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Articles

Nrf2 targeting by sulforaphane: A potential therapy for cancer treatment

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Xinhui Huang, Xinyu Zhou, Chunting Wu, Weiqi Li, Yongjie Ma, Qilian He & Fuli Ya. (2023) Sulforaphane attenuates platelet granule secretion through down-regulating glycoprotein VI-mediated p38 MAPK/cPLA2 signaling pathway. CyTA - Journal of Food 21:1, pages 189-197.
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Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar & Lauren C. Blekkenhorst. (2023) Sulfur compounds: From plants to humans and their role in chronic disease prevention. Critical Reviews in Food Science and Nutrition 63:27, pages 8616-8638.
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Amin Gasmi, Asma Gasmi Benahmed, Mariia Shanaida, Salvatore Chirumbolo, Alain Menzel, Wajiha Anzar, Mehreen Arshad, Natália Cruz-Martins, Roman Lysiuk, Nataliya Beley, Petro Oliinyk, Volodymyr Shanaida, Antonina Denys, Massimiliano Peana & Geir Bjørklund. (2023) Anticancer activity of broccoli, its organosulfur and polyphenolic compounds. Critical Reviews in Food Science and Nutrition 0:0, pages 1-19.
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Yang Ye, Ying Ma, Mei Kong, Zhihua Wang, Kang Sun & Fang Li. (2023) Effects of Dietary Phytochemicals on DNA Damage in Cancer Cells. Nutrition and Cancer 75:3, pages 761-775.
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Yang Zhang, Ping Ai, Shang-zhou Chen & Shu-ying Lei. (2023) Sulforaphane suppresses skin squamous cell carcinoma cells proliferation through miR-199a-5p/Sirt1/CD44ICD signaling pathway. Immunopharmacology and Immunotoxicology 45:1, pages 52-60.
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Hao-feng Gu, Xue-ying Mao & Min Du. (2022) Metabolism, absorption, and anti-cancer effects of sulforaphane: an update. Critical Reviews in Food Science and Nutrition 62:13, pages 3437-3452.
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Catarina Melim, Mariana Magalhães, Ana Cláudia Santos, Elisa Julião Campos & Célia Cabral. (2022) Nanoparticles as phytochemical carriers for cancer treatment: News of the last decade. Expert Opinion on Drug Delivery 19:2, pages 179-197.
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Nabila Jahan, Apu Chowdhury, Ting Li, Ke Xu, Fen Wei & Sicen Wang. (2021) Neferine improves oxidative stress and apoptosis in benign prostate hyperplasia via Nrf2-ARE pathway.. Redox Report 26:1, pages 1-9.
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Qi Xiong, Xiang Tian, Weiling Li, Lin Chen, Mei Zhou, Congyue Xu & Qin Ru. (2020) Sulforaphane alleviates methamphetamine-induced oxidative damage and apoptosis via the Nrf2-mediated pathway in vitro and in vivo. Food and Agricultural Immunology 31:1, pages 859-880.
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Matej Sova & Luciano Saso. (2018) Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review. Drug Design, Development and Therapy 12, pages 3181-3197.
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Elena Catanzaro, Cinzia Calcabrini, Eleonora Turrini, Piero Sestili & Carmela Fimognari. (2017) Nrf2: a potential therapeutic target for naturally occurring anticancer drugs?. Expert Opinion on Therapeutic Targets 21:8, pages 781-793.
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Articles from other publishers (102)

Jing Wen, Fan Yang, Cheng-xiang Fang, Hong-liu Chen & Li Yang. (2023) Sulforaphane triggers iron overload-mediated ferroptosis in gastric carcinoma cells by activating the PI3K/IRP2/DMT1 pathway. Human & Experimental Toxicology 42, pages 096032712311772.
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Guang Wang, Ran Zhao, Xinxia Zhang, Ying Zheng, Feiling Xie, Yu Jiang, Guohua Lv, Denglu Long, Chengyang Sun, Yongping Bao, Shuangyu Qi, Xinyue Liu, Qihao Zhang & Xuesong Yang. (2023) EGFR/MAPK signaling pathway acts as a potential therapeutic target for sulforaphane-rescued heart tube malformation induced by various concentrations of PhIP exposure. Phytomedicine, pages 155270.
