5,813
Views
402
CrossRef citations to date
0
Altmetric
Review Article

Non-alcoholic fatty liver disease (NAFLD) – pathogenesis, classification, and effect on drug metabolizing enzymes and transporters

ORCID Icon & ORCID Icon
Pages 197-211 | Received 26 Dec 2016, Accepted 30 Jan 2017, Published online: 17 Mar 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (25)

Zakiah N. Almohawes, Attalla El-Kott, Kareem Morsy, Ali A. Shati, Ayman E. El-Kenawy, Heba S. Khalifa, Fahmy G. Elsaid, Abd-El-Karim M. Abd-Lateif, Ahmed Abu-Zaiton, Eman R. Ebealy, Mohamed M. Abdel-Daim, Reham A. Ghanem & Eman M. Abd-Ella. (2024) Salidroside inhibits insulin resistance and hepatic steatosis by downregulating miR-21 and subsequent activation of AMPK and upregulation of PPARα in the liver and muscles of high fat diet-fed rats. Archives of Physiology and Biochemistry 130:3, pages 257-274.
Read now
Ning Zhang, Tong Liu, Jianan Wang, Yingying Xiao, Ying Zhang, Jun Dai, Zhihong Ma & Donglai Ma. (2023) Si-Ni-San Reduces Hepatic Lipid Deposition in Rats with Metabolic Associated Fatty Liver Disease by AMPK/SIRT1 Pathway. Drug Design, Development and Therapy 17, pages 3047-3060.
Read now
Nour Al-Kazimi, Yazun Jarrar, Ghasaq Abdul-Wahab, Ahmad R. Alsayed, Abdalla Madani, Dina Abulebdah, Rami Salem Musleh, Qais Jarrar, Hamzeh J Al-Ameer, Wajdy Al-Awaida & Eman Abdullah. (2023) Effects of intermittent fasting on the histology and mRNA expression of major drug-metabolizing cyp450s in the liver of diabetic mice. Libyan Journal of Medicine 18:1.
Read now
Samuele Laudani & Giuseppe Grosso. (2023) Gut-liver axis: may prebiotics play a role?. International Journal of Food Sciences and Nutrition 74:7, pages 719-720.
Read now
Paresh P. Chothe, Pallabi Mitra, Masanori Nakakariya, Diane Ramsden, Charles J. Rotter, Philip Sandoval & Kimio Tohyama. (2023) Drug transporters in drug disposition – the year 2022 in review. Drug Metabolism Reviews 55:4, pages 343-370.
Read now
Yan Zhu, Li Chen, Yuqi He, Lin Qin, Daopeng Tan, Zhaojun Bai, Yu Song & Yu-He Wang. (2023) The alteration of drug metabolism enzymes and pharmacokinetic parameters in nonalcoholic fatty liver disease: current animal models and clinical practice. Drug Metabolism Reviews 55:3, pages 163-180.
Read now
Tingting Qin, Xiuying Chen, Jiahui Meng, Qianqian Guo, Shan Xu, Shanshan Hou, Ziqiao Yuan & Wenzhou Zhang. (2023) The role of curcumin in the liver-gut system diseases: from mechanisms to clinical therapeutic perspective. Critical Reviews in Food Science and Nutrition 0:0, pages 1-30.
Read now
Yang Shen, Xianan Li, Shichao Xiong, Shaoying Hou, Lijia Zhang, Li Wang, Xuezheng Dai & Yan Zhao. (2023) Untargeted metabonomic analysis of non-alcoholic fatty liver disease with iron overload in rats via UPLC/MS. Free Radical Research 57:3, pages 195-207.
Read now
Zheng Xu, Fan-Wei Wu, Xuan Niu, Xiao-Peng Lu, Yan-Rong Li, Shu-Ting Zhang, Jun-Zhao Ou & Xue-Mei Wang. (2022) Integrated strategy of RNA-sequencing and network pharmacology for exploring the protective mechanism of Shen-Shi-Jiang-Zhuo formula in rat with non-alcoholic fatty liver disease. Pharmaceutical Biology 60:1, pages 1819-1838.
Read now
Ruifeng Liang, Wenjing Ge, Bingjie Li, Weifeng Cui, Xiaofan Ma, Yuying Pan & Gengsheng Li. (2022) Evodiamine decreased the systemic exposure of pravastatin in non-alcoholic steatohepatitis rats due to the up-regulation of hepatic OATPs. Pharmaceutical Biology 60:1, pages 359-373.
Read now
Yunxiao Gao, Rongrong Tian, Haiyue Liu, Huimin Xue, Ruizhe Zhang, Suping Han, Lin Ji, Weidong Huang, Jicheng Zhan & Yilin You. (2022) Research progress on intervention effect and mechanism of protocatechuic acid on nonalcoholic fatty liver disease. Critical Reviews in Food Science and Nutrition 62:32, pages 9053-9075.
Read now
Tahmine Tavakoli, Asghar Zarban, Reyhaneh Hooshyar, Fatemeh Salmani & Hamidreza Tajik. (2022) Improvement of thiol groups and total antioxidant capacity in patients with non-alcoholic fatty liver after treatment with pioglitazone. Archives of Physiology and Biochemistry 128:6, pages 1591-1595.
Read now
Shuai Chen, Xiurong Cai, Yu Liu, Yu Shen, Adrien Guillot, Frank Tacke, Liming Tang & Hanyang Liu. (2022) The macrophage-associated microRNA-4715-3p / Gasdermin D axis potentially indicates fibrosis progression in nonalcoholic fatty liver disease: evidence from transcriptome and biological data. Bioengineered 13:5, pages 11740-11751.
Read now
Yu Xia, Yanxia Zhang & Huiyun Wang. (2021) Upregulated lncRNA HCG18 in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance. Diabetes, Metabolic Syndrome and Obesity 14, pages 4747-4756.
Read now
Xiaoyu Wang, Guangbing Li, Changfa Guo, Jiayao Zhang, Junjie Kong, Jingyi He, Feiyu Li, Yong Liu, Yang Yang, Ziwen Lu & Jun Liu. (2021) Ethyl 2-[2,3,4-Trimethoxy-6-(1-Octanoyl)Phenyl] Acetate (TMPA) Ameliorates Lipid Accumulation by Disturbing the Combination of LKB1 with Nur77 and Activating the AMPK Pathway in HepG2 Cells and Mice Primary Hepatocytes . Diabetes, Metabolic Syndrome and Obesity 14, pages 4165-4177.
Read now
Xiao-yu Liang, Fen-Fang Hong & Shu-Long Yang. (2021) Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease. Diabetes, Metabolic Syndrome and Obesity 14, pages 1871-1883.
Read now
Ling Zhao, Fang Chen, Yuanli Zhang, Ling Yue, Hongrui Guo, Gang Ye, Fei Shi, Cheng Lv, Bo Jing, Huaqiao Tang, Zhongqiong Yin, Hualin Fu, Jvchun Lin, Yinglun Li & Xun Wang. (2020) Involvement of P450s and nuclear receptors in the hepatoprotective effect of quercetin on liver injury by bacterial lipopolysaccharide. Immunopharmacology and Immunotoxicology 42:3, pages 211-220.
Read now
Wanwei Yang, Cuihua Jiang, Zhiguo Wang, Jian Zhang, Xiaodong Mao, Guofang Chen, Xiaoming Yao & Chao Liu. (2020) Cyclocarya paliurus extract attenuates hepatic lipid deposition in HepG2 cells by the lipophagy pathway. Pharmaceutical Biology 58:1, pages 838-844.
Read now
Yu Ji, Kenneth Elkin, James Yip, Longfei Guan, Wei Han & Yuchuan Ding. (2019) From circadian clocks to non-alcoholic fatty liver disease. Expert Review of Gastroenterology & Hepatology 13:11, pages 1107-1112.
Read now
Yazun Bashir Jarrar, Luay Al-Essa, Abdulhasib Kilani, Mariam Hasan & Walid Al-Qerem. (2018) Alterations in the gene expression of drug and arachidonic acid-metabolizing Cyp450 in the livers of controlled and uncontrolled insulin-dependent diabetic mice. Diabetes, Metabolic Syndrome and Obesity 11, pages 483-492.
Read now
Shu Dai, Ke Fu, Yanfang Liu, Yuxin Yao, Fang Zhang, Rui Wu, Yiling Guo, Chenghao Yao & Yunxia Li. Vitexin: A Dietary Flavonoid with Potential Protective Effects Against Liver Diseases. Food Reviews International 0:0, pages 1-37.
