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Review Article

Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a review

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Pages 1652-1659 | Received 08 Aug 2019, Accepted 30 Aug 2019, Published online: 17 Sep 2019

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Read on this site (6)

Tuba Tekeli, Suleyman Akocak, Andrea Petreni, Nebih Lolak, Servet Çete & Claudiu T. Supuran. (2023) Potent carbonic anhydrase I, II, IX and XII inhibition activity of novel primary benzenesulfonamides incorporating bis-ureido moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Claudiu T Supuran. (2023) An overview of novel antimicrobial carbonic anhydrase inhibitors. Expert Opinion on Therapeutic Targets 27:10, pages 897-910.
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Andrea Angeli, Linda J Urbański, Clemente Capasso, Seppo Parkkila & Claudiu T. Supuran. (2022) Activation studies with amino acids and amines of a β-carbonic anhydrase from Mammaliicoccus (Staphylococcus) sciuri previously annotated as Staphylococcus aureus (SauBCA) carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2786-2792.
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Andrea Angeli, Linda J. Urbański, Vesa P. Hytönen, Seppo Parkkila & Claudiu T. Supuran. (2021) Activation of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with amines and amino acids. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 758-763.
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Claudiu T. Supuran. (2020) Coumarin carbonic anhydrase inhibitors from natural sources. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1462-1470.
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Niccolò Chiaramonte, Soumia Maach, Caterina Biliotti, Andrea Angeli, Gianluca Bartolucci, Laura Braconi, Silvia Dei, Elisabetta Teodori, Claudiu T. Supuran & Maria Novella Romanelli. (2020) Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine1. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1003-1010.
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Rehab F. Ahmed, Walaa R. Mahmoud, Nagwa M. Abdelgawad, Marwa A. Fouad & Mona F. Said. (2023) Exploring novel anticancer pyrazole benzenesulfonamides featuring tail approach strategy as carbonic anhydrase inhibitors. European Journal of Medicinal Chemistry 261, pages 115805.
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Samaa Saied, Moataz Shaldam, Mostafa M. Elbadawi, Simone Giovannuzzi, Alessio Nocentini, Hadia Almahli, Rofaida Salem, Tamer M. Ibrahim, Claudiu T. Supuran & Wagdy M. Eldehna. (2023) Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties. European Journal of Medicinal Chemistry 259, pages 115707.
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Ayse Er. (2023) Various Carbonic Anhydrases in Physiopathological Events, Carbonic Anhydrase Inhibitors, and Hybrid Compounds. Letters in Drug Design & Discovery 20:10, pages 1427-1436.
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Suleyman Akocak, Nebih Lolak, Simone Giovannuzzi & Claudiu T. Supuran. (2023) Potent and selective carbonic anhydrase inhibition activities of pyrazolones bearing benzenesulfonamides. Bioorganic & Medicinal Chemistry Letters 95, pages 129479.
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Anindita Hazarika & Meera Yadav. (2023) Biomineralization of carbon dioxide by carbonic anhydrase. Biocatalysis and Agricultural Biotechnology 51, pages 102755.
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Suleyman Akocak, Nebih Lolak, Hatice Esra Duran, Mesut Işık, Cüneyt Türkeş, Mustafa Durgun & Şükrü Beydemir. (2023) Synthesis and Characterization of Novel 1,3‐Diaryltriazene‐Substituted Sulfaguanidine Derivatives as Selective Carbonic Anhydrase Inhibitors: Biological Evaluation, in Silico ADME/T and Molecular Docking Study . Chemistry & Biodiversity 20:8.
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Noura G. Eissa, Wagdy M. Eldehna, Esraa B. Abdelazim, Rana A. Eissa, Hend H. Mohamed, Nadeen H. Diab, Mahmoud A. El Hassab, Eslam B. Elkaeed, Zainab M. Elsayed, Marwa A. Sabet, Marwa H. Bakr, Ashraf Aboelela, Nahla A. Abdelshafi, Elbadawy A. Kamoun, Claudiu T. Supuran, Mahmoud Elsabahy & Ayat A. Allam. (2023) Morphologic design of nanogold carriers for a carbonic anhydrase inhibitor: Effect on ocular retention and intraocular pressure. International Journal of Pharmaceutics 642, pages 123161.
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Mohammad Sadegh Gheibzadeh, Colleen Varaidzo Manyumwa, Özlem Tastan Bishop, Hossein Shahbani Zahiri, Seppo Parkkila & Reza Zolfaghari Emameh. (2023) Genome Study of α-, β-, and γ-Carbonic Anhydrases from the Thermophilic Microbiome of Marine Hydrothermal Vent Ecosystems. Biology 12:6, pages 770.