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Xinying Ye, Takashi Toyama, Keiko Taguchi, Kotoko Arisawa, Takayuki Kaneko, Ryouhei Tsutsumi, Masayuki Yamamoto & Yoshiro Saito. (2023) Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2. Communications Biology 6:1.
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Mengyu Wang, Yubo Li, Yuhe Yang, Han Tao, Ghazala Mustafa, Fanliang Meng, Bo Sun, Jiansheng Wang, Yanting Zhao, Fen Zhang, Kejun Cheng & Qiaomei Wang. (2023) Biofortification of health-promoting glucosinolates in cruciferous sprouts along the whole agro-food chain. Trends in Food Science & Technology 140, pages 104164.
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Hua Fan, Qianqian Bai, Yang Yang, Xiaofei Shi, Ganqin Du, Junqiang Yan, Jian Shi & Dongmei Wang. (2023) The key roles of reactive oxygen species in microglial inflammatory activation: Regulation by endogenous antioxidant system and exogenous sulfur-containing compounds. European Journal of Pharmacology 956, pages 175966.
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Ting GaoJie Wang(b)Mengjie XiaoJie Wang(a)Shudong WangYufeng TangJingjing ZhangGuangping LuHua GuoYuanfang GuoQingbo LiuJiahao LiJunlian Gu. (2023) SESN2-Mediated AKT/GSK-3β/NRF2 Activation to Ameliorate Adriamycin Cardiotoxicity in High-Fat Diet–Induced Obese Mice. Antioxidants & Redox Signaling.
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Yan-qiong Zhang, Chun-xia Shi, Dan-mei Zhang, Lu-yi Zhang, Lu-wen Wang & Zuo-jiong Gong. (2023) Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity. Journal of Integrative Medicine.
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Jining Yang, Xinxin Guo, Tianyou Li, Yingquan Xie, Dawei Wang, Long Yi & Mantian Mi. (2023) Sulforaphane Inhibits Exhaustive Exercise-Induced Liver Injury and Transcriptome-Based Mechanism Analysis. Nutrients 15:14, pages 3220.
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Katiuska Tuttis, Ana Rita Thomazela Machado, Patrick Wellington da Silva Santos & Lusânia Maria Greggi Antunes. (2023) Sulforaphane Combined with Vitamin D Induces Cytotoxicity Mediated by Oxidative Stress, DNA Damage, Autophagy, and JNK/MAPK Pathway Modulation in Human Prostate Tumor Cells. Nutrients 15:12, pages 2742.
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Song-Bin Guo, Sheng Du, Ke-Yu Cai, Han-Jia Cai, Wei-Juan Huang & Xiao-Peng Tian. (2023) A scientometrics and visualization analysis of oxidative stress modulator Nrf2 in cancer profiles its characteristics and reveals its association with immune response. Heliyon 9:6, pages e17075.
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Zinian Wang, Marilyn L. Kwan, Reina Haque, Maciej Goniewicz, Rachel Pratt, Valerie S. Lee, Janise M. Roh, Isaac J. Ergas, Kimberly L. Cannavale, Ronald K. Loo, David S. Aaronson, Charles P. Quesenberry, Yuesheng Zhang, Christine B. Ambrosone, Lawrence H. Kushi & Li Tang. (2023) Associations of dietary isothiocyanate exposure from cruciferous vegetable consumption with recurrence and progression of non–muscle-invasive bladder cancer: findings from the Be-Well Study. The American Journal of Clinical Nutrition 117:6, pages 1110-1120.
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Siheng Liu, Yunbing Jia, Shirui Meng, Yiran Luo, Qi Yang & Zezheng Pan. (2023) Mechanisms of and Potential Medications for Oxidative Stress in Ovarian Granulosa Cells: A Review. International Journal of Molecular Sciences 24:11, pages 9205.
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Dan Shao, Wenxiang Shen, Yuyang Miao, Zhen Gao, Menghao Pan, Qiang Wei, Zuoting Yan, Xiaoe Zhao & Baohua Ma. (2023) Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis. Journal of Animal Science and Biotechnology 14:1.
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Xin Cheng, Jianhua Huang, Hongli Li, Di Zhao, Zhao Liu, Lemei Zhu, Zhen Zhang & Weijun Peng. (2023) Quercetin: A Promising Therapy for Diabetic Encephalopathy through Inhibition of Hippocampal Ferroptosis. Phytomedicine, pages 154887.
