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Research Article

Protective Effect of Ethanolic Extract of Seeds of Moringa oleifera Lam. Against Inflammation Associated with Development of Arthritis in Rats

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Pages 39-47 | Received 03 Oct 2006, Accepted 02 Nov 2006, Published online: 09 Oct 2008

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Kaushal H. Shah & Manisha J. Oza. (2022) Comprehensive Review of Bioactive and Molecular Aspects of Moringa Oleifera Lam. Food Reviews International 38:7, pages 1427-1460.
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Fang Wang, Yifan Bao, Chen Zhang, Libin Zhan, Washim Khan, Sahifa Siddiqua, Sayeed Ahmad, Esra Capanoglu, Krystyna Skalicka-Woźniak, Liang Zou, Jesus Simal-Gandara, Hui Cao, Zebin Weng, Xinchun Shen & Jianbo Xiao. (2022) Bioactive components and anti-diabetic properties of Moringa oleifera Lam. Critical Reviews in Food Science and Nutrition 62:14, pages 3873-3897.
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Christian K. O. Dzuvor, Sharadwata Pan, Charles Amanze, Prosper Amuzu, Charles Asakiya & Francis Kubi. (2022) Bioactive components from Moringa oleifera seeds: production, functionalities and applications – a critical review. Critical Reviews in Biotechnology 42:2, pages 271-293.
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Seetha Jaswanth, Mallavarapu Umamahesh, Gajjala Raghavendra Reddy, Gollapudi Venkata Ramanamurthy, Akepogu Prasad & Anumakonda Varada Rajulu. (2021) In situ generation of antibacterial copper nanocomposite fabrics by bioreduction with Moringa oliefiera leaf extract. Inorganic and Nano-Metal Chemistry 51:2, pages 259-266.
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Sithandiwe Ntila, Ashwell R. Ndhlala, Unathi Kolanisi, Hafiz Abdelgadir & Muthulisi Siwela. (2019) Acceptability of a moringa-added complementary soft porridge to caregivers in Hammanskraal, Gauteng province and Lebowakgomo, Limpopo province, South Africa. South African Journal of Clinical Nutrition 32:3, pages 51-57.
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Abubakar Amali Muhammad, Palanisamy Arulselvan, Pike See Cheah, Farida Abas & Sharida Fakurazi. (2016) Evaluation of wound healing properties of bioactive aqueous fraction from Moringa oleifera Lam on experimentally induced diabetic animal model. Drug Design, Development and Therapy 10, pages 1715-1730.
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Kemika Praengam, Chawanphat Muangnoi, Suwitcha Dawilai, Monwirin Awatchanawong & Siriporn Tuntipopipat. (2015) Digested Moringa oleifera Boiled Pod Exhibits Anti-Inflammatory Activity in Caco-2 Cells. Journal of Herbs, Spices & Medicinal Plants 21:2, pages 148-160.
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Amar Jyoti Das. (2012) Moringa oleifera (Lamm.): A Plant with Immense Importance. Journal of Biologically Active Products from Nature 2:5, pages 307-315.
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Shailaja G. Mahajan & Anita A. Mehta. (2009) Anti-Arthritic Activity of Hydroalcoholic Extract of Flowers of Moringa oleifera Lam. in Wistar Rats. Journal of Herbs, Spices & Medicinal Plants 15:2, pages 149-163.
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Shailaja G. Mahajan & Anita A. Mehta. (2008) Effect of Moringa oleifera Lam. Seed Extract on Ovalbumin-Induced Airway Inflammation in Guinea Pigs. Inhalation Toxicology 20:10, pages 897-909.
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Shailaja G. Mahajan & Anita A. Mehta. (2007) Inhibitory Action of Ethanolic Extract of Seeds of Moringa oleifera Lam. On Systemic and Local Anaphylaxis. Journal of Immunotoxicology 4:4, pages 287-294.
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Shailaja G. Mahajan, Ravindra G. Mali & Anita A. Mehta. (2007) Effect of Moringa oleifera Lam. Seed Extract on Toluene Diisocyanate-Induced Immune-Mediated Inflammatory Responses in Rats. Journal of Immunotoxicology 4:2, pages 85-96.