Read now

Articles from other publishers (377)

Karli R. LeFort, Wiramon Rungratanawanich & Byoung-Joon Song. (2024) Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications, inflammation, and intestinal barrier dysfunction. Cellular and Molecular Life Sciences 81:1.
Crossref
Sharareh Kamfar, Bardia Danaei, Samane Rahimi & Vahide Zeinali. (2024) Novel blood and tissue-based mitochondrial D-loop mutations detected in an Iranian NAFLD patient cohort. Mitochondrion 77, pages 101888.
Crossref
Ali Mahmoudi, Amin Jalili, Alexandra E. Butler, Seyed H. Aghaee-Bakhtiari, Tannaz Jamialahmadi & Amirhossein Sahebkar. (2024) Exploration of the Key Genes Involved in Non-alcoholic Fatty Liver Disease and Possible MicroRNA Therapeutic Targets. Journal of Clinical and Experimental Hepatology 14:4, pages 101365.
Crossref
Xuan Leng, Wan-Zhe Liao & Fen-Ping Zheng. (2024) Gastroesophageal reflux disease and non-alcoholic fatty liver disease: a two-sample Mendelian randomization combined with meta-analysis. Scientific Reports 14:1.
Crossref
Rui Li, Ming Li, Alyce D. Fly, Aurelian Bidulescu & Juhua Luo. (2024) Vegetarian diets and risk of nonalcoholic fatty liver disease: An observational study of National Health and Nutrition Examination Survey 2005–2018 using propensity score methods. Journal of Human Nutrition and Dietetics 37:3, pages 643-654.
Crossref
Lixuan Fang, Jine Li, Haixia Zeng & Jianping Liu. (2024) Effects of GLP-1 receptor agonists on the degree of liver fibrosis and CRP in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: A systematic review and meta-analysis. Primary Care Diabetes 18:3, pages 268-276.
Crossref
Wanrun Xie, Zhenzhen Hong, Bo Li, Baoliang Huang, Shaobin Dong, Yuqi Cai, Lingyan Ruan, Qianhui Xu, Lunpan Mou & Yi Zhang. (2024) Influence of glucagon-like peptide-1 receptor agonists on fat accumulation in patients with diabetes mellitus and non-alcoholic fatty liver disease or obesity: A systematic review and meta-analysis of randomized control trials. Journal of Diabetes and its Complications 38:6, pages 108743.
Crossref
Xiangning Duan, Haoliang Hu, Lingzhi Wang & Linxi Chen. (2024) Aldehyde dehydrogenase 1 family: A potential molecule target for diseases. Cell Biology International.
Crossref
Yuwen Zhang, Peizhan Chen & Xuqian Fang. (2024) Proteomic and metabolomic analysis of GH deficiency-induced NAFLD in hypopituitarism: insights into oxidative stress. Frontiers in Endocrinology 15.
Crossref
Chao-Jie Wang, Yu-Xia HuTu-Ya BaiJun LiHan WangXiao-Li LvMeng-Di ZhangFu-Hou Chang. (2024) Identification of disease-specific genes related to immune infiltration in nonalcoholic steatohepatitis using machine learning algorithms. Medicine 103:20, pages e38001.
Crossref
Teresa Sierra & Brahim Achour. (2024) In Vitro to In Vivo Scalars for Drug Clearance in Nonalcoholic Fatty Liver and Steatohepatitis. Drug Metabolism and Disposition 52:5, pages 390-398.
Crossref
Xiong Pei, Wei Jiang, Lianchi Li, Qingmin Zeng, Chang‐Hai Liu, Ming Wang, Enqiang Chen, Taoyou Zhou, Hong Tang & Dongbo Wu. (2024) Mendelian‐randomization study revealed causal relationship between nonalcoholic fatty liver disease and osteoporosis/fractures. Journal of Gastroenterology and Hepatology 39:5, pages 847-857.
Crossref
Ahmed Ragab, Ali M Abdel Fattah, Ahmed Reda Sayed, Sameh Fayek GamalEl Din, Shrouk Matrawy Mahmoud Hassan, Aya Yaseen Mohamed Mohamed & Mostafa Ahmed Hamed. (2024) Correlation between Serum Levels of Nitric Oxide and Adropin and Erectile Dysfunction in Males with Nonalcoholic Fatty Liver Disease: An Observational Study. Reproductive Sciences.
Crossref
Dongliang Chen, Yuanfei Wang, Jianmei Yang, Wanyi Ou, Guiru Lin, Ze Zeng, Xiaomin Lu, Zumin Chen, Lili Zou, Yaling Tian, Aiping Wu, Shelley E. Keating, Qinhe Yang, Chenli Lin & Yinji Liang. (2024) Shenling Baizhu San ameliorates non-alcoholic fatty liver disease in mice by modulating gut microbiota and metabolites. Frontiers in Pharmacology 15.
Crossref
Muhammed Mubarak. (2024) Changes in the terminology and diagnostic criteria of non-alcoholic fatty liver disease: Implications and opportunities. World Journal of Gastrointestinal Pathophysiology 15:1.
Crossref
Yansong Fu, Zhipeng Wang & Hong Qin. (2024) Examining the Pathogenesis of MAFLD and the Medicinal Properties of Natural Products from a Metabolic Perspective. Metabolites 14:4, pages 218.
Crossref
Juanjiang Wu, Huaxue Huang, Limin Gong, Xing Tian, Zhi Peng, Yizhun Zhu & Wei Wang. (2024) A Flavonoid Glycoside Compound from Siraitia grosvenorii with Anti-Inflammatory and Hepatoprotective Effects In Vitro. Biomolecules 14:4, pages 450.
Crossref
Mily MandalSambuddha Ghosh, Satarupa RoySayani MandalAnindya Dasgupta. (2024) Association of Diabetic Retinopathy with Midlife Hepatic Steatosis Diagnosed by Elastography and Hepatic Steatosis Index in Type 2 Diabetes in an Indian Population. Metabolic Syndrome and Related Disorders 22:3, pages 214-221.
Crossref
Mengjuan Zhang, Haifeng Zhang, Lu Jia, Yi Zhang, Runwen Qin, Shihua Xu & Yingwu Mei. (2024) Health benefits and mechanisms of theobromine. Journal of Functional Foods 115, pages 106126.
Crossref
Xin Su, Qinchen Xu, Zigan Li, Yidan Ren, Qinlian Jiao, Lina Wang & Yunshan Wang. (2024) Role of the angiopoietin-like protein family in the progression of NAFLD. Heliyon 10:7, pages e27739.
Crossref
Olivier Govaere, Simon J. Cockell, Michalina Zatorska, Kristy Wonders, Dina Tiniakos, Andrew M. Frey, Pawel Palmowksi, Ruth Walker, Andrew Porter, Matthias Trost, Quentin M. Anstee & Ann K. Daly. (2024) Pharmacogene expression during progression of metabolic dysfunction-associated steatotic liver disease: Studies on mRNA and protein levels and their relevance to drug treatment. Biochemical Pharmacology, pages 116249.
Crossref
Bo Guo, Shengzhe Yan, Lei Zhai & Yanzhen Cheng. (2024) LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA. Cytotechnology 76:2, pages 259-269.
Crossref
Ali Mahmoudi, Mohammad Mahdi Hajihasani, Muhammed Majeed, Tannaz Jamialahmadi & Amirhossein Sahebkar. (2024) Effect of Calebin-A on Critical Genes Related to NAFLD: A Protein-Protein Interaction Network and Molecular Docking Study. Current Genomics 25:2, pages 120-139.
Crossref
Mengxiao Zhang, Yu Chen, Shuoshuo Sun, Shaohong Zhang, Li Yuan, Yijiao Xu, Xingjia Li, Guofang Chen, Xiao Wei & Chao Liu. (2024) Ketogenic diet alleviates β-cell dedifferentiation but aggravates hepatic lipid accumulation in db/db mice. Nutrition 119, pages 112284.
Crossref
Zedong Xiang, Huida Guan, Xiang Zhao, Qi Xie, Zhejun Xie, Fujie Cai, Rui Dang, Manlin Li & Changhong Wang. (2024) Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions. Food Research International 180, pages 114068.
Crossref
Jie Zhao, Baozhen Li, Kai ZhangZhiyong Zhu. (2024) The effect and safety of obeticholic acid for patients with nonalcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials. Medicine 103:7, pages e37271.
Crossref
Xiang Zhang, Zhenghao Jiang, Xiaoliang JinQiujun Zhou. (2024) Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review. Medicine 103:5, pages e37052.