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Qian Li, Wen Zhang, Nuo Cheng, Yadi Zhu, Hao Li, Shuijun Zhang, Wenzhi Guo & Guangbo Ge. (2023) Pectolinarigenin ameliorates acetaminophen-induced acute liver injury via attenuating oxidative stress and inflammatory response in Nrf2 and PPARa dependent manners. Phytomedicine 113, pages 154726.
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Feng Liang, Ying Lv, Xiao Qiao, Shu Zhang, Shanshan Shen, Changcheng Wang, Guifang Xu, Xiaoping Zou, Lei Wang & Bin Zhang. (2023) Cinchonine‐induced cell death in pancreatic cancer cells by downregulating RRP15. Cell Biology International 47:5, pages 907-919.
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Liang Zhang, Shuxian Wang, Ying Zhang, Fenghuan Li & Chaoxiao Yu. (2023) Sulforaphane alleviates lung ischemia‑reperfusion injury through activating Nrf‑2/HO‑1 signaling. Experimental and Therapeutic Medicine 25:6.
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Chohee Kwon, Meran Keshawa Ediriweera & Somi Kim Cho. (2023) Interplay between Phytochemicals and the Colonic Microbiota. Nutrients 15:8, pages 1989.
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Nadia Salem Alrawaiq, Ahmed Atia & Azman Abdullah. (2023) Effect of Administration of an Equal Dose of Selected Dietary Chemicals on Nrf2 Nuclear Translocation in the Mouse Liver. Oxidative Medicine and Cellular Longevity 2023, pages 1-14.
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Nan Xing, Qinyun Du, Sa Guo, Gelin Xiang, Yi Zhang, Xianli Meng, Li Xiang & Shaohui Wang. (2023) Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy. Cell Death Discovery 9:1.
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Renjie Li, Shengyan Chen, Yangguang Li, Xuan Chen & Bang‐Ce Ye. (2022) Development of a “turn off–on” whole‐cell biosensor for sulforaphane detection based on the ultrasensitive activator HrpRS. Biotechnology and Applied Biochemistry 70:2, pages 798-810.
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Wenlan Li, Jennifer Trieu, Ronnie Blazev, Benjamin L. Parker, Kate T. Murphy, Kristy Swiderski & Gordon S. Lynch. (2023) Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes. American Journal of Physiology-Cell Physiology 324:2, pages C205-C221.
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Z. Lin, H. Wang, J. Song, G. Xu, F. Lu, X. Ma, X. Xia, J. Jiang & F. Zou. (2023) The role of mitochondrial fission in intervertebral disc degeneration. Osteoarthritis and Cartilage 31:2, pages 158-166.
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Yunzhu Yang, Jiafa Zhang, Canhong Yang, Bo Dong, Yanhong Fu, Yuanyuan Wang, Ming Gong, Tao Liu, Pingming Qiu, Weibing Xie & Tianming Lü. (2023) Sulforaphane attenuates microglia-mediated neuronal damage by down-regulating the ROS/autophagy/NLRP3 signal axis in fibrillar Aβ-activated microglia. Brain Research 1801, pages 148206.
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Wen-Jiang He, Cheng-Hao Lv, Zhong Chen, Meng Shi, Chao-Xi Zeng, De-Xing Hou & Si Qin. (2023) The Regulatory Effect of Phytochemicals on Chronic Diseases by Targeting Nrf2-ARE Signaling Pathway. Antioxidants 12:2, pages 236.
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Guanqiong Na, Canxia He, Shunxi Zhang, Sicong Tian, Yongping Bao & Yujuan Shan. (2023) Dietary Isothiocyanates: Novel Insights into the Potential for Cancer Prevention and Therapy. International Journal of Molecular Sciences 24:3, pages 1962.
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Jinjin Pan, Rui Wang, Yandong Pei, Dingyou Wang, Na Wu, Yuke Ji, Qing Tang, Liang Liu, Ke Cheng, Qiwang Liu, Jian Sun, Miaomiao Gong, Xu Zheng, Junxia Li, Changlin Zhang & Yuhui Yuan. (2023) Sulforaphane alleviated vascular remodeling in hypoxic pulmonary hypertension via inhibiting inflammation and oxidative stress. The Journal of Nutritional Biochemistry 111, pages 109182.
