Leukemia & Lymphoma, Volume 61, Issue 8 (2020)

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Leukemia & Lymphoma, Volume 61, Issue 8 (2020)

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Commentaries

Exhausted and outnumbered: CD4+ T cells in the myeloma battlefield
Elisabet E. Manasanch & Morie A. Gertz
Pages: 1777-1779
Published online: 16 Jun 2020
First Page PreviewforExhausted and outnumbered: CD4+ T cells in the myeloma battlefield | Full Text | References | PDF (304.7 KB) | EPUB
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The gift that keeps on giving: lenalidomide maintenance after second autologous stem cell transplant in multiple myeloma
Cara A. Rosenbaum
Pages: 1780-1783
Published online: 04 Aug 2020
First Page PreviewforThe gift that keeps on giving: lenalidomide maintenance after second autologous stem cell transplant in multiple myeloma | Full Text | References | PDF (361.1 KB) | EPUB
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Reviews

Review
Burkitt lymphoma: bridging the gap between advances in molecular biology and therapy
Adam S. Zayac & Adam J. Olszewski
Pages: 1784-1796
Published online: 07 Apr 2020
AbstractforBurkitt lymphoma: bridging the gap between advances in molecular biology and therapy | Full Text | References | PDF (1.5 MB) | EPUB
  • 856 Views
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Review
Management of myelofibrosis after ruxolitinib failure
Prithviraj Bose & Srdan Verstovsek
Pages: 1797-1809
Published online: 16 Apr 2020
AbstractforManagement of myelofibrosis after ruxolitinib failure | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 676 Views
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Original Articles

Article
Fatty acid synthase and adenosine monophosphate-activated protein kinase regulate cell survival and drug sensitivity in diffuse large B-cell lymphoma
Grace K. Gifford, Andrew J. Gifford, Qian Chen, Yandong Shen, Sara Gabrielli, Anthony J. Gill, William S. Stevenson & Oliver Giles Best
Pages: 1810-1822
Published online: 04 Apr 2020
AbstractforFatty acid synthase and adenosine monophosphate-activated protein kinase regulate cell survival and drug sensitivity in diffuse large B-cell lymphoma | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 234 Views
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Article
Feasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis
María Laura Fox, Irene García-Cadenas, Ariadna Martínez Pérez, Guillermo Villacampa, José Luis Piñana, Guillermo Ortí, Juan Montoro, Elisa Roldán, Anna Bosch Vilaseca, Rodrigo Martino, Olga Salamero, Silvana Saavedra, Juan Carlos Hernandez-Boluda, Albert Esquirol, Jordi Sierra, Jaime Sanz, Carlos Solano, Francesc Bosch, Pere Barba & David Valcarcel
Pages: 1823-1832
Published online: 11 Jul 2020
AbstractforFeasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 223 Views
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Article
The geriatric syndrome of sarcopenia impacts allogeneic hematopoietic cell transplantation outcomes in older lymphoma patients
Richard J. Lin, Laure Michaud, Stephanie M. Lobaugh, Reiko Nakajima, Audrey Mauguen, Theresa A. Elko, Josel D. Ruiz, Molly A. Maloy, Craig S. Sauter, Parastoo B. Dahi, Miguel-Angel Perales, Gunjan L. Shah, Nerea Castillo Flores, Míriam Sanchez-Escamilla, Ana Alarcón Tomas, Lucrecia Yáñez San Segundo, Christina Cho, Ioannis Politikos, Soo Jung Kim, Beatriz Korc-Grodzicki, Sean M. Devlin, Michael Scordo, Heiko Schöder, Sergio A. Giralt & Paul A. Hamlin
Pages: 1833-1841
Published online: 31 Mar 2020
AbstractforThe geriatric syndrome of sarcopenia impacts allogeneic hematopoietic cell transplantation outcomes in older lymphoma patients | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 279 Views
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Article
A prospective, crossover randomized trial of the optimal timing for leucovorin rescue after high-dose methotrexate management in adult non-Hodgkin’s lymphoma patients