Crossref
Omar Elhelw, Sharanniyan Ragavan, Waseem Majeed, Bilal Alkhaffaf, Noor Mohammed, Siba Senapati, Basil J. Ammori, James Andrew Robinson & Akheel A. Syed. (2024) The impact of bariatric surgery on liver enzymes in people with obesity: A 5-year observational study. The Surgeon 22:1, pages e26-e33.
Crossref
Fernando Moreto, Jéssica Leite Garcia, Ana Lúcia dos Anjos Ferreira, Silvia Radrezza, Mariane Róvero Costa, Guilherme Ribeiro Romualdo, Nubia Alves Grandini, Giancarlo Aldini, Camila Renata Correa & Alfonsina D'Amato. (2024) Quantitative proteomics study of carnosine effect in an animal model of Western diet‐induced nonalcoholic fatty liver disease. Journal of Biochemical and Molecular Toxicology 38:2.
Crossref
Lucia Longhitano, Alfio Distefano, Nicolò Musso, Paolo Bonacci, Laura Orlando, Sebastiano Giallongo, Daniele Tibullo, Simona Denaro, Giuseppe Lazzarino, Jessica Ferrigno, Anna Nicolosi, Amer M. Alanazi, Federico Salomone, Emanuela Tropea, Ignazio Alberto Barbagallo, Vincenzo Bramanti, Giovanni Li Volti, Giacomo Lazzarino, Daniele Torella & Angela Maria Amorini. (2024) (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease. Journal of Translational Medicine 22:1.
Crossref
Xue Wang, Yanqiu Chen, Heyu Meng & Fanbo Meng. (2024) SREBPs as the potential target for solving the polypharmacy dilemma. Frontiers in Physiology 14.
Crossref
Fengming Wu, Siyuan Bu & Hongmei Wang. (2024) Role of TRP Channels in Metabolism-Related Diseases. International Journal of Molecular Sciences 25:2, pages 692.
Crossref
Tong Nie, Xin Wang, Aqun Li, Anshan Shan & Jun Ma. (2024) The promotion of fatty acid β-oxidation by hesperidin via activating SIRT1/PGC1α to improve NAFLD induced by a high-fat diet . Food & Function 15:1, pages 372-386.
Crossref
Qi ZhangYutong ChenJingqi LiHaishan XiaYongbin TongYuyu Liu. (2024) Recent Advances in Hepatic Metabolic Regulation by the Nuclear Factor Rev-erbɑ. Current Drug Metabolism 25:1, pages 2-12.
Crossref
Haoran Jiang & Linquan Zang. (2024) GLP-1/GLP-1RAs: New Options for the Drug Treatment of NAFLD. Current Pharmaceutical Design 30:2, pages 100-114.
Crossref
Xiankuan Li, Weisan Chen, Jiali Ren, Xinchen Gao, Ying Zhao, Tianbao Song, Kun Fu, Yanchao Zheng & Jinlong Yang. (2024) Effects of curcumin on non-alcoholic fatty liver disease: A scientific metrogy study. Phytomedicine 123, pages 155241.
Crossref
Wenyu Cui, Ben Xu, Fuchun Chen, Weijun Shen, Fachun Wan & Anwei Cheng. (2024) Effects of grape peel phenolics on lipid accumulation in sodium palmitate-treated HepG2 cells. Journal of Functional Foods 112, pages 105923.
Crossref
Can Jin, Tingting Zhou, Zhihao Duan, Ying Deng, Xiaoli Zhang, Changyi Xiao, Jiangang He, Gongwei He, You Zhou & Shigang Li. (2024) Effect of chin brick tea [Camellia sinensis (L.) Kuntze] on lipid metabolism and inflammation by modulating intestinal flora and bile acids in mice with non-alcoholic fatty liver disease. Journal of Ethnopharmacology 318, pages 116950.
Crossref
Gary C. Kanel. 2024. Atlas of Liver Pathology. Atlas of Liver Pathology 101 132.e4 .
Hang Zhao & Hongyang Tian. (2023) Icariin alleviates high‐fat diet‐induced nonalcoholic fatty liver disease via up‐regulating miR‐206 to mediate NF‐κB and MAPK pathways. Journal of Biochemical and Molecular Toxicology 38:1.
Crossref
О. Й. Комариця. (2023) СТЕАТОЗ ПЕЧІНКИ У ПАЦІЄНТІВ ЗІ СТАБІЛЬНОЮ СТЕНОКАРДІЄЮ. Здобутки клінічної і експериментальної медицини:4, pages 88-90.
Crossref
Changhao Li, Nana Wang, Yuting Li, Hui Yang, Jiafu Li & Zengli Zhang. (2023) Environmental Cadmium Exposure Exacerbated Bone Loss in NAFLD Mice. Biological Trace Element Research.
Crossref
Yunhua Qianshi, Lei Huang, Jun Jin, Yanmei Li, Yanan Li, Xiaojiang Hao & Chunmao Yuan. (2023) Three rare nor-sesquiterpenoids with lipid-lowering activity from Belamcanda chinensis . Organic & Biomolecular Chemistry 21:48, pages 9640-9646.
Crossref
Marta Guariglia, Francesca Saba, Chiara Rosso & Elisabetta Bugianesi. (2023) Molecular Mechanisms of Curcumin in the Pathogenesis of Metabolic Dysfunction Associated Steatotic Liver Disease. Nutrients 15:24, pages 5053.
Crossref
Prerna Sahu, Pratyaksh Chhabra & Ashok M Mehendale. (2023) A Comprehensive Review on Non-Alcoholic Fatty Liver Disease. Cureus.
Crossref
Hu Yang, Tengfei Zhang, Wen Song, Zhaohong Peng, Yu Zhu, Yong Huang, Xiude Li, Zhuang Zhang, Min Tang & Wanshui Yang. (2023) Dietary inflammatory potential is associated with higher odds of hepatic steatosis in US adults: a cross-sectional study. Public Health Nutrition 26:12, pages 2936-2944.
Crossref
Yinzhao Jia, Hao Pan, Jing Liu, Tiezeng Huang, Ke Han, Qiaojuan Mei, Ling Zeng, Jinzhao Zhou & Yong Zhang. (2023) MiR ‐484 promotes nonalcoholic fatty liver disease progression in mice via downregulation of Sorbs2 . Obesity 31:12, pages 2972-2985.
Crossref
Narges Milkarizi, Hanieh Barghchi, Saba Belyani, Farnood Rajabzadeh, Andisheh Norouzian Ostad, Seyede Yegane Ghelichi Kheyrabadi, Maryam Razavidarmian, Ladan Goshayeshi, Farkhondeh Farkhondeh, Seyyed Reza Sobhani, Mohsen Nematy & Vahid Reza Askari. (2023) Effect of Complementary Therapy with Hydro-Ethanolic Extract of Aerial Parts of Portulaca oleracea on Clinical and Paraclinical Findings in Patients with Non-alcoholic Fatty Liver Disease: A Randomized Clinical Trial Protocol. Hepatitis Monthly In Press:In Press.
Crossref
Shota Suzuki, Ryo Higashide, Fumiko Tsubata, Masae Sakamoto & Koji Shimabukuro. (2023) Acute Fatty Liver of Pregnancy Complicated With Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion: A Case Report. Cureus.
Crossref
Guang-Hui Deng, Chao-Feng Wu, Yun-Jia Li, Hao Shi, Wei-Chao Zhong, Mu-Keng Hong, Jun-Jie Li, Jia-Min Zhao, Chang Liu, Meng-Chen Qin, Zhi-Yun Zeng, Wei-Min Zhang, Ken Kin Lam Yung, Zhi-Ping Lv & Lei Gao. (2023) Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease. Military Medical Research 10:1.
Crossref
Jie Tang, Lixiang Wang, Mengge Shi, Shuaixia Feng, Tong Zhang & Han Han. (2023) Study on the mechanism of Shuganzhi Tablet against nonalcoholic fatty liver disease and lipid regulation effects of its main substances in vitro. Journal of Ethnopharmacology 316, pages 116780.
Crossref
Wenjie Wu, Chunke Zhang, Xiaotian Ma, Rui Guo, Jianjun Yan, Yiqin Wang, Haixia Yan & Yeqing Zhang. (2023) An early screening model of pulse detection technology for hepatic steatosis. Intelligent Medicine 3:4, pages 280-286.
Crossref
Yu Li, Xifeng Liang, Yaning Lyu, Kexue Wang, Linjing Han, Yuhan Wang, Jing Sun & Cheng Chi. (2023) Association between the gut microbiota and nonalcoholic fatty liver disease: A two-sample Mendelian randomization study. Digestive and Liver Disease 55:11, pages 1464-1471.