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Ji Myung Choi, Eun Ju Cho, Hyun Young Kim, Ah Young Lee & Jine Shang Choi. (2022) Physicochemical characteristics and antioxidant activity of kimchi during fermentation. Journal of Applied Biological Chemistry 65:4, pages 321-327.
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Bruna L. R. Silva, Gisele Simão, Carmem D. L. Campos, Cinara R. A. V. Monteiro, Laryssa R. Bueno, Gabriel B. Ortis, Saulo J. F. Mendes, Israel Viegas Moreira, Daniele Maria-Ferreira, Eduardo M. Sousa, Flávia C. B. Vidal, Cristina de Andrade Monteiro, Valério Monteiro-Neto & Elizabeth S. Fernandes. (2022) In Silico and In Vitro Analysis of Sulforaphane Anti-Candida Activity. Antibiotics 11:12, pages 1842.
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Ileana Ramazzina, Veronica Lolli, Karen Lacey, Silvia Tappi, Pietro Rocculi & Massimiliano Rinaldi. (2022) Fresh-Cut Eruca Sativa Treated with Plasma Activated Water (PAW): Evaluation of Antioxidant Capacity, Polyphenolic Profile and Redox Status in Caco2 Cells. Nutrients 14:24, pages 5337.
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Farhad Pouremamali, Amir Pouremamali, Mehdi Dadashpour, Narges Soozangar & Farhad Jeddi. (2022) An update of Nrf2 activators and inhibitors in cancer prevention/promotion. Cell Communication and Signaling 20:1.
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Xiude Li, Yihan Wang, Guoping Zhao, Guangmin Liu, Pengjie Wang & Jinwang Li. (2022) Microorganisms—An Effective Tool to Intensify the Utilization of Sulforaphane. Foods 11:23, pages 3775.
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Yuting Zhang, Huiting Huang, Libo Jin & Sue Lin. (2022) Anticarcinogenic Effects of Isothiocyanates on Hepatocellular Carcinoma. International Journal of Molecular Sciences 23:22, pages 13834.
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María Ángeles Núñez-Sánchez, María Antonia Martínez-Sánchez, Marina Verdejo-Sánchez, Paula García-Ibáñez, Alba Oliva Bolarín, Bruno Ramos-Molina, Diego A. Moreno & Antonio J. Ruiz-Alcaraz. (2022) Anti-Leukemic Activity of Brassica-Derived Bioactive Compounds in HL-60 Myeloid Leukemia Cells. International Journal of Molecular Sciences 23:21, pages 13400.
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Yuanyuan Zhao, Louisa S Chard Dunmall, Zhenguo Cheng, Yaohe Wang & Lingling Si. (2022) Natural products targeting glycolysis in cancer. Frontiers in Pharmacology 13.
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Xing Niu, Lijie Chen, Yan Li, Zhijian Hu & Fei He. (2022) Ferroptosis, necroptosis, and pyroptosis in the tumor microenvironment: Perspectives for immunotherapy of SCLC. Seminars in Cancer Biology 86, pages 273-285.
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Tongtong Liu, Qi Jin, Feihong Ren, Liping Yang, Huimin Mao, Fang Ma, Yuyang Wang, Ping Li & Yongli Zhan. (2022) Potential therapeutic effects of natural compounds targeting autophagy to alleviate podocyte injury in glomerular diseases. Biomedicine & Pharmacotherapy 155, pages 113670.
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Shan-Ju Yeh & Bor-Sen Chen. (2022) Systems Medicine Design based on Systems Biology Approaches and Deep Neural Network for Gastric Cancer. IEEE/ACM Transactions on Computational Biology and Bioinformatics 19:5, pages 3019-3031.
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Yue Chen, Meng-huan Wang, Jin-yi Wu, Jian-yun Zhu, Chun-feng Xie, Xiao-ting Li, Jie-shu Wu, Shan-shan Geng, Ya-dong Li, Hong-yu Han & Cai-yun Zhong. (2022) ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2. The Journal of Nutritional Biochemistry 107, pages 109067.
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Chengzhi Liu, Wenkang Dong, Zhengshuai Lv, Li Kong & Xiang Ren. (2022) Thioredoxin-interacting protein in diabetic retinal neurodegeneration: A novel potential therapeutic target for diabetic retinopathy. Frontiers in Neuroscience 16.
