553
Views
39
CrossRef citations to date
0
Altmetric
Research Article

Alendronate PLGA microspheres with high loading efficiency for dental applications

, , , &
Pages 525-538 | Received 29 Jan 2007, Accepted 08 May 2007, Published online: 08 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Sedat Ünal & Yeşim Aktaş. (2023) Bisphosphonate-loaded PLGA microspheres for bone regeneration in dental surgery: formulation, characterization, stability, and comprehensive release kinetic studies . International Journal of Polymeric Materials and Polymeric Biomaterials 72:1, pages 89-100.
Read now
Xiaoyuan Sha, Leung Chan, Xiaoyi Fan, Penghao Guo, Tianfeng Chen, Lian Liu & Jingxiang Zhong. (2022) Thermosensitive Tri-Block Polymer Nanoparticle-Hydrogel Composites as Payloads of Natamycin for Antifungal Therapy Against Fusarium Solani. International Journal of Nanomedicine 17, pages 1463-1478.
Read now
Soo-Ling Bee, Z. A. Abdul Hamid, M. Mariatti, B. H. Yahaya, Keemi Lim, Soo-Tueen Bee & Lee Tin Sin. (2018) Approaches to Improve Therapeutic Efficacy of Biodegradable PLA/PLGA Microspheres: A Review. Polymer Reviews 58:3, pages 495-536.
Read now
Elshaimaa G Sayed, Amal K Hussein, Khaled A Khaled & Osama AA Ahmed. (2015) Improved corneal bioavailability of ofloxacin: biodegradable microsphere-loaded ion-activated in situ gel delivery system. Drug Design, Development and Therapy 9, pages 1427-1435.
Read now
Umut Can Oz, Burcu Devrim, Asuman Bozkır & Kandemir Canefe. (2015) Development of reconstitutable suspensions containing diclofenac sodium-loaded microspheres for pediatric delivery. Journal of Microencapsulation 32:4, pages 317-328.
Read now
Deepak N Kapoor, Amit Bhatia, Ripandeep Kaur, Ruchi Sharma, Gurvinder Kaur & Sanju Dhawan. (2015) PLGA: a Unique Polymer for Drug Delivery. Therapeutic Delivery 6:1, pages 41-58.
Read now
Maha Nasr, Gehanne A. S. Awad, Samar Mansour, Abdelhamid Al Shamy & Nahed D. Mortada. (2013) Hydrophilic versus hydrophobic porogens for engineering of poly(lactide-co-glycolide) microparticles containing risedronate sodium. Pharmaceutical Development and Technology 18:5, pages 1078-1088.
Read now
Jian Zhou, TaoLin Fang, Jianchuan Wen, Zhengzhong Shao & Jian Dong. (2011) Silk coating on poly(ε-caprolactone) microspheres for the delayed release of vancomycin. Journal of Microencapsulation 28:2, pages 99-107.
Read now
Kai Su, Xuetao Shi, Rohan R Varshney & Dong-An Wang. (2011) Transplantable delivery systems for in situ controlled release of bisphosphonate in orthopedic therapy. Expert Opinion on Drug Delivery 8:1, pages 113-126.
Read now
Letícia Cruz, Evelise Assumpção, Sérgio Faloni Andrade, Daniela Joyce Conrado, Sílvia Stanisçuaski Guterres & Adriana Raffin Pohlmann. (2010) Microencapsulation of sodium alendronate reduces drug mucosal damage in rats. Drug Delivery 17:4, pages 231-237.
Read now
Yingjun Wang, Xuetao Shi, Li Ren, Yongchang Yao & Dong-An Wang. (2010) In Vitro Osteogenesis of Synovium Mesenchymal Cells Induced by Controlled Release of Alendronate and Dexamethasone from a Sintered Microspherical Scaffold. Journal of Biomaterials Science, Polymer Edition 21:8-9, pages 1227-1238.
Read now

Articles from other publishers (28)

Akanksha R. Singh & Rajani B. Athawale. (2023) Revolutionizing Drug Delivery: The Potential of PLGA Nanoparticles in Nanomedicine. Current Applied Polymer Science 6:2, pages 87-100.
Crossref
Debora Baptista Pereira, Beatriz Ferreira de Carvalho Patricio, Talita Goulart da Silva, Hellen Regina Oliveira de Almeida, Marcelo Henrique da Cunha Chaves, Michelle Alvares Sarcinelli, Helvécio Vinícius Antunes Rocha, Tiago dos Santos Mendonça, Tiago José Bandeira Sales & Roberta Helena Mendonça. (2023) Production of Polycaprolactone/Atorvastatin Films for Drug Delivery Application. Materials Research 26:suppl 1.