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Monalisa Mahapatra, Suman K. Mekap, Suvadeep Mal, Jyotirmaya Sahoo, Sanjeeb K. Sahoo & Sudhir K. Paidesetty. (2023) Coumaryl‐sulfonamide moiety: Unraveling their synthetic strategy and specificity toward  h CA IX/XII, facilitating anticancer drug development . Archiv der Pharmazie 356:4.
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Balasaheb D. Vanjare, Nam Gyu Choi, Young Seok Eom, Hussain Raza, Mubashir Hassan, Ki Hwan Lee & Song Ja Kim. (2022) Synthesis, carbonic anhydrase inhibition, anticancer activity, and molecular docking studies of 1,3,4-oxadiazole derivatives. Molecular Diversity 27:1, pages 193-208.
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Yanyou Wu & Sen RaoYanyou Wu & Sen Rao. 2023. Root-Derived Bicarbonate Assimilation in Plants. Root-Derived Bicarbonate Assimilation in Plants 55 95 .
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Giulia Arrighi, Adrián Puerta, Andrea Petrini, Francisco J. Hicke, Alessio Nocentini, Miguel X. Fernandes, José M. Padrón, Claudiu T. Supuran, José G. Fernández-Bolaños & Óscar López. (2022) Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking Simulations. International Journal of Molecular Sciences 23:14, pages 7685.
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Ashok Aspatwar, Martti E. E. Tolvanen, Harlan Barker, Leo Syrjänen, Susanna Valanne, Sami Purmonen, Abdul Waheed, William S. Sly & Seppo Parkkila. (2022) Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology. Physiological Reviews 102:3, pages 1327-1383.
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Ayanne de Oliveira Maciel, Paul Christakopoulos, Ulrika Rova & Io Antonopoulou. (2022) Carbonic anhydrase to boost CO2 sequestration: Improving carbon capture utilization and storage (CCUS). Chemosphere 299, pages 134419.
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Pengcheng Lv, Yinyi Cai, Jiayi Luo & Kun Chen. (2022) Recent Advances in the Design and Synthesis of Small Molecule Carbonic Anhydrase IX Inhibitors. Current Topics in Medicinal Chemistry 22:7, pages 550-560.
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Andrea Angeli, Emanuela Berrino, Simone Carradori, Claudiu T. Supuran, Marzia Cirri, Fabrizio Carta & Gabriele Costantino. (2021) Amine- and Amino Acid-Based Compounds as Carbonic Anhydrase Activators. Molecules 26:23, pages 7331.
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Emma Langella, Martina Buonanno, Giuseppina De Simone & Simona Maria Monti. (2020) Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain. Cellular and Molecular Life Sciences 78:5, pages 2059-2067.
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Özlem Akgül, Andrea Angeli, Daniela Vullo, Fabrizio Carta & Claudiu T. Supuran. (2020) Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors. Bioorganic Chemistry 103, pages 104236.
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Suleyman Akocak, Özlen Güzel-Akdemir, Rajesh Kishore Kumar Sanku, Samson S. Russom, Bogdan I. Iorga, Claudiu T. Supuran & Marc A. Ilies. (2020) Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII. Bioorganic Chemistry 103, pages 104204.
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Daisy L. Wong, Amelia T. Yuan, Natalie C. Korkola & Martin J. Stillman. (2020) Interplay between Carbonic Anhydrases and Metallothioneins: Structural Control of Metalation. International Journal of Molecular Sciences 21:16, pages 5697.
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Anna Dreyer, Alexander Schackmann, Alexandre Kriznik, Kamel Chibani, Corinna Wesemann, Lara Vogelsang, André Beyer & Karl-Josef Dietz. (2020) Thiol Redox Regulation of Plant β-Carbonic Anhydrase. Biomolecules 10:8, pages 1125.
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Nebih Lolak, Süleyman Akocak, Cüneyt Türkeş, Parham Taslimi, Mesut Işık, Şükrü Beydemir, İlhami Gülçin & Mustafa Durgun. (2020) Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorganic Chemistry 100, pages 103897.
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Andrea Angeli, Marta Ferraroni, Mariana Pinteala, Stelian S. Maier, Bogdan C. Simionescu, Fabrizio Carta, Sonia Del Prete, Clemente Capasso & Claudiu T. Supuran. (2020) Crystal Structure of a Tetrameric Type II β-Carbonic Anhydrase from the Pathogenic Bacterium Burkholderia pseudomallei. Molecules 25:10, pages 2269.
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Vikas Sharma, Rajiv Kumar, Andrea Angeli, Claudiu T. Supuran & Pawan K. Sharma. (2020) Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes. European Journal of Medicinal Chemistry 193, pages 112219.
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