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Original Articles

Black Pepper and Health Claims: A Comprehensive Treatise

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Pages 875-886 | Published online: 14 Jun 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Moumita Nath & Pradip Debnath. (2023) Therapeutic role of traditionally used Indian medicinal plants and spices in combating COVID-19 pandemic situation. Journal of Biomolecular Structure and Dynamics 41:12, pages 5894-5913.
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Oluwaseun Hannah Ademuyiwa, Beatrice Mofoluwaso Fasogbon & Oluwafemi Ayodeji Adebo. (2023) The potential role of Piper guineense (black pepper) in managing geriatric brain aging: a review. Critical Reviews in Food Science and Nutrition 63:16, pages 2840-2850.
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Jirakrit Saetang, Aman Tedasen, Surasak Sangkhathat, Natnaree Sangkaew, Sirinapa Dokduang, Napat Prompat, Siriporn Taraporn & Potchanapond Graidist. (2022) The attenuation effect of low piperine Piper nigrum extract on doxorubicin-induced toxicity of blood chemical and immunological properties in mammary tumour rats. Pharmaceutical Biology 60:1, pages 96-107.
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Ayhan Vurmaz, Reşat Duman, Mehmet Cem Sabaner, Tolga Ertekin & Abdülkadir Bilir. (2019) Antioxidant effects of piperine in in-vivo chick embryo cataract model induced by steroids. Cutaneous and Ocular Toxicology 38:2, pages 182-189.
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Tianjing Ren, Qianwen Wang, Chenrui Li, Mengbi Yang & Zhong Zuo. (2018) Efficient brain uptake of piperine and its pharmacokinetics characterization after oral administration. Xenobiotica 48:12, pages 1249-1257.
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Giulia Gigliarelli, Rita Pagiotti, Diana Persia & Maria Carla Marcotullio. (2017) Optimisation of a Naviglio-assisted extraction followed by determination of piperine content in Piper longum extracts. Natural Product Research 31:2, pages 214-217.
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D. Chavarria, T. Silva, D. Magalhães e Silva, F. Remião & F. Borges. (2016) Lessons from black pepper: piperine and derivatives thereof. Expert Opinion on Therapeutic Patents 26:2, pages 245-264.
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BrahmaNaidu Parim, Nemani Harishankar, Meriga Balaji, Sailaja Pothana & Ramgopal Rao Sajjalaguddam. (2015) Effects of Piper nigrum extracts: Restorative perspectives of high-fat diet-induced changes on lipid profile, body composition, and hormones in Sprague–Dawley rats. Pharmaceutical Biology 53:9, pages 1318-1328.
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Articles from other publishers (85)

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Sheel Yadav, Anshika Tyagi, Ratna Kumari, Harsha Srivastava, Parimalan Rangan, Dhammaprakash Wankhede & Ambika B Gaikwad. (2023) Comparative transcriptome profiling of fruit tissue provides novel insights into piperine biosynthesis in black pepper (Piper nigrum L.). Scientia Horticulturae 322, pages 112451.
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Sanchit Arora, Baljinder Singh, Sandeep Kumar, Arun Kumar, Arti Singh & Charan Singh. (2023) Piperine loaded drug delivery systems for improved biomedical applications: Current status and future directions. Health Sciences Review 9, pages 100138.
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Chinedu C. Obieze, Paul B.L. George, Brian Boyle & Damase P. Khasa. (2023) Black pepper pathogen suppression: Divergent rhizosphere fungal communities of healthy and diseased plants yield new insights for orchard management in Vietnam. Fungal Ecology 66, pages 101295.
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Mengying Zhang, Beibei Qiu, Mengjia Sun, Yunfei Wang, Meijiao Wei, Yanling Gong & Meixing Yan. (2022) Preparation of Black pepper (Piper nigrum L.) essential oil nanoparticles and its antitumor activity on triple negative breast cancer in vitro . Journal of Food Biochemistry 46:12.
