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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 24, 2009 - Issue 1
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Research Article

New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors

Muhammad Nisar Institute of Chemical Sciences and Department of Pharmacy, University of Peshawar, Peshawar 25120, PakistanCorrespondence[email protected]
,
Obaidullah Institute of Chemical Sciences and Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
,
Manzoor Ahmad H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
,
Noreen Wadood Department of Biochemistry, Kabir Medical College, Peshawar, Pakistan
,
Muhammad Arif Lodhi H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
,
Farzana Shaheen H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
&
M. Iqbal Choudhary H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
 show all
Pages 47-51 | Received 10 Oct 2007, Accepted 07 Nov 2007, Published online: 20 Oct 2008

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Zhi-Hui Luo, Yang Chen, Xin-Yi Sun, Hua Fan, Wei Li, Liang Deng & Tian-Peng Yin. (2020) A new diterpenoid alkaloid from Aconitum hemsleyanum. Natural Product Research 34:9, pages 1331-1336.
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Nidhi S. Belwal, Barkha Kamal, Vikas Sharma, Sanjay Gupta, Anoop Kumar Dobriyal & Vikash S. Jadon. (2016) Production of genetically uniform plants from shoot tips of Aconitum heterophyllum Wall. – a critically endangered medicinal herb. The Journal of Horticultural Science and Biotechnology 91:5, pages 529-535.
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Syed Mudassir Jeelani, Mohmmad Abubakar Ahmad Siddique & Savita Rani. (2015) Variations of morphology, ecology and chromosomes of Aconitum heterophyllum Wall., an endangered Alpine medicinal plant in Himalayas. Caryologia 68:4, pages 294-305.
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Kinjal Chauhan, Navin Sheth, Vishavas Ranpariya & Sachin Parmar. (2011) Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents. Pharmaceutical Biology 49:2, pages 194-199.
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Shyh-Ying Chiou, Chun-Fu Huang, Shih-Jei Yeh, I-Ru Chen & Gialih Lin. (2010) Stereoselective inhibition of butyrylcholinesterase by enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates. Journal of Enzyme Inhibition and Medicinal Chemistry 25:1, pages 13-20.
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Articles from other publishers (24)

