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Review Article

An overview on the recently discovered iota-carbonic anhydrases

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Pages 1988-1995 | Received 31 Jul 2021, Accepted 17 Aug 2021, Published online: 06 Sep 2021

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Lisa Sequeira, Simona Distinto, Rita Meleddu, Marco Gaspari, Andrea Angeli, Filippo Cottiglia, Daniela Secci, Alessia Onali, Erica Sanna, Fernanda Borges, Eugenio Uriarte, Stefano Alcaro, Claudiu T. Supuran & Elias Maccioni. (2023) 2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Romeo Romagnoli, Tiziano De Ventura, Stefano Manfredini, Erika Baldini, Claudiu T. Supuran, Alessio Nocentini, Andrea Brancale, Roberta Bortolozzi, Lorenzo Manfreda & Giampietro Viola. (2023) Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Waleed A. Badawi, Mahmoud Rashed, Alessio Nocentini, Alessandro Bonardi, Mohammad M. Abd-Alhaseeb, Sara T. Al-Rashood, Giri Babu Veerakanellore, Taghreed A. Majrashi, Eslam B. Elkaeed, Bahaa Elgendy, Paola Gratteri, Claudiu T. Supuran, Wagdy M. Eldehna & Mohamed Elagawany. (2023) Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T. Supuran & Antonello Mai. (2023) Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Simone Giovannuzzi, Viviana De Luca, Clemente Capasso & Claudiu T. Supuran. (2023) Inhibition studies with simple and complex (in)organic anions of the γ-carbonic anhydrase from Mammaliicoccus (Staphylococcus) sciuri, MscCAγ. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Andrea Angeli & Claudiu T. Supuran. (2023) Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Maristela Barbosa Portela, Caroliny Mello Barboza, Eduardo Moreira da Silva, Daniel Clemente de Moraes, Renata Antoun Simão, Clara Ribeiro de Souza, Verônica da Silva Cardoso, Antônio Ferreira-Pereira, Alane Beatriz Vermelho & Claudiu T. Supuran. (2023) Dentine biomodification by sulphonamides pre-treatment: bond strength, proteolytic inhibition, and antimicrobial activity. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 319-329.
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Morteza Abdoli, Alessandro Bonardi, Claudiu T. Supuran & Raivis Žalubovskis. (2023) 4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 156-165.
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Claudiu T Supuran. (2023) An overview of novel antimicrobial carbonic anhydrase inhibitors. Expert Opinion on Therapeutic Targets 27:10, pages 897-910.
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Claudiu T Supuran. (2023) Targeting carbonic anhydrases for the management of hypoxic metastatic tumors. Expert Opinion on Therapeutic Patents 0:0, pages 1-20.
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Andrea Angeli, Linda J Urbański, Clemente Capasso, Seppo Parkkila & Claudiu T. Supuran. (2022) Activation studies with amino acids and amines of a β-carbonic anhydrase from Mammaliicoccus (Staphylococcus) sciuri previously annotated as Staphylococcus aureus (SauBCA) carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2786-2792.
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Viviana De Luca, Vincenzo Carginale, Claudiu T. Supuran & Clemente Capasso. (2022) The gram-negative bacterium Escherichia coli as a model for testing the effect of carbonic anhydrase inhibition on bacterial growth. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2092-2098.
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Simone Giovannuzzi, Viviana De Luca, Alessio Nocentini, Clemente Capasso & Claudiu T. Supuran. (2022) Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 680-685.
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Viviana De Luca, Andrea Angeli, Valeria Mazzone, Claudia Adelfio, Vincenzo Carginale, Andrea Scaloni, Fabrizio Carta, Silvia Selleri, Claudiu T. Supuran & Clemente Capasso. (2022) Heterologous expression and biochemical characterisation of the recombinant β-carbonic anhydrase (MpaCA) from the warm-blooded vertebrate pathogen malassezia pachydermatis. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 62-68.
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Sridhar Goud Nerella, Priti Singh, Mohammed Arifuddin & Claudiu T Supuran. (2022) Anticancer carbonic anhydrase inhibitors: a patent and literature update 2018-2022. Expert Opinion on Therapeutic Patents 32:8, pages 833-847.
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Paul Dowling, Stephen Gargan, Margit Zweyer, Hemmen Sabir, Dieter Swandulla & Kay Ohlendieck. (2021) Proteomic profiling of carbonic anhydrase CA3 in skeletal muscle. Expert Review of Proteomics 18:12, pages 1073-1086.
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Clemente Capasso. (2023) Carbonic Anhydrases: A Superfamily of Ubiquitous Enzymes. International Journal of Molecular Sciences 24:8, pages 7014.
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Xing-Jie Dai, Lei-Peng Xue, Shi-Kun Ji, Ying Zhou, Ya Gao, Yi-Chao Zheng, Hui-Min Liu & Hong-Min Liu. (2023) Triazole-fused pyrimidines in target-based anticancer drug discovery. European Journal of Medicinal Chemistry 249, pages 115101.
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Seong-Ki Lee, Walter F. Boron & Rossana Occhipinti. (2023) Potential Novel Role of Membrane-Associated Carbonic Anhydrases in the Kidney. International Journal of Molecular Sciences 24:4, pages 4251.
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Balasaheb D. Vanjare, Nam Gyu Choi, Young Seok Eom, Hussain Raza, Mubashir Hassan, Ki Hwan Lee & Song Ja Kim. (2022) Synthesis, carbonic anhydrase inhibition, anticancer activity, and molecular docking studies of 1,3,4-oxadiazole derivatives. Molecular Diversity 27:1, pages 193-208.
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Yoshihisa Hirakawa, Yutaka Hanawa, Kohei Yoneda & Iwane Suzuki. (2022) Evolution of a chimeric mitochondrial carbonic anhydrase through gene fusion in a haptophyte alga. FEBS Letters 596:23, pages 3051-3059.
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