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Xiong Wang, Yanhua Zhang, Lei Zhang, Wenli Wang, Huilian Che & Yali Zhang. (2022) Piperine attenuates hepatic steatosis and insulin resistance in high-fat diet-induced obesity in Sprague-Dawley rats. Nutrition Research 108, pages 9-21.
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Asli Can Karaca. (2019) Encapsulation of black pepper seed oil using maltodextrin and pea protein. Food Science and Technology International 26:5, pages 369-378.
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Rathapon Asasutjarit, Papawee Sookdee, Sukitaya Veeranondha, Asira Fuongfuchat & Arunporn Itharat. (2020) Application of film-forming solution as a transdermal delivery system of piperine-rich herbal mixture extract for anti-inflammation. Heliyon 6:6, pages e04139.
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Ayhan VURMAZ, Fatih BOZKURT & Mine DOSAY AKBULUT. (2020) THE EFFECT OF BETAINE AND PIPERINE ON RATS WITH CREATED ALZHEIMER- LIKE DEMENTIA BY AF64AAF64A TARAFINDAN ALZHEİMER BENZERİ DEMANS OLUŞTURULAN RATLARDA BETAİN ve PİPERİNİN ETKİSİ. Kocatepe Tıp Dergisi 21:2, pages 183-190.
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Thi Tho Bui, Yanjing Fan, Chun Hua Piao, Thi Van Nguyen, Dong-uk Shin, Sun Young Jung, Eunjin Hyeon, Chang Ho Song, So-Young Lee, Hee Soon Shin & Ok Hee Chai. (2020) Piper Nigrum extract improves OVA-induced nasal epithelial barrier dysfunction via activating Nrf2/HO-1 signaling. Cellular Immunology 351, pages 104035.
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Erizal Zaini, Afriyani, Lili Fitriani, Friardi Ismed, Ayano Horikawa & Hidehiro Uekusa. (2020) Improved Solubility and Dissolution Rates in Novel Multicomponent Crystals of Piperine with Succinic Acid. Scientia Pharmaceutica 88:2, pages 21.
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Truong Dam Thai Vinh, Ly Thi Minh Hien & Dong Thi Anh Dao. (2020) Formulation of black pepper ( Piper nigrum L.) essential oil nano‐emulsion via phase inversion temperature method . Food Science & Nutrition 8:4, pages 1741-1752.
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Ruchita Tyagi, Vivek Gupta, Rajiv Kumar & GS Wander. (2020) Traditional Indian practices: Time to revisit and re-adopt for a healthier lifestyle. Journal of Anaesthesiology Clinical Pharmacology 36:5, pages 166.
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Federica Geddo, Rosaria Scandiffio, Susanna Antoniotti, Erika Cottone, Giulia Querio, Massimo E. Maffei, Patrizia Bovolin & Maria Pia Gallo. (2019) PipeNig®-FL, a Fluid Extract of Black Pepper (Piper Nigrum L.) with a High Standardized Content of Trans-β-Caryophyllene, Reduces Lipid Accumulation in 3T3-L1 Preadipocytes and Improves Glucose Uptake in C2C12 Myotubes. Nutrients 11:11, pages 2788.
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Clémentine M.G. Charoux, Colm P. O'Donnell & Brijesh K. Tiwari. (2019) Effect of airborne ultrasonic technology on microbial inactivation and quality of dried food ingredients. Ultrasonics Sonochemistry 56, pages 313-317.
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Jing-Ya Yang, Jing Zhang & Gang Zhou. (2018) Black pepper and its bioactive constituent piperine: promising therapeutic strategies for oral lichen planus. Inflammopharmacology 27:1, pages 5-13.
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Wenxue Chen, Hui Tang, Ningxin Jiang, Qiuping Zhong, Yueying Hu, Haiming Chen & Weijun Chen. (2019) Antibacterial Effect of Black Pepper Petroleum Ether Extract against Listeria monocytogenes and Salmonella typhimurium . Journal of Food Quality 2019, pages 1-10.