Crossref
N. Surya & S. Bhattacharyya. (2021) PLGA – THE SMART POLYMER FOR DRUG DELIVERY. Pharmacy & Pharmacology 9:5, pages 334-345.
Crossref
Zhengjie Lin, Danni Shen, Weixiao Zhou, Yufeng Zheng, Tiantian Kong, Xuanyong Liu, Shuilin Wu, Paul K. Chu, Ying Zhao, Jun Wu, Kenneth M.C. Cheung & Kelvin W.K. Yeung. (2021) Regulation of extracellular bioactive cations in bone tissue microenvironment induces favorable osteoimmune conditions to accelerate in situ bone regeneration. Bioactive Materials 6:8, pages 2315-2330.
Crossref
Patricia Garcia-Garcia, Ricardo Reyes, José Antonio Rodriguez, Tomas Martín, Carmen Evora, Patricia Díaz-Rodríguez & Araceli Delgado. (2021) The Bone Regeneration Capacity of BMP-2 + MMP-10 Loaded Scaffolds Depends on the Tissue Status. Pharmaceutics 13:7, pages 979.
Crossref
Łucja Rumian, Cornelia Wolf-Brandstetter, Sina Rößler, Katarzyna Reczyńska, Hanna Tiainen, Håvard J Haugen, Dieter Scharnweber & Elżbieta Pamuła. (2021) Sodium alendronate loaded poly( l -lactide- co -glycolide) microparticles immobilized on ceramic scaffolds for local treatment of bone defects . Regenerative Biomaterials 8:3.
Crossref
Rohith Jayaram, Patrick W. O'Donnell & David A. Puleo. (2021) Systems for local, sustained release of zoledronic acid as a potential treatment for metastatic bone disease. Materials Science and Engineering: C 118, pages 111395.
Crossref
Małgorzata Krok-Borkowicz, Katarzyna Reczyńska, Łucja Rumian, Elżbieta Menaszek, Maciej Orzelski, Piotr Malisz, Piotr Silmanowicz, Piotr Dobrzyński & Elżbieta Pamuła. (2020) Surface-Modified Poly(l-lactide-co-glycolide) Scaffolds for the Treatment of Osteochondral Critical Size Defects—In Vivo Studies on Rabbits. International Journal of Molecular Sciences 21:20, pages 7541.
Crossref
Raphael Mietzner, Christian Kade, Franziska Froemel, Diana Pauly, W. Daniel Stamer, Andreas Ohlmann, Joachim Wegener, Rudolf Fuchshofer & Miriam Breunig. (2020) Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy. Pharmaceutics 12:8, pages 706.
Crossref
Christina Koulouktsi, Stavroula Nanaki, Panagiotis Barmpalexis, Margaritis Kostoglou & Dimitrios Bikiaris. (2019) Preparation and characterization of Alendronate depot microspheres based on novel poly(-ε-caprolactone)/Vitamin E TPGS copolymers. International Journal of Pharmaceutics: X 1, pages 100014.
Crossref
Dagnija Loca, Anastasija Smirnova, Janis Locs, Arita Dubnika, Jana Vecstaudza, Liga Stipniece, Elina Makarova & Maija Dambrova. (2018) Development of local strontium ranelate delivery systems and long term in vitro drug release studies in osteogenic medium. Scientific Reports 8:1.
Crossref
Trinette Fernandes, Chintan Bhavsar, Sujata Sawarkar & Anisha D’souza. (2018) Current and novel approaches for control of dental biofilm. International Journal of Pharmaceutics 536:1, pages 199-210.
Crossref
Nicholas P. Murphy & Kyle J. Lampe. (2017) Fabricating PLGA microparticles with high loads of the small molecule antioxidant N‐acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress. Biotechnology and Bioengineering 115:1, pages 246-256.
Crossref
Dipendu Saha, Amanda Spurri, Jihua Chen & Dale K. Hensley. (2016) Controlled release of alendronate from nitrogen-doped mesoporous carbon. Microporous and Mesoporous Materials 229, pages 8-13.
Crossref
Farshad Ramazani, Weiluan Chen, Cornelis F. van Nostrum, Gert Storm, Fabian Kiessling, Twan Lammers, Wim E. Hennink & Robbert J. Kok. (2016) Strategies for encapsulation of small hydrophilic and amphiphilic drugs in PLGA microspheres: State-of-the-art and challenges. International Journal of Pharmaceutics 499:1-2, pages 358-367.
