Journal of Immunotoxicology, Volume 17, Issue 1 (2020)

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Journal of Immunotoxicology, Volume 17, Issue 1 (2020)

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Research Articles

Article
Altered levels of complement components associated with non-immediate drug hypersensitivity reactions
Feng Wang, Liping Huang, Junfeng Yu, Dandan Zang, Liangping Ye & Qixing Zhu
Pages: 1-9
Published online: 04 Dec 2019
AbstractforAltered levels of complement components associated with non-immediate drug hypersensitivity reactions | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 2503 Views
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Article
Mucosal-associated invariant T-Cell (MAIT) activation is altered by chlorpyrifos- and glyphosate-treated commensal gut bacteria
Anne Mendler, Florian Geier, Sven-Bastiaan Haange, Arkadiusz Pierzchalski, Jannike Lea Krause, Ivonne Nijenhuis, Jean Froment, Nico Jehmlich, Urs Berger, Grit Ackermann, Ulrike Rolle-Kampczyk, Martin von Bergen & Gunda Herberth
Pages: 10-20
Published online: 07 Jan 2020
AbstractforMucosal-associated invariant T-Cell (MAIT) activation is altered by chlorpyrifos- and glyphosate-treated commensal gut bacteria | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 3610 Views
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Open Access
Article
Activation of aryl hydrocarbon receptor (AhR) in mesenchymal stem cells modulates macrophage polarization in asthma
Zhuang Cui, Yuan Feng, Danqing Li, Taoping Li, Peisong Gao & Ting Xu
Pages: 21-30
Published online: 10 Jan 2020
AbstractforActivation of aryl hydrocarbon receptor (AhR) in mesenchymal stem cells modulates macrophage polarization in asthma | Full Text | References | PDF (2.3 MB) | EPUB
  • 4260 Views
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Article
KMRC011, an agonist of toll-like receptor 5, mitigates irradiation-induced tissue damage and mortality in cynomolgus monkeys
Hong-Soo Lee, Doo-Wan Cho, Ji-Seok Han, Su-Cheol Han, Sang Keun Woo, Soo-Youn Jun, Woo-Jong Lee, Susie Yoon, Son-Il Pak, Sang-Jin Lee, Eunsol Seong & Eun-Jung Park
Pages: 31-42
Published online: 03 Feb 2020
AbstractforKMRC011, an agonist of toll-like receptor 5, mitigates irradiation-induced tissue damage and mortality in cynomolgus monkeys | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 1600 Views
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Open Access
Article
Colostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1
Sajad Najafi, Gholamreza Mohammadi, Mehrdad Mohri, Saman Hosseinkhani & Jalil Mehrzad
Pages: 43-50
Published online: 03 Mar 2020
AbstractforColostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1 | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 1314 Views
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Open Access
Article
Cross-company evaluation of the human lymphocyte activation assay
Mark Collinge, Patricia Schneider, Dingzhou Li, Stanley Parish, Carolyne Dumont, Wendy Freebern, Joseph Ghanime, Fanny Guimont-Derochers, Anja Langenkamp, Jose Lebron, Nianyu Li, Celine Marban, Lisa Plitnick & Jennifer Wheeler
Pages: 51-58
Published online: 03 Mar 2020
AbstractforCross-company evaluation of the human lymphocyte activation assay | Full Text | References | PDF (1.4 MB) | EPUB
  • 2397 Views
  • 4 CrossRef citations
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Article
Immunostimulatory effects on THP-1 cells by peptide or protein pharmaceuticals associated with injection site reactions
Eri Hamamura-Yasuno, Tetsuo Aida, Yoshimi Tsuchiya & Kazuhiko Mori
Pages: 59-66
Published online: 24 Feb 2020
AbstractforImmunostimulatory effects on THP-1 cells by peptide or protein pharmaceuticals associated with injection site reactions | Full Text | References | PDF (1.3 MB) | EPUB
  • 3062 Views
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Open Access
Article
Summary of a workshop on preclinical and translational safety assessment of CD3 bispecifics
Cris Kamperschroer, Jacintha Shenton, Hervé Lebrec, John K. Leighton, Paul A. Moore & Oliver Thomas
Pages: 67-85
Published online: 26 Feb 2020
AbstractforSummary of a workshop on preclinical and translational safety assessment of CD3 bispecifics | Full Text | References | PDF (1.4 MB) | EPUB
  • 12177 Views
  • 28 CrossRef citations
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Open Access
Article
Environmental pollutants modulate RNA and DNA virus-activated miRNA-155 expression and innate immune system responses: Insights into new immunomodulative mechanisms*
Alexander Badry, Veerle L. B. Jaspers & Courtney A. Waugh
Pages: 86-93
Published online: 01 Apr 2020
AbstractforEnvironmental pollutants modulate RNA and DNA virus-activated miRNA-155 expression and innate immune system responses: Insights into new immunomodulative mechanisms* | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 2430 Views
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Open Access
Article
In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish
Drake W. Phelps, Ashley A. Fletcher, Ivan Rodriguez-Nunez, Michele R. Balik-Meisner, Debra A. Tokarz, David M. Reif, Dori R. Germolec & Jeffrey A. Yoder
Pages: 94-104
Published online: 14 May 2020
AbstractforIn vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2467 Views