Crossref
Yongli Han, Lingling Luo, Hongli Li, Lijun Zhang, Yingxuan Yan, Minglv Fang, Jing Yu, Xiaoyan Gao, Ying Liu, Cheng Huang & Shengjie Fan. (2023) Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti‐inflammation capacity. BioFactors 49:6, pages 1189-1204.
Crossref
Kathrin Golla, Andreas Benesic, Hanna Mannell, Tobias Dreischulte, Eva Grill & Dorothea Strobach. (2023) Hepatic Impairment as a Risk Factor for Drug Safety: Suitability and Comparison of Four Liver Scores as Screening Tools. Journal of Clinical Medicine 12:21, pages 6814.
Crossref
Kaiyang Ma, Weixi Sheng, Xinxin Song, Jiangfeng Song, Ying Li, Wuyang Huang & Yuanfa Liu. (2023) Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway. Molecules 28:21, pages 7257.
Crossref
Iskandar Azmy Harahap, Maciej Kuligowski, Marcin Schmidt, Paweł Kurzawa & Joanna Suliburska. (2023) Influence of Isoflavones and Probiotics on Magnesium Status in Healthy Female Rats. Foods 12:21, pages 3908.
Crossref
Rong YangJian-Gao Fan. (2023) Non-alcoholic fatty liver disease and risk of cardiovascular diseases: clinical association, pathophysiological mechanisms, and management. Cardiology Plus 8:4, pages 217-226.
Crossref
Lu Liu, Sen Sun & Xiaohua Li. (2023) A network pharmacology-based approach to explore the effect of dihydromyricetin on non-alcoholic fatty liver rats via regulating PPARG and CASP3. Molecular and Cellular Probes 71, pages 101926.
Crossref
Victória Silva, Hector Oreliana Fernandes Faria, Celso Pereira Batista Sousa-Filho, José Fernando Rinaldi de Alvarenga, Jarlei Fiamoncini & Rosemari Otton. (2023) Thermoneutrality or standard temperature: is there an ideal housing temperature to study the antisteatotic effects of green tea in obese mice?. The Journal of Nutritional Biochemistry 120, pages 109411.
Crossref
Woonghee Kim, Mengzhen Li, Han Jin, Hong Yang, Hasan Türkez, Mathias Uhlén, Cheng Zhang & Adil Mardinoglu. (2023) Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients. iScience 26:10, pages 107727.
Crossref
Hui You, Xin Wen, Xingchun Wang, Cuiling Zhu, Haibing Chen, Le Bu, Jun Zhang & Shen Qu. (2023) Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1. Free Radical Biology and Medicine 207, pages 260-271.
Crossref
Ana L. Alcantara-Diaz, Jaime F. Ruiz-Fernandez, Jorge L. Salazar-Alarcon, Gustavo Salinas-Sedo & Carlos J. Toro-Huamanchumo. (2023) Diagnostic Performance of 2D Shear Wave (2D-SWE) for Liver Fibrosis in Adults Undergoing Bariatric Surgery. Obesity Surgery 33:10, pages 3120-3126.
Crossref
Ji-xi Wan, Yu-qi Wang, Si-na Lan, Liu Chen, Ming-qian Feng & Xin Chen. (2023) Research Progress in Function and Regulation of E3 Ubiquitin Ligase SMURF1. Current Medical Science 43:5, pages 855-868.
Crossref
Majid Mufaqam Syed-Abdul. (2023) Expanding Pharmacists’ Role in the Management of Non-Alcoholic Fatty Liver Disease. Pharmacy 11:5, pages 151.
Crossref
Dae Eon Kang & Si Nae Oh. (2023) Association between Alcohol Consumption and Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Alcohol Flushing Response in Men: The Korea National Health and Nutrition Examination Survey 2019–2021. Nutrients 15:18, pages 3901.
Crossref
M. Estefanía González-Alvarez & Aileen F. Keating. (2023) Hepatic and ovarian effects of perfluorooctanoic acid exposure differ in lean and obese adult female mice. Toxicology and Applied Pharmacology 474, pages 116614.
Crossref
Léonie Dopavogui, Marion Régnier, Arnaud Polizzi, Quentin Ponchon, Sarra Smati, Wendy Klement, Frédéric Lasserre, Céline Lukowicz, Yannick Lippi, Anne Fougerat, Justine Bertrand-Michel, Claire Naylies, Cécile Canlet, Laurent Debrauwer, Elodie Rousseau-Bacquié, Laurence Gamet-Payrastre, Charlène Dauriat, Josefina Casas, Siska Croubels, Siegrid De Baere, Hester M. Burger, Benoit Chassaing, Sandrine Ellero-Simatos, Hervé Guillou, Isabelle P. Oswald & Nicolas Loiseau. (2023) Obesity promotes fumonisin B1 hepatotoxicity. Science of The Total Environment 891, pages 164436.
Crossref
Steven H. Liu, Patricia Cerri-Droz, Kenny Ling, Rachel A. Loyst, Stephen Bowen, Brandon Lung, David E. Komatsu & Edward D. Wang. (2023) Increased preoperative aspartate aminotransferase-to-platelet ratio index predicts complications following total shoulder arthroplasty. JSES International 7:5, pages 855-860.
Crossref
Cen Xiang, Xiaoxuan Chen, Jiaping Yao, Na Yang, Jiajia Yu, Quanyuan Qiu, Shouqing Zhang, Xiangsun Kong, Lianbo Zhao, Zhen-Chuan Fan, Peng Yu & Yu-ou Teng. (2023) Design, synthesis and anti-NASH effect evaluation of novel GFT505 derivatives in vitro and in vivo. European Journal of Medicinal Chemistry 257, pages 115510.
Crossref
Jing Sun, Xiuli Jin, Xinhe Zhang & Birong Zhang. (2023) HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression. Cellular Signalling 109, pages 110741.
Crossref
Kexin Zhang, Jingwen Zhang, Chengxia Kan, Hongzhan Tian, Yanhui Ma, Na Huang, Fang Han, Ningning Hou & Xiaodong Sun. (2023) Role of dysfunctional peri-organ adipose tissue in metabolic disease. Biochimie 212, pages 12-20.
Crossref
Zhenfei Chi, Yun Teng, Yuting Liu, Lu Gao, Junhan Yang & Zhe Zhang. (2023) Association between klotho and non-alcoholic fatty liver disease and liver fibrosis based on the NHANES 2007–2016. Annals of Hepatology 28:5, pages 101125.
Crossref
Yiming Cao, Xiaoxue Fang, Mingyang Sun, Yegang Zhang, Mengyao Shan, Xintian Lan, Difu Zhu & Haoming Luo. (2023) Preventive and therapeutic effects of natural products and herbal extracts on nonalcoholic fatty liver disease / nonalcoholic steatohepatitis . Phytotherapy Research 37:9, pages 3867-3897.
Crossref
Jiajun Qiu, Maobin Kuang, Ruijuan Yang, Changhui Yu, Shiming He, Guotai Sheng & Yang Zou. (2023) The newly proposed alanine aminotransferase to high-density lipoprotein cholesterol ratio has shown effectiveness in identifying non-alcoholic fatty liver disease. Frontiers in Endocrinology 14.
Crossref
Yunseong Nam, Myungsuk Kim, Saruul Erdenebileg, Kwang Hyun Cha, Da Hye Ryu, Ho Youn Kim, Su Hyeon Lee, Je Hyeong Jung & Chu Won Nho. (2023) Sanguisorba officinalis L. Ameliorates Hepatic Steatosis and Fibrosis by Modulating Oxidative Stress, Fatty Acid Oxidation, and Gut Microbiota in CDAHFD-Induced Mice. Nutrients 15:17, pages 3779.
Crossref
Bao-Fei Yan, Lan-Fen Pan, Yi-Fang Quan, Qian Sha, Jing-Zheng Zhang, Yi-Feng Zhang, Li-Bing Zhou, Xi-Long Qian, Xiao-Mei Gu, Feng-Tao Li, Ting Wang, Jia Liu & Xian Zheng. (2023) Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway. World Journal of Gastroenterology 29:31, pages 4744-4762.
Crossref
Hao-Kai Chen, Jing Luo, Xiu-Juan Li, Wan-Zhe Liao, Yu-Qi Hu & Xu-Guang Guo. (2023) Serum folate associated with nonalcoholic fatty liver disease and advanced hepatic fibrosis. Scientific Reports 13:1.
