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Inhalation Toxicology
International Forum for Respiratory Research
Volume 21, 2009 - Issue 2
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Research Article

Development of a Short-Term Inhalation Test in the Rat Using Nano-Titanium Dioxide as a Model Substance

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Pages 102-118 | Received 10 Jun 2008, Accepted 21 Jul 2008, Published online: 01 Feb 2009

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Eugenia Cordelli, Jana Keller, Patrizia Eleuteri, Paola Villani, Lan Ma-Hock, Markus Schulz, Robert Landsiedel & Francesca Pacchierotti. (2017) No genotoxicity in rat blood cells upon 3- or 6-month inhalation exposure to CeO 2 or BaSO 4 nanomaterials . Mutagenesis 32:1, pages 13-22.
Crossref
Laurent Gaté, Clémence Disdier, Frédéric Cosnier, François Gagnaire, Jérôme Devoy, Wadad Saba, Emilie Brun, Monique Chalansonnet & Aloise Mabondzo. (2017) Biopersistence and translocation to extrapulmonary organs of titanium dioxide nanoparticles after subacute inhalation exposure to aerosol in adult and elderly rats. Toxicology Letters 265, pages 61-69.
Crossref
Robert Landsiedel, Ursula G. Sauer & Wim H. de Jong. 2017. Adverse Effects of Engineered Nanomaterials. Adverse Effects of Engineered Nanomaterials 189 222 .
Sandra Vranic, Ilse Gosens, Nicklas Raun Jacobsen, Keld A. Jensen, Bas Bokkers, Ali Kermanizadeh, Vicki Stone, Armelle Baeza-Squiban, Flemming R. Cassee, Lang Tran & Sonja Boland. (2016) Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO2 nanoparticles. Archives of Toxicology 91:1, pages 353-363.
Crossref
Martin Wiemann, Antje Vennemann, Ursula G. Sauer, Karin Wiench, Lan Ma-Hock & Robert Landsiedel. (2016) An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials. Journal of Nanobiotechnology 14:1.
Crossref
Robert Landsiedel. (2016) Concern-driven integrated approaches for the grouping, testing and assessment of nanomaterials. Environmental Pollution 218, pages 1376-1380.
Crossref
Robert Landsiedel. (2016) Prüfung der Sicherheit von Nanomaterialien. BIOspektrum 22:5, pages 538-539.
Crossref
Muhammad Shakeel, Farhat Jabeen, Samina Shabbir, Muhammad Saleem Asghar, Muhammad Saleem Khan & Abdul Shakoor Chaudhry. (2015) Toxicity of Nano-Titanium Dioxide (TiO2-NP) Through Various Routes of Exposure: a Review. Biological Trace Element Research 172:1, pages 1-36.
Crossref
Josje H.E. Arts, Muhammad-Adeel Irfan, Athena M. Keene, Reinhard Kreiling, Delina Lyon, Monika Maier, Karin Michel, Nicole Neubauer, Thomas Petry, Ursula G. Sauer, David Warheit, Karin Wiench, Wendel Wohlleben & Robert Landsiedel. (2016) Case studies putting the decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping) into practice. Regulatory Toxicology and Pharmacology 76, pages 234-261.
Crossref
Hideki Senoh, Hirokazu Kano, Masaaki Suzuki, Hitomi Kondo, Kenji Takanobu, Yumi Umeda, Shigetoshi Aiso & Shoji Fukushima. (2016) Limited application of the three drug-mixed anesthesia for bronchoalveolar lavage fluid sampling. Sangyo Eiseigaku Zasshi SANGYO EISEIGAKU ZASSHI 58:1, pages 21-24.
Crossref
Ashok K. Singh. 2016. Engineered Nanoparticles. Engineered Nanoparticles 451 514 .
Gerald Bachler, Sabrina Losert, Yuki Umehara, Natalie von Goetz, Laura Rodriguez-Lorenzo, Alke Petri-Fink, Barbara Rothen-Rutishauser & Konrad Hungerbuehler. (2015) Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments. Particle and Fibre Toxicology 12:1.
Crossref
Francisco Silva, Pedro Arezes & Paul Swuste. (2015) Risk assessment in a research laboratory during sol–gel synthesis of nano-TiO 2. Safety Science 80, pages 201-212.
Crossref
Elena Maser, Markus Schulz, Ursula G. Sauer, Martin Wiemann, Lan Ma-Hock, Wendel Wohlleben, Andrea Hartwig & Robert Landsiedel. (2015) In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 794, pages 57-74.