Chen Peng, Xueying Li, He Huang, Tingzhi Liu, Chengcheng , Zhao Wang, Xiaojie Fang, Huangming Hong, Fangfang Li, Quanguang Ren, Shu Liu, Ying Tian & Tongyu Lin
Pages: 1842-1849
Published online: 22 Apr 2020
AbstractforA prospective, crossover randomized trial of the optimal timing for leucovorin rescue after high-dose methotrexate management in adult non-Hodgkin’s lymphoma patients | Full Text | References | PDF (960.8 KB) | EPUB
  • 216 Views
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Article
Health-related quality-of-life results from the phase 3 OPTIMISMM study: pomalidomide, bortezomib, and low-dose dexamethasone versus bortezomib and low-dose dexamethasone in relapsed or refractory multiple myeloma
Katja Weisel, Meletios Dimopoulos, Philippe Moreau, Munci Yagci, Alessandra Larocca, Abraham S. Kanate, Filiz Vural, Nicola Cascavilla, Supratik Basu, Peter Johnson, Peter Byeff, Marek Hus, Paula Rodríguez-Otero, Ercan Muelduer, Pekka Anttila, Patrick J. Hayden, Maria-Theresa Krauth, Paulo Lucio, Dina Ben-Yehuda, Larisa Mendeleeva, Shien Guo, Xin Yu, Lara Grote, Tsvetan Biyukov, Sujith Dhanasiri & Paul Richardson
Pages: 1850-1859
Published online: 09 Apr 2020
AbstractforHealth-related quality-of-life results from the phase 3 OPTIMISMM study: pomalidomide, bortezomib, and low-dose dexamethasone versus bortezomib and low-dose dexamethasone in relapsed or refractory multiple myeloma | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 851 Views
  • 10 CrossRef citations
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Article
An open-label, pharmacokinetic study of lenalidomide and dexamethasone therapy in previously untreated multiple myeloma (MM) patients with various degrees of renal impairment – validation of official dosing guidelines
Christine I. Chen, Yanshuo Cao, Suzanne Trudel, Donna E. Reece, Vishal Kukreti, Rodger Tiedemann, Anca Prica, Harminder Paul, Lisa W. Le, Olga Levina, Sumeet Kakar, Anthea Lau, Hongzhuan Chen & Eric Chen
Pages: 1860-1868
Published online: 31 May 2020
AbstractforAn open-label, pharmacokinetic study of lenalidomide and dexamethasone therapy in previously untreated multiple myeloma (MM) patients with various degrees of renal impairment – validation of official dosing guidelines | Full Text | References | PDF (849.2 KB) | EPUB
  • 296 Views
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Article
Low absolute CD4+ T cell counts in peripheral blood predict poor prognosis in patients with newly diagnosed multiple myeloma
Yan Gu, Yuanyuan Jin, Jie Ding, Wu Yujie, Qinglin Shi, Xiaoyan Qu, Sishu Zhao, Jianyong Li & Chen Lijuan
Pages: 1869-1876
Published online: 23 Apr 2020
AbstractforLow absolute CD4+ T cell counts in peripheral blood predict poor prognosis in patients with newly diagnosed multiple myeloma | Full Text | References | PDF (821.4 KB) | EPUB
  • 255 Views
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Article
Lenalidomide maintenance after second autologous stem cell transplant improves overall survival in multiple myeloma
Dipenkumar Modi, Jie Chi, Seongho Kim, Lois Ayash, Asif Alavi, Andrew Kin, Voravit Ratanatharathorn, Joseph P. Uberti & Abhinav Deol
Pages: 1877-1884
Published online: 09 Apr 2020
AbstractforLenalidomide maintenance after second autologous stem cell transplant improves overall survival in multiple myeloma | Full Text | References | PDF (891 KB) | EPUB | Supplemental
  • 337 Views
  • 4 CrossRef citations
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Article
Different MAF translocations confer similar prognosis in newly diagnosed multiple myeloma patients
Sarah Goldman-Mazur, Artur Jurczyszyn, Jorge J. Castillo, Anna Waszczuk-Gajda, Norbert Grząśko, Jakub Radocha, Max Bittrich, Klaus Martin Kortüm, Alessandro Gozzetti, Lidia Usnarska-Zubkiewicz, Julio D. Valls, David S. Jayabalan, Ruben Niesvizky, Julia Kelman, Daniel Coriu, Laura Rosiñol, Łukasz Szukalski, Veronica González-Calle, María-Victoria Mateos, Krzysztof Jamroziak, Iwona Hus, Irit Avivi, Yael Cohen, Piotr Mazur, Anna Suska, Aimee Chappell, Deepu Madduri, Saurabh Chhabra, Ariel Kleman, Parameswaran Hari, Michel Delforge, Paweł Robak, Massimo Gentile, Izabela Kozłowska, Stuart L. Goldberg, Jacek Czepiel, Monika Długosz-Danecka, Rebecca Silbermann, Adam J. Olszewski, Peter Barth, Gabor Mikala, Chor S. Chim & David H. Vesole
