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Original Articles

Dietary flavonoid aglycones and their glycosides: Which show better biological significance?

Keep up to date with the latest research on this topic with citation updates for this article.

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Fatchiyah Fatchiyah, Anna Safitri, Christine Natalia Palis, Dewi Ratih Tirto Sari, Eko Suyanto, Sisca Fajriani, Nia Kurnianingsih, Yudhistira Nugraha, Trias Sitaresmi, Bram Kusbiantoro & James Robert Ketudat-Cairns. (2023) Bioactive compound profile and their biological activities of endogenous black rice from Java and East Nusa Tenggara. CyTA - Journal of Food 21:1, pages 159-170.
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Changhong Li, Taotao Dai, Jun Chen, Mingshun Chen, Ruihong Liang, Chengmei Liu, Liqing Du & David Julian McClements. (2023) Modification of flavonoids: methods and influences on biological activities. Critical Reviews in Food Science and Nutrition 63:31, pages 10637-10658.
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Tiantian Tian, Hui Cao, Mohamed A. Farag, Siting Fan, Luxuan Liu, Wenjing Yang, Yuxuan Wang, Liang Zou, Ka-Wing Cheng, Mingfu Wang, Xiaolei Ze, Jesus Simal-Gandara, Chao Yang & Zhiwei Qin. (2023) Current and potential trends in the bioactive properties and health benefits of Prunus mume Sieb. Et Zucc: a comprehensive review for value maximization. Critical Reviews in Food Science and Nutrition 63:24, pages 7091-7107.
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Xiaodan Li, Xiangfeng Meng, Tijn C. de Leeuw, Evelien M. te Poele, Tjaard Pijning, Lubbert Dijkhuizen & Weifeng Liu. (2023) Enzymatic glucosylation of polyphenols using glucansucrases and branching sucrases of glycoside hydrolase family 70. Critical Reviews in Food Science and Nutrition 63:21, pages 5247-5267.
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Jiang Shi, Gaozhong Yang, Qiushuang You, Shili Sun, Ruohong Chen, Zhi Lin, Jesus Simal-Gandara & Haipeng Lv. (2023) Updates on the chemistry, processing characteristics, and utilization of tea flavonoids in last two decades (2001-2021). Critical Reviews in Food Science and Nutrition 63:20, pages 4757-4784.
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Hui Teng, Yimei Zheng, Hui Cao, Qun Huang, Jianbo Xiao & Lei Chen. (2023) Enhancement of bioavailability and bioactivity of diet-derived flavonoids by application of nanotechnology: a review. Critical Reviews in Food Science and Nutrition 63:3, pages 378-393.
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T. M. Cantero, P. I. Silva Junior, G. Negri, R. M. Nascimento & R. Z. Mendonça. (2023) Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica. Toxin Reviews 42:1, pages 300-315.
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Sunantha Ketnawa, Florencio Collado Reginio Jr.Sukanya Thuengtung & Yukiharu Ogawa. (2022) Changes in bioactive compounds and antioxidant activity of plant-based foods by gastrointestinal digestion: a review. Critical Reviews in Food Science and Nutrition 62:17, pages 4684-4705.
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Hassan Rasouli, Seyed Mohammad Bagher Hosseini Ghazvini, Reza Yarani, Ali Altıntaş, Saber Ghafari Nikoo Jooneghani & Teodorico C. Ramalho. (2022) Deciphering inhibitory activity of flavonoids against tau protein kinases: a coupled molecular docking and quantum chemical study. Journal of Biomolecular Structure and Dynamics 40:1, pages 411-424.
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E. J. Prpa, B. H. Bajka, P. R. Ellis, P. J. Butterworth, C. P. Corpe & W. L. Hall. (2021) A systematic review of in vitro studies evaluating the inhibitory effects of polyphenol-rich fruit extracts on carbohydrate digestive enzymes activity: a focus on culinary fruits consumed in Europe. Critical Reviews in Food Science and Nutrition 61:22, pages 3783-3803.
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Mahsa Sobhani, Mohammad Hosein Farzaei, Sarah Kiani & Reza Khodarahmi. (2021) Immunomodulatory; Anti-inflammatory/antioxidant Effects of Polyphenols: A Comparative Review on the Parental Compounds and Their Metabolites. Food Reviews International 37:8, pages 759-811.
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Mara Fiorani, Andrea Guidarelli & Orazio Cantoni. (2021) Mitochondrial reactive oxygen species: the effects of mitochondrial ascorbic acid vs untargeted and mitochondria-targeted antioxidants. International Journal of Radiation Biology 97:8, pages 1055-1062.
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Temine Sabudak, Hilmican Caliskan, H. Hulya Orak & Merve Ozer. (2021) Biological activity of new flavonoids and phenolic compounds from Cirsium italicum (Savi) DC.. Natural Product Research 35:10, pages 1613-1619.