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Thi Tho Bui, Chun Hua Piao, Eunjin Hyeon, Yanjing Fan, Thi Van Nguyen, Sun Young Jung, Dae Woon Choi, So-young Lee, Hee Soon Shin, Chang Ho Song & Ok Hee Chai. (2019) The protective role of Piper nigrum fruit extract in an ovalbumin-induced allergic rhinitis by targeting of NFκBp65 and STAT3 signalings. Biomedicine & Pharmacotherapy 109, pages 1915-1923.
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Adrian L. Lopresti, Hemant Gupta & Stephen J. Smith. (2018) A poly-herbal blend (Herbagut®) on adults presenting with gastrointestinal complaints: a randomised, double-blind, placebo-controlled study. BMC Complementary and Alternative Medicine 18:1.
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Yimin Zhao, Jianhui Liu, Wangjun Hao, Zouyan He, Hanyue Zhu, Ning Liang, Ka Ying Ma, Wen-Sen He, Yan Yang & Zhen-Yu Chen. (2018) Plasma cholesterol-lowering activity of piperine is mediated by inhibition on cholesterol absorption via down-regulation of intestinal ACAT2 and MTP. Journal of Functional Foods 49, pages 465-471.
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Yimin Zhao & Zhen-Yu Chen. (2018) Roles of Spicy Foods and Their Bioactive Compounds in Management of Hypercholesterolemia. Journal of Agricultural and Food Chemistry 66:33, pages 8662-8671.
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Hong Liu, Jie Zheng, Pengzhan Liu & Fankui Zeng. (2018) Pulverizing processes affect the chemical quality and thermal property of black, white, and green pepper (Piper nigrum L.). Journal of Food Science and Technology 55:6, pages 2130-2142.
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Biswajit Mohanty, Ambigapathy Suvitha & Natarajan Sathiyamoorthy Venkataramanan. (2018) Piperine Encapsulation within Cucurbit[ n ]uril ( n =6,7): A Combined Experimental and Density Functional Study . ChemistrySelect 3:6, pages 1933-1941.
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Inés Reynoso-Moreno, Israel Najar-Guerrero, Noé Escareño, Mario Eduardo Flores-Soto, Jürg Gertsch & Juan Manuel Viveros-Paredes. (2017) An Endocannabinoid Uptake Inhibitor from Black Pepper Exerts Pronounced Anti-Inflammatory Effects in Mice. Journal of Agricultural and Food Chemistry 65:43, pages 9435-9442.
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Soňa Škrovánková, Jiří­ Mlček, Jana Orsavová, Tűnde Jurí­ková & Pavla Dří­malová. (2017) Polyphenols content and antioxidant activity of paprika and pepper spices. Potravinarstvo Slovak Journal of Food Sciences 11:1, pages 52-57.
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P. Haris, Varughese Mary, M. Haridas & C. Sudarsanakumar. (2015) Energetics, Thermodynamics, and Molecular Recognition of Piperine with DNA. Journal of Chemical Information and Modeling 55:12, pages 2644-2656.
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Abdul Rehman, Malik Hassan Mehmood, Muhammad Haneef, Anwarul Hassan Gilani, Maimoona Ilyas, Bina Shaheen Siddiqui & Mansoor Ahmed. (2015) Potential of black pepper as a functional food for treatment of airways disorders. Journal of Functional Foods 19, pages 126-140.
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Yeo Cho Yoon, Sung-Hee Kim, Min Jung Kim, Hye Jeong Yang, Mee-Ra Rhyu & Jae-Ho Park. (2014) Piperine, a component of black pepper, decreases eugenol‐induced cAMP and calcium levels in non‐chemosensory 3T3‐L1 cells. FEBS Open Bio 5:1, pages 20-25.
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Parim BrahmaNaidu, Harishankar Nemani, Balaji Meriga, Santosh Kumar Mehar, Sailaja Potana & Sajjalaguddam Ramgopalrao. (2014) Mitigating efficacy of piperine in the physiological derangements of high fat diet induced obesity in Sprague Dawley rats. Chemico-Biological Interactions 221, pages 42-51.
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