Pages: 1885-1893
Published online: 19 Apr 2020
AbstractforDifferent MAF translocations confer similar prognosis in newly diagnosed multiple myeloma patients | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 278 Views
  • 3 CrossRef citations
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Article
The prognostic value of the controlling nutritional status score in patients with multiple myeloma
Takahiro Kamiya, Chisako Ito, Yuriko Fujita, Shinji Ogura, Kota Mizuno, Aki Sakurai, Yoshinobu Aisa & Tomonori Nakazato
Pages: 1894-1900
Published online: 19 Apr 2020
AbstractforThe prognostic value of the controlling nutritional status score in patients with multiple myeloma | Full Text | References | PDF (1.1 MB) | EPUB
  • 256 Views
  • 11 CrossRef citations
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Article
A sequential two-stage dose escalation study of eltrombopag in patients with myelodysplastic syndrome and thrombocytopenia after hypomethylating agent failure
Vu H. Duong, Najla Al Ali, Ling Zhang, Eric Padron, David Sallman, Jeffrey E. Lancet, Alan F. List & Rami S. Komrokji
Pages: 1901-1907
Published online: 19 Apr 2020
AbstractforA sequential two-stage dose escalation study of eltrombopag in patients with myelodysplastic syndrome and thrombocytopenia after hypomethylating agent failure | Full Text | References | PDF (584.5 KB) | EPUB
  • 413 Views
  • 3 CrossRef citations
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Article
Healthcare resource utilization in myeloproliferative neoplasms: a population-based study from Ontario, Canada
Aniket Bankar, Haoyu Zhao, Javaid Iqbal, Ruth Coxford, Matthew C. Cheung, Lee Mozessohn, Craig C. Earle & Vikas Gupta
Pages: 1908-1919
Published online: 23 Apr 2020
AbstractforHealthcare resource utilization in myeloproliferative neoplasms: a population-based study from Ontario, Canada | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 2523 Views
  • 9 CrossRef citations
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Open Access
Article
Supportive care medications coinciding with chemotherapy among children with hematologic malignancy
Eman Biltaji, Elena Y. Enioutina, Venkata Yellepeddi, Joseph E. Rower, Catherine M. T. Sherwin, Robert M. Ward, Richard S. Lemons & Jonathan E. Constance
Pages: 1920-1931
Published online: 07 Apr 2020
AbstractforSupportive care medications coinciding with chemotherapy among children with hematologic malignancy | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 182 Views
  • 3 CrossRef citations
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Article
Induction of leukemic stem cell differentiation by aryl hydrocarbon receptor agonist and synergy with gilteritinib in FLT3-ITD + acute myeloid leukemia
Heejoo Han, Dong-Yeop Shin, Dongchan Kim, Hyungsuk Kim, Chansup Lee, Youngil Koh, Junshik Hong & Sung-Soo Yoon
Pages: 1932-1942
Published online: 06 May 2020
AbstractforInduction of leukemic stem cell differentiation by aryl hydrocarbon receptor agonist and synergy with gilteritinib in FLT3-ITD + acute myeloid leukemia | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 722 Views
  • 3 CrossRef citations
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Article
Results of a Phase 1/2a dose–escalation study of FF-10501-01, an IMPDH inhibitor, in patients with acute myeloid leukemia or myelodysplastic syndromes
Guillermo Garcia-Manero, Naveen Pemmaraju, Yesid Alvarado, Kiran Naqvi, Farhad Ravandi, Elias Jabbour, Ricardo De Lumpa, Hagop Kantarjian, Anjali Advani, Sudipto Mukherjee, Aaron Gerds, Hetty E. Carraway, Aziz Nazha, Hiroyuki Iwamura, Motohiko Murase, Linda Bavisotto, Michael Kurman, Gary Maier, Mary Johansen & Mikkael A. Sekeres
Pages: 1943-1953
Published online: 07 Apr 2020