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Mehri Nazeri, Houshang Nemati & Mozafar Khazaei. (2022) Nrf2 antioxidant pathway and apoptosis induction and inhibition of NF-κB-mediated inflammatory response in human prostate cancer PC3 cells by Brassica oleracea var. acephala: An in vitro study. Molecular Biology Reports 49:8, pages 7251-7261.
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Shanyi Li, Hsiao-Chen Dina Kuo, Lujing Wang, Renyi Wu, Davit Sargsyan & Ah-Ng Kong. (2022) UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes. Chemical Research in Toxicology 35:7, pages 1220-1233.
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Yongyan Zhang, Yadi Zhu, Ying Li, Feng Ji, Guangbo Ge & Hua Xu. (2022) Midazolam Ameliorates Acute Liver Injury Induced by Carbon Tetrachloride via Enhancing Nrf2 Signaling Pathway. Frontiers in Pharmacology 13.
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Qianlei Yang, Rui Yan, Yuemei Mo, Haixuan Xia, Hanyi Deng, Xiaojuan Wang, Chunchun Li, Koichi Kato, Hengdong Zhang, Tingxu Jin, Jie Zhang & Yan An. (2022) The Potential Key Role of the NRF2/NQO1 Pathway in the Health Effects of Arsenic Pollution on SCC. International Journal of Environmental Research and Public Health 19:13, pages 8118.
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Hong Liu, Ming-Jun Li, Xiu-Ning Zhang, Shuo Wang, Long-Xia Li, Fang-Fang Guo & Tao Zeng. (2022) N,N-dimethylformamide-induced acute liver damage is driven by the activation of NLRP3 inflammasome in liver macrophages of mice. Ecotoxicology and Environmental Safety 238, pages 113609.
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Zinian Wang, Chengjian Tu, Rachel Pratt, Thaer Khoury, Jun Qu, Jed W. Fahey, Susan E. McCann, Yuesheng Zhang, Yue Wu, Alan D. Hutson, Christine B. Ambrosone, Stephen B. Edge, Helen H. Cappuccino, Kazuaki Takabe, Jessica S. Young & Li Tang. (2022) A Presurgical‐Window Intervention Trial of Isothiocyanate‐Rich Broccoli Sprout Extract in Patients with Breast Cancer. Molecular Nutrition & Food Research 66:12.
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Antonio José Ruiz-Alcaraz, María Antonia Martínez-Sánchez, Pilar García-Peñarrubia, María Martinez-Esparza, Bruno Ramos-Molina & Diego A. Moreno. (2022) Analysis of the anti-inflammatory potential of Brassica bioactive compounds in a human macrophage-like cell model derived from HL-60 cells. Biomedicine & Pharmacotherapy 149, pages 112804.
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Shiyu Wang, Yanan Wang, Xiangnan Liu, Yongbin Yang, Sufang Wu & Yuan Liu. (2022) SFN Enhanced the Radiosensitivity of Cervical Cancer Cells via Activating LATS2 and Blocking Rad51/MDC1 Recruitment to DNA Damage Site. Cancers 14:8, pages 1872.
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An-Guo Wu, Yuan-Yuan Yong, Yi-Ru Pan, Li Zhang, Jian-Ming Wu, Yue Zhang, Yong Tang, Jing Wei, Lu Yu, Betty Yuen-Kwan Law, Chong-Lin Yu, Jian Liu, Cai Lan, Ru-Xiang Xu, Xiao-Gang Zhou & Da-Lian Qin. (2022) Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals. Oxidative Medicine and Cellular Longevity 2022, pages 1-24.
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Wensi Zheng, Xiaolong Li, Tianhong Zhang & Jijun Wang. (2022) Biological mechanisms and clinical efficacy of sulforaphane for mental disorders. General Psychiatry 35:2, pages e100700.
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Dongyu Hua, Ailin Luo, Zifeng Wu, Chaoli Huang, Shan Li, Xiaolin Xu, Jiali Xu, Chun Yang, Di Wang & Cunming Liu. (2022) Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling. Brain Research Bulletin 181, pages 1-11.
