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Original Article

Radiation-induced Genomic Instability: Delayed Cytogenetic Aberrations and Apoptosis in Primary Human Bone Marrow Cells

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Pages 287-293 | Received 26 Sep 1994, Accepted 16 Nov 1994, Published online: 03 Jul 2009

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V.W.Y. Choi & K.N. Yu. (2015) Embryos of the zebrafish Danio rerio in studies of non-targeted effects of ionizing radiation. Cancer Letters 356:1, pages 91-104.
Crossref
Elaine Ron & Jay H. Lubin. 2014. Wiley StatsRef: Statistics Reference Online. Wiley StatsRef: Statistics Reference Online.
Arcadi Cipponi & David M. Thomas. (2014) Stress-induced cellular adaptive strategies: Ancient evolutionarily conserved programs as new anticancer therapeutic targets. BioEssays 36:6, pages 552-560.
Crossref
Antone L. Brooks & Lawrence T. Dauer. (2014) Advances in Radiation Biology: Effect on Nuclear Medicine. Seminars in Nuclear Medicine 44:3, pages 179-186.
Crossref
K.M. Prise & G. Schettino. 2014. Comprehensive Biomedical Physics. Comprehensive Biomedical Physics 23 42 .
Kanokporn Noy Rithidech, Louise M. Honikel, Paiboon Reungpatthanaphong, Montree Tungjai, Marc Golightly & Elbert B. Whorton. (2013) Effects of 100 MeV protons delivered at 0.5 or 1 cGy/min on the in vivo induction of early and delayed chromosomal damage. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 756:1-2, pages 127-140.
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Kanokporn Rithidech, Chatchanok Udomtanakunchai, Louise Honikel & Elbert Whorton. (2013) Response to Baverstock, K. Comments on Rithidech, K.N.; et al. Lack of Genomic Instability in Bone Marrow Cells of SCID Mice Exposed Whole-Body to Low-Dose Radiation. Int. J. Environ. Res. Public Health 2013, 10, 1356–1377.. International Journal of Environmental Research and Public Health 10:7, pages 2735-2740.
Crossref
Kanokporn Rithidech, Chatchanok Udomtanakunchai, Louise Honikel & Elbert Whorton. (2013) Lack of Genomic Instability in Bone Marrow Cells of SCID Mice Exposed Whole-Body to Low-Dose Radiation. International Journal of Environmental Research and Public Health 10:4, pages 1356-1377.
Crossref
Carmel MotherSill & Colin Seymour. (2012) Changing paradigms in radiobiology. Mutation Research/Reviews in Mutation Research 750:2, pages 85-95.
Crossref
Kanokporn Noy Rithidech, Chatchanok Udomtanakunchai, Louise M. Honikel & Elbert B. Whorton. (2011) No Evidence for the in vivo Induction of Genomic Instability by Low Doses of 137 Cs Gamma Rays in Bone Marrow Cells of BALB/cJ and C57BL/6J Mice . Dose-Response 10:1, pages dose-response.1.
Crossref
Kevin M. Prise & Giuseppe Schettino. 2012. Radiation Damage in Biomolecular Systems. Radiation Damage in Biomolecular Systems 385 396 .
L. A. Braby, A. L. Brooks, W. F. Heidenreich, M. A. Hill, R. W. Howell, K. Kobayashi, W. E. Wilson & M. Zaider. (2011) References. Journal of the ICRU 11:2, pages 69-77.
Crossref
Mary Helen Barcellos-Hoff & David H. Nguyen. 2011. Tumor-Associated Fibroblasts and their Matrix. Tumor-Associated Fibroblasts and their Matrix 267 282 .
David H. Nguyen, Irineu Illa Bochaca & Mary Helen Barcellos-Hoff. 2011. Environment and Breast Cancer. Environment and Breast Cancer 185 203 .
Kevin Prise & Giuseppe Schettino. 2010. Charged Particle and Photon Interactions with Matter. Charged Particle and Photon Interactions with Matter 575 594 .