AbstractforResults of a Phase 1/2a dose–escalation study of FF-10501-01, an IMPDH inhibitor, in patients with acute myeloid leukemia or myelodysplastic syndromes | Full Text | References | PDF (1.7 MB) | EPUB
  • 380 Views
  • 2 CrossRef citations
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Article
Comorbidities cluster with impaired functional capacities and depressive mood and predict adverse outcome in older patients with hematological malignancies
Laurenz Nagl, Karin Koinig, Florian Hofer & Reinhard Stauder
Pages: 1954-1964
Published online: 13 Apr 2020
AbstractforComorbidities cluster with impaired functional capacities and depressive mood and predict adverse outcome in older patients with hematological malignancies | Full Text | References | PDF (1.1 MB) | EPUB
  • 190 Views
  • 5 CrossRef citations
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Article
Safety of gemtuzumab ozogamicin as monotherapy or combination therapy in an expanded-access protocol for patients with relapsed or refractory acute myeloid leukemia
Eunice S. Wang, Richard Aplenc, Deborah Chirnomas, Michael Dugan, Salman Fazal, Swaminathan Iyer, Tara L. Lin, Sucha Nand, Kristen J. Pierce, Paul J. Shami, Jennifer J. Vermette & Camille N. Abboud
Pages: 1965-1973
Published online: 20 May 2020
AbstractforSafety of gemtuzumab ozogamicin as monotherapy or combination therapy in an expanded-access protocol for patients with relapsed or refractory acute myeloid leukemia | Full Text | References | PDF (784.7 KB) | EPUB | Supplemental
  • 3463 Views
  • 8 CrossRef citations
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Open Access
Article
Immunophenotypic modulation in pediatric B lymphoblastic leukemia and its implications in MRD detection
Ramalingam Thulasi Raman, Muthu Anurekha, Vaidhyanathan Lakshman, Ramakrishnan Balasubramaniam, Uppuluri Ramya & Raj Revathi
Pages: 1974-1980
Published online: 12 Apr 2020
AbstractforImmunophenotypic modulation in pediatric B lymphoblastic leukemia and its implications in MRD detection | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 289 Views
  • 1 CrossRef citations
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Article
Identification and validation of a prognostic 8-gene signature for acute myeloid leukemia
Yanli Zhang & Longyan Xiao
Pages: 1981-1988
Published online: 08 Apr 2020
AbstractforIdentification and validation of a prognostic 8-gene signature for acute myeloid leukemia | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 379 Views
  • 11 CrossRef citations
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Article
An effective early death scoring system for predicting early death risk in de novo acute promyelocytic leukemia
Ping Cai, Qian Wu, Yemin Wang, Xiaofei Yang, Xinyou Zhang & Suning Chen
Pages: 1989-1995
Published online: 31 Mar 2020
AbstractforAn effective early death scoring system for predicting early death risk in de novo acute promyelocytic leukemia | Full Text | References | PDF (952.7 KB) | EPUB | Supplemental
  • 163 Views
  • 9 CrossRef citations
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Article
Clinical outcomes with low dose anti-thymocyte globulin in patients undergoing matched unrelated donor allogeneic hematopoietic cell transplantation
Luke Mountjoy, Tania Jain, Katie L. Kunze, Nandita Khera, Lisa Z. Sproat, Woodburn Jennifer, Margaret McCallen, Jose F. Leis, Pierre Noel, James L. Slack & Jeanne Palmer
Pages: 1996-2002
Published online: 13 Apr 2020
AbstractforClinical outcomes with low dose anti-thymocyte globulin in patients undergoing matched unrelated donor allogeneic hematopoietic cell transplantation | Full Text | References | PDF (764.3 KB) | EPUB
  • 237 Views
  • 8 CrossRef citations
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Letters to the Editor

Letter
Characterizing the belinostat response in patients with relapsed or refractory angioimmunoblastic T-cell lymphoma
Ahmed Sawas, Helen Ma, Andrei Shustov, Pamela Hsu, Gajanan Bhat, Mark Acosta, Steven Horwitz & Owen A. O’Connor
