Free Radical Research, Volume 56, Issue 2 (2022)

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Free Radical Research, Volume 56, Issue 2 (2022)

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Original Articles

Article
Mutyh deficiency downregulates mitochondrial fusion proteins and causes cardiac dysfunction via α-ketoglutaric acid reduction with oxidative stress
Jingwen Chen, Xin Wu, Yanyi Wang, Yunfeng Pan, Yan Ren, Yusaku Nakabeppu, Yimei Fan & Yaping Wang
Pages: 129-142
Published online: 28 Mar 2022
AbstractforMutyh deficiency downregulates mitochondrial fusion proteins and causes cardiac dysfunction via α-ketoglutaric acid reduction with oxidative stress | Full Text | References | PDF (2.8 MB) | EPUB
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Article
HIF-1α protects osteoblasts from ROS-induced apoptosis
Xiaohui Wang, Lili Wei, Qiaochuan Li & Yongrong Lai
Pages: 143-153
Published online: 05 Apr 2022
AbstractforHIF-1α protects osteoblasts from ROS-induced apoptosis | Full Text | References | PDF (1.9 MB) | EPUB
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Open Access
Article
The Val16Ala MnSOD gene polymorphism is associated with hypertension in self-declared black individuals
Lyana Feijoó Berro, Patricia Maurer, Debora Rubio, Vanessa Retamoso, Lauren Santos, Vanusa Manfredini & Jacqueline da Costa Escobar Piccoli
Pages: 154-162
Published online: 15 Apr 2022
AbstractforThe Val16Ala MnSOD gene polymorphism is associated with hypertension in self-declared black individuals | Full Text | References | PDF (803.7 KB)
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Article
Hypoxia induces proliferation via NOX4-Mediated oxidative stress and TGF-β3 signaling in uterine leiomyoma cells
Mariko Miyashita-Ishiwata, Malak El Sabeh, Lauren D. Reschke, Sadia Afrin & Mostafa A. Borahay
Pages: 163-172
Published online: 15 Apr 2022
AbstractforHypoxia induces proliferation via NOX4-Mediated oxidative stress and TGF-β3 signaling in uterine leiomyoma cells | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
A cartoon illustrating the mechanism by which hypoxia induces NOX4-mediated leiomyoma cell proliferation via ROS generation and TGF-β3 pathway. HIF-1α, hypoxia inducible factor 1 alpha; TGF-β3, transforming growth factor beta 3; TGFβR, transforming growth factor beta receptor; NOX4, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4; ROS, reactive oxygen species.
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Article
Ferulic acid protects renal tubular epithelial cells against anoxia/reoxygenation injury mediated by AMPKα1
Tianpeng Chen, Li Niu, Liang Wang, Qing Zhou, Xiaoyu Zhao, Songqing Lai, Xinlan He, Huan He & Ming He
Pages: 173-184
Published online: 20 Apr 2022
AbstractforFerulic acid protects renal tubular epithelial cells against anoxia/reoxygenation injury mediated by AMPKα1 | Full Text | References | PDF (2.5 MB) | EPUB
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Article
Metabolomics analysis of the effects of quercetin on Cd-induced hepatotoxicityin rats
Youwei Xin, Yali Hou, Jingnan Zhang, Tingting Ding, Zhiyu Guan, Dongyan Zhang, Dan Wang, Siqi Jia, Siqi Li & Xiujuan Zhao
Pages: 185-195
Published online: 29 Apr 2022
AbstractforMetabolomics analysis of the effects of quercetin on Cd-induced hepatotoxicityin rats | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
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Article
Antioxidant activity of erlotinib and gefitinib: theoretical and experimental insights
Safna Hussan K. P, Thekkekara D. Babu, Pareeth C. M, Greena Joshy, Deepu Mathew & M. Shahin Thayyil
Pages: 196-208
Published online: 05 May 2022
AbstractforAntioxidant activity of erlotinib and gefitinib: theoretical and experimental insights | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway
Yajun Qi, Shuang Fu, Donggen Pei, Qilu Fang, Wenxiu Xin, Xiaohong Yuan, Yingying Cao, Qi Shu, Xiufang Mi & Fang Luo
Pages: 209-221
Published online: 25 Apr 2022
AbstractforLuteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway | Full Text | References | PDF (2.7 MB) | EPUB
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Article
Formation of radicals in irradiated maltose – the role of hydrogen bonding with water
Seiko Nakagawa
Pages: 222-227
Published online: 08 May 2022
AbstractforFormation of radicals in irradiated maltose – the role of hydrogen bonding with water | Full Text | References | PDF (945.5 KB) | EPUB
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