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Kanchit Rongchai, Titikan Somboon & Suparerk Charmongkolpradit. (2022) Fluidized bed drying behaviour of moringa leaves and the influence of temperature on the calcium content. Case Studies in Thermal Engineering 40, pages 102564.
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B.N. Tate & C.N. Mowa. (2020) Proteomic analysis of Moringa oleifera's anti-arthritic effects on human fibroblasts-like synoviocytes. South African Journal of Botany 129, pages 324-335.
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Shad Mahfuz & Xiang Shu Piao. (2019) Application of Moringa(Moringa oleifera) as Natural Feed Supplement in Poultry Diets. Animals 9:7, pages 431.
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Can Cui, Song Chen, Xinyu Wang, Guangwei Yuan, Feng Jiang, Xiaoyang Chen & Lei Wang. (2019) Characterization of Moringa oleifera roots polysaccharide MRP-1 with anti-inflammatory effect. International Journal of Biological Macromolecules 132, pages 844-851.
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Yeong-Geun Lee, Hwan Lee, Jin Ah Ryuk, Joo Tae Hwang, Hyoung-Geun Kim, Dong-Sung Lee, Yeon-Ju Kim, Deok-Chun Yang, Byoung Seob Ko & Nam-In Baek. (2019) 6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity. Bioorganic Chemistry 88, pages 102922.
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R.A. Drew. (2017) Collaboration between ISHS, GHI and the World Vegetable Center in response to world poverty and malnutrition and the role of moringa as a nutrient rich food. Acta Horticulturae:1158, pages 11-14.
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V. Kuete. 2017. Medicinal Spices and Vegetables from Africa. Medicinal Spices and Vegetables from Africa 485 496 .
Alessandro Leone, Alberto Spada, Alberto Battezzati, Alberto Schiraldi, Junior Aristil & Simona Bertoli. (2016) Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Health. International Journal of Molecular Sciences 17:12, pages 2141.
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Zhou Lan, Meng Wei, Lvyi Chen, Guangjing Xie, Xiao Liu & Xiuqiao Zhang. (2016) Role of Sinomenine on Complete Freund's Adjuvant-Induced Arthritis in Rats. IUBMB Life 68:6, pages 429-435.
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A. Godinez-Ov, N. Guemes-Ver & O.A. Acevedo-Sa. (2016) Nutritional and Phytochemical Composition of Moringa oleifera Lam and its Potential Use as Nutraceutical Plant: A Review. Pakistan Journal of Nutrition 15:4, pages 397-405.
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K. Vasanth, G.C. Minakshi, K. Ilango, R.Mohan Kumar, Aruna Agrawal & G.P. Dubey. (2015) Moringa oleifera attenuates the release of pro-inflammatory cytokines in lipopolysaccharide stimulated human monocytic cell line. Industrial Crops and Products 77, pages 44-50.
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Abdulrahman L. Al-Malki & Haddad A. El Rabey. (2015) The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats . BioMed Research International 2015, pages 1-13.
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Il Lae Jung. (2014) Soluble Extract from Moringa oleifera Leaves with a New Anticancer Activity. PLoS ONE 9:4, pages e95492.
Crossref
Ji-Sun Shin, Chang Hyeon Yun, Kyung-Sook Chung, Myun-Ho Bang, Nam-In Baek, Hae-Gon Chung, Young-Wuk Cho & Kyung-Tae Lee. (2014) Standardized ethyl acetate fraction from the roots of Brassica rapa attenuates the experimental arthritis by down regulating inflammatory responses and inhibiting NF-κB activation. Food and Chemical Toxicology 66, pages 96-106.
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Hyun-Ji Cho & Young-Chae Chang. (2014) Extract of Moringa Root Inhibits PMA-induced Invasion of Breast Cancer Cells. Journal of Life Science 24:1, pages 8-13.
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Kartick K. Samanta, S. Basak & S. K. Chattopadhyay. 2014. Roadmap to Sustainable Textiles and Clothing. Roadmap to Sustainable Textiles and Clothing 263 287 .