Mary Helen Barcellos-Hoff. (2010) Stromal Mediation of Radiation Carcinogenesis. Journal of Mammary Gland Biology and Neoplasia 15:4, pages 381-387.
Crossref
Jaroslaw Dziegielewski, Wilfried Goetz & Janet E. Baulch. (2009) Heavy ions, radioprotectors and genomic instability: implications for human space exploration. Radiation and Environmental Biophysics 49:3, pages 303-316.
Crossref
Munira A. Kadhim, Ryonfa Lee, Stephen R. Moore, Denise A. Macdonald, Kim L. Chapman, Gaurang Patel & Kevin M. Prise. (2010) Genomic instability after targeted irradiation of human lymphocytes: Evidence for inter-individual differences under bystander conditions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 688:1-2, pages 91-94.
Crossref
Mary Helen Barcellos-Hoff & David H. Nguyen. (2009) RADIATION CARCINOGENESIS IN CONTEXT: HOW DO IRRADIATED TISSUES BECOME TUMORS?. Health Physics 97:5, pages 446-457.
Crossref
Yoon Hee Cho, Yang Jee Kim, You Sun An, Hae Dong Woo, Soo Yong Choi, Chang Mo Kang & Hai Won Chung. (2009) Micronucleus-centromere assay and DNA repair gene polymorphism in lymphocytes of industrial radiographers. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 680:1-2, pages 17-24.
Crossref
Kanokporn Noy Rithidech, Wisa Supanpaiboon, Louise Honikel & Elbert B. Whorton. (2009) Induction of genomic instability after an acute whole-body exposure of mice to 56Fe ions. Advances in Space Research 44:8, pages 895-906.
Crossref
K. Hamasaki, Y. Kusunoki, E. Nakashima, N. Takahashi, K. Nakachi, N. Nakamura & Y. Kodama. (2009) Clonally Expanded T Lymphocytes from Atomic Bomb Survivors In Vitro Show No Evidence of Cytogenetic Instability . Radiation Research 172:2, pages 234-243.
Crossref
Ernst Schmid & H. Roos. (2008) Influence of the bystander phenomenon on the chromosome aberration pattern in human lymphocytes induced by in vitro α-particle exposure. Radiation and Environmental Biophysics 48:2, pages 181-187.
Crossref
Christopher A. Maxwell, Markus C. Fleisch, Sylvain V. Costes, Anna C. Erickson, Arnaud Boissière, Rishi Gupta, Shraddha A. Ravani, Bahram Parvin & Mary Helen Barcellos-Hoff. (2008) Targeted and Nontargeted Effects of Ionizing Radiation That Impact Genomic Instability. Cancer Research 68:20, pages 8304-8311.
Crossref
Viktor Janzen, Heather E. Fleming, Tamara Riedt, Göran Karlsson, Matthew J. Riese, Cristina Lo Celso, Griffin Reynolds, Craig D. Milne, Christopher J. Paige, Stefan Karlsson, Minna Woo & David T. Scadden. (2008) Hematopoietic Stem Cell Responsiveness to Exogenous Signals Is Limited by Caspase-3. Cell Stem Cell 2:6, pages 584-594.
Crossref
Rosalie Bertell, Lynn Howard Ehrle & Inge Schmitz-Feuerhake. (2016) Pediatric CT Research Elevates Public Health Concerns: Low-Dose Radiation Issues are Highly Politicized. International Journal of Health Services 37:3, pages 419-439.
Crossref
William F. Morgan & Marianne B. Sowa. (2007) Towards resolving conflicting reports of radiation-induced genomic instability in populations exposed to ionizing radiation: Implications for the hibakusha. International Congress Series 1299, pages 128-134.
Crossref
Ruth C. Barber & Yuri E. Dubrova. (2006) The offspring of irradiated parents, are they stable?. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 598:1-2, pages 50-60.
Crossref
Sahana Kaup, Valerie Grandjean, Rajarshi Mukherjee, Aparna Kapoor, Edward Keyes, Colin B. Seymour, Carmel E. Mothersill & Paul N. Schofield. (2006) Radiation-induced genomic instability is associated with DNA methylation changes in cultured human keratinocytes. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 597:1-2, pages 87-97.