Crossref
Yuji Hattori, Hiroya YamadaEiji MunetsunaRyosuke FujiiYoshitaka AndoMirai YamazakiGenki MizunoYoshiki TsuboiYuya IshiharaNaohiro IchinoKeiko SugimotoKeisuke OsakabeHiroaki IshikawaKoji OhashiKoji Suzuki. (2023) The Ratio of miR-122 to miR-20a (miR-122/miR-20a) Is a Useful Minimally Invasive Biomarker for Non-Alcoholic Fatty Liver Disease Detection. Genetic Testing and Molecular Biomarkers 27:8, pages 239-247.
Crossref
Liangge Li, Yiming Qin, Xijian Xin, Shendong Wang, Zhaojun Liu & Xiujing Feng. (2023) The great potential of flavonoids as candidate drugs for NAFLD. Biomedicine & Pharmacotherapy 164, pages 114991.
Crossref
Xiaolei Fang, Jiayu Song, Kaixuan Zhou, Xue Zi, Bin Sun, Huiwei Bao & Lijing Li. (2023) Molecular Mechanism Pathways of Natural Compounds for the Treatment of Non-Alcoholic Fatty Liver Disease. Molecules 28:15, pages 5645.
Crossref
Weimin Lin, Hongbin Song, Jieqiong Shen, Jing Wang, Yue Yang, Yinhua Yang, Jiacheng Cao, Li’e Xue, Fanglu Zhao, Tianfang Xiao & Ruiyi Lin. (2023) Functional role of skeletal muscle-derived interleukin-6 and its effects on lipid metabolism. Frontiers in Physiology 14.
Crossref
Kuai Ma, Xin Hu, Keiki Nambu, Daisuke Ueda, Naotsugu Ichimaru, Masayuki Fujino & Xiao-Kang Li. (2023) Coral calcium carried hydrogen ameliorates the severity of non-alcoholic steatohepatitis induced by a choline deficient high carbohydrate fat-free diet in elderly rats. Scientific Reports 13:1.
Crossref
Mengli Yan, Hui Li, Shiyu Xu, Jinyan Wu, Jiachen Li, Chengju Xiao, Chunheng Mo & Bi-Sen Ding. (2023) Targeting Endothelial Necroptosis Disrupts Profibrotic Endothelial–Hepatic Stellate Cells Crosstalk to Alleviate Liver Fibrosis in Nonalcoholic Steatohepatitis. International Journal of Molecular Sciences 24:14, pages 11313.
Crossref
T. V. Brus, A. G. Vasiliev, S. S. Pyurveev, A. A. Kravtsova & G. S. Veber. (2023) Non-alcoholic fatty liver disease as a risk factor for anemia of chronic inflammation (experimental research). Acta Biomedica Scientifica 8:3, pages 209-215.
Crossref
Limao XU, Chengfeng WU, Chengmin LIU, Zhiyao YE & Juan HUANG. (2023) Therapeutic effect of liraglutide on type 2 diabetic patients with nonalcoholic fatty liver disease. Minerva Surgery 78:4.
Crossref
Cheng Chang, Huicong Li & Ruilin Zhang. (2023) Zebrafish facilitate non‐alcoholic fatty liver disease research: Tools, models and applications. Liver International 43:7, pages 1385-1398.
Crossref
Ingrid L. Ma & Takara L. Stanley. (2023) Growth hormone and nonalcoholic fatty liver disease. Immunometabolism 5:3, pages e00030.
Crossref
Qingyan Ye, Yun Jiang, Di Wu, Jingwen Cai, Zhitian Jiang, Zhen Zhou, Liyan Liu, Qihua Ling, Qian Wang & Gang Zhao. (2023) Atractylodin alleviates nonalcoholic fatty liver disease by regulating Nrf2-mediated ferroptosis. Heliyon 9:7, pages e18321.
Crossref
Chujin Cao, Mengxia Shi, Xiuru Wang, Ying Yao & Rui Zeng. (2023) Effects of probiotics on non-alcoholic fatty liver disease: a review of human clinical trials. Frontiers in Nutrition 10.
Crossref
Ming-Feng Wu, Qing-Hao Xi, Yan Sheng, Yu-Mei Wang, Wan-Yi Wang, Chang-Feng Chi & Bin Wang. (2023) Antioxidant Peptides from Monkfish Swim Bladders: Ameliorating NAFLD In Vitro by Suppressing Lipid Accumulation and Oxidative Stress via Regulating AMPK/Nrf2 Pathway. Marine Drugs 21:6, pages 360.
Crossref
María E. Oliva, Raúl E. Cian, María del Rosario Ferreira, Antonela G. Garzón, Silvina R. Drago & María E. D'Alessandro. (2023) In vivo and in silico study of antioxidant and anti-inflammatory effects on the liver-spleen axis of microencapsulated brewers’ spent grain peptides . Food & Function 14:11, pages 5290-5300.
Crossref
Yusong Gou, Lifei Wang, Jinhan Zhao, Xiaoyi Xu, Hangfei Xu, Fang Xie, Yanjun Wang, Yingmei Feng, Jing Zhang & Yang Zhang. (2023) PNPLA3-I148M Variant Promotes the Progression of Liver Fibrosis by Inducing Mitochondrial Dysfunction. International Journal of Molecular Sciences 24:11, pages 9681.
Crossref
Wenshuai Wang, Yaohan Zhang, Zhiying Wang, Jianjun Zhang & Le Jia. (2023) Ganoderma lucidum polysaccharides improve lipid metabolism against high-fat diet-induced dyslipidemia. Journal of Ethnopharmacology 309, pages 116321.
Crossref
Yongzhi Sun, Congmin Zheng, Ting Li, Xinqian He, Fan Yang, Wenfeng Guo, Jianping Song, Yong Gao, Changsheng Deng & Xinan Huang. (2023) GB1a Activates SIRT6 to Regulate Lipid Metabolism in Mouse Primary Hepatocytes. International Journal of Molecular Sciences 24:11, pages 9540.
Crossref
Xiaofei Xin, Jingjing Li, Wantao Wu, Pengbo Zhao, Yang Yang, Ying Zhu, Lianjie Ren, Chao Qin & Lifang Yin. (2023) ROS-scavenging nanomedicine for “multiple crosstalk” modulation in non-alcoholic fatty liver disease. Biomaterials Science 11:10, pages 3709-3725.
Crossref
Le Bo, Lun Wei, Linling Shi, Chao Luo, Shasha Gao, Anwen Zhou & Caiping Mao. (2023) Altered local RAS in the liver increased the risk of NAFLD in male mouse offspring produced by in vitro fertilization. BMC Pregnancy and Childbirth 23:1.
Crossref
Hao Yu, Siru Yan, Meiyu Jin, Yunfei Wei, Lilei Zhao, Jiaqi Cheng, Lu Ding & Haihua Feng. (2023) Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy. Phytomedicine 113, pages 154746.
Crossref
Sarah Béland-Bonenfant, Alexia Rouland, Jean-Michel Petit & Bruno Vergès. (2023) Concise review of lipidomics in nonalcoholic fatty liver disease. Diabetes & Metabolism 49:3, pages 101432.
Crossref
Soumya Mitra, Amit Kumar Halder, Nilanjan Ghosh, Subhash C. Mandal & M. Natália D.S. Cordeiro. (2023) Multi-model in silico characterization of 3-benzamidobenzoic acid derivatives as partial agonists of Farnesoid X receptor in the management of NAFLD. Computers in Biology and Medicine 157, pages 106789.
Crossref
Zhengyi Zhu, Yuyan Chen, Xueqian Qin, Shujun Liu, Jinglin Wang & Haozhen Ren. (2023) Multidimensional landscape of non‐alcoholic fatty liver disease‐related disease spectrum uncovered by big omics data: Profiling evidence and new perspectives. Smart Medicine 2:2.
Crossref
Yuanfang Sun, Leqi Wang, Lijing Du, Huajun Yu, Yan Tian, Huizi Jin, Shasha Li, Shikai Yan & Xue Xiao. (2023) Investigation on the mechanism of Ginkgo Folium in the treatment of Non-alcoholic Fatty Liver Disease by strategy of network pharmacology and molecular docking. Technology and Health Care 31, pages 209-221.
Crossref
Mohammad Alomari, Mamoon Ur Rashid, Pravallika Chadalavada, Jonathan Ragheb, Hammad Zafar, Zoilo Karim Suarez, Shrouq Khazaaleh, Adalberto Jose Gonzalez & Fernando J Castro. (2023) Comparison between metabolic-associated fatty liver disease and nonalcoholic fatty liver disease: From nomenclature to clinical outcomes. World Journal of Hepatology 15:4, pages 477-496.
