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Short Communication

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase

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Pages 506-510 | Received 09 Dec 2019, Accepted 01 Jan 2020, Published online: 13 Jan 2020

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Jekaterīna Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Jekaterina Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) 1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 225-238.
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Evgeny Chupakhin & Mikhail Krasavin. (2021) Thioredoxin reductase inhibitors: updated patent review (2017-present). Expert Opinion on Therapeutic Patents 31:8, pages 745-758.
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Claudiu T. Supuran. (2021) Multitargeting approaches involving carbonic anhydrase inhibitors: hybrid drugs against a variety of disorders. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1702-1714.
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Anna Jastrząb & Elżbieta Skrzydlewska. (2021) Thioredoxin-dependent system. Application of inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 362-371.
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Claudiu T. Supuran. (2020) Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery. Expert Opinion on Drug Discovery 15:6, pages 671-686.
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Mikhail Krasavin, Stanislav Kalinin, Tatiana Sharonova & Claudiu T. Supuran. (2020) Inhibitory activity against carbonic anhydrase IX and XII as a candidate selection criterion in the development of new anticancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1555-1561.
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Claudiu T. Supuran. (2020) Coumarin carbonic anhydrase inhibitors from natural sources. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1462-1470.
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Barbara Kaproń, Robert Czarnomysy, Mariusz Wysokiński, Rudolf Andrys, Kamil Musilek, Andrea Angeli, Claudiu T. Supuran & Tomasz Plech. (2020) 1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 993-1002.
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Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran & Raivis Žalubovskis. (2022) Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases. International Journal of Molecular Sciences 23:22, pages 14115.
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Naying Chu, Yitong Wang, Hao Jia, Jie Han, Xiaoyi Wang & Zhuang Hou. (2022) Design, Synthesis and Biological Evaluation of New Carbohydrate-Based Coumarin Derivatives as Selective Carbonic Anhydrase IX Inhibitors via “Click” Reaction. Molecules 27:17, pages 5464.
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Yuan Huang, Xueyan Zhao, Dengfeng Chen, Yu Zheng, Jinyue Luo & Shenlin Huang. (2022) Access to Sulfocoumarins by Three‐Component Reaction of β‐Keto Sulfonyl Fluorides, Arynes, and DMF. European Journal of Organic Chemistry 2022:27.
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Dengfeng Chen, Xingliang Nie, Qingyuan Feng, Yingyin Zhang, Yiheng Wang, Qiuyue Wang, Lin Huang, Shenlin Huang & Saihu Liao. (2021) Electrochemical Oxo‐Fluorosulfonylation of Alkynes under Air: Facile Access to β‐Keto Sulfonyl Fluorides. Angewandte Chemie International Edition 60:52, pages 27271-27276.
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Dmitry Dar'in, Grigory Kantin, Stanislav Kalinin, Tatiana Sharonova, Alexander Bunev, Gennady I. Ostapenko, Alessio Nocentini, Vladimir Sharoyko, Claudiu T. Supuran & Mikhail Krasavin. (2021) Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide – A new caspase-activating proapoptotic agent. European Journal of Medicinal Chemistry 222, pages 113589.
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Tatiana Sharonova, Polina Paramonova, Stanislav Kalinin, Alexander Bunev, Rovshan Е. Gasanov, Alessio Nocentini, Vladimir Sharoyko, Tatiana B. Tennikova, Dmitry Dar’in, Claudiu T. Supuran & Mikhail Krasavin. (2021) Insertion of metal carbenes into the anilinic N–H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms. European Journal of Medicinal Chemistry 218, pages 113352.
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Shubham Kumar, Sandeep Rulhania, Shalini Jaswal & Vikramdeep Monga. (2021) Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors. European Journal of Medicinal Chemistry 209, pages 112923.
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Francesca Annunziata, Cecilia Pinna, Sabrina Dallavalle, Lucia Tamborini & Andrea Pinto. (2020) An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities. International Journal of Molecular Sciences 21:13, pages 4618.
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Aiga Grandane, Alessio Nocentini, Thomas Werner, Raivis Zalubovskis & Claudiu T. Supuran. (2020) Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 28:11, pages 115496.
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