Crossref
Götz A. Westphal, Isabell Schremmer, Alexander Rostek, Kateryna Loza, Nina Rosenkranz, Thomas Brüning, Matthias Epple & Jürgen Bünger. (2015) Particle-induced cell migration assay (PICMA): A new in vitro assay for inflammatory particle effects based on permanent cell lines. Toxicology in Vitro 29:5, pages 997-1005.
Crossref
Sung Gu Han, Jong Seong Lee, Kangho Ahn, Yong Soon Kim, Jin Kwon Kim, Ji Huyn Lee, Jae Hoon Shin, Ki Soo Jeon, Wan Seob Cho, Nam Woong Song, Mary Gulumian, Beom Soo Shin & Il Je Yu. (2014) Size-dependent clearance of gold nanoparticles from lungs of Sprague–Dawley rats after short-term inhalation exposure. Archives of Toxicology 89:7, pages 1083-1094.
Crossref
Teresa Coccini, Stefania Grandi, Davide Lonati, Carlo Locatelli & Uliana De Simone. (2015) Comparative cellular toxicity of titanium dioxide nanoparticles on human astrocyte and neuronal cells after acute and prolonged exposure. NeuroToxicology 48, pages 77-89.
Crossref
Alexandra Noël & Ginette Truchon. (2015) Inhaled Titanium Dioxide Nanoparticles: A Review of Their Pulmonary Responses with Particular Focus on the Agglomeration State. Nano LIFE 05:01, pages 1450008.
Crossref
Josje H.E. Arts, Mackenzie Hadi, Muhammad-Adeel Irfan, Athena M. Keene, Reinhard Kreiling, Delina Lyon, Monika Maier, Karin Michel, Thomas Petry, Ursula G. Sauer, David Warheit, Karin Wiench, Wendel Wohlleben & Robert Landsiedel. (2015) A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping). Regulatory Toxicology and Pharmacology 71:2, pages S1-S27.
Crossref
Massimiliano G. Bianchi, Manfredi Allegri, Anna L. Costa, Magda Blosi, Davide Gardini, Camilla Del Pivo, Adriele Prina-Mello, Luisana Di Cristo, Ovidio Bussolati & Enrico Bergamaschi. (2015) Titanium dioxide nanoparticles enhance macrophage activation by LPS through a TLR4-dependent intracellular pathway. Toxicology Research 4:2, pages 385-398.
Crossref
Sajid Bashir & Jingbo Liu. 2015. Advanced Nanomaterials and their Applications in Renewable Energy. Advanced Nanomaterials and their Applications in Renewable Energy 367 421 .
Jiangxue Wang & Yubo Fan. (2014) Lung Injury Induced by TiO2 Nanoparticles Depends on Their Structural Features: Size, Shape, Crystal Phases, and Surface Coating. International Journal of Molecular Sciences 15:12, pages 22258-22278.
Crossref
Nagarjun Konduru, Jana Keller, Lan Ma-Hock, Sibylle Gröters, Robert Landsiedel, Thomas C Donaghey, Joseph D Brain, Wendel Wohlleben & Ramon M Molina. (2014) Biokinetics and effects of barium sulfate nanoparticles. Particle and Fibre Toxicology 11:1.
Crossref
Bernd Nowack, Nicole C Mueller, Harald F Krug & Peter Wick. (2014) How to consider engineered nanomaterials in major accident regulations?. Environmental Sciences Europe 26:1.
Crossref
Robert Landsiedel, Ursula G Sauer, Lan Ma-Hock, Jürgen Schnekenburger & Martin Wiemann. (2014) Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies . Nanomedicine 9:16, pages 2557-2585.
Crossref
Naohide Shinohara, Yutaka Oshima, Toshio Kobayashi, Nobuya Imatanaka, Makoto Nakai, Takayuki Ichinose, Takeshi Sasaki, Guihua Zhang, Hiroko Fukui & Masashi Gamo. (2014) Dose-dependent clearance kinetics of intratracheally administered titanium dioxide nanoparticles in rat lung. Toxicology 325, pages 1-11.
Crossref
Jana Keller, Wendel Wohlleben, Lan Ma-Hock, Volker Strauss, Sibylle Gröters, Karin Küttler, Karin Wiench, Christiane Herden, Günter Oberdörster, Bennard van Ravenzwaay & Robert Landsiedel. (2014) Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria. Archives of Toxicology 88:11, pages 2033-2059.