Crossref
Meng Wang, Lei Zhang, Hao Yue, Weizhen Cai, Haowen Yin, Yingying Tian, Ping Dong & Jingfeng Wang. (2023) Peptides from Antarctic krill ( Euphausia superba ) ameliorate acute liver injury in mice induced by carbon tetrachloride via activating the Nrf2/HO-1 pathway . Food & Function 14:8, pages 3526-3537.
Crossref
Manouchehr Khoshbaten, Samineh Beheshtirouy, Shahrzad Shayanrad, Afshin Gharekhani & Haleh Rezaee. (2023) Comparison of the efficacy of pioglitazone and metformin on ultrasound grade and liver enzymes level in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial. Drug Research 73:04, pages 232-237.
Crossref
Wanlu Sun, Chao Zhao, Xiaoyan Huang, Baojin Tan, Lina Shangguan, Yi Liu & Hai-Yan Wang. (2023) A novel near-infrared chemodosimeter to monitor the change of carboxylesterase in treatment of diabetes. Sensors and Actuators B: Chemical 381, pages 133416.
Crossref
Yiping Li, Yang Liu, Zhiwei Chen, Kaiyue Tang, Lili Yang, Yuwei Jiang, Jue Wang, Ping Huang, Jianyi Wang, Peiyong Zheng & Haiyan Song. (2023) Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway. Biomedicine & Pharmacotherapy 160, pages 114319.
Crossref
Huimin Liu, Jie Yan, Fengtao Guan, Zhibo Jin, Jiahan Xie, Chongrui Wang, Meihong Liu & Jingsheng Liu. (2023) Zeaxanthin prevents ferroptosis by promoting mitochondrial function and inhibiting the p53 pathway in free fatty acid-induced HepG2 cells. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1868:4, pages 159287.
Crossref
Markus Koponen, Jaana Rysä, Anna-Kaisa Ruotsalainen, Olli Kärkkäinen & Risto O. Juvonen. (2023) Western Diet Decreases Hepatic Drug Metabolism in Male LDLr−/−ApoB100/100 Mice. Journal of Nutrition and Metabolism 2023, pages 1-12.
Crossref
Liudmyla Kiro, Maksym Zak, Inesa Kushnirenko & Oleh Chernyshov. (2023) Complex correction of eating behaviour disorders, anthropometric and physiological indicators in patients with non-alcoholic fatty liver disease on the background of abdominal obesity. Health, sport, rehabilitation 9:1, pages 93-105.
Crossref
Xiang Li, Lei Zhou, Yuying Zheng, Taiping He, Honghui Guo, Jiangbin Li & Jingjing Zhang. (2023) Establishment of a non‐alcoholic fatty liver disease model by high fat diet in adult zebrafish. Animal Models and Experimental Medicine.
Crossref
Yanbo Wang, Zengbo Wang, Yang Wan, Furong Jin, Xiaodan Shi, Zhishuang Xing, Bo Tian & Bailiang Li. (2023) Assessing the in vivo ameliorative effects of Lactobacillus acidophilus KLDS1.0901 for induced non-alcoholic fatty liver disease treatment. Frontiers in Nutrition 10.
Crossref
Chong Song, Xian Long, Jianbin He & Yongpan Huang. (2023) Recent evaluation about inflammatory mechanisms in nonalcoholic fatty liver disease. Frontiers in Pharmacology 14.
Crossref
Mohd Riyazuddin & Arisha Shahid. (2023) Non-alcoholic fatty liver disease – discussed under the light of Unani medicine. Journal of Complementary and Integrative Medicine 20:1, pages 17-23.
Crossref
Ehsan Amini-Salehi, Soheil Hassanipour, Farahnaz Joukar, Amir Ali Daryagasht, Mohammad-Javad Khosousi, Maryam Sadat Aleali, Malek Moien Ansar, Forough Heidarzad, Elham Abdzadeh, Azin Vakilpour & Fariborz Mansour-Ghanaei. (2023) Risk Factors of Non-alcoholic Fatty Liver Disease in the Iranian Adult Population: A Systematic Review and Meta-analysis. Hepatitis Monthly 23:1.
Crossref
Andrea Barrientos-Riosalido, Laia Bertran, Mercè Vilaró-Blay, Carmen Aguilar, Salomé Martínez, Marta Paris, Fàtima Sabench, David Riesco, Jessica Binetti, Daniel Del Castillo, Cristóbal Richart & Teresa Auguet. (2023) The Role of Olfactomedin 2 in the Adipose Tissue–Liver Axis and Its Implication in Obesity-Associated Nonalcoholic Fatty Liver Disease. International Journal of Molecular Sciences 24:6, pages 5221.
Crossref
Fuhang Song, Kai Zhang, Jinpeng Yang, Annette S. Wilson, Caixia Chen & Xiuli Xu. (2023) The Hypolipidemic Characteristics of a Methanol Extract of Fermented Green Tea and Spore of Eurotium cristatum SXHBTBU1934 in Golden Hamsters. Nutrients 15:6, pages 1329.
Crossref
Zongqiang Hu, Hongyu Zhang, Yiting Wang, Boyi Li, Kaiyu Liu, Jianghua Ran & Li Li. (2023) Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease. Lipids in Health and Disease 22:1.
Crossref
Gabriela Yuri, Sofía Sanhueza, Adrián Paredes, Glauco Morales, Mariana Cifuentes & Paulina Ormazabal. (2023) Deleterious liver-adipose crosstalk in obesity: Hydroethanolic extract of Lampaya medicinalis Phil. (Verbenaceae) counteracts fatty acid-induced fibrotic marker expression in human hepatocytes. Molecular and Cellular Endocrinology 564, pages 111882.
Crossref
Weiran Zhang, Daisong Li, Bing Li, Xianming Chu & Bin Kong. (2023) STAT3 as a therapeutic target in the metformin-related treatment. International Immunopharmacology 116, pages 109770.
Crossref
Alejandrina Rodriguez-Hernandez, Marina Delgado-Machuca, Rodolfo Guardado-Mendoza, Martha A. Mendoza-Hernandez, Valery Melnikov, Osiris G. Delgado-Enciso, Daniel Tiburcio-Jimenez, Gabriel Ceja-Espiritu, Gustavo A. Hernandez-Fuentes, Armando Gamboa-Dominguez, Jose Guzman-Esquivel, Margarita L. Martinez-Fierro, Iram P. Rodriguez-Sanchez & Ivan Delgado-Enciso. (2023) Doxycycline Prevents Preclinical Atherosclerosis, Pancreatic Islet Loss and Improves Insulin Secretion after Glycemic Stimulation: Preclinical Study in Individuals with a High-Fat Diet. Biomedicines 11:3, pages 717.
Crossref
Maulana Yusuf Alkandahri, Barolym Tri Pamungkas, Zulpakor Oktoba, Mareetha Zahra Shafirany, Lela Sulastri, Maya Arfania, Ebta Narasukma Anggraeny, Ade Pratiwi, Fitri Dwi Astuti, Indriyani, Siti Yuliani Dewi & Salsa Zulfa Hamidah. (2023) Hepatoprotective Effect of Kaempferol: A Review of the Dietary Sources, Bioavailability, Mechanisms of Action, and Safety. Advances in Pharmacological and Pharmaceutical Sciences 2023, pages 1-16.
Crossref
Dimitrios Kotsos & Konstantinos Tziomalos. (2023) Microsomal Prostaglandin E Synthase-1 and -2: Emerging Targets in Non-Alcoholic Fatty Liver Disease. International Journal of Molecular Sciences 24:3, pages 3049.
Crossref
Mitsutaka Nakashima, Kazufumi Nakamura, Takahiro Nishihara, Keishi Ichikawa, Rie Nakayama, Yoichi Takaya, Norihisa Toh, Satoshi Akagi, Toru Miyoshi, Teiji Akagi & Hiroshi Ito. (2023) Association between Cardiovascular Disease and Liver Disease, from a Clinically Pragmatic Perspective as a Cardiologist. Nutrients 15:3, pages 748.
Crossref
Li LIN, Miao LEI, JiaMan LIN & WenXiang HU. (2022) Advances and applications in liver organoid technology. SCIENTIA SINICA Vitae 53:2, pages 185-195.
Crossref
Jian Tan, Yue-fan Wang, Zhi-hui Dai, Hao-zan Yin, Chen-yang Mu, Si-jie Wang & Fu Yang. (2023) Roles of RNA m6A modification in nonalcoholic fatty liver disease. Hepatology Communications 7:2, pages e0046-e0046.