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Xiucui Li, Huiya Ying, Zilong Zhang, Zijing Yang, Cancan You, Xiaohong Cai, Zhongdong Lin & Yanfeng Xiao. (2022) Sulforaphane Attenuates Chronic Intermittent Hypoxia-Induced Brain Damage in Mice via Augmenting Nrf2 Nuclear Translocation and Autophagy. Frontiers in Cellular Neuroscience 16.
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Yaqian Wang, Fangfang Chen, Yuan Zhang, Xiangyu Zheng, Shiyan Liu, Meijuan Tang, Ziling Wang, Pan Wang, Yongping Bao & Dan Li. (2022) Biphasic effect of sulforaphane on angiogenesis in hypoxia via modulation of both Nrf2 and mitochondrial dynamics . Food & Function 13:5, pages 2884-2898.
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Koji Ishida, Kosuke Kaji, Shinya Sato, Hiroyuki Ogawa, Hirotetsu Takagi, Hiroaki Takaya, Hideto Kawaratani, Kei Moriya, Tadashi Namisaki, Takemi Akahane & Hitoshi Yoshiji. (2021) Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. The Journal of Nutritional Biochemistry 89, pages 108573.
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Jie Wang, Ke-yong Tian, Ying Fang, Hui-min Chang, Ya-nan Han & Fu-quan Chen. (2021) Sulforaphane attenuates cisplatin-induced hearing loss by inhibiting histone deacetylase expression. International Journal of Immunopathology and Pharmacology 35, pages 205873842110340.
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Ping Zhang, Tingting Li, Chang Liu, Mustafa Sindi, Xin Cheng, Shuangyu Qi, Xinyue Liu, Yu Yan, Yongping Bao, Beate Brand-Saberi, Weidong Yang, Guang Wang & Xuesong Yang. (2021) Nano-sulforaphane attenuates PhIP-induced early abnormal embryonic neuro-development. Annals of Anatomy - Anatomischer Anzeiger 233, pages 151617.
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Yu Du, Qian Wang, Na Tian, Meng Lu, Xian-Long Zhang & Sheng-Ming Dai. (2020) Knockdown of nrf2 Exacerbates TNF-α-Induced Proliferation and Invasion of Rheumatoid Arthritis Fibroblast-Like Synoviocytes through Activating JNK Pathway. Journal of Immunology Research 2020, pages 1-12.
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Paula García-Ibañez, Lucía Yepes-Molina, Antonio J. Ruiz-Alcaraz, María Martínez-Esparza, Diego A. Moreno, Micaela Carvajal & Pilar García-Peñarrubia. (2020) Brassica Bioactives Could Ameliorate the Chronic Inflammatory Condition of Endometriosis. International Journal of Molecular Sciences 21:24, pages 9397.
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A. Langston-Cox, C.H. Leo, M. Tare, E.M. Wallace & S.A. Marshall. (2020) Sulforaphane improves vascular reactivity in mouse and human arteries after “preeclamptic-like” injury. Placenta 101, pages 242-250.
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Alistair R. Mallard, Jemima G. Spathis & Jeff S. Coombes. (2020) Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and exercise. Free Radical Biology and Medicine 160, pages 471-479.
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Yuan Rong, Lanxiang Huang, Kezhen Yi, Hao Chen, Shaoping Liu, Wuwen Zhang, Chunhui Yuan, Xuemin Song & Fubing Wang. (2020) Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells. Cancer Letters 493, pages 189-196.
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Danfeng Xue, Xiongming Zhou & Jiaxuan Qiu. (2020) Emerging role of NRF2 in ROS-mediated tumor chemoresistance. Biomedicine & Pharmacotherapy 131, pages 110676.
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Geting Wu, Yuanliang Yan, Yangying Zhou, Yumei Duan, Shuangshuang Zeng, Xiang Wang, Wei Lin, Chunlin Ou, Jianhua Zhou & Zhijie Xu. (2020) Sulforaphane: Expected to Become a Novel Antitumor Compound. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 28:4, pages 439-446.
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Ting-Ting Gong, Xiao-Dong Liu, Zhi-Peng Zhan & Qi-Jun Wu. (2020) Sulforaphane enhances the cisplatin sensitivity through regulating DNA repair and accumulation of intracellular cisplatin in ovarian cancer cells. Experimental Cell Research 393:2, pages 112061.
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