Crossref
Joonho Bae & Jin Woo Park. (2015) Preparation of an injectable depot system for long-term delivery of alendronate and evaluation of its anti-osteoporotic effect in an ovariectomized rat model. International Journal of Pharmaceutics 480:1-2, pages 37-47.
Crossref
Aline de Arce Velasquez, Luana Mota Ferreira, Mônica Fabiele Lorensi Stangarlin, Cristiane de Bona da Silva, Clarice Madalena Bueno Rolim & Letícia Cruz. (2014) Novel Pullulan–Eudragit® S100 blend microparticles for oral delivery of risedronate: Formulation, in vitro evaluation and tableting of blend microparticles. Materials Science and Engineering: C 38, pages 212-217.
Crossref
K. Miladi, S. Sfar, H. Fessi & A. Elaissari. (2013) Drug carriers in osteoporosis: Preparation, drug encapsulation and applications. International Journal of Pharmaceutics 445:1-2, pages 181-195.
Crossref
Sung Eun Kim, Dong Hun Suh, Young-Pil Yun, Jae Yong Lee, Kyeongsoon Park, Jun-Young Chung & Deok-Won Lee. (2012) Local delivery of alendronate eluting chitosan scaffold can effectively increase osteoblast functions and inhibit osteoclast differentiation. Journal of Materials Science: Materials in Medicine 23:11, pages 2739-2749.
Crossref
Efstathia Tsetsenekou, Triantafillos Papadopoulos, Demos Kalyvas, Nikos Papaioannou, Stefan Tangl & Georg Watzek. (2011) The influence of alendronate on osseointegration of nanotreated dental implants in New Zealand rabbits. Clinical Oral Implants Research 23:6, pages 659-666.
Crossref
Titash Mondal, M.C.Sunny, D.Khastgir, H.K.Varma & P. Ramesh. (2012) Poly (l-lactide-co-Є caprolactone) microspheres laden with bioactive glass-ceramic and alendronate sodium as bone regenerative scaffolds. Materials Science and Engineering: C 32:4, pages 697-706.
Crossref
Miguel Manzano, Gaetano Lamberti, Ivan Galdi & María Vallet-Regí. (2011) Anti-Osteoporotic Drug Release from Ordered Mesoporous Bioceramics: Experiments and Modeling. AAPS PharmSciTech 12:4, pages 1193-1199.
Crossref
Dario Puppi, Anna Maria Piras, Federica Chiellini, Emo Chiellini, Albino Martins, Isabel B. Leonor, Nuno Neves & Rui Reis. (2011) Optimized electro- and wet-spinning techniques for the production of polymeric fibrous scaffolds loaded with bisphosphonate and hydroxyapatite. Journal of Tissue Engineering and Regenerative Medicine 5:4, pages 253-263.
Crossref
Maha Nasr, Gehanne A.S. Awad, Samar Mansour, Abdelhamid Al Shamy & Nahed D. Mortada. (2011) A Reliable Predictive Factorial Model for Entrapment Optimization of a Sodium Bisphosphonate into Biodegradable Microspheres. Journal of Pharmaceutical Sciences 100:2, pages 612-621.
Crossref
Montserrat Colilla, Isabel Izquierdo-Barba & María Vallet-Regí. (2010) Phosphorus-containing SBA-15 materials as bisphosphonate carriers for osteoporosis treatment. Microporous and Mesoporous Materials 135:1-3, pages 51-59.
Crossref
Hagar Ibrahim Labouta & Labiba K. El-Khordagui. (2010) Polymethacrylate Microparticles Gel for Topical Drug Delivery. Pharmaceutical Research 27:10, pages 2106-2118.
Crossref
Xuetao Shi, Yingjun Wang, Rohan R. Varshney, Li Ren, Feng Zhang & Dong-An Wang. (2009) In-vitro osteogenesis of synovium stem cells induced by controlled release of bisphosphate additives from microspherical mesoporous silica composite. Biomaterials 30:23-24, pages 3996-4005.
Crossref
Xuetao Shi, Yingjun Wang, Li Ren, Yihong Gong & Dong-An Wang. (2008) Enhancing Alendronate Release from a Novel PLGA/Hydroxyapatite Microspheric System for Bone Repairing Applications. Pharmaceutical Research 26:2, pages 422-430.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.