Crossref
Jessica Maiuolo, Rocco Mollace, Francesca Bosco, Federica Scarano, Francesca Oppedisano, Saverio Nucera, Stefano Ruga, Lorenza Guarnieri, Roberta Macri, Irene Bava, Cristina Carresi, Micaela Gliozzi, Vincenzo Musolino, Antonio Cardamone, Anna Rita Coppoletta, Andrea Barillaro, Virginia Simari, Daniela Salvemini, Ernesto Palma & Vincenzo Mollace. (2023) The Phytochemical Synergistic Properties of Combination of Bergamot Polyphenolic Fraction and Cynara cardunculus Extract in Non-Alcoholic Fatty Liver Disease. Agriculture 13:2, pages 249.
Crossref
Karima Begriche, Clémence Penhoat, Pénélope Bernabeu-Gentey, Julie Massart & Bernard Fromenty. (2023) Acetaminophen-Induced Hepatotoxicity in Obesity and Nonalcoholic Fatty Liver Disease: A Critical Review. Livers 3:1, pages 33-53.
Crossref
Liuqiao Sun, Xuying Tan, Xiaoping Liang, Hangjun Chen, Qian Ou, Qiongmei Wu, Xinxue Yu, Hanqing Zhao, Qiaoli Huang, Zehua Yi, Jun Wei, Feng Wu, Huilian Zhu & Lijun Wang. (2023) Maternal Betaine Supplementation Mitigates Maternal High Fat Diet-Induced NAFLD in Offspring Mice through Gut Microbiota. Nutrients 15:2, pages 284.
Crossref
Anqi Wang, Kexin Zhang, Chunyan Fu, Changming Zhou, Zhengui Yan & Xuelan Liu. (2023) Alleviation effect of conjugated linoleic acid on estradiol benzoate induced fatty liver hemorrhage syndrome in Hy-line male chickens. Journal of Animal Science 101.
Crossref
Jing Wu, Yun-ge Lou, Xu-le Yang, Rui Wang, Ran Zhang, Ji-ye Aa, Guang-ji Wang & Yuan Xie. (2022) Silybin regulates P450s activity by attenuating endoplasmic reticulum stress in mouse nonalcoholic fatty liver disease. Acta Pharmacologica Sinica 44:1, pages 133-144.
Crossref
Xiangfu Jiang, Yu Li, Dongdong Fu, Tingyu You, Shuai Wu, Jiao Xin, Jiagen Wen, Yan Huang & Chengmu Hu. (2023) Caveolin-1 ameliorates acetaminophen-aggravated inflammatory damage and lipid deposition in non-alcoholic fatty liver disease via the ROS/TXNIP/NLRP3 pathway. International Immunopharmacology 114, pages 109558.
Crossref
Belinda J. Petri, Kellianne M. Piell, Banrida Wahlang, Kimberly Z. Head, Kalina Andreeva, Eric C. Rouchka, Matthew C. Cave & Carolyn M. Klinge. (2023) Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease. Environmental Research 216, pages 114686.
Crossref
Zhe Jiang, Hao Sun, Jiaen Miao, Qiyu Sheng, Jia Xu, Zhe Gao, Xie Zhang, Yufei Song & Kuihao Chen. (2023) The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway. Biochemical and Biophysical Research Communications 640, pages 183-191.
Crossref
Tom Wiggins, Miriam Adebibe & John Loy. 2023. Obesity, Bariatric and Metabolic Surgery. Obesity, Bariatric and Metabolic Surgery 249 265 .
Ali Mahzari. (2022) Artificial intelligence in nonalcoholic fatty liver disease. Egyptian Liver Journal 12:1.
Crossref
Lvying Wu, Lei Xing, Yake Zou, Zichen Wang, Yuanyuan Gou, Lei Zhang & Su Guan. (2022) UPLC-QTOF-MS Based Comparison of Rotundic Acid Metabolic Profiles in Normal and NAFLD Rats. Metabolites 13:1, pages 38.
Crossref
Yang Bao, Xiao Han, Da Liu, Zhaolin Tan & Yongzhi Deng. (2022) Gut microbiota: The key to the treatment of metabolic syndrome in traditional Chinese medicine – a case study of diabetes and nonalcoholic fatty liver disease. Frontiers in Immunology 13.
Crossref
Saiful Bahri Talip, Muhammad Hamdi Mahmood, Azam Hafizi Azmi Murad, Charisma Demai Edmand, Vimal Gengatharan & Yvonne Kar Kiat Ho. (2022) A Retrospective Study On Liver Function Tests & Urine Protein in Presumptive Non-Alcoholic Fatty Liver Cases Performed in A Local Private Laboratory Service. Trends in Undergraduate Research 5:2, pages i1-8.
Crossref
Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch & Uta Dahmen. (2022) Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism. Scientific Reports 12:1.
Crossref
Shu Niu, Shuchun Chen, Xing Chen, Qingjuan Ren, Lin Yue, Xiaoyu Pan, Huiying Zhao, Zelin Li & Xiaoyi Chen. (2022) Semaglutide ameliorates metabolism and hepatic outcomes in an NAFLD mouse model. Frontiers in Endocrinology 13.
Crossref
Betül Yakıştıran, Atakan Tanaçan, Orhan Altınboğa, Sarkhan Elbayiyev, Fuat Emre Canpolat & Aykan Yücel. (2022) Fetal pulmonary artery Doppler parameters in pregnancies complicated with intrahepatic cholestasis of pregnancy: a prospective case-control study. Journal of the Turkish-German Gynecological Association 23:4, pages 249-254.
Crossref
Yamei Duan, Jiayou Luo, Xiongfeng Pan, Jia Wei, Xiang Xiao, Jingya Li & Miyang Luo. (2022) Association between inflammatory markers and non-alcoholic fatty liver disease in obese children. Frontiers in Public Health 10.
Crossref
Gianni BELCARO, David M. COX, M. Rosaria CESARONE, Giuseppe GIZZI, Luciano PELLEGRINI, Claudia SCIPIONE, Valeria SCIPIONE, Mark DUGALL, Shu HU, Marcello CORSI, Beatrice FERAGALLI & Roberto COTELLESE. (2022) Effects of Robuvit® on the progression of non-alcoholic fatty liver disease. Minerva Gastroenterology 68:4.
Crossref
Yunqing Zeng, Ruyue Cao, Ziwen Tao & Yanjing Gao. (2022) Association between the severity of metabolic dysfunction-associated fatty liver disease and the risk of colorectal neoplasm: a systematic review and meta-analysis. Lipids in Health and Disease 21:1.
Crossref
Roos AchterberghLaureen A. LammersHeinz-Josef KlümpenRon A. A. Mathôt & Johannes A. Romijn. (2022) Short-Term High-Fat Diet Alters Acetaminophen Metabolism in Healthy Individuals. Therapeutic Drug Monitoring 44:6, pages 797-804.
Crossref
Mi XieLiying GaoZhiming LiuRuiying YuanDongzhi ZhuomaDikye TseringYuefei WangShan HuangBin Li. (2022) Malus toringoides (Rehd.) Hughes Ameliorates Nonalcoholic Fatty Liver Disease with Diabetes via Downregulation of SREBP-1c and the NF- κ B Pathway In Vivo and In Vitro . Journal of Medicinal Food 25:12, pages 1112-1125.
Crossref
Tengfei Wang, Yufei Xiao, Ronglong Luo, Yingjie Wang, Mengyun Zou, Yingfei Sun, Lulu Wang, Qiao Guo & Xiuli Peng. (2022) Host resistance to Mycoplasma gallisepticum infection is enhanced by inhibiting PI3K/Akt pathway in Andrographolide-treating chickens. International Immunopharmacology 113, pages 109419.
Crossref
Wenjing Xu, Changting Cui, Chunmei Cui, Zhenzhen Chen, Haizeng Zhang, Qinghua Cui, Guoheng Xu, Jianglin Fan, Yu Han, Liangjie Tang, Giovanni Targher, Christopher D. Byrne, Ming‐Hua Zheng, Liming Yang, Jun Cai & Bin Geng. (2022) Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor. Hepatology 76:6, pages 1794-1810.
Crossref
Wenwen Lv, Xiyang Tan, Xiaochen Chen, Tingting Hu, Jiayuan Jiang, Qiang Li, Xiao‐yun Chen, Hongsheng Tan & Biyun Qian. (2022) D ‐Limonene for regulating metabolism‐associated fatty liver disease (MAFLD) and analysis of the TCM constitution: A protocol for an exploratory, randomized, double‐blind, placebo‐controlled trial (DL‐MAFLD‐TCM) . Food Frontiers 3:4, pages 550-559.
