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Volume 11, Issue 5

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 5 (2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 5 (2015)

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Vol 20, 2024 Vol 19, 2023 Vol 18, 2022 Vol 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Volume 11, 2015 Vol 10, 2014 Vol 9, 2013 Vol 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005

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Editorial

Drug transport and metabolism of novel anticancer drugs

Godefridus J Peters & Richard J Honeywell

Pages: 661-663

Published online: 04 May 2015

First Page PreviewforDrug transport and metabolism of novel anticancer drugs | Full Text | References | PDF (121.4 KB)

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Free Access

Review

Role of cytidine deaminase in toxicity and efficacy of nucleosidic analogs

Cindy Serdjebi, Gérard Milano & Joseph Ciccolini

Pages: 665-672

Published online: 13 Dec 2014

AbstractforRole of cytidine deaminase in toxicity and efficacy of nucleosidic analogs | Full Text | References | PDF (228.2 KB)

671 Views
49 CrossRef citations
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Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance

Anna Wojtuszkiewicz, Yehuda G Assaraf, Marielle JP Maas, Gertjan JL Kaspers, Gerrit Jansen & Jacqueline Cloos

Pages: 673-689

Published online: 13 Dec 2014

AbstractforPre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance | Full Text | References | PDF (707.2 KB)

586 Views
36 CrossRef citations
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Metabolism of the taxanes including nab-paclitaxel

Markus Joerger (Assistant Professor) MD PhD (ClinPharm)

Pages: 691-702

Published online: 14 Nov 2014

AbstractforMetabolism of the taxanes including nab-paclitaxel | Full Text | References | PDF (281.7 KB)

916 Views
24 CrossRef citations
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Physicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters

Candido G Da Silva, Richard J Honeywell, Henk Dekker & Godefridus J Peters (Professor) PhD

Pages: 703-717

Published online: 29 Jan 2015

AbstractforPhysicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters | Full Text | References | PDF (579.9 KB)

376 Views
15 CrossRef citations
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Pharmacogenetics and breast cancer management: current status and perspectives

Joseph Ciccolini, Raphaelle Fanciullino, Cindy Serdjebi & Gérard Milano

Pages: 719-729

Published online: 18 Feb 2015

AbstractforPharmacogenetics and breast cancer management: current status and perspectives | Full Text | References | PDF (340.3 KB)

353 Views
12 CrossRef citations
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Pharmacokinetic and toxicity considerations in the use of neoadjuvant chemotherapy for bladder cancer

Vivek Narayan (Fellow in Hematology/Oncology) MD & David Vaughn (Professor of Medicine) MD

Pages: 731-742

Published online: 21 Jan 2015

AbstractforPharmacokinetic and toxicity considerations in the use of neoadjuvant chemotherapy for bladder cancer | Full Text | References | PDF (279.2 KB)

247 Views
11 CrossRef citations
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Physiologically based pharmacokinetic and pharmacodynamic modeling in cancer drug development: status, potential and gaps

Michael Block

Pages: 743-756

Published online: 04 May 2015

AbstractforPhysiologically based pharmacokinetic and pharmacodynamic modeling in cancer drug development: status, potential and gaps | Full Text | References | PDF (489.5 KB)

741 Views
15 CrossRef citations
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Effect of age on drug metabolism in women with breast cancer

Jasmeet C Singh MD & Stuart M Lichtman MD

Pages: 757-766

Published online: 04 May 2015

AbstractforEffect of age on drug metabolism in women with breast cancer | Full Text | References | PDF (249.2 KB)

215 Views
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Mathematical modeling analysis of intratumoral disposition of anticancer agents and drug delivery systems

Hen Popilski & David Stepensky

Pages: 767-784

Published online: 26 Mar 2015

AbstractforMathematical modeling analysis of intratumoral disposition of anticancer agents and drug delivery systems | Full Text | References | PDF (616.6 KB)

331 Views
9 CrossRef citations
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Effect of glucuronidation on transport and tissue accumulation of tyrosine kinase inhibitors: consequences for the clinical management of sorafenib and regorafenib

Camille Tlemsani MD, Olivier Huillard, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Anatole Cessot, Benoit Blanchet, Audrey Thomas-Schoemann, Romain Coriat, Jean-Philippe Durand, Julie Giroux, Jérôme Alexandre & François Goldwasser

Pages: 785-794

Published online: 25 Mar 2015

AbstractforEffect of glucuronidation on transport and tissue accumulation of tyrosine kinase inhibitors: consequences for the clinical management of sorafenib and regorafenib | Full Text | References | PDF (373.6 KB)

626 Views
27 CrossRef citations
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Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism

Helena Joyce PhD, Andrew McCann BSc, Martin Clynes PhD & Annemarie Larkin PhD

Pages: 795-809

Published online: 02 Apr 2015

AbstractforInfluence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism | Full Text | References | PDF (561.8 KB)

611 Views
52 CrossRef citations
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Drug Evaluation

Pharmacogenomics of fluorouracil-based chemotherapy toxicity

Satoshi Matsusaka MD PhD & Heinz-Josef Lenz MD

Pages: 811-821

Published online: 23 Mar 2015

AbstractforPharmacogenomics of fluorouracil-based chemotherapy toxicity | Full Text | References | PDF (367.5 KB)

741 Views
34 CrossRef citations
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Evaluating the pharmacokinetics and pharmacodynamics of everolimus for treating breast cancer

Andrea Gombos, Philippe Barthélémy & Ahmad Awada

Pages: 823-834

Published online: 07 Feb 2015

AbstractforEvaluating the pharmacokinetics and pharmacodynamics of everolimus for treating breast cancer | Full Text | References | PDF (455.4 KB)

580 Views
2 CrossRef citations
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Pharmacokinetics of crizotinib in NSCLC patients

Gerhard Hamilton, Barbara Rath & Otto Burghuber

Pages: 835-842

Published online: 03 Mar 2015

AbstractforPharmacokinetics of crizotinib in NSCLC patients | Full Text | References | PDF (254.7 KB)

930 Views
35 CrossRef citations
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Metabolism and pharmacokinetics of radium-223 in prostate cancer

Oladapo Yeku MD PhD & Susan F Slovin MD PhD

Pages: 843-849

Published online: 04 Mar 2015

AbstractforMetabolism and pharmacokinetics of radium-223 in prostate cancer | Full Text | References | PDF (325.5 KB)

366 Views
3 CrossRef citations
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Expert Opinion on Drug Metabolism & Toxicology (Vol.11, Iss.5, 2015)

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