Crossref
Deborah A. Bowler, Stephen R. Moore, Denise A. Macdonald, Sharon H. Smyth, Peter Clapham & Munira A. Kadhim. (2006) Bystander-mediated genomic instability after high LET radiation in murine primary haemopoietic stem cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 597:1-2, pages 50-61.
Crossref
Eric G Wright & Philip J Coates. (2006) Untargeted effects of ionizing radiation: Implications for radiation pathology. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 597:1-2, pages 119-132.
Crossref
R.G. Ahmed. (2006) Damage Pattern as a Function of Various Types of Radiation. International Journal of Zoological Research 2:2, pages 150-168.
Crossref
N. Taibi, P. Aka, M. Kirsch-Volders, P. Bourgeois, J. Frühling & C. Szpireer. (2006) Radiobiological effect of 99mTechnetium-MIBI in human peripheral blood lymphocytes: Ex vivo study using micronucleus/FISH assay. Cancer Letters 233:1, pages 68-78.
Crossref
J. Valentin. (2016) Chapters 6 and 7. Annals of the ICRP 35:4, pages 93-140.
Crossref
Keith Baverstock & Oleg V Belyakov. (2016) Classical radiation biology, the bystander effect and paradigms: a reply. Human & Experimental Toxicology 24:10, pages 537-542.
Crossref
Elaine Ron & Jay H. Lubin. 2005. Encyclopedia of Biostatistics. Encyclopedia of Biostatistics.
C Mothersill, M J Moriarty & C B Seymour. (2005) Bystander and other delayed effects and multi-organ involvement and failure following high dose exposure to ionising radiation. The British Journal of Radiology Supplement_27:1, pages 128-131.
Crossref
Punnajit Pongsaensook, Linda E. Ritter, Karyn K. Parks & Andrew J. Grosovsky. (2004) Cis-acting transmission of genomic instability. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 568:1, pages 49-68.
Crossref
Philip J. Coates, Sally A. Lorimore & Eric G. Wright. (2004) Damaging and protective cell signalling in the untargeted effects of ionizing radiation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 568:1, pages 5-20.
Crossref
Paula V Bennett, Nela S Cintron, Laurent Gros, Jacques Laval & Betsy M Sutherland. (2004) Are endogenous clustered dna damages induced in human cells?. Free Radical Biology and Medicine 37:4, pages 488-499.
Crossref
Yingsong Xiang, Suping Sun, Jianming Cai, Mingfeng Xiang, Gusheng Tang & Xuetao Cao. (2004) ENHANCEMENT OF FRACTIONATED BONE MARROW TRANSPLANTATION ON HEMATOPOIETIC CELL HOMING IN A MOUSE ALLOGENEIC MODEL1. Transplantation 77:7, pages 972-978.
Crossref
Aimin Meng, Yong Wang, Stephen A Brown, Gary Van Zant & Daohong Zhou. (2003) Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and -independent mechanisms. Experimental Hematology 31:12, pages 1348-1356.
Crossref
Antone L. Brooks. (2003) Developing a scientific basis for radiation risk estimates: major goal of the DOE Low Dose Radiation Research Program. International Congress Series 1258, pages 287-295.
Crossref
Zelanna Goldberg. (2003) Clinical implications of radiation-induced genomic instability. Oncogene 22:45, pages 7011-7017.
Crossref
John B Little. (2003) Genomic instability and bystander effects: a historical perspective. Oncogene 22:45, pages 6978-6987.
Crossref
Munira A Kadhim. (2003) Role of genetic background in induced instability. Oncogene 22:45, pages 6994-6999.
Crossref
Catherine C. Park, Rhonda L. Henshall-Powell, Anna C. Erickson, Rabih Talhouk, Bahram Parvin, Mina J. Bissell & Mary Helen Barcellos-Hoff. (2003) Ionizing radiation induces heritable disruption of epithelial cell interactions. Proceedings of the National Academy of Sciences 100:19, pages 10728-10733.