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Dehai Xian, Menglu Guo, Jixiang Xu, Yang Yang, Yangmeng Zhao & Jianqiao Zhong. (2021) Current evidence to support the therapeutic potential of flavonoids in oxidative stress-related dermatoses. Redox Report 26:1, pages 134-146.
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S. Kavya Bhatt, R. Manjunatha Javagal, M. Shashirekha Nanjarajurs & Sachin M. Eligar. (2021) In vitro anti-inflammatory property of a Quercetin-3-O-diglucoside-7-O-glucoside characterized from fresh leaves of Trigonella foenum-graecum L. International Journal of Food Properties 24:1, pages 1438-1452.
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Haroon Khan, Hammad Ullah, Paula Cristina Machado Ferreira Castilho, Antoni Sureda Gomila, Grazia D'Onofrio, Rosanna Filosa, Fang Wang, Seyed Mohammad Nabavi, Maria Daglia, Ana Sanches Silva, Kannan R. R. Rengasamy, Juanying Ou, Xiaobo Zou, Jianbo Xiao & Hui Cao. (2020) Targeting NF-κB signaling pathway in cancer by dietary polyphenols. Critical Reviews in Food Science and Nutrition 60:16, pages 2790-2800.
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Elida Paula Dini de Franco, Fabiano Jares Contesini, Bianca Lima da Silva, Anna Maria Alves de Piloto Fernandes, Camila Wielewski Leme, João Pedro Gonçalves Cirino, Paula Renata Bueno Campos & Patrícia de Oliveira Carvalho. (2020) Enzyme-assisted modification of flavonoids from Matricaria chamomilla: antioxidant activity and inhibitory effect on digestive enzymes. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 42-49.
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Hui Cao, Juanying Ou, Lei Chen, Yanbo Zhang, Tomasz Szkudelski, Dominique Delmas, Maria Daglia & Jianbo Xiao. (2019) Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial. Critical Reviews in Food Science and Nutrition 59:20, pages 3371-3379.
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Zehua Yang, Fang Xiao, Yinxiang Zhang, Zaoduan Wu & Xing Zheng. (2019) Asymmetric Synthesis of Chiral Flavan-3-Ols. Natural Product Research 33:20, pages 2995-3010.
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Narges Cheshmazar, Siavoush Dastmalchi, Mineko Terao, Enrico Garattini & Maryam Hamzeh-Mivehroud. (2019) Aldehyde oxidase at the crossroad of metabolism and preclinical screening. Drug Metabolism Reviews 51:4, pages 428-452.
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Sui Kiat Chang, Cesarettin Alasalvar & Fereidoon Shahidi. (2019) Superfruits: Phytochemicals, antioxidant efficacies, and health effects – A comprehensive review. Critical Reviews in Food Science and Nutrition 59:10, pages 1580-1604.
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Jianbo Xiao & Weibin Bai. (2019) Bioactive phytochemicals. Critical Reviews in Food Science and Nutrition 59:6, pages 827-829.
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Chao Zhao, Chengfeng Yang, Sydney Tang Chi Wai, Yanbo Zhang, Maria P. Portillo, Paolo Paoli, Yijing Wu, Wai San Cheang, Bin Liu, Christian Carpéné, Jianbo Xiao & Hui Cao. (2019) Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus. Critical Reviews in Food Science and Nutrition 59:6, pages 830-847.
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Roodabeh Bahramsoltani, Farnaz Ebrahimi, Mohammad Hosein Farzaei, Armaghan Baratpourmoghaddam, Pardis Ahmadi, Pourouchista Rostamiasrabadi, Amir Hossein Rasouli Amirabadi & Roja Rahimi. (2019) Dietary polyphenols for atherosclerosis: A comprehensive review and future perspectives. Critical Reviews in Food Science and Nutrition 59:1, pages 114-132.
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Paola Hernández-Carranza, Karen Y. Jattar-Santiago, Raúl Avila-Sosa, Ivonne Pérez-Xochipa, José A. Guerrero-Beltrán, Carlos E. Ochoa-Velasco & Irving I. Ruiz-López. (2019) Antioxidant fortification of yogurt with red cactus pear peel and its mucilage. CyTA - Journal of Food 17:1, pages 824-833.
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Lei Chen, Hui Teng, Zhen Jia, Maurizio Battino, Anca Miron, Zhiling Yu, Hui Cao & Jianbo Xiao. (2018) Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence. Critical Reviews in Food Science and Nutrition 58:17, pages 2908-2924.
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Lei Chen, Hui Teng, Zhenglu Xie, Hui Cao, Wai San Cheang, Krystyna Skalicka-Woniak, Milen I. Georgiev & Jianbo Xiao. (2018) Modifications of dietary flavonoids towards improved bioactivity: An update on structure–activity relationship. Critical Reviews in Food Science and Nutrition 58:4, pages 513-527.
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Jianbo Xiao. (2016) Phytochemicals in Food and Nutrition. Critical Reviews in Food Science and Nutrition 56:sup1, pages S1-S3.
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Yingjun Liu, Qiuxia Yang, Yushan Guo, Yueming Jiang, Hong Zhu & Bao Yang. New insights of flavonoid glycosidases and their application in food industry. Critical Reviews in Food Science and Nutrition 0:0, pages 1-13.
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