Suresh Kumar GuptaBinit KumarB.P. SrinivasanTapas Chandra NagSushma SrivastavaRohit SaxenaAshutosh Aggarwal. (2013) Retinoprotective Effects of Moringa oleifera via Antioxidant, Anti-Inflammatory, and Anti-Angiogenic Mechanisms in Streptozotocin-Induced Diabetic Rats . Journal of Ocular Pharmacology and Therapeutics 29:4, pages 419-426.
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Abubakar Amali Muhammad, Nur Aimi Syarina Pauzi, Palanisamy Arulselvan, Faridah Abas & Sharida Fakurazi. (2013) In Vitro Wound Healing Potential and Identification of Bioactive Compounds from Moringa oleifera Lam . BioMed Research International 2013, pages 1-10.
Crossref
Nilanjan Das, Kunal Sikder, Surajit Bhattacharjee, Suchandra Bhattacharya Majumdar, Santinath Ghosh, Subrata Majumdar & Sanjit Dey. (2013) Quercetin alleviates inflammation after short-term treatment in high-fat-fed mice. Food & Function 4:6, pages 889.
Crossref
Bishambar Dayal, Vineela Reddy Yannamreddy, Ritesh Amin, Michael A. Lea & Athula B. Attygalle. 2013. Tropical and Subtropical Fruits: Flavors, Color, and Health Benefits. Tropical and Subtropical Fruits: Flavors, Color, and Health Benefits 203 219 .
Mansour S. Al-Said, Ramzi A. Mothana, Mohammed A. Al-Yahya, Ali S. Al-Blowi, Mohammed Al-Sohaibani, Atallah F. Ahmed & Syed Rafatullah. (2012) Edible Oils for Liver Protection: Hepatoprotective Potentiality of Moringa Oleifera Seed Oil against Chemical-Induced Hepatitis in Rats. Journal of Food Science 77:7, pages T124-T130.
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Channarong Muangnoi, Pimjai Chingsuwanrote, Phawachaya Praengamthanachoti, Saovaros Svasti & Siriporn Tuntipopipat. (2011) Moringa oleifera Pod Inhibits Inflammatory Mediator Production by Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage Cell Lines. Inflammation 35:2, pages 445-455.
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Ghanshyam B. Dudhatra, Shailesh K. Mody, Madhavi M. Awale, Hitesh B. Patel, Chirag M. Modi, Avinash Kumar, Divyesh R. Kamani & Bhavesh N. Chauhan. (2012) A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers. The Scientific World Journal 2012, pages 1-33.
Crossref
T. K. LimT. K. Lim. 2012. Edible Medicinal And Non Medicinal Plants. Edible Medicinal And Non Medicinal Plants 453 485 .
N. M. Abdel-Moein, E. A. Abdel-Moniem, D. A. Mohamed & E. A. Hanfy. (2011) Evaluation of the anti-inflammatory and anti-arthritic effects of some plant extracts. Grasas y Aceites 62:4, pages 365-374.
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Bobbie Posmontier. (2011) The Medicinal Qualities of Moringa Oleifera. Holistic Nursing Practice 25:2, pages 80-87.
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Shailaja G. Mahajan & Anita A. Mehta. (2011) Suppression of ovalbumin-induced Th2-driven airway inflammation by β-sitosterol in a guinea pig model of asthma. European Journal of Pharmacology 650:1, pages 458-464.
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Shailaja G. Mahajan & Anita A. Mehta. (2010) Immunosuppressive activity of ethanolic extract of seeds of Moringa oleifera Lam. in experimental immune inflammation. Journal of Ethnopharmacology 130:1, pages 183-186.
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Shailaja G. MahajanAryamitra BanerjeeBhupendrasinh F. ChauhanHarish PadhManish NivsarkarAnita A. Mehta. (2009) Inhibitory Effect of n-butanol Fraction of Moringa oleifera Lam. Seeds on Ovalbumin-Induced Airway Inflammation in a Guinea Pig Model of Asthma . International Journal of Toxicology 28:6, pages 519-527.
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