Crossref
Antone L. Brooks. (2003) DEVELOPING A SCIENTIFIC BASIS FOR RADIATION RISK ESTIMATES: GOAL OF THE DOE LOW DOSE RESEARCH PROGRAM. Health Physics 85:1, pages 85-93.
Crossref
Leslie E. Smith, Shruti Nagar, Grace J. Kim & William F. Morgan. (2003) RADIATION-INDUCED GENOMIC INSTABILITY: RADIATION QUALITY AND DOSE RESPONSE. Health Physics 85:1, pages 23-29.
Crossref
Helen H. Evans, Min-Fen Horng, Marlene Ricanati, M. Diaz-Insua, Robert Jordan & Jeffrey L. Schwartz. (2003) Induction of Genomic Instability in TK6 Human Lymphoblasts Exposed to 137 Cs γ Radiation: Comparison to the Induction by Exposure to Accelerated 56 Fe Particles . Radiation Research 159:6, pages 737-747.
Crossref
Carmel Mothersill & Colin Seymour. (2003) Low-dose radiation effects: Experimental hematology and the changing paradigm. Experimental Hematology 31:6, pages 437-445.
Crossref
Michael Kilemade & Carmel Mothersill. (2003) Expression of delayed cell death (DCD) in the progeny of fish cells surviving 2,4-dichloroaniline (2,4-DCA) exposure. Aquatic Toxicology 63:3, pages 207-219.
Crossref
N Coen, M A Kadhim, E G Wright, C P Case & C E Mothersill. (2003) Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells. British Journal of Cancer 88:4, pages 548-552.
Crossref
Harry Rubin. 2003. 1 62 .
Helen H. Evans, Min-Fen Horng, Marlene Ricanati, Mireya Diaz-Insua, Robert Jordan & Jeffrey L. Schwartz. (2002) Characteristics of Genomic Instability in Clones of TK6 Human Lymphoblasts Surviving Exposure to 56 Fe Ions . Radiation Research 158:6, pages 687-698.
Crossref
Joel S. Bedford & William C. Dewey. (2002) Historical and Current Highlights in Radiation Biology: Has Anything Important Been Learned by Irradiating Cells?. Radiation Research 158:3, pages 251-291.
Crossref
E.G Wright. (2002) The responses of the haemopoietic system to ionizing radiation. International Congress Series 1236, pages 271-281.
Crossref
Rhonda L Henshall-Powell, Catherine C Park & Mary Helen Barcellos-Hoff. (2002) Aberrant extracellular signaling induced by ionizing radiation and its role in carcinogenesis. International Congress Series 1236, pages 399-405.
Crossref
Nigel E.A. Crompton, Yu-Quan Shi, Frederich Wuergler & Hans Blattmann. (2002) A single low dose of X-rays induces high frequencies of genetic instability (aneuploidy) and heritable damage (apoptosis), dependent on cell type and p53 status. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 517:1-2, pages 173-186.
Crossref
F. M. Lyng, C. B. Seymour & C. Mothersill. (2002) Initiation of Apoptosis in Cells Exposed to Medium from the Progeny of Irradiated Cells: A Possible Mechanism for Bystander-Induced Genomic Instability?. Radiation Research 157:4, pages 365-370.
Crossref
B.I. Lord & L.B. Woolford. (2002) Induction of stem cell cycling in mice increases their sensitivity to a chemical leukaemogen: implications for inherited genomic instability and the bystander effect. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 501:1-2, pages 13-17.
Crossref
Zdenek Smerhovsky, Karel Landa, Pavel Rőssner, Dagmar Juzova, Marek Brabec, Zdena Zudova, Nora Hola, Hana Zarska & Emilie Nevsimalova. (2002) Increased risk of cancer in radon-exposed miners with elevated frequency of chromosomal aberrations. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 514:1-2, pages 165-176.
Crossref
BETSY M. SUTHERLAND, PAULA V. BENNETT, NELA CINTRON-TORRES, MEGUMI HADA, JOHN TRUNK, DENISE MONTELEONE, JOHN C. SUTHERLAND, JACQUES LAVAL, MARISHA STANISLAUS & ALAN GEWIRTZ. (2002) Clustered DNA Damages Induced in Human Hematopoietic Cells by Low Doses of Ionizing Radiation. Journal of Radiation Research 43:S, pages S149-S152.