Crossref
Aihua Deng, Fengying Liu, Xuchong Tang, Yun Wang, Peng Xie, Qifu Yang & Bing Xiao. (2022) Water extract from artichoke ameliorates high-fat diet-induced non-alcoholic fatty liver disease in rats. BMC Complementary Medicine and Therapies 22:1.
Crossref
Ying Shi, Xiaoguang Yang, Shuyue Wang, Yulun Wu, Lihua Zheng, Yufang Tang, Yanhang Gao & Junqi Niu. (2022) Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model. Stem Cell Research & Therapy 13:1.
Crossref
Yajie Fu, Yanzhi Zhou, Linhu Shen, Xuewen Li, Haorui Zhang, Yeqi Cui, Ke Zhang, Weiguo Li, Wei-dong Chen, Shizhen Zhao, Yunfu Li & Wenling Ye. (2022) Diagnostic and therapeutic strategies for non-alcoholic fatty liver disease. Frontiers in Pharmacology 13.
Crossref
Binjing Pan, Jing Cai, Pingping Zhao, Jingfang Liu, Songbo Fu, Gaojing Jing, Qianglong Niu & Qiong Li. (2022) Relationship between prevalence and risk of osteoporosis or osteoporotic fracture with non-alcoholic fatty liver disease: A systematic review and meta-analysis. Osteoporosis International 33:11, pages 2275-2286.
Crossref
Qi Gong, Xie Zhang, Yixuan Sun, Jixiang Shen, Xiuping Li, Chao Xue & Zhihua Liu. (2022) Transcription factor EB inhibits non-alcoholic fatty liver disease through fibroblast growth factor 21. Journal of Molecular Medicine 100:11, pages 1587-1597.
Crossref
Stephen H. Curry & Robin Whelpton. 2022. Drug Disposition and Pharmacokinetics. Drug Disposition and Pharmacokinetics 335 360 .
Youcai Tang, Xuecui Yin & Yuying Ma. 2022. Hepatotoxicity. Hepatotoxicity.
Nikhil Y. Patil, Iulia Rus, Emma Downing, Ashok Mandala, Jacob E. Friedman & Aditya D. Joshi. (2022) Cinnabarinic Acid Provides Hepatoprotection Against Nonalcoholic Fatty Liver Disease. Journal of Pharmacology and Experimental Therapeutics 383:1, pages 32-43.
Crossref
Rong Xiang, Yuxing Liu, Liangliang Fan, Boyue Jiang & Fang Wang. (2022) RNA adenosine deaminase (ADAR1) alleviates high-fat diet-induced nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome. Laboratory Investigation 102:10, pages 1088-1100.
Crossref
Youdong Li, Yong-Jiang Xu, Chin Ping Tan & Yuanfa Liu. (2022) Sinapine improves LPS-induced oxidative stress in hepatocytes by down-regulating MCJ protein expression. Life Sciences 306, pages 120828.
Crossref
Shipeng Zhou, Huimin You, Shuting Qiu, Dawei Yu, Yan Bai, Jincan He, Hua Cao, Qishi Che, Jiao Guo & Zhengquan Su. (2022) A new perspective on NAFLD: Focusing on the crosstalk between peroxisome proliferator-activated receptor alpha (PPARα) and farnesoid X receptor (FXR). Biomedicine & Pharmacotherapy 154, pages 113577.
Crossref
Zhen LiXin MaoXiuxiu CuiTingting YuMengmeng ZhangXiya LiGuangsen Li. (2022) Evaluate the elasticity of carotid artery in the type 2 diabetes mellitus patients with nonalcoholic fatty liver disease by two-dimensional strain imaging. Medicine 101:39, pages e30738.
Crossref
Toini Pemmari, Mari Hämäläinen, Riitta Ryyti, Rainer Peltola & Eeva Moilanen. (2022) Dried Bilberry (Vaccinium myrtillus L.) Alleviates the Inflammation and Adverse Metabolic Effects Caused by a High-Fat Diet in a Mouse Model of Obesity. International Journal of Molecular Sciences 23:19, pages 11021.
Crossref
Panli Tan, Li Jin, Xiang Qin & Beihui He. (2022) Natural flavonoids: Potential therapeutic strategies for non-alcoholic fatty liver disease. Frontiers in Pharmacology 13.
Crossref
Kailin Yang, Junpeng Chen, Tianqing Zhang, Xiao Yuan, Anqi Ge, Shanshan Wang, Hao Xu, Liuting Zeng & Jinwen Ge. (2022) Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis. Frontiers in Immunology 13.
Crossref
Daniela Gabbia, Marco Roverso, Ilaria Zanotto, Martina Colognesi, Katia Sayaf, Samantha Sarcognato, Diletta Arcidiacono, Alice Zaramella, Stefano Realdon, Nicola Ferri, Maria Guido, Francesco Paolo Russo, Sara Bogialli, Maria Carrara & Sara De Martin. (2022) A Nutraceutical Formulation Containing Brown Algae Reduces Hepatic Lipid Accumulation by Modulating Lipid Metabolism and Inflammation in Experimental Models of NAFLD and NASH. Marine Drugs 20:9, pages 572.
Crossref
Giovanni Tarantino, Mauro Cataldi & Vincenzo Citro. (2022) Could Alcohol Abuse and Dependence on Junk Foods Inducing Obesity and/or Illicit Drug Use Represent Danger to Liver in Young People with Altered Psychological/Relational Spheres or Emotional Problems?. International Journal of Molecular Sciences 23:18, pages 10406.
Crossref
Yutian Wang, Junzi Wu & Anhua Shi. (2022) Literature Review on the Use of Herbal Extracts in the Treatment of Non- Alcoholic Fatty Liver Disease. Endocrine, Metabolic & Immune Disorders - Drug Targets 22:11, pages 1123-1145.
Crossref
Yongxiang Wang, Yuanjing Li, Keke Liu, Xiaolei Han, Yi Dong, Xiaojie Wang, Mingqi Wang, Lin Cong, Qinghua Zhang, Shi Tang, Tingting Hou, Cuicui Liu, Lin Song, Xiaojuan Han, Davide L. Vetrano, Yifeng Du & Chengxuan Qiu. (2022) Nonalcoholic fatty liver disease, serum cytokines, and dementia among rural‐dwelling older adults in China: A population‐based study. European Journal of Neurology 29:9, pages 2612-2621.
Crossref
Guoquan Yin, Chen Zhao & Weiya Pei. (2022) Crosstalk between macrophages and innate lymphoid cells (ILCs) in diseases. International Immunopharmacology 110, pages 108937.
Crossref
Nabila Bourebaba, ThuHa Ngo, Agnieszka Śmieszek, Lynda Bourebaba & Krzysztof Marycz. (2022) Sex hormone binding globulin as a potential drug candidate for liver-related metabolic disorders treatment. Biomedicine & Pharmacotherapy 153, pages 113261.
Crossref
Somaya Z. Mansour, Enas M. Moustafa & Fatma S.M. Moawed. (2022) Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats. Cell Stress and Chaperones 27:5, pages 499-511.
Crossref
Liu Han, Shifeng Fu, Jianglei Li, Deliang Liu & Yuyong Tan. (2022) Association between grip strength and non-alcoholic fatty liver disease: A systematic review and meta-analysis. Frontiers in Medicine 9.
Crossref
Apurva Lad, Jonathan Hunyadi, Jacob Connolly, Joshua D. Breidenbach, Fatimah K. Khalaf, Prabhatchandra Dube, Shungang Zhang, Andrew L. Kleinhenz, David Baliu-Rodriguez, Dragan Isailovic, Terry D. HindsJr.Jr., Cara Gatto-Weis, Lauren M. Stanoszek, Thomas M. Blomquist, Deepak Malhotra, Steven T. Haller & David J. Kennedy. (2022) Antioxidant Therapy Significantly Attenuates Hepatotoxicity following Low Dose Exposure to Microcystin-LR in a Murine Model of Diet-Induced Non-Alcoholic Fatty Liver Disease. Antioxidants 11:8, pages 1625.
Crossref
Zeyu Li, Kanglin Wu, Yi Zou, Wei Gong, Peng Wang & Hong Wang. (2022) PREX1 depletion ameliorates high-fat diet-induced non-alcoholic fatty liver disease in mice and mitigates palmitic acid-induced hepatocellular injury via suppressing the NF-κB signaling pathway. Toxicology and Applied Pharmacology 448, pages 116074.
Crossref

Displaying 200 of 402 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.