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Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer

Xianmin MuDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaORCID Iconhttp://orcid.org/0000-0002-2365-9321View further author information
ORCID Icon,
Wei ShiDepartment of Drug Screening and Evaluation, Chia Tai Tianqing Pharmaceutical Group Co., Ltd,Nanjing, Jiangsu210023, ChinaView further author information
,
Yue XuDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Che XuDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Ting ZhaoDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Biao GengDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Jing YangDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Jinshun PanDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Shi HuDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Chen ZhangDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Juan ZhangDepartment of Drug Clinical Trial Institution, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Chao WangDepartment of Surgery, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Jiajia ShenDepartment of Surgery, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Yin CheMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Zheng LiuMedical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Yuanfang LvDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
,
Hao WenDepartment of Surgery, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, ChinaView further author information
&
Qiang YouDepartment of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, China;Medical Center for Digestive Diseases, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu210011, China;Department of Immunology, Nanjing Medical University, Nanjing, Jiangsu211166, China;Key Laboratory for Aging & Disease, Nanjing Medical University, Nanjing, Jiangsu, ChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3308-4127View further author information
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Pages 428-438 | Received 06 Nov 2017, Accepted 17 Feb 2018, Published online: 27 Mar 2018

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