Crossref
C. A. Whitehouse & E. J. Tawn. (2001) No Evidence for Chromosomal Instability in Radiation Workers with In Vivo Exposure to Plutonium . Radiation Research 156:5, pages 467-475.
Crossref
Natasha Coen, Carmel Mothersill, Munira Kadhim & E. G. Wright. (2001) Heavy metals of relevance to human health induce genomic instability. The Journal of Pathology 195:3, pages 293-299.
Crossref
H. H. Evans, M. F. Horng, M. Ricanati, M. Diaz-Insua, R. Jordan & J. L. Schwartz. (2001) Diverse Delayed Effects in Human Lymphoblastoid Cells Surviving Exposure to High-LET 56 Fe Particles or Low-LET 137 Cs Gamma Radiation . Radiation Research 156:3, pages 259-271.
Crossref
Harriet Phillips & Douglas Chambers. 2001. Medical Management of Radiation Accidents, Second Edition. Medical Management of Radiation Accidents, Second Edition 507 518 .
Phil S. Hartman, Anthony Hlavacek, Honor Wilde, Dan Lewicki, Wayne Schubert, Roger G. Kern, Gayane A. Kazarians, Eugene V. Benton, Eric R. Benton & Gregory A. Nelson. (2001) A comparison of mutations induced by accelerated iron particles versus those induced by low earth orbit space radiation in the FEM-3 gene of Caenorhabditis elegans. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 474:1-2, pages 47-55.
Crossref
M. A. Kadhim, S. J. Marsden, A. M. Malcolmson, M. Folkard, D. T. Goodhead, K. M. Prise & B. D. Michael. (2001) Long-Term Genomic Instability in Human Lymphocytes Induced by Single-Particle Irradiation. Radiation Research 155:1, pages 122-126.
Crossref
Mitchell S Turker. (2000) Somatic cell mutations: can they provide a link between aging and cancer?. Mechanisms of Ageing and Development 117:1-3, pages 1-19.
Crossref
Lidia Mazur. (2000) Radioprotective effects of the thiols GSH and WR-2721 against X-ray-induction of micronuclei in erythroblasts. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 468:1, pages 27-33.
Crossref
F.A Cucinotta, J.W Wilson, J.R Williams & J.F Dicello. (2000) Analysis of MIR-18 results for physical and biological dosimetry: radiation shielding effectiveness in LEO. Radiation Measurements 32:3, pages 181-191.
Crossref
Z. Somosy. (2000) Radiation response of cell organelles. Micron 31:2, pages 165-181.
Crossref
Douglas Holdstock & Lis Waterston. (2000) Nuclear weapons, a continuing threat to health. The Lancet 355:9214, pages 1544-1547.
Crossref
John B. Little. (2000) Radiation carcinogenesis. Carcinogenesis 21:3, pages 397-404.
Crossref
Polly Y Chang, Dorothea Torous, Louise Lutze-Mann & Richard Winegar. (2000) Impact of p53 status on heavy-ion radiation-induced micronuclei in circulating erythrocytes. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466:1, pages 87-96.
Crossref
C.L. Limoli, B. Ponnaiya, J.J. Corcoran, E. Giedzinski, M.I. Kaplan, A. Hartmann & W.F. Morgan. (2000) Genomic instability induced by high and low let ionizing radiation. Advances in Space Research 25:10, pages 2107-2117.
Crossref
Carmel E. Mothersill, Kiaran J. O'Malley, Dennis M. Murphy, Colin B. Seymour, Sally A. Lorimore & Eric G. Wright. (1999) Identification and characterization of three subtypes of radiation response in normal human urothelial cultures exposed to ionizing radiation. Carcinogenesis 20:12, pages 2273-2278.
Crossref
I Testard & L Sabatier. (1999) Biological dosimetry for astronauts: a real challenge. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 430:2, pages 315-326.
