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Volume 6, Issue 5

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 6, Issue 5 (2010)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 6, Issue 5 (2010)

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Reviews

Article

Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury: a review

Dolores B Njoku (Associate Professor) MD

Pages: 519-531

Published online: 18 Feb 2010

AbstractforSuppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury: a review | Full Text | References | PDF (335.9 KB)

274 Views
23 CrossRef citations
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Article

Assessment of in silico models for fraction of unbound drug in human liver microsomes

Hua Gao (Associate Research Fellow) PhD, Stefanus J Steyn (Associate Research Fellow) PhD, George Chang (Principal Scientist) PhD & Jing Lin (Senior Principal Scientist) PhD

Pages: 533-542

Published online: 16 Mar 2010

AbstractforAssessment of in silico models for fraction of unbound drug in human liver microsomes | Full Text | References | PDF (506.2 KB)

662 Views
25 CrossRef citations
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Article

Overview of extracellular microvesicles in drug metabolism

Javier Conde-Vancells, Esperanza Gonzalez, Shelly C Lu, Jose M Mato (Professor) & Juan M Falcon-Perez PhD

Pages: 543-554

Published online: 02 Mar 2010

AbstractforOverview of extracellular microvesicles in drug metabolism | Full Text | References | PDF (335.2 KB)

299 Views
29 CrossRef citations
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Article

Bis(monoacylglycerol)phosphate as a non-invasive biomarker to monitor the onset and time-course of phospholipidosis with drug-induced toxicities

Elizabeth A Tengstrand MS, Gerald T Miwa PhD & Frank Y Hsieh PhD

Pages: 555-570

Published online: 07 Apr 2010

AbstractforBis(monoacylglycerol)phosphate as a non-invasive biomarker to monitor the onset and time-course of phospholipidosis with drug-induced toxicities | Full Text | References | PDF (554.6 KB)

1041 Views
44 CrossRef citations
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Article

ABC transporters in human lymphocytes: expression, activity and role, modulating factors and consequences for antiretroviral therapies

Carole Giraud, Sandra Manceau & Jean-Marc Treluyer

Pages: 571-589

Published online: 02 Apr 2010

AbstractforABC transporters in human lymphocytes: expression, activity and role, modulating factors and consequences for antiretroviral therapies | Full Text | References | PDF (418.6 KB)

231 Views
19 CrossRef citations
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Article

From sequence and structure of sulfotransferases and dihydropyrimidinases to an understanding of their mechanisms of action and function

Ching-Chen Hsu, Lu-Yi Lu & Yuh-Shyong Yang

Pages: 591-601

Published online: 19 Apr 2010

AbstractforFrom sequence and structure of sulfotransferases and dihydropyrimidinases to an understanding of their mechanisms of action and function | Full Text | References | PDF (545.8 KB)

119 Views
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Article

P-glycoprotein related drug interactions: clinical importance and a consideration of disease states

Caroline A Lee (Research Fellow) PhD, Jack A Cook (Vice President) PhD, Eric L Reyner (Senior Principal Scientist) BS & Dennis A Smith (Academic Research Fellow) PhD

Pages: 603-619

Published online: 19 Apr 2010

AbstractforP-glycoprotein related drug interactions: clinical importance and a consideration of disease states | Full Text | References | PDF (469.6 KB)

839 Views
60 CrossRef citations
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Article

Efflux and uptake transporters as determinants of statin response

Alice C Rodrigues

Pages: 621-632

Published online: 05 Apr 2010

AbstractforEfflux and uptake transporters as determinants of statin response | Full Text | References | PDF (281.1 KB)

867 Views
57 CrossRef citations
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Article

Effects of dietary factors on levodopa pharmacokinetics

Nelida Fernandez, Juan J Garcia, Maria Jose Diez, Ana M Sahagun, Raquel Díez & Matilde Sierra

Pages: 633-642

Published online: 13 Apr 2010

AbstractforEffects of dietary factors on levodopa pharmacokinetics | Full Text | References | PDF (212 KB)

513 Views
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Drug Evaluation

Article

Glatiramer acetate and the glatiramoid class of immunomodulator drugs in multiple sclerosis: an update

Kenneth P Johnson (Professor Emeritus) MD

Pages: 643-660

Published online: 19 Apr 2010

AbstractforGlatiramer acetate and the glatiramoid class of immunomodulator drugs in multiple sclerosis: an update | Full Text | References | PDF (404 KB)

270 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.6, Iss.5, 2010)

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