Pages: 2003-2007
Published online: 26 Apr 2020
First Page PreviewforCharacterizing the belinostat response in patients with relapsed or refractory angioimmunoblastic T-cell lymphoma | Full Text | References | PDF (941.3 KB) | EPUB
  • 250 Views
  • 4 CrossRef citations
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Letter
Significance of isolated deletion (20q) in donor cells after allogeneic hematopoietic cell transplantation
Sunita Nathan, Sushma Bharadwaj, Kristy Luke, Laura Kalas, Deborah A. Katz, Mohammad Junaid Hussain, Ira Miller, Wei-Tong Hsu, Jamile Shammo, Parameswaran Venugopal & Celalettin Ustun
Pages: 2008-2011
Published online: 19 Apr 2020
First Page PreviewforSignificance of isolated deletion (20q) in donor cells after allogeneic hematopoietic cell transplantation | Full Text | References | PDF (599.7 KB) | EPUB
  • 164 Views
  • 1 CrossRef citations
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Letter
Impact of salvage treatment phase on inotuzumab ozogamicin treatment for relapsed/refractory acute lymphoblastic leukemia: an update from the INO-VATE final study database
Elias Jabbour, Matthias Stelljes, Anjali S. Advani, Daniel J. DeAngelo, Nicola Gökbuget, David I. Marks, Wendy Stock, Susan O’Brien, Ryan D. Cassaday, Tao Wang, Alexander Neuhof, Erik Vandendries & Hagop Kantarjian
Pages: 2012-2015
Published online: 07 May 2020
First Page PreviewforImpact of salvage treatment phase on inotuzumab ozogamicin treatment for relapsed/refractory acute lymphoblastic leukemia: an update from the INO-VATE final study database | Full Text | References | PDF (553.6 KB) | EPUB | Supplemental
  • 3726 Views
  • 10 CrossRef citations
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Open Access
Letter
Mantle cell lymphoma with dot-like nuclear staining for cyclin D1
Hoyuri Fuseya, Masahiro Yoshida, Rie Oyama, Naoko Tatsumi, Minako Tsutsumi, Yosuke Nakaya, Mirei Horiuchi, Takuro Yoshimura, Yoshiki Hayashi, Takafumi Nakao, Ryoko Sakagami, Takane Aoyama, Nozomi Nozuchi, Hiroko Fukushima, Takeshi Inoue & Takahisa Yamane
Pages: 2016-2019
Published online: 12 May 2020
First Page PreviewforMantle cell lymphoma with dot-like nuclear staining for cyclin D1 | Full Text | References | PDF (1.3 MB) | EPUB
  • 114 Views
  • 1 CrossRef citations
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Letter
The efficacy of venetoclax and hypomethylating agents in acute myeloid leukemia with extramedullary involvement
Salman Otoukesh, Jianying Zhang, Ryotaro Nakamura, Anthony S. Stein, Stephen J. Forman, Guido Marcucci, Vinod Pullarkat & Ibrahim Aldoss
Pages: 2020-2023
Published online: 19 Mar 2020
First Page PreviewforThe efficacy of venetoclax and hypomethylating agents in acute myeloid leukemia with extramedullary involvement | Full Text | References | PDF (359.9 KB) | EPUB
  • 681 Views
  • 14 CrossRef citations
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Letter
Detection of an IGH-BRAF fusion in a patient with BRAF Val600Glu negative hairy cell leukemia
Ella R. Thompson, Kenneth J.C. Lim, James A. Kuzich, Michelle McBean, David Westerman, Constantine S. Tam & Piers Blombery
Pages: 2024-2026
Published online: 22 Apr 2020
First Page PreviewforDetection of an IGH-BRAF fusion in a patient with BRAF Val600Glu negative hairy cell leukemia | Full Text | References | PDF (656.6 KB) | EPUB
  • 212 Views
  • 5 CrossRef citations
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Letter
How obesity and malnutrition interplay to affect mortality in critically ill patients with hematological malignancies: a retrospective cohort study
Andry Van de Louw, Xijun Zhu & David Frankenfield
Pages: 2027-2029
Published online: 04 May 2020
First Page PreviewforHow obesity and malnutrition interplay to affect mortality in critically ill patients with hematological malignancies: a retrospective cohort study | Full Text | References | PDF (306.7 KB) | EPUB
  • 113 Views
  • 1 CrossRef citations
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