Crossref
Katharina Bräutigam, Thomas Bocklitz, Anja Silge, Christian Dierker, Rainer Ossig, Jürgen Schnekenburger, Dana Cialla, Petra Rösch & Jürgen Popp. (2014) Comparative two- and three-dimensional analysis of nanoparticle localization in different cell types by Raman spectroscopic imaging. Journal of Molecular Structure 1073, pages 44-50.
Crossref
Hyejin Kim & Kwangsik Park. (2014) Excretion, Tissue Distribution and Toxicities of Titanium Oxide Nanoparticles in Rats after Oral Administration over Five Consecutive Days. Korean Journal of Environmental Health Sciences 40:4, pages 294-303.
Crossref
Ursula G. Sauer, Sandra Vogel, Alexandra Aumann, Annemarie Hess, Susanne N. Kolle, Lan Ma-Hock, Wendel Wohlleben, Martina Dammann, Volker Strauss, Silke Treumann, Sibylle Gröters, Karin Wiench, Bennard van Ravenzwaay & Robert Landsiedel. (2014) Applicability of rat precision-cut lung slices in evaluating nanomaterial cytotoxicity, apoptosis, oxidative stress, and inflammation. Toxicology and Applied Pharmacology 276:1, pages 1-20.
Crossref
L. Ma-Hock, P.M.A. Farias, T. Hofmann, A.C.D.S. Andrade, J.N. Silva, T.M.S. Arnaud, W. Wohlleben, V. Strauss, S. Treumann, C.R. Chaves, S. Gröters, R. Landsiedel & B. van Ravenzwaay. (2014) Short term inhalation toxicity of a liquid aerosol of glutaraldehyde-coated CdS/Cd(OH)2 core shell quantum dots in rats. Toxicology Letters 225:1, pages 20-26.
Crossref
Gil Soon CHOI, Chulho OAK, Bong-Kwon CHUN, Donald WILSON, Tae Won JANG, Hee-Kyoo KIM, Mannhong JUNG, Engin TUTKUN & Eun-Kee PARK. (2014) Titanium Dioxide Exposure Induces Acute Eosinophilic Lung Inflammation in Rabbits. Industrial Health 52:4, pages 289-295.
Crossref
Robert Landsiedel, Lan Ma-Hock, Thomas Hofmann, Martin Wiemann, Volker Strauss, Silke Treumann, Wendel Wohlleben, Sibylle Gröters, Karin Wiench & Bennard van Ravenzwaay. (2014) Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials. Particle and Fibre Toxicology 11:1, pages 16.
Crossref
Yunli Zhao, Qiuli Wu, Meng Tang & Dayong Wang. (2014) The in vivo underlying mechanism for recovery response formation in nano-titanium dioxide exposed Caenorhabditis elegans after transfer to the normal condition. Nanomedicine: Nanotechnology, Biology and Medicine 10:1, pages 89-98.
Crossref
Alan J. Kennedy, Steve Diamond, Jacob K. Stanley, Jessica Coleman, Jeffery A. Steevens, Mark A. Chappell, Jennifer Laird & Amy Bednar. 2014. Nanotechnology Environmental Health and Safety. Nanotechnology Environmental Health and Safety 117 151 .
Lan Ma-Hock, Thomas Hofmann, Robert Landsiedel & Bennard van Ravenzwaay. 2014. Quantum Dots: Applications in Biology. Quantum Dots: Applications in Biology 207 212 .
Alexandra Noël, Michel Charbonneau, Yves Cloutier, Robert Tardif & Ginette Truchon. (2013) Rat pulmonary responses to inhaled nano-TiO2: effect of primary particle size and agglomeration state. Particle and Fibre Toxicology 10:1.
Crossref
Hongbo Shi, Ruth Magaye, Vincent Castranova & Jinshun Zhao. (2013) Titanium dioxide nanoparticles: a review of current toxicological data. Particle and Fibre Toxicology 10:1.
Crossref
Xuhong Chang, Yu Zhang, Meng Tang & Bei Wang. (2013) Health effects of exposure to nano-TiO2: a meta-analysis of experimental studies. Nanoscale Research Letters 8:1.
Crossref
Lindsay Tomlinson, Laura I. Boone, Lila Ramaiah, Kelley A. Penraat, Barbara R. von Beust, Mehrdad Ameri, Florence M. Poitout-Belissent, Kurt Weingand, Heather C. Workman, Adam D. Aulbach, Dennis J. Meyer, Diane E. Brown, Amy L. MacNeill, Anne Provencher Bolliger & Denise I. Bounous. (2013) Best practices for veterinary toxicologic clinical pathology, with emphasis on the pharmaceutical and biotechnology industries. Veterinary Clinical Pathology 42:3, pages 252-269.
Crossref
D. Broßell, S. Tröller, N. Dziurowitz, S. Plitzko, G. Linsel, C. Asbach, N. Azong-Wara, H. Fissan & A. Schmidt-Ott. (2013) A thermal precipitator for the deposition of airborne nanoparticles onto living cells—Rationale and development. Journal of Aerosol Science 63, pages 75-86.
Crossref
Candace Su-Jung Tsai. (2013) Potential inhalation exposure and containment efficiency when using hoods for handling nanoparticles. Journal of Nanoparticle Research 15:9.
Crossref
Robert Landsiedel. 2013. Nanomaterials. Nanomaterials 43 48 .
Ann Hubbs, Dale W. Porter, Robert Mercer, Vincent Castranova, Linda Sargent & Krishnan Sriram. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology 1373 1419 .
Ndeke Musee, Lucky Sikhwivhilu & Mary Gulumian. 2013. Chemistry for Sustainable Development in Africa. Chemistry for Sustainable Development in Africa 123 158 .
Shichang Liu & Zhuo Yang. 2013. Oxidative Stress and Nanotechnology. Oxidative Stress and Nanotechnology 135 145 .
Soonjin Kwon, Young-Su Yang, Hyo-Seon Yang, Jinsoo Lee, Min-Sung Kang, Byoung-Seok Lee, Kyuhong Lee & Chang-Woo Song. (2012) Nasal and Pulmonary Toxicity of Titanium Dioxide Nanoparticles in Rats. Toxicological Research 28:4, pages 217-224.
Crossref
A. Noël, K. Maghni, Y. Cloutier, C. Dion, K.J. Wilkinson, S. Hallé, R. Tardif & G. Truchon. (2012) Effects of inhaled nano-TiO2 aerosols showing two distinct agglomeration states on rat lungs. Toxicology Letters 214:2, pages 109-119.
Crossref
Hideo Nakane. (2011) Translocation of particles deposited in the respiratory system: a systematic review and statistical analysis. Environmental Health and Preventive Medicine 17:4, pages 263-274.
Crossref
Robert Landsiedel, Eric Fabian, Lan Ma-Hock, Wendel Wohlleben, Karin Wiench, Franz Oesch & Ben van Ravenzwaay. (2012) Toxico-/biokinetics of nanomaterials. Archives of Toxicology 86:7, pages 1021-1060.
Crossref
Michael Bräu, Lan Ma-Hock, Christoph Hesse, Luc Nicoleau, Volker Strauss, Silke Treumann, Karin Wiench, Robert Landsiedel & Wendel Wohlleben. (2012) Nanostructured calcium silicate hydrate seeds accelerate concrete hardening: a combined assessment of benefits and risks. Archives of Toxicology 86:7, pages 1077-1087.
Crossref
Christoph L. Klein, Karin Wiench, Martin Wiemann, Lan Ma-Hock, Ben van Ravenzwaay & Robert Landsiedel. (2012) Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies. Archives of Toxicology 86:7, pages 1137-1151.
Crossref
Robert Landsiedel, Lan Ma-Hock, Hans-Juergen Haussmann, Ben van Ravenzwaay, Martin Kayser & Karin Wiench. (2012) Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 4:4, pages 399-413.
Crossref
Reza Mostofi, Alexandra Noël, Fariborz Haghighat, Ali Bahloul, Jaime Lara & Yves Cloutier. (2012) Impact of two particle measurement techniques on the determination of N95 class respirator filtration performance against ultrafine particles. Journal of Hazardous Materials 217-218, pages 51-57.
Crossref
Alex Weir, Paul Westerhoff, Lars Fabricius, Kiril Hristovski & Natalie von Goetz. (2012) Titanium Dioxide Nanoparticles in Food and Personal Care Products. Environmental Science & Technology 46:4, pages 2242-2250.
Crossref
Barbara Malczewska‐Toth. 2003. Patty's Toxicology. Patty's Toxicology 427 474 .
Chikara KADOYA, Akira OGAMI, Yasuo MORIMOTO, Toshihiko MYOJO, Takako OYABU, Kenichiro NISHI, Makoto YAMAMOTO, Motoi TODOROKI & Isamu TANAKA. (2012) Analysis of Bronchoalveolar Lavage Fluid Adhering to Lung Surfactant. Industrial Health 50:1, pages 31-36.
Crossref
Lan Ma-Hock, Robert Landsiedel, Karin Wiench, Dominik Geiger, Volker Strauss, Sibylle Gröters, Bennard van Ravenzwaay, Matthias Gerst, Wendel Wohlleben & Gertrud Scherer. (2012) Short-Term Rat Inhalation Study With Aerosols of Acrylic Ester-Based Polymer Dispersions Containing a Fraction of Nanoparticles. International Journal of Toxicology 31:1, pages 46-57.
Crossref
Ivo Iavicoli, Veruscka Leso & Antonio Bergamaschi. (2012) Toxicological Effects of Titanium Dioxide Nanoparticles: A Review of In Vivo Studies . Journal of Nanomaterials 2012, pages 1-36.
Crossref
Antonio Pietroiusti. (2012) Health implications of engineered nanomaterials. Nanoscale 4:4, pages 1231.
Crossref
L. Ma-Hock, S. Brill, W. Wohlleben, P.M.A. Farias, C.R. Chaves, D.P.L.A. Tenório, A. Fontes, B.S. Santos, R. Landsiedel, V. Strauss, S. Treumann & B. van Ravenzwaay. (2012) Short term inhalation toxicity of a liquid aerosol of CdS/Cd(OH)2 core shell quantum dots in male Wistar rats. Toxicology Letters 208:2, pages 115-124.
Crossref
Ken Donaldson & Craig A. Poland. 2012. Adverse Effects of Engineered Nanomaterials. Adverse Effects of Engineered Nanomaterials 121 137 .
Ursula G. Sauer. (2011) Eating Nanomaterials: Cruelty-free and Safe? The EFSA Guidance on Risk Assessment of Nanomaterials in Food and Feed. Alternatives to Laboratory Animals 39:6, pages 567-575.
Crossref
Wendel Wohlleben, Sandra Brill, Matthias W. Meier, Michael Mertler, Gerhard Cox, Sabine Hirth, Bernhard von Vacano, Volker Strauss, Silke Treumann, Karin Wiench, Lan Ma-Hock & Robert Landsiedel. (2011) On the Lifecycle of Nanocomposites: Comparing Released Fragments and their In-Vivo Hazards from Three Release Mechanisms and Four Nanocomposites. Small 7:16, pages 2384-2395.
Crossref
Sabina Halappanavar, Petra Jackson, Andrew Williams, Keld A. Jensen, Karin S. Hougaard, Ulla Vogel, Carole L. Yauk & Håkan Wallin. (2011) Pulmonary response to surface‐coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study. Environmental and Molecular Mutagenesis 52:6, pages 425-439.
Crossref
Christine Schulze, Ulrich F. Schaefer, Christian A. Ruge, Wendel Wohlleben & Claus-Michael Lehr. (2011) Interaction of metal oxide nanoparticles with lung surfactant protein A. European Journal of Pharmaceutics and Biopharmaceutics 77:3, pages 376-383.
Crossref
Robert Landsiedel, Lan Ma-Hock, Alexandra Kroll, Daniela Hahn, Jürgen Schnekenburger, Karin Wiench & Wendel Wohlleben. (2010) Testing Metal-Oxide Nanomaterials for Human Safety. Advanced Materials 22:24, pages 2601-2627.
Crossref
Lan Ma-Hock, Silke Treumann, Volker Strauss, Sandra Brill, Frederic Luizi, Michael Mertler, Karin Wiench, Armin O. Gamer, Bennard van Ravenzwaay & Robert Landsiedel. (2009) Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months. Toxicological Sciences 112:2, pages 468-481.
Crossref
Katja Nau & Harald F Krug. (2009) The NanoCare project: A German initiative on health aspects of synthetic nanoparticles. Journal of Physics: Conference Series 170, pages 012038.
Crossref
Robert Landsiedel, Eric Fabian, Lan Ma-Hock, Karin Wiench & Bennard van Ravenzwaay. (2009) Biokinetics and effects of titania nano-material after inhalation and i.v. injection . Journal of Physics: Conference Series 170, pages 012017.
Crossref

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