Anmol, Gaurav Aggarwal, Mehak Sharma, Raman Singh, Shivani & Upendra Sharma. (2024) Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality control, conservation status and future prospective. Journal of Ethnopharmacology 320, pages 117385.
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Sekhar Tiwari, Puja Acharya, Bharat Solanki, Anish Kumar Sharma & Sandeep Rawat. (2023) A review on efforts for improvement in medicinally important chemical constituents inAconitum through biotechnological interventions. 3 Biotech 13:6.
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Anna MathewK. S. ChandrashekarAnoop KishoreVasudev PaiH. N Aswatha RamRamadevi Pemmereddy. (2023) Therapeutic Potential of Aconitum heterophyllum: A Review on Phyto-pharmacological properties. Research Journal of Pharmacy and Technology, pages 470-476.
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Lingli Chen, Mei Tian, Baolong Jin, Biwei Yin, Tong Chen, Juan Guo, Jinfu Tang, Guanghong Cui & Luqi Huang. (2022) Integrating Metabolomics and Transcriptomics to Unveil Atisine Biosynthesis in Aconitum gymnandrum Maxim. International Journal of Molecular Sciences 23:21, pages 13463.
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Zishan Ahmad Wani, Adil Farooq, Sobia Sarwar, Vikram S. Negi, Ali Asghar Shah, Bikarma Singh, Sazada Siddiqui, Shreekar Pant, Huda Alghamdi & Mahmoud Mustafa. (2022) Scientific Appraisal and Therapeutic Properties of Plants Utilized for Veterinary Care in Poonch District of Jammu and Kashmir, India. Biology 11:10, pages 1415.
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Tareq A. Wani, Zahoor A. Kaloo & Nisar A. Dangroo. (2022) Aconitum heterophyllum Wall. ex Royle: A critically endangered medicinal herb with rich potential for use in medicine. Journal of Integrative Medicine 20:2, pages 104-113.
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S. Ahmad, Zainab, H. Ahmad, I. Khan, S. Alghamdi, M. Almehmadi, M. Ali, A. Ullah, H. Hussain, N. M. Khan, F. Ali & M. Ahmad. (2022) Green synthesis of gold nanaoparticles using Delphinium Chitralense tuber extracts, their characterization and enzyme inhibitory potential. Brazilian Journal of Biology 82.
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Amin Mahmood Thawabteh, Alà Thawabteh, Filomena Lelario, Sabino Aurelio Bufo & Laura Scrano. (2021) Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids. Molecules 26:13, pages 4103.
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Li MI, Yu-Chen LI, Meng-Ru SUN, Pei-Lin ZHANG, Yi LI & Hua YANG. (2021) A systematic review of pharmacological activities, toxicological mechanisms and pharmacokinetic studies on Aconitum alkaloids. Chinese Journal of Natural Medicines 19:7, pages 505-520.
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Sabeena Ali, Rekha Chouhan, Phalisteen Sultan, Qazi Parvaiz Hassan & Sumit G. Gandhi. (2021) A comprehensive review of phytochemistry, pharmacology and toxicology of the genus Aconitum L.. Advances in Traditional Medicine.
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Nikhil Malhotra & Shivani Sharma. 2021. Himalayan Medicinal Plants. Himalayan Medicinal Plants 5 25 .
Christophe Wiart. 2021. Medicinal Plants in Asia and Pacific for Parasitic Infections. Medicinal Plants in Asia and Pacific for Parasitic Infections 97 115 .
Prateek Singh Bora, Patil Shivprasad Suresh, Surekha Kumari, Anmol, Shivani Puri & Upendra Sharma. 2021. Medicinal Plants. Medicinal Plants 721 768 .
Yong Shen, Wen-Juan Liang, Ya-Na Shi, Edward J. Kennelly & Da-Ke Zhao. (2020) Structural diversity, bioactivities, and biosynthesis of natural diterpenoid alkaloids. Natural Product Reports 37:6, pages 763-796.
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Shahid AkbarShahid Akbar. 2020. Handbook of 200 Medicinal Plants. Handbook of 200 Medicinal Plants 81 88 .
Hanif Ahmad, Shujaat Ahmad, Syed Adnan Ali Shah, Abdul Latif, Mumtaz Ali, Farman Ali Khan, Muhammad Nawaz Tahir, Farzana Shaheen, Abdul Wadood & Manzoor Ahmad. (2017) Antioxidant and anticholinesterase potential of diterpenoid alkaloids from Aconitum heterophyllum. Bioorganic & Medicinal Chemistry 25:13, pages 3368-3376.
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Janhvi Mishra Rawat, Balwant Rawat, Aakriti Bhandari, Shambhavi Yadav, Susmita Mishra, Anup Chandra & SN Mishra. (2016) Aconitum biotechnology: recent trends and emerging perspectives. Acta Physiologiae Plantarum 38:12.
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Jambey Tsering, Hui Tag, Baikuntha Jyoti Gogoi & Vijay Veer. 2016. Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization. Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization 189 203 .
Da Cheng Hao, Xiao-Jie Gu & Pei Gen Xiao. 2015. Medicinal Plants. Medicinal Plants 253 292 .
Eric Nyirimigabo, Yanyan Xu, Yubo Li, Yuming Wang, Kojo Agyemang & Yanjun Zhang. (2015) A review on phytochemistry, pharmacology and toxicology studies of Aconitum . Journal of Pharmacy and Pharmacology 67:1, pages 1-19.
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Nikhil Malhotra, Varun Kumar, Hemant Sood, Tiratha Raj Singh & Rajinder Singh Chauhan. (2014) Multiple genes of mevalonate and non-mevalonate pathways contribute to high aconites content in an endangered medicinal herb, Aconitum heterophyllum Wall. Phytochemistry 108, pages 26-34.
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Sergiy Kostenko, Mahmud Tareq Hassan Khan, Ingebrigt Sylte & Ugo Moens. (2010) The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor. Cellular and Molecular Life Sciences 68:2, pages 289-301.
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Nidhi Srivastava, Vikas Sharma, Barkha Kamal, A.K. Dobriyal & Vikash S. Jadon. (2010) Polyphenolics Free DNA Isolation from Different Types of Tissues of Aconitum heterophyllum Wall-endangered Medicinal Species. Journal of Plant Sciences 5:4, pages 414-419.
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Feng-Peng Wang & Qiao-Hong Chen. 2010. 1 577 .

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