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Open Access
Article
Circulating inflammatory markers in cervical cancer patients and healthy controls
Agne Vitkauskaite, Daiva Urboniene, Joana Celiesiute, Kristina Jariene, Erika Skrodeniene, Ruta Jolanta Nadisauskiene & Daiva Vaitkiene
Pages: 105-109
Published online: 04 May 2020
AbstractforCirculating inflammatory markers in cervical cancer patients and healthy controls | Full Text | References | PDF (497.1 KB) | EPUB
  • 3173 Views
  • 15 CrossRef citations
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Open Access
Article
MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities
Marc A. Lafleur, Jonathan Werner, Madeline Fort, Edward K. Lobenhofer, Mercedesz Balazs & Ana Goyos
Pages: 110-121
Published online: 11 Jun 2020
AbstractforMRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities | Full Text | References | PDF (1.3 MB) | EPUB
  • 5567 Views
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Open Access
Article
Potential classification of chemical immunologic response based on gene expression profiles
Stacey E. Anderson, Rachel Baur, Michael Kashon, Ewa Lukomska, Lisa Weatherly & Hillary L. Shane
Pages: 122-134
Published online: 25 May 2020
AbstractforPotential classification of chemical immunologic response based on gene expression profiles | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1479 Views
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Open Access
Article
Prenatal arsenic exposure interferes in postnatal immunocompetence despite an absence of ongoing arsenic exposure
Mainak Chakraborty & Moumita Bhaumik
Pages: 135-143
Published online: 13 Jun 2020
AbstractforPrenatal arsenic exposure interferes in postnatal immunocompetence despite an absence of ongoing arsenic exposure | Full Text | References | PDF (1.7 MB) | EPUB
  • 1898 Views
  • 5 CrossRef citations
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Article
Effect of lead exposure and nutritional iron-deficiency on immune response: A vaccine challenge study in rats
Srinivasa Reddy Yathapu, Narendra Babu Kondapalli, Sarath Babu Srivalliputturu, Rajkumar Hemalatha & Dinesh Kumar Bharatraj
Pages: 144-152
Published online: 23 Jun 2020
AbstractforEffect of lead exposure and nutritional iron-deficiency on immune response: A vaccine challenge study in rats | Full Text | References | PDF (1.5 MB) | EPUB
  • 2373 Views
  • 4 CrossRef citations
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Open Access
Article
Organic dust-induced lung injury and repair: Bi-directional regulation by TNFα and IL-10
T. A. Wyatt, M. Nemecek, D. Chandra, J. M. DeVasure, A. J. Nelson, D. J. Romberger & J. A. Poole
Pages: 153-162
Published online: 07 Jul 2020
AbstractforOrganic dust-induced lung injury and repair: Bi-directional regulation by TNFα and IL-10 | Full Text | References | PDF (1.6 MB) | EPUB
  • 1871 Views
  • 9 CrossRef citations
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Open Access
Article
The impact and toxicity of glyphosate and glyphosate-based herbicides on health and immunity
Cindy Peillex & Martin Pelletier
Pages: 163-174
Published online: 08 Sep 2020
AbstractforThe impact and toxicity of glyphosate and glyphosate-based herbicides on health and immunity | Full Text | References | PDF (1.9 MB) | EPUB
  • 53516 Views
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Article
A T-cell-dependent antibody response study using a murine surrogate anti-PD-1 monoclonal antibody as an alternative to a non-human primate model
Lisa M. Plitnick, Beth Hutchins, Sheri Dubey, Nianyu Li, Rupesh P. Amin, Stephanie Born, Ruban Mangadu, Joseph H. Phillips, Venkataraman Sriram & Danuta J. Herzyk
Pages: 175-185
Published online: 20 Oct 2020
AbstractforA T-cell-dependent antibody response study using a murine surrogate anti-PD-1 monoclonal antibody as an alternative to a non-human primate model | Full Text | References | PDF (1.8 MB) | EPUB
  • 3637 Views
  • 3 CrossRef citations
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Article
Cadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways
Thitima Kasemsuk, Suttinee Phuagkhaopong, Ruedeemars Yubolphan, Norapat Rungreangplangkool & Pornpun Vivithanaporn
Pages: 186-193
Published online: 19 Oct 2020
AbstractforCadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 1917 Views
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Article
Immunotoxicity studies of trans-resveratrol in male B6C3F1/N mice
Madelyn C. Huang, Kimber L. White Jr., Susan A. Elmore, Tai L. Guo & Dori Germolec
Pages: 194-201
Published online: 20 Nov 2020
AbstractforImmunotoxicity studies of trans-resveratrol in male B6C3F1/N mice | Full Text | References | PDF (1.2 MB) | EPUB
  • 1773 Views
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Article
Local inflammatory marker production in Lithuanian patients with chronic rhinosinusitis with nasal polyps
Justinas Vaitkus, Astra Vitkauskiene, Vilte Matuseviciute, Albinas Naudziunas, Nora Siupsinskiene & Saulius Vaitkus
Pages: 202-206
Published online: 12 Dec 2020
AbstractforLocal inflammatory marker production in Lithuanian patients with chronic rhinosinusitis with nasal polyps | Full Text | References | PDF (501 KB) | EPUB
  • 929 Views
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