulrich F Schaefer (Professor)

Pages: 1567-1583

Published online: 13 Jul 2015

AbstractforMathematical models for dermal drug absorption | Full Text | References | PDF (633.8 KB)

391 Views
13 CrossRef citations
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Early pregnancy exposure to selective serotonin reuptake inhibitors, risks of major structural malformations, and hypothesized teratogenic mechanisms

Salvatore Gentile MD PhD

Pages: 1585-1597

Published online: 01 Jul 2015

AbstractforEarly pregnancy exposure to selective serotonin reuptake inhibitors, risks of major structural malformations, and hypothesized teratogenic mechanisms | Full Text | References | PDF (268.6 KB)

605 Views
14 CrossRef citations
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The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19

Yao Yang, Joshua P Lewis, Jean-Sébastien Hulot & Stuart A Scott

Pages: 1599-1617

Published online: 14 Jul 2015

AbstractforThe pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19 | Full Text | References | PDF (563.7 KB)

393 Views
18 CrossRef citations
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Role of organic cation transporters in drug–drug interaction

Hermann Koepsell

Pages: 1619-1633

Published online: 24 Jul 2015

AbstractforRole of organic cation transporters in drug–drug interaction | Full Text | References | PDF (605 KB)

1349 Views
73 CrossRef citations
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Drug Evaluation

Efficacy, pharmacokinetic and pharmacodynamic profile of belimumab for systemic lupus erythematosus

Natasha P Jordan (Consultant Rheumatologist) MB MRCP(I) PhD & David P D’Cruz (Consultant Rheumatologist) MD FRCP(UK)

Pages: 1635-1645

Published online: 01 Sep 2015

AbstractforEfficacy, pharmacokinetic and pharmacodynamic profile of belimumab for systemic lupus erythematosus | Full Text | References | PDF (246.3 KB)

784 Views
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Pharmacokinetics, pharmacodynamics and clinical efficacy of pertuzumab in breast cancer therapy

Andrea Rocca MD, Daniele Andreis BSc, Anna Fedeli MD, Roberta Maltoni MD, Samanta Sarti MD, Lorenzo Cecconetto MD, Elisabetta Pietri MD, Alessio Schirone MD, Sara Bravaccini PhD, Patrizia Serra BSc, Alberto Farolfi MD & Dino Amadori MD

Pages: 1647-1663

Published online: 26 Aug 2015

AbstractforPharmacokinetics, pharmacodynamics and clinical efficacy of pertuzumab in breast cancer therapy | Full Text | References | PDF (499.4 KB)

866 Views
10 CrossRef citations
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Dosing of rivaroxaban by indication: getting the right dose for the patient

Gines Escolar, Xavier Carne & Eduardo Arellano-Rodrigo

Pages: 1665-1677

Published online: 31 Aug 2015

AbstractforDosing of rivaroxaban by indication: getting the right dose for the patient | Full Text | References | PDF (462.1 KB)

788 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.11, Iss.10, 2015)

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