Crossref
Wushou P. Chang, Yi‐ping Lin, Pai‐tsang Hwang, Jih‐Luh Tang, Jer‐yuan D. Chen & Shy‐Dye Lee. (2001) Persistent leucocyte abnormalities in children years after previous long‐term low‐dose radiation exposure. British Journal of Haematology 106:4, pages 954-959.
Crossref
KANAKLATA ROY, SEIJI KODAMA, KEIJI SUZUKI & MASAMI WATANABE. (1999) Delayed Cell Death, Giant Cell Formation and Chromosome Instability Induced by X-irradiation in Human Embryo Cells. Journal of Radiation Research 40:4, pages 311-322.
Crossref
Margaret M. Lehane, Peter E. Bryant, Andrew C. Riches, Louise A. Allen, Cecilie V. Briscoe, Jean Melville & Andrew J. Mill. (1999) 238Pu α-particle-induced C3H10T½ transformants are less tumorigenic than the X-ray-induced equivalent. Carcinogenesis 20:1, pages 35-40.
Crossref
Eric G. Wright. (1999) Inherited and inducible chromosomal instability: a fragile bridge between genome integrity mechanisms and tumourigenesis. The Journal of Pathology 187:1, pages 19-27.
Crossref
Isabelle Testard & Laure Sabatier. (1998) Is delayed genomic instability specifically induced by high-LET particles?. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 146:1-4, pages 518-527.
Crossref
Mats Harms-Ringdahl. (1998) Some aspects on radiation induced transmissible genomic instability. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 404:1-2, pages 27-33.
Crossref
Charles L. Limoli, Joseph P. Day, John F. Ward & William F. Morgan. (2008) Induction of Chromosome Aberrations and Delayed Genomic Instability by Photochemical Processes. Photochemistry and Photobiology 67:2, pages 233-238.
Crossref
Yuri E. Nikiforov & James A. Fagin. 1998. 169 196 .
S Yamada, T.C Yang, K George, R Okayasu, K Ando & H Tsujii. (1998) Microsatellite instability in human mammary epithelial cells transformed by heavy ions. Advances in Space Research 22:12, pages 1709-1717.
Crossref
M.A Kadhim & E.G Wright. (1998) Radiation-induced transmissable chromosomal instability in haemopoietic stem cells. Advances in Space Research 22:4, pages 587-596.
Crossref
Toshihiko Ozawa, Kouichi Tatsumi & Tada-aki HoriAkiko Ueno, Diane Vannais, Megan McGraw, Russell Drabek, Daniel Gustafson, Jeanie Robinson & Charles Waldren. 1998. Biodefence Mechanisms Against Environmental Stress. Biodefence Mechanisms Against Environmental Stress 145 150 .
Ann C. Williams, Jayne C. Miller, Tracey Collard, Sara J. Browne, Robert F. Newbold & Christos Paraskeva. (1997) The effect of differentTP53 mutations on the chromosomal stability of a human colonic adenoma derived cell line with endogenous wild type TP53 activity, before and after DNA damage. Genes, Chromosomes and Cancer 20:1, pages 44-52.
Crossref
C. Mothersill, K. O'Malley, D. Murphy & C.B. Seymour. (1997) Apoptosis and other effects of radiation in normal human urothelial cells. Radiation Oncology Investigations 5:3, pages 150-153.
Crossref
Rosemary M. Caron, Hatsumi Nagasawa, Yongjia Yu, Tracy Pfenning, Helen Vetrovs & John B. Little. (1997) Evidence for a role for genomic instability in radiation-induced mutagenesis. Radiation Oncology Investigations 5:3, pages 119-123.
Crossref
Eric G. Wright. (1997) Radiation-induced genomic instability in haemopoietic cells:Implications for radiation pathology. Radiation Oncology Investigations 5:3, pages 115-118.
Crossref
C.B. Seymour & C. Mothersill. (1997) Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment. Radiation Oncology Investigations 5:3, pages 106-110.
Crossref
John P. Murname. (1996) Role of induced genetic instability in the mutagenic effects of chemicals and radiation. Mutation Research/Genetic Toxicology 367:1